Page last updated: 2024-09-28

Adult Sandhoff Disease

Synonyms(19)

Synonym
beta-Hexosaminidase-beta-Subunit Deficiency
Hexosaminidase A and B Deficiency Disease
Adult Sandhoff Disease
GM2-Gangliosidosis, Type II
GM2 Gangliosidosis, Type 2
Deficiency Disease, Hexosaminidase A and B
Sandhoff Disease, Adult
Sandhoff Disease, Juvenile
Gangliosidosis G(M2), Type II
GM2 Gangliosidosis, Type II
Total Hexosaminidase Deficiency
Juvenile Sandhoff Disease
Hexosaminidases A And B Deficiency
Sandhoff's Disease
Sandhoff Disease, Infantile
Gangliosidosis GM2, Type II
Sandhoff-Jatzkewitz-Pilz Disease
Infantile Sandhoff Disease
G(M2) Gangliosidosis, Type II

Research Excerpts

Research

Studies (149)

TimeframeStudies, This Condition (%)All Conditions %
pre-199039 (26.17)23.3326
1990's31 (20.81)12.5806
2000's48 (32.21)18.1394
2010's22 (14.77)28.8240
2020's9 (6.04)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
carbamates0low10
choline0low10
3-hydroxybutyric acid0low20
cytosine0low10
spermine0low10
acetyl-dl-leucine0medium32
amitriptyline0low10
gabapentin0low10
haloperidol0low10
ethidium0low10
loperamide0low10
pyrimethamine0low10
stearic acid0low10
corticosterone0low10
serine0low30
glutamine0low10
sucrose0low20
tyrosine0low20
leucine0low10
cycloheximide0low10
mannitol0low10
arginine0low30
taurocholic acid0low20
quinuclidines0low10
pyrroles0low10
2-naphthol0low10
fucose0low20
sabinene0low10
mannose0low30
acetylglucosamine0low70
galactose0low10
ammonium chloride0low10
1-deoxynojirimycin0low170
phenyl acetate0low10
ursodeoxycholic acid0low10
4-methoxyamphetamine0low10
acetylgalactosamine0low10
miglustat0low110
naphthalimides0low10
naphthol as0low10
leupeptin0low10
2-acetamido-2-deoxy-d-glucono-(1,5)-lactone0low10
4-methylumbelliferyl glucuronide0low10
fingolimod hydrochloride0low10
1-phenyl-2-decanoylamino-3-morpholino-1-propanol0low10
4-methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-beta-glucopyranoside0low30
proline0low20
biotin0low10
migalastat0low60
2-(2-oxolanylmethyl)benzo[de]isoquinoline-1,3-dione0low10
leupeptins0low10
mannose-6-phosphate0low10
glucosamine0low20
n-acetylglucosamine-6-sulfate0low10
retinol0low10
thapsigargin0low10
keratan sulfate0low10
isomethyleugenol0low10
myelin basic protein0low10
sphingosine0low20
dinoprostone0low30
hymecromone0low50
genistein0low10
nervonic acid0low10
sphingosine 1-phosphate0low10
su 54020low10
cysteine0low10
g(m2) ganglioside0low690
g(m1) ganglioside0low80
alpha-synuclein0low50
phosphatidylcholines0low10
sphingosine kinase0low10
glycolipids0low90
chondroitin0low10
chondroitin sulfates0low10
ganglio-n-triaosylceramide0low20
guanosine0low10
eye0low10
concanavalin a0low30

Protein Targets (889)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
glucocerebrosidase7007
Alpha-mannosidase0202
alpha-galactosidase6006
Trehalase 0202
lysosomal alpha-glucosidase preproprotein3003
Trehalase0101
Maltase-glucoamylase, intestinal0505
Trehalase 0202
Lysosomal acid glucosylceramidase0404
Alpha-galactosidase A0202
Alpha-glucosidase MAL620101
Lactase-phlorizin hydrolase0303
Lysosomal alpha-glucosidase0505
Beta-glucosidase A0202
Sucrase-isomaltase, intestinal0303
Alpha-1B adrenergic receptor0303
Sucrase-isomaltase, intestinal0202
Alpha-1D adrenergic receptor0303
Beta-glucosidase0101
Protein-lysine 6-oxidase0404
Alpha-mannosidase 20202
Glycogen debranching enzyme0303
Glycogen debranching enzyme0101
Alpha-glucosidase MAL320202
Alpha-1A adrenergic receptor0404
Oligo-1,6-glucosidase IMA10101
Alpha-glucosidase MAL120202
Oxysterols receptor LXR-beta0202
Spike glycoprotein5027
Alpha-amylase 0101
Trehalose synthase/amylase TreS0101
Lactase-phlorizin hydrolase 0303
Oxysterols receptor LXR-alpha0202
Neutral alpha-glucosidase AB0202
Ceramide glucosyltransferase0303
Lysosomal acid glucosylceramidase0101
Probable maltase-glucoamylase 20101
Beta-glucosidase 0101
Lysosomal alpha-glucosidase0202
Cytosolic beta-glucosidase0101
Non-lysosomal glucosylceramidase0303
Putative alpha-glucosidase0202
Chain A, 2-oxoglutarate Oxygenase4004
thioredoxin reductase120012
TDP1 protein140014
aldehyde dehydrogenase 1 family, member A1100010
nuclear factor erythroid 2-related factor 2 isoform 24004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor4004
DNA polymerase iota isoform a (long)5005
muscleblind-like protein 1 isoform 11001
Beta-hexosaminidase subunit alpha0304
Chain A, Hyaluronoglucosaminidase0101
Luciferase3003
RAR-related orphan receptor gamma130013
GLI family zinc finger 3140014
AR protein110011
estrogen receptor 2 (ER beta)8008
nuclear receptor subfamily 1, group I, member 39009
progesterone receptor7007
retinoic acid nuclear receptor alpha variant 1110011
retinoid X nuclear receptor alpha9009
pregnane X nuclear receptor8008
estrogen nuclear receptor alpha160016
peroxisome proliferator-activated receptor delta9009
aryl hydrocarbon receptor4004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a7007
v-jun sarcoma virus 17 oncogene homolog (avian)4004
Histone H2A.x5005
thyroid hormone receptor beta isoform 29009
nuclear factor erythroid 2-related factor 2 isoform 1120012
DNA repair and recombination protein RadA0011
Voltage-dependent calcium channel gamma-2 subunit7007
Cellular tumor antigen p53100010
Cytochrome P450 1A20101
Cytochrome P450 2A60101
Sulfotransferase 1A1 0001
Glutamate receptor 27007
Cytochrome P450 2A50101
Sulfotransferase 1E10001
Sulfotransferase 1A10001
Sulfotransferase 2A10001
Protein skinhead-10101
Monocarboxylate transporter 20101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
5-hydroxytryptamine receptor 2C0415
5-hydroxytryptamine receptor 2A0415
5-hydroxytryptamine receptor 1A0516
5-hydroxytryptamine receptor 1B0415
5-hydroxytryptamine receptor 1D0314
5-hydroxytryptamine receptor 1F0314
5-hydroxytryptamine receptor 2B0415
5-hydroxytryptamine receptor 60112
Sodium-dependent serotonin transporter0729
Sodium-dependent serotonin transporter0303
5-hydroxytryptamine receptor 7 0213
5-hydroxytryptamine receptor 5A0112
5-hydroxytryptamine receptor 5B0112
5-hydroxytryptamine receptor 3A0112
5-hydroxytryptamine receptor 4 0112
5-hydroxytryptamine receptor 3B0112
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
mitogen-activated protein kinase 16006
chromobox protein homolog 19009
geminin150015
Fibrinogen C domain-containing protein 10101
Putative glycosyltransferase WbgO0001
Cytochrome P450 3A40316
Cannabinoid receptor 10202
Killer cell lectin-like receptor subfamily B member 1A0101
Early activation antigen CD690101
USP1 protein, partial7007
NFKB1 protein, partial4004
GLS protein5005
cytochrome P450 family 3 subfamily A polypeptide 46006
cytochrome P450 2D65005
arylsulfatase A6006
cytochrome P450 2D6 isoform 14004
D(1A) dopamine receptor4004
atrial natriuretic peptide receptor 2 precursor3003
serine/threonine-protein kinase mTOR isoform 15005
muscarinic acetylcholine receptor M18008
Solute carrier family 22 member 1 0608
Polyunsaturated fatty acid lipoxygenase ALOX15B4004
ATP-binding cassette sub-family C member 30202
Multidrug resistance-associated protein 40304
Voltage-dependent L-type calcium channel subunit alpha-1F0202
5-hydroxytryptamine receptor 40606
Bile salt export pump0708
Albumin0022
High affinity nerve growth factor receptor0123
Aldo-keto reductase family 1 member B10505
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40303
Muscarinic acetylcholine receptor M10303
Muscarinic acetylcholine receptor M30303
Muscarinic acetylcholine receptor M40303
Muscarinic acetylcholine receptor M50303
Muscarinic acetylcholine receptor M50404
Alpha-2A adrenergic receptor0404
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M10404
Angiotensin-converting enzyme0303
D(2) dopamine receptor0518
Alpha-2B adrenergic receptor0404
Alpha-2C adrenergic receptor0404
Muscarinic acetylcholine receptor M30303
D(1A) dopamine receptor0405
D(1B) dopamine receptor0304
UDP-glucuronosyltransferase 1A40002
Sodium-dependent noradrenaline transporter 0404
Histamine H2 receptor0606
Alpha-1D adrenergic receptor0404
5-hydroxytryptamine receptor 2A0606
5-hydroxytryptamine receptor 2C0606
Histamine H1 receptor0303
Histamine H1 receptor0404
D(3) dopamine receptor0619
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 4 subunit alpha0202
UDP-glucuronosyltransferase 1A30001
5-hydroxytryptamine receptor 2B0606
Histamine H2 receptor61010
D(1A) dopamine receptor4105
5-hydroxytryptamine receptor 60303
5-hydroxytryptamine receptor 70303
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Sodium channel protein type 7 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Sodium-dependent dopamine transporter 0404
Potassium voltage-gated channel subfamily H member 20505
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0303
Sodium channel protein type 9 subunit alpha0202
Sigma non-opioid intracellular receptor 10112
Nuclear receptor subfamily 3 group C member 3 0202
Canalicular multispecific organic anion transporter 10202
Sodium channel protein type 2 subunit alpha0202
Ataxin-27007
Sigma non-opioid intracellular receptor 10707
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0202
Sodium channel protein type 8 subunit alpha0202
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0202
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
phosphopantetheinyl transferase5005
thyroid stimulating hormone receptor9009
euchromatic histone-lysine N-methyltransferase 2110011
cytochrome P450 2C19 precursor3003
flap endonuclease 14004
lethal factor (plasmid)6006
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase7007
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, JmjC domain-containing histone demethylation protein 3A1001
apical membrane antigen 1, AMA12002
nonstructural protein 10101
green fluorescent protein, partial0101
vitamin D3 receptor isoform VDRA5005
insulin-degrading enzyme isoform 10011
Streptavidin0011
Receptor-type tyrosine-protein phosphatase beta0001
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10203
Solute carrier family 22 member 20103
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-40101
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Acetylcholinesterase0101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Solute carrier family 22 member 10304
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20304
pregnane X receptor4004
GALC protein3003
Thrombopoietin5005
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
nonstructural protein 12002
glucocorticoid receptor [Homo sapiens]120012
estrogen-related nuclear receptor alpha120012
farnesoid X nuclear receptor8008
G4004
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
IDH15005
thyroid stimulating hormone receptor5005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
thyroid hormone receptor beta isoform a7007
heat shock protein beta-13003
survival motor neuron protein isoform d6006
cytochrome P450 3A4 isoform 17007
Gamma-aminobutyric acid receptor subunit pi7209
Solute carrier family 22 member 30101
Solute carrier family 22 member 30101
Interferon beta8008
HLA class I histocompatibility antigen, B alpha chain 4004
Sex hormone-binding globulin0022
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0011
Androgen receptor0202
Gamma-aminobutyric acid receptor subunit beta-17209
Gamma-aminobutyric acid receptor subunit delta7209
Gamma-aminobutyric acid receptor subunit gamma-272110
Gamma-aminobutyric acid receptor subunit alpha-57209
Gamma-aminobutyric acid receptor subunit alpha-37209
Gamma-aminobutyric acid receptor subunit gamma-17209
Gamma-aminobutyric acid receptor subunit alpha-27209
Gamma-aminobutyric acid receptor subunit alpha-47209
Gamma-aminobutyric acid receptor subunit gamma-37209
Gamma-aminobutyric acid receptor subunit alpha-67209
C-8 sterol isomerase0202
Solute carrier organic anion transporter family member 1A10203
Nuclear receptor ROR-gamma4004
Gamma-aminobutyric acid receptor subunit alpha-172110
Gamma-aminobutyric acid receptor subunit beta-37209
Gamma-aminobutyric acid receptor subunit beta-272110
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0202
GABA theta subunit7209
Inositol hexakisphosphate kinase 14004
Gamma-aminobutyric acid receptor subunit epsilon7209
cytochrome P450 2C9, partial4004
interleukin 82002
glp-1 receptor, partial4004
ATAD5 protein, partial7007
Fumarate hydratase4004
PPM1D protein5005
Smad33003
EWS/FLI fusion protein7007
polyprotein4004
67.9K protein4004
P532002
peroxisome proliferator activated receptor gamma6006
RPL19A0011
activating transcription factor 65005
Spike glycoprotein0022
Replicase polyprotein 1ab0022
NPC intracellular cholesterol transporter 1 precursor3003
cellular tumor antigen p53 isoform a4004
nuclear factor NF-kappa-B p105 subunit isoform 12002
ras-related protein Rab-9A4004
heat shock protein HSP 90-alpha isoform 20001
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
nuclear receptor ROR-gamma isoform 16006
transactivating tegument protein VP16 [Human herpesvirus 1]0101
COUP transcription factor 2 isoform a0101
Transmembrane protease serine 20022
Glucose transporter0101
Hexose transporter 1 0101
Procathepsin L0123
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0123
Solute carrier family 2, facilitated glucose transporter member 10202
Alpha-synuclein2103
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
TAR DNA-binding protein 435005
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0101
ATPase family AAA domain-containing protein 55005
Endothelial PAS domain-containing protein 10101
Angiotensin-converting enzyme 2 0022
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0001
Deoxycytidine kinase0001
Chain A, Cruzipain3003
SMAD family member 26006
SMAD family member 36006
regulator of G-protein signaling 44004
prostaglandin E2 receptor EP2 subtype1001
peripheral myelin protein 228008
Solute carrier organic anion transporter family member 1A50002
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 60001
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 80001
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110001
Solute carrier organic anion transporter family member 1B20002
Solute carrier family 22 member 70001
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Microtubule-associated protein tau4004
Bloom syndrome protein isoform 16006
DNA polymerase kappa isoform 14004
histone acetyltransferase KAT2A isoform 13003
Reverse transcriptase/RNaseH 0101
Sphingosine 1-phosphate receptor 10123
RCG53912, isoform CRA_a 0001
Sphingosine kinase 1 0001
Sphingosine kinase 20102
Sphingosine kinase 10102
Fucose-binding lectin PA-IIL0202
CD209 antigen0303
thioredoxin glutathione reductase1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
lamin isoform A-delta109009
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Chain A, Ferritin light chain4004
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
bromodomain adjacent to zinc finger domain 2B1001
transcriptional regulator ERG isoform 32002
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
neuropeptide S receptor isoform A1001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Histone deacetylase 30101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-50112
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit beta-20112
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit beta-10011
Histone deacetylase 40101
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit epsilon0101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Histone deacetylase 10101
Gamma-aminobutyric acid receptor subunit alpha-60112
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10405
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0011
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Gamma-aminobutyric acid receptor subunit gamma-30101
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Histone deacetylase 60101
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90101
Gamma-aminobutyric acid receptor subunit theta0101
Histone deacetylase 50101
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Estrogen receptor 1 (alpha)0101
Chain A, Transthyretin0011
Chain A, Transthyretin0011
acid sphingomyelinase2002
BRCA11001
15-lipoxygenase, partial8008
Neuraminidase 0101
Parkin2002
pyruvate kinase1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
hexokinase-4 isoform 11001
peripheral myelin protein 22 isoform 13003
cytochrome P450 2C9 precursor3003
histone deacetylase 9 isoform 31001
glucokinase regulatory protein1001
glycogen synthase kinase-3 beta isoform 10011
DNA polymerase beta2002
tyrosine-protein kinase Yes1001
M-phase phosphoprotein 81001
pyruvate kinase PKM isoform b1001
Steroid hormone receptor ERR20101
Tyrosine-protein kinase ABL10101
Epidermal growth factor receptor0202
Pancreatic triacylglycerol lipase0101
Triosephosphate isomerase0101
Transthyretin0101
Estrogen receptor0213
Glucocorticoid receptor0012
Integrin beta-32002
Tyrosine-protein kinase Fyn0101
Cyclin-dependent kinase 10101
ATP-dependent translocase ABCB10316
Integrin alpha-IIb2002
Ornithine decarboxylase1001
Androgen receptor0102
Sialidase0101
Tyrosinase0101
Steroid hormone receptor ERR10101
Aromatase0101
Cyclin-dependent kinase 40101
Ornithine decarboxylase0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Proto-oncogene tyrosine-protein kinase Src0202
Cystic fibrosis transmembrane conductance regulator0011
17-beta-hydroxysteroid dehydrogenase type 10101
Solute carrier family 2, facilitated glucose transporter member 40101
G2/mitotic-specific cyclin-B10101
Dipeptidyl peptidase 40101
Aldo-keto reductase family 1 member B10202
Protein kinase C alpha type0101
cAMP-dependent protein kinase catalytic subunit alpha0101
Amine oxidase [flavin-containing] A 0101
Amine oxidase [flavin-containing] A0101
Amine oxidase [flavin-containing] A 0101
Prostaglandin G/H synthase 10101
G1/S-specific cyclin-D10101
Thromboxane-A synthase 0101
Cruzipain0101
DNA (cytosine-5)-methyltransferase 10101
Amine oxidase [flavin-containing] B0202
Dipeptidyl peptidase 40202
Proteasome subunit beta type-50101
Adenosine receptor A2a0202
Adenosine receptor A10202
Adenosine receptor A2a0102
Substance-P receptor0101
RAC-alpha serine/threonine-protein kinase0101
Cystic fibrosis transmembrane conductance regulator0011
Testosterone 17-beta-dehydrogenase 30202
17-beta-hydroxysteroid dehydrogenase type 20101
Acetylcholinesterase0101
Signal transducer and activator of transcription 30101
Tyrosine-protein kinase CSK0101
Tyrosine-protein kinase ABL20101
Tyrosine-protein kinase SYK0101
Dual specificity mitogen-activated protein kinase kinase 40101
Quinone oxidoreductase0001
Xanthine dehydrogenase/oxidase0101
Cytoplasmic tyrosine-protein kinase BMX0101
Death-associated protein kinase 10101
Mitogen-activated protein kinase 100101
Amine oxidase [flavin-containing] B0101
Xanthine dehydrogenase/oxidase0101
MO15-related protein kinase Pfmrk 0101
Aldehyde oxidase0101
Mitogen-activated protein kinase 140101
Tissue alpha-L-fucosidase0101
Substance-K receptor0101
Integrase 0101
Estrogen receptor beta0213
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)0101
Prenyltransferase homolog0001
Carboxylic ester hydrolase 0101
Solute carrier organic anion transporter family member 1B30203
Dipeptidyl peptidase 30101
DNA (cytosine-5)-methyltransferase 3-like0101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Sialidase-20101
DNA (cytosine-5)-methyltransferase 3A0101
Solute carrier organic anion transporter family member 1B10203
Chain A, Glutamine Binding Protein0011
Carbonic anhydrase 10204
Carbonic anhydrase 20316
Neutral amino acid transporter A0303
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0303
Carbonic anhydrase-like protein, putative0002
Amino acid transporter0303
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Purine nucleoside phosphorylase0001
Adenosylhomocysteinase0102
acetylcholinesterase4004
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
Adenylate cyclase type 1 0101
potassium voltage-gated channel subfamily H member 2 isoform d6006
transient receptor potential cation channel subfamily V member 11001
Cocaine esterase0303
Transient receptor potential cation channel subfamily V member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
UDP-glucuronosyltransferase 1A90102
Potassium channel subfamily K member 20101
Major prion protein0011
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10101
5-hydroxytryptamine receptor 1A0202
Beta-2 adrenergic receptor0202
Cytochrome P450 2C9 0202
Integrin alpha-40101
Carbonyl reductase [NADPH] 10001
UDP-glucuronosyltransferase 2B70102
Beta-1 adrenergic receptor0101
D0202
D(3) dopamine receptor0202
Alpha-2B adrenergic receptor0101
D(2) dopamine receptor0202
D(4) dopamine receptor0316
Adenylate cyclase type 30101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Sodium-dependent dopamine transporter0202
5-hydroxytryptamine receptor 3A0101
Adenosine receptor A10102
D(1B) dopamine receptor0202
Beta-3 adrenergic receptor0101
Adenylate cyclase type 20101
Adenylate cyclase type 40101
D(4) dopamine receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0202
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Kappa-type opioid receptor0101
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 2A0101
Alpha-1B adrenergic receptor0101
Mu-type opioid receptor0415
Glutamate receptor ionotropic, NMDA 1 0315
Adenylate cyclase type 80101
Kappa-type opioid receptor0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 2J20101
D(2) dopamine receptor0101
D(3) dopamine receptor0101
Gastrin/cholecystokinin type B receptor0101
D(2) dopamine receptor0202
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
Glutamate receptor ionotropic, NMDA 2A 0203
Glutamate receptor ionotropic, NMDA 2B0214
Glutamate receptor ionotropic, NMDA 2C0203
5-hydroxytryptamine receptor 2B0101
Adenylate cyclase type 60101
Adenylate cyclase type 50101
5-hydroxytryptamine receptor 40101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20101
Sigma intracellular receptor 20101
Zinc finger protein 6640101
Glutamate receptor ionotropic, NMDA 2D0203
Vesicular acetylcholine transporter0101
Transporter0101
Cholecystokinin receptor type A0101
Protease 0202
Adenylyl cyclase 7 0101
Glutamate receptor ionotropic, NMDA 3B0203
D0101
Transient receptor potential cation channel subfamily V member 40101
Sigma non-opioid intracellular receptor 10202
Glutamate receptor ionotropic, NMDA 3A0203
Transient receptor potential cation channel subfamily V member 20101
hypoxia-inducible factor 1 alpha subunit1001
importin subunit beta-1 isoform 11001
snurportin-11001
caspase-1 isoform alpha precursor1001
Acetylcholinesterase0404
Carbonic anhydrase 120203
Nuclear factor NF-kappa-B p105 subunit0101
UDP-glucuronosyltransferase 1A1 0101
Genome polyprotein0101
Caspase-71001
Small conductance calcium-activated potassium channel protein 30101
Cholinesterase0202
Sorbitol dehydrogenase0101
Induced myeloid leukemia cell differentiation protein Mcl-10202
Carbonic anhydrase 90315
Oleandomycin glycosyltransferase0001
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Large neutral amino acids transporter small subunit 10202
Phospholipase A-2-activating protein0101
Cathepsin B 0101
Prothrombin 0101
Plasminogen0101
Cationic trypsin0101
Trypsin0101
Papain0101
Plasma kallikrein0102
Serine protease hepsin0101
Plasminogen 0101
Trypsin-10101
Trypsin-20101
Cathepsin B0101
Cathepsin B0202
Pro-cathepsin H0101
Trypsin-30101
Calpain-1 catalytic subunit0101
Cathepsin K0101
Hepatocyte growth factor activator0101
Transmembrane protease serine 60101
Cysteine protease0101
Cysteine proteinase falcipain 2a 0101
Cysteine protease falcipain-30101
Suppressor of tumorigenicity 14 protein0101
polyunsaturated fatty acid lipoxygenase ALOX121001
huntingtin isoform 21001
Menin0101
Beta-2 adrenergic receptor0202
Cytochrome P450 2D60101
Delta-type opioid receptor0213
Kappa-type opioid receptor0202
Nociceptin receptor0101
Calmodulin 0112
Disintegrin and metalloproteinase domain-containing protein 172002
Mu-type opioid receptor0112
Inositol monophosphatase 11001
Angiopoietin-1 receptor0011
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Alpha-mannosidase 2C10101
Beta-galactosidase 0101
Beta-galactosidase0202
Alpha-galactosidase0202
Beta-galactosidase0101
Beta-galactosidase0101
Alpha-galactosidase C0101
Sucrase-isomaltase 0101
Ceramide glucosyltransferase0101
Beta-galactosidase0101
Lysosomal alpha-glucosidase0101
Non-lysosomal glucosylceramidase0101
Chain A, Cholix toxin0101
Poly [ADP-ribose] polymerase 10101
DNA polymerase catalytic subunit0101
Glutamate 5-kinase0001
Angiotensin-converting enzyme 0101
dual specificity protein phosphatase 30101
low molecular weight phosphotyrosine protein phosphatase isoform c0101
tyrosine-protein phosphatase non-receptor type 22 isoform 10101
streptokinase A precursor0022
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0202
Dihydrofolate reductase 0101
Estrogen receptor0022
Beta-hexosaminidase subunit beta0101
Dihydrofolate reductase0214
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0202
Substance-K receptor0101
Dihydrofolate reductase0101
Low molecular weight phosphotyrosine protein phosphatase0101
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trace amine-associated receptor 50011
Estrogen receptor beta0022
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Multidrug and toxin extrusion protein 10101
Dihydrofolate reductase0101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Amyloid-beta precursor protein0101
Pyruvate kinase PKM0011
dopamine D1 receptor1001
Carbonic anhydrase 30102
DNA topoisomerase 2-alpha0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
Carbonic anhydrase 40102
Carbonic anhydrase 60102
Carbonic anhydrase 5A, mitochondrial0102
Caspase-20011
Carbonic anhydrase 70102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Glutamate receptor ionotropic, NMDA 2B0011
Carbonic anhydrase 150102
Carbonic anhydrase 130101
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
endonuclease IV1001
C-X-C chemokine receptor type 5 isoform 10101
ubiquitin-conjugating enzyme E2 N0101
C-C chemokine receptor type 60101
apelin receptor0101
DNA polymerase eta isoform 11001
bcl-2-related protein A10101
Endoglycoceramidase II 0001
Protein kinase C alpha type0101
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
cAMP-dependent protein kinase catalytic subunit alpha 0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Protein kinase C eta type0101
Protein kinase C theta type0101
Sphingosine 1-phosphate receptor 20112
Sphingosine 1-phosphate receptor 40112
Sphingosine 1-phosphate receptor 30112
Sphingosine 1-phosphate receptor 50112
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Prostaglandin G/H synthase 1 0101
Fatty acid-binding protein, adipocyte0011
Tyrosine-protein phosphatase non-receptor type 10101
Prostaglandin G/H synthase 20101
Peroxisome proliferator-activated receptor alpha0011
Receptor tyrosine-protein kinase erbB-20101
Insulin-like growth factor 1 receptor0101
Platelet-derived growth factor receptor beta0101
Fibroblast growth factor receptor 10101
Fibroblast growth factor receptor 10101
Vascular endothelial growth factor receptor 20101
Vascular endothelial growth factor receptor 10101
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Sodium/bile acid cotransporter0001
Solute carrier organic anion transporter family member 1A40203
Solute carrier family 22 member 60101
Bile salt export pump0001
ATP-binding cassette sub-family C member 30001
Solute carrier organic anion transporter family member 2B1 0001
Sodium/bile acid cotransporter0102
Solute carrier organic anion transporter family member 1A20001
Ileal sodium/bile acid cotransporter0001
Solute carrier organic anion transporter family member 1A30102
Ileal sodium/bile acid cotransporter0203
Sodium/bile acid cotransporter0203
Ileal sodium/bile acid cotransporter0001
G-protein coupled bile acid receptor 10022
Solute carrier organic anion transporter family member0001
Solute carrier organic anion transporter family member 4A10001
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1C10101
Solute carrier organic anion transporter family member 2B10001
Solute carrier organic anion transporter family member 1A10001
Bile salt export pump0001
Solute carrier family 22 member 80101
DNA polymerase III, partial1001
atrial natriuretic peptide receptor 1 precursor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10112
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Polyphenol oxidase 20001
Carbonic anhydrase0001
Carbonic anhydrase0001
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Carbonic anhydrase 0001
Tubulin--tyrosine ligase0101
Monocarboxylate transporter 100001
Taste receptor type 2 member 140001
Chain A, Beta-lactamase1001
Ubiquitin carboxyl-terminal hydrolase 20101
Vitamin D3 receptor0112
Guanine nucleotide-binding protein G1001
Bile acid receptor0011
CDGSH iron-sulfur domain-containing protein 10202
M1-family alanyl aminopeptidase0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]