pyrimethamine has been researched along with Adult Sandhoff Disease in 1 studies
Maloprim: contains above 2 cpds
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sandhoff disease is an autosomal recessive inherited disorder resulting from β-hexosaminidase deficiency and characterized by large accumulation of GM2 ganglioside in brain." | 2.50 | Chaperone therapy for GM2 gangliosidosis: effects of pyrimethamine on β-hexosaminidase activity in Sandhoff fibroblasts. ( Aureli, M; Bassi, R; Caillaud, C; Chiricozzi, E; Emiliani, C; Loberto, N; Magini, A; Niemir, N; Polchi, A; Prinetti, A; Sonnino, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiricozzi, E | 1 |
| Niemir, N | 1 |
| Aureli, M | 1 |
| Magini, A | 1 |
| Loberto, N | 1 |
| Prinetti, A | 1 |
| Bassi, R | 1 |
| Polchi, A | 1 |
| Emiliani, C | 1 |
| Caillaud, C | 1 |
| Sonnino, S | 1 |
1 review available for pyrimethamine and Adult Sandhoff Disease
| Article | Year |
|---|---|
Chaperone therapy for GM2 gangliosidosis: effects of pyrimethamine on β-hexosaminidase activity in Sandhoff fibroblasts.
Topics: Fibroblasts; Hexosaminidase B; Humans; Molecular Chaperones; Pyrimethamine; Sandhoff Disease | 2014 |