Compounds > 2,7,4'-trihydroxyisoflavanone
Page last updated: 2024-11-12

2,7,4'-trihydroxyisoflavanone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,7,4'-trihydroxyisoflavanone: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

2,4',7-trihydroxyisoflavanone : A hydroxyisoflavanone that is isoflavanone with hydroxy substituents at positions 2, 7 and 4'. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID11954208
CHEBI ID52047
SCHEMBL ID571732
MeSH IDM0379056

Synonyms (8)

Synonym
2,7,4'-trihydroxyisoflavanone
2,4',7-trihydroxyisoflavanone
CHEBI:52047
2,7-dihydroxy-3-(4-hydroxyphenyl)-2,3-dihydro-4h-chromen-4-one
2,7-dihydroxy-3-(4-hydroxyphenyl)chroman-4-one
SCHEMBL571732
2,7-dihydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Q27123131
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
hydroxyisoflavanoneAny member of the class of isoflavanones with at least one hydroxy substituent.
lactolCyclic hemiacetals formed by intramolecular addition of a hydroxy group to an aldehydic or ketonic carbonyl group. They are thus 1-oxacycloalkan-2-ols or unsaturated analogues.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (5)

PathwayProteinsCompounds
superpathway of pterocarpan biosynthesis (via daidzein)022
superpathway of pterocarpan biosynthesis (via formononetin)031
isoflavonoid biosynthesis I014
formononetin biosynthesis011
Pterocarpan biosynthesis07

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.03

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.03 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.82 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.03)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
estragole
estragole : A phenylpropanoid that is chavicol in which the hydroxy group is replaced by a methoxy group.		2.0110alkenylbenzene;
monomethoxybenzene;
phenylpropanoid		carcinogenic agent;
flavouring agent;
genotoxin;
insect attractant;
plant metabolite
liquiritigenin
liquiritigenin: structure given in first source; isolated from Pterocarpus marsupium. 4',7-dihydroxyflavanone : A dihydroxyflavanone in which the two hydroxy substituents are located at positions 4' and 7.. liquiritigenin : A dihydroxyflavanone compound having the two hydroxy substituents at the 4'- and 7-positions. Isolated from the root of Glycyrrhizae uralensis, it is a selective agonist for oestrogen receptor beta.		2.41204',7-dihydroxyflavanonehormone agonist;
plant metabolite
medicarpin
(-)-medicarpin : The (-)-enantiomer of medicarpin.		210medicarpinplant metabolite
sesquiterpenes
[no description available]		2.4120
3-hydroxyflavanone
3-hydroxyflavanone: structure in first source. 3'-hydroxyflavanone : A monohydroxyflavanone in which the hydroxy group is located at position 3'.		2.01103'-hydroxyflavanones;
monohydroxyflavanone		metabolite
formononetin
[no description available]		7.7304'-methoxyisoflavones;
7-hydroxyisoflavones		phytoestrogen;
plant metabolite
daidzein
[no description available]		7.41207-hydroxyisoflavonesantineoplastic agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
phytoestrogen;
plant metabolite
ConditionIndicatedRelationship StrengthStudiesTrials