c-peptide and Cerebral-Small-Vessel-Diseases

To explore the correlation of serum c-peptide, soluble intercellular adhesion molecule-1 (sICAM-1), and NLRP3 inflammasome-related inflammatory factor interleukin-1. A total of 72 CSVD patients treated in our hospital from December 2018 to December 2019 were selected as the case group and another 72 patients who presented cerebrovascular risk factors but obtained normal brain MRI examination result in the same period were selected as the control group. The serum specimen of patients in the two groups were collected, their serum c-peptide levels were measured by radio immunoassay, and their serum sICAM-1 and NLRP3 inflammasome-related inflammatory factor IL-1. Compared with the control group, the level values of serum c-peptide, sICAM-1, and IL-1. Elevation of level values of serum c-peptide, sICAM-1, and NLRP3 inflammasome-related inflammatory factor IL-1

Topics: Brain; C-Peptide; Cerebral Small Vessel Diseases; Humans; Inflammasomes; Intercellular Adhesion Molecule-1; Interleukin-1beta; Magnetic Resonance Imaging; NLR Family, Pyrin Domain-Containing 3 Protein