Acrocephalosyndactylia

Synonym
Apert Syndrome
Acrocephalosyndactyly, Type II
Acrocephalosyndactyly, Type V
Dysostosis Craniofacialis with Hypertelorism
Craniofacial-Skeletal-Dermatologic Dysplasia
Apert-Crouzon Disease
Acrocephalosyndactylia
Noack Syndrome
Saethre-Chotzen Syndrome
Chotzen Syndrome
Kurczynski Casperson Syndrome
Acrocephaly, Skull Asymmetry, and Mild Syndactyly
Pfeiffer Syndrome
Syndactylic Oxycephaly
Acrocephalosyndactyly, Type III
Acrocephalosyndactyly (Apert)
Acrocephalosyndactyly III
Acrocephalosyndactyly, Type 1
Acrocephalosyndactyly, Type 3
Acrocephalosyndactyly, Type I

Excerpt	Reference
"Apert syndrome is a congenital disorder consisting primarily of deformities of the skull, hands, and feet."	( Esterly, NB; Parker, TL; Roth, JG, 1992)
"The Apert syndrome is a complex deformity."	( Flügel, M; Landsleitner, B; von Rauffer, L, 1984)
"Pfeiffer syndrome is a skeletal disorder characterized by craniosynostosis associated with foot and hand anomalies."	( Battaglia, PA; Di Rocco, C; Tartaglia, M; Valeri, S; Velardi, F, 1997)
"Pfeiffer syndrome is a classic form of craniosynostosis that is caused by a proline-->arginine substitution at amino acid 252 (Pro252Arg) in fibroblast growth factor receptor 1 (FGFR1)."	( Brodie, SG; Chen, L; Deng, CX; Li, C; Xu, X; Zhou, YX, 2000)
"Apert syndrome is a severe craniosynostosis/syndactyly disorder usually caused by specific substitutions (Ser252Trp or Pro253Arg) in FGFR2."	( Maxson, RE; Oldridge, M; Tang, Z; Wilkie, AO, 2001)
"Saethre-Chotzen syndrome is an autosomal acrocephalosyndactyly syndrome whose gene has been assigned to chromosome 7p (TWIST)."	( Calabrese, O; Clauser, L; Galiè, M; Hassanipour, A, 2000)
"The Saethre-Chotzen syndrome is characterized by premature fusion of cranial sutures resulting from mutations in Twist, a basic helix-loop-helix (bHLH) transcription factor."	( Delannoy, P; Lasmoles, F; Lomri, A; Marie, PJ; Yousfi, M, 2001)
"Apert syndrome is a monogenic human disorder in which cleft palate has been significantly correlated to the fibroblast growth factor receptor (FGFR) 2-Ser252Trp mutation."	( Britto, JA; Evans, RD; Hayward, RD; Jones, BM, 2002)
"Apert syndrome is an autosomal dominant disorder that results from gain-of-function mutations in the FGFR2 gene."	( Bieth, E; Brennetot, C; Hofman, P; Pedeutour, F; Rouzier, C; Soler, C, 2008)
"Apert syndrome is one of the most severe craniosynostosis that is mainly caused by either a Ser252Trp(S252W) or Pro253Arg(P253R) mutation in fibroblast growth factor receptor 2 (FGFR2)."	( Chen, L; Chen, Z; Deng, C; Du, X; Jin, M; Li, C; Li, F; Qi, H; Su, N; Xu, X; Xue, J; Yang, J; Yin, L; Zhao, L, 2008)
"Apert syndrome is caused by mutations in fibroblast growth factor receptor 2 (Fgfr2) and is characterized by craniosynostosis and other skeletal abnormalities."	( Elisseeff, JH; Hsu, B; Jabs, EW; Wang, Y; Yang, F; Zhang, Z, 2008)
"Apert syndrome is a rare autosomal dominant disorder characterized by craniosynostosis, craniofacial anomalies, and severe symmetrical syndactyly (cutaneous and bony fusion) of the hands and feet."	( Barnett, S; Bingham, R; Moloney, C, 2011)
"Apert syndrome is characterized by craniosynostosis and syndactyly, and is predominantly caused by mutation of either S252W or P253W in the fibroblast growth factor receptor (FGFR) 2 gene."	( Iseki, S; Kobayashi, Y; Moriyama, K; Nakamura, M; Shiga, M; Suda, N; Suzuki, H, 2012)
"Craniosynostosis in Apert syndrome is routinely treated by wide frontal and bilateral supraorbital reshaping and posterior cranial decompression."	( Dogliotti, PL; Gonzalez-Ramos, J; Nadal-López, E; Routabul, C; Zuccaro, G, 2012)
"In conclusion, Apert syndrome is more asymmetric in nature and a more severe clinical entity than Crouzon syndrome."	( Hagberg, C; Kahnberg, KE; Mohlin, B; Stavropoulos, D; Tarnow, P, 2012)
"Crouzon and Apert syndromes are frequently complicated by ocular abnormalities and patients with these syndromes often present with abnormal ocular morphology."	( Fujimoto, T; Imai, K; Maruyama, Y; Takahashi, M; Yamaguchi, K, 2013)
"Apert syndrome is a common craniosynostosis caused by gain-of-function missense mutations of fibroblast growth factor receptor 2 (FGFR2)."	( Chen, L; Deng, M; Li, X; Liu, L; Liu, R; Pu, D; Wen, X; Zhang, L; Zhou, X, 2013)
"Apert syndrome is a rare autosomal dominant disorder characterized by craniofacial abnormalities, craniosynostosis and syndactyly."	( Tsukamoto, M; Yokoyama, T, 2015)
"The Apert syndrome is a rare congenital disorder most often arising from S252W or P253R mutations in fibroblast growth factor receptor (FGFR2)."	( Cabaniss, LB; Cui, C; Huguley, S; Lu, C; MacDougall, M; Mamaeva, OA; Sarver, DM; Waite, PD, 2016)
"Apert Syndrome is a congenital condition characterised by primary craniosynostosis, midfacial malformations and complex symmetrical malformations of the hands and feet."	( Arshad, Z; McArthur, P; Mishra, A; Pettitt, DA, 2017)
"Apert syndrome is characterised by the presence of craniosynostosis, midface retrusion and syndactyly of hands and feet, thus, synonymously referred to as acrocephalosyndactyly type I."	( Farr, S; Stauffer, A, 2020)

Excerpt	Reference
"Patients with Apert syndrome have bilateral coronal craniosynostosis as one of their many distinguishing features."	( Ball, LL; Lee, SS; McIntosh, BC; Persing, JA, 2008)
"Patients with Apert syndrome have bilateral coronal craniosynostosis, along with a distinguishing feature of their many deformity, called tower skull."	( Chen, J; Cui, J; Shen, W; Weiping, S, 2015)

Excerpt	Reference
"Five patients with Pfeiffer syndrome, 1 with Crouzon, and 1 with Beare-Stevenson cutis gyrata syndrome were treated with this method."	( Fukuda, K; Kakibuchi, M; Kawai, K; Nagashima, T; Nishimoto, S; Osaki, Y; Oyama, T; Tsumano, T; Yoshimura, Y, 2008)
"Treatment of patients with severe Pfeiffer syndrome types II and III is difficult."	( Fukawa, T; Kobayashi, S; Maegawa, J; Satake, T; Yabuki, Y; Yasumura, K, 2019)
"Untreated Pfeiffer syndrome patients (n = 31) and normal control subjects (n = 43) were compared."	( Allam, O; Alonso, N; Alperovich, M; Forte, AJ; Lu, X; Park, KE; Persing, JA; Steinbacher, DM; Tonello, C; Wilson, A, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	56 (24.78)	23.3326
1990's	44 (19.47)	12.5806
2000's	60 (26.55)	18.1394
2010's	56 (24.78)	28.8240
2020's	10 (4.42)	9.53

Drug	Relationship Strength	Studies
adenine	low	1
salicylic acid	low	4
cytosine	low	2
lactic acid	low	3
iodine	low	1
4-nitrophenol	low	1
thymine	low	1
acetaminophen	low	1
caffeine	low	1
fentanyl	low	1
haloperidol	low	1
2-propanol	low	2
juglone	low	1
pd 98059	low	2
sevoflurane	low	1
sulfacetamide	low	1
thalidomide	low	3
serine	low	11
glutamine	low	1
bromodeoxyuridine	low	1
phenylalanine	low	1
histidine	low	1
tryptophan	low	10
arginine	low	13
methylprednisolone	low	1
pyrazolanthrone	low	1
thiazoles	low	1
acetylcysteine	low	1
durapatite	low	1
titanium	low	3
tricalcium phosphate	low	1
phosphotyrosine	low	1
etoposide	low	1
propiconazole	low	81
thiazolyl blue	low	1
fibrinogen	low	1
proline	low	12
atropine	low	1
sb 203580	low	2
carboplatin	low	1
inositol 3-phosphate	low	3
rocuronium	low	1
mycophenolic acid	low	1
cystine	low	1
17-ketosteroids	low	1
naphthoquinones	low	1
amphotericin b	low	1
isotretinoin	low	7
phenylephrine hydrochloride	low	17
casein kinase ii	low	1
cysteine	low	9
pregnanediol	low	1
lactacystin	low	1
ucn 1028 c	low	1
jaw	low	1
oxytetracycline, anhydrous	low	1
transforming growth factor beta	low	5
nitrophenols	low	1
guanine	low	2
eye	low	6

Protein Targets (1,163)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
RAR-related orphan receptor gamma	18	0	0	18
GLI family zinc finger 3	13	0	0	13
AR protein	20	0	0	20
aldehyde dehydrogenase 1 family, member A1	12	0	0	12
retinoic acid nuclear receptor alpha variant 1	14	0	0	14
retinoid X nuclear receptor alpha	14	0	0	14
estrogen nuclear receptor alpha	22	0	0	22
peroxisome proliferator-activated receptor delta	8	0	0	8
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	9	0	0	9
activating transcription factor 6	5	0	0	5
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
Histone H2A.x	5	0	0	5
thyroid hormone receptor beta isoform a	10	0	0	10
heat shock protein beta-1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	13	0	0	13
lamin isoform A-delta10	9	0	0	9
Voltage-dependent calcium channel gamma-2 subunit	12	0	0	12
Glutamate receptor 2	13	1	0	14
Chain A, Sulfotransferase 1A1	0	1	0	1
Chain A, Sulfotransferase 1A1	0	1	0	1
acetylcholinesterase	8	0	0	8
nuclear receptor subfamily 1, group I, member 3	11	0	0	11
progesterone receptor	9	0	0	9
estrogen-related nuclear receptor alpha	19	0	0	19
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
histone deacetylase 9 isoform 3	2	0	0	2
Endolysin	0	0	1	1
Cellular tumor antigen p53	7	0	0	7
UDP-glucuronosyltransferase 1A4	0	0	0	2
ATAD5 protein, partial	8	0	0	8
GLS protein	9	0	0	9
Microtubule-associated protein tau	9	0	0	9
Smad3	1	0	0	1
thyroid stimulating hormone receptor	8	0	0	8
EWS/FLI fusion protein	7	0	0	7
peroxisome proliferator activated receptor gamma	9	0	0	9
aryl hydrocarbon receptor	7	0	0	7
chromobox protein homolog 1	10	0	0	10
thyroid hormone receptor beta isoform 2	10	0	0	10
peripheral myelin protein 22	9	0	0	9
cytochrome P450 3A4 isoform 1	9	0	0	9
Gamma-aminobutyric acid receptor subunit pi	9	0	0	9
ATP-binding cassette sub-family C member 3	0	8	0	8
Multidrug resistance-associated protein 4	0	8	0	8
Solute carrier family 22 member 6	0	3	0	3
Carbonic anhydrase 12	0	2	0	5
UDP-glucuronosyltransferase 1A9	0	1	0	4
Bile salt export pump	0	2	0	2
Bile salt export pump	0	12	0	12
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	4	0	9
Carbonic anhydrase 2	0	4	0	9
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	2	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 3	0	2	0	5
Cytochrome P450 3A4	0	6	0	8
Cytochrome P450 2D6	0	3	0	3
Cytochrome P450 2C9	0	5	0	5
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	9	0	0	9
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	9	0	0	9
Gamma-aminobutyric acid receptor subunit gamma-2	9	0	0	9
UDP-glucuronosyltransferase 1-6	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-3	9	0	0	9
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	3
Carbonic anhydrase 4	0	2	0	5
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 6	0	2	0	5
Gamma-aminobutyric acid receptor subunit gamma-1	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-2	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-4	9	0	0	9
Gamma-aminobutyric acid receptor subunit gamma-3	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-6	9	0	0	9
Carbonic anhydrase 5A, mitochondrial	0	2	0	5
Prostaglandin G/H synthase 2	0	1	1	3
Carbonic anhydrase 7	0	2	0	5
Nuclear receptor ROR-gamma	3	0	0	3
Cytochrome P450 2J2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	9	0	0	9
Gamma-aminobutyric acid receptor subunit beta-3	9	0	0	9
Gamma-aminobutyric acid receptor subunit beta-2	9	0	0	9
Carbonic anhydrase 9	0	2	0	5
GABA theta subunit	9	0	0	9
Canalicular multispecific organic anion transporter 1	0	9	0	10
Carbonic anhydrase 15	0	2	0	5
Carbonic anhydrase 13	0	2	0	5
Gamma-aminobutyric acid receptor subunit epsilon	9	0	0	9
Carbonic anhydrase 14	0	2	0	5
Carbonic anhydrase 5B, mitochondrial	0	2	0	5
toxin B	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
dopamine D1 receptor	2	0	0	2
15-lipoxygenase, partial	6	0	0	6
pregnane X receptor	3	0	0	3
phosphopantetheinyl transferase	9	0	0	9
USP1 protein, partial	5	0	0	5
NFKB1 protein, partial	4	0	0	4
Thrombopoietin	5	0	0	5
regulator of G-protein signaling 4	7	0	0	7
glucocorticoid receptor [Homo sapiens]	17	0	0	17
farnesoid X nuclear receptor	9	0	0	9
vitamin D (1,25- dihydroxyvitamin D3) receptor	6	0	0	6
arylsulfatase A	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	19	0	0	19
Bloom syndrome protein isoform 1	9	0	0	9
D(1A) dopamine receptor	2	0	0	2
flap endonuclease 1	7	0	0	7
geminin	17	0	0	17
survival motor neuron protein isoform d	7	0	0	7
muscarinic acetylcholine receptor M1	7	0	0	7
Histone deacetylase 3	0	1	0	1
Histone deacetylase 4	0	1	0	1
Guanine nucleotide-binding protein G	3	0	0	3
Histone deacetylase 1	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Ataxin-2	9	0	0	9
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
ATP-dependent phosphofructokinase	11	0	0	11
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	10	0	0	10
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
TDP1 protein	15	0	0	15
cytochrome P450 family 3 subfamily A polypeptide 4	8	0	0	8
pregnane X nuclear receptor	12	0	0	12
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	6	0	0	6
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	1	3
ATPase family AAA domain-containing protein 5	7	0	0	7
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
Chain A, Cruzipain	3	0	0	3
interleukin 8	3	0	0	3
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	9	0	0	9
Cytochrome P450 2C19	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Aurora kinase B	0	2	1	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
thioredoxin reductase	11	0	0	11
alpha-galactosidase	1	0	0	1
cytochrome P450 2C19 precursor	3	0	0	3
DNA polymerase iota isoform a (long)	8	0	0	8
lethal factor (plasmid)	9	0	0	9
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	4	0	0	4
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	3	0	3
5-hydroxytryptamine receptor 4	0	4	0	4
Muscarinic acetylcholine receptor M2	0	4	1	8
Muscarinic acetylcholine receptor M4	0	3	1	6
Muscarinic acetylcholine receptor M1	0	4	1	7
Muscarinic acetylcholine receptor M3	0	4	1	7
Muscarinic acetylcholine receptor M4	0	4	1	7
Muscarinic acetylcholine receptor M5	0	4	1	7
Muscarinic acetylcholine receptor M5	0	4	1	7
Muscarinic acetylcholine receptor M2	0	4	1	8
Muscarinic acetylcholine receptor M1	0	6	1	10
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	3	1	6
Alpha-1D adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 2C	0	4	0	4
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	6	0	0	8
5-hydroxytryptamine receptor 7	0	2	0	2
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	3
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
IDH1	4	0	0	4
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
cellular tumor antigen p53 isoform a	4	0	0	4
Nuclear hormone receptor family member daf-12	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
oxysterols receptor LXR-beta isoform 1	0	0	1	1
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
Thymidine kinase, cytosolic	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Spike glycoprotein	4	0	0	4
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
thyroid stimulating hormone receptor	8	0	0	8
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
nuclear receptor ROR-gamma isoform 1	6	0	0	6
DNA polymerase kappa isoform 1	7	0	0	7
Potassium channel subfamily K member 2	0	1	1	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Cholinesterase	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Adenosine receptor A3	0	3	0	3
Replicase polyprotein 1ab	0	1	0	1
Amine oxidase [flavin-containing] A	0	3	0	3
Acetylcholinesterase	0	2	0	2
Adenosine receptor A1	0	3	0	6
Amine oxidase [flavin-containing] B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	4	1	6
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	3	1	6
Adenosine receptor A2a	0	2	0	6
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	1	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	1	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	1	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
estrogen receptor 2 (ER beta)	5	0	0	5
G	3	0	0	3
cytochrome P450 2D6	6	0	0	6
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Interferon beta	4	0	0	4
HLA class I histocompatibility antigen, B alpha chain	3	0	0	3
Inositol hexakisphosphate kinase 1	3	0	0	3
cytochrome P450 2C9, partial	3	0	0	3
Chain A, Protein kinase CK2, alpha Subunit	0	1	0	1
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT	0	1	0	1
Chain A, Protein Kinase Ck2, Alpha Subunit	0	1	0	1
Chain A, Ferritin light chain	4	0	0	4
endonuclease IV	2	0	0	2
Parkin	4	0	0	4
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
peripheral myelin protein 22 isoform 1	7	0	0	7
mitogen-activated protein kinase 1	5	0	0	5
ras-related protein Rab-9A	2	0	0	2
Serine/threonine-protein kinase Sgk1	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	1	2
Casein kinase II subunit alpha	0	1	0	1
Casein kinase II subunit alpha'	0	2	1	3
Cyclin-A2	0	1	0	1
Cyclin-dependent kinase 2	0	1	2	3
D(1A) dopamine receptor	2	1	0	3
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	2	1	3
Cyclin-A1	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	3	1	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	1	2
Ribosomal protein S6 kinase alpha-1	0	1	1	2
Casein kinase II subunit alpha 3	0	2	0	2
Single-stranded DNA cytosine deaminase	2	0	0	2
Deoxycytidine kinase	0	0	0	1
glp-1 receptor, partial	5	0	0	5
SMAD family member 2	3	0	0	3
SMAD family member 3	3	0	0	3
caspase 7, apoptosis-related cysteine protease	2	0	0	2
67.9K protein	5	0	0	5
caspase-3	2	0	0	2
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Prothrombin	0	0	0	1
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
ATP-dependent translocase ABCB1	0	5	0	7
DNA topoisomerase 1	0	2	0	4
DNA topoisomerase 2-alpha	0	1	1	7
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	2	0	6
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	5
Glutamate receptor ionotropic, NMDA 2B	0	1	0	5
Glutamate receptor ionotropic, NMDA 2C	0	1	0	5
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	1	8
Glutamate receptor ionotropic, NMDA 2D	0	1	0	5
Tubulin beta-2B chain	0	1	0	1
Integrase	0	2	0	2
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	5
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	1	0	5
Luciferase	6	0	0	6
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
D(2) dopamine receptor	0	3	1	6
D(4) dopamine receptor	0	3	1	6
Delta-type opioid receptor	0	3	0	3
Delta-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	3	1	4
Kappa-type opioid receptor	0	2	0	2
Histamine H1 receptor	0	3	0	3
Mu-type opioid receptor	0	4	2	6
D(3) dopamine receptor	0	3	1	6
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	3	0	3
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	3	0	3
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	3	0	3
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	4
Amino acid transporter	0	3	0	3
Purine nucleoside phosphorylase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Fumarate hydratase	2	0	0	2
nonstructural protein 1	5	0	0	5
polyprotein	2	0	0	2
glucocerebrosidase	2	0	0	2
Adenylate cyclase type 1	0	1	0	1
cytochrome P450 2D6 isoform 1	4	0	0	4
cytochrome P450 2C9 precursor	4	0	0	4
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Cocaine esterase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Albumin	0	0	1	1
Major prion protein	0	0	1	1
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Beta-2 adrenergic receptor	0	2	0	2
Angiotensin-converting enzyme	0	1	0	1
Integrin alpha-4	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-1B adrenergic receptor	0	5	0	5
Carbonyl reductase [NADPH] 1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
Alpha-2B adrenergic receptor	0	4	0	4
Beta-1 adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	2	0	2
D	0	2	0	2
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Alpha-2B adrenergic receptor	0	1	0	1
D(2) dopamine receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	3
D(1B) dopamine receptor	0	2	0	3
Adenylate cyclase type 3	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	3	0	3
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Histamine H2 receptor	0	2	0	2
D(1B) dopamine receptor	0	2	0	2
Beta-3 adrenergic receptor	0	1	0	1
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
D(4) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Histamine H1 receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	1	0	1
C-8 sterol isomerase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Adenylate cyclase type 8	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	5	0	5
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
D(2) dopamine receptor	0	2	0	2
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Protease	0	2	0	2
Adenylyl cyclase 7	0	1	0	1
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Plasma kallikrein	0	0	0	3
Histidine-binding periplasmic protein	0	0	1	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Large neutral amino acids transporter small subunit 1	0	3	0	4
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase 13	0	0	0	2
Carbonic anhydrase 4	0	0	0	1
Caspase-7	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
caspase-3	1	0	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
DNA polymerase eta isoform 1	3	0	0	3
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	1	0	1
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	2	1	3
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Mitogen-activated protein kinase 14	0	4	2	6
Rap guanine nucleotide exchange factor 4	1	0	0	1
Olfactory receptor 51E2	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ	0	1	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
caspase-1 isoform alpha precursor	2	0	0	2
Aurora kinase A	0	1	2	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Integrin beta-3	3	0	0	3
Integrin alpha-IIb	3	0	0	3
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Glutamate receptor 1	1	1	0	2
Glutamate receptor 3	1	1	0	2
Glutamate receptor 4	1	1	0	2
Platelet-activating factor receptor	1	0	0	1
Dual specificity protein phosphatase 1	0	1	0	1
M-phase inducer phosphatase 2	0	1	0	1
Caspase-7	2	0	0	2
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Dual specificity protein phosphatase 6	0	1	0	1
5-lipoxygenase	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
Proteasome subunit beta type-1	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
PPM1D protein	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
muscleblind-like protein 1 isoform 1	4	0	0	4
Glucocorticoid receptor	0	2	0	2
Glycine receptor subunit alpha-1	0	2	0	2
Androgen receptor	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	0	2
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Alpha-synuclein	1	1	0	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain A, Beta-lactamase	2	0	0	2
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
thioredoxin glutathione reductase	2	0	0	2
apical membrane antigen 1, AMA1	1	0	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
transcriptional regulator ERG isoform 3	1	0	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Rap guanine nucleotide exchange factor 3	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
phosphoglycerate kinase	1	0	0	1
pyruvate kinase	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	2	1	3
Luciferin 4-monooxygenase	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Mitogen-activated protein kinase 3	0	0	1	2
Dual specificity mitogen-activated protein kinase kinase 2	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	2	0	2
GALC protein	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Tyrosine-protein kinase Lck	0	1	1	3
Proto-oncogene tyrosine-protein kinase Src	0	1	1	3
Growth factor receptor-bound protein 2	0	0	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	0	0	1
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
heat shock protein 90, putative	0	0	0	1
Chain A, Mitogen-activated protein kinase 10	0	1	0	1
Chain A, Mitogen-activated protein kinase 10	0	1	0	1
Chain A, Mitogen-activated protein kinase 10	0	1	0	1
acid sphingomyelinase	1	0	0	1
RGS12	1	0	0	1
TPA: protein transporter TIM10	0	1	0	1
TPA: protein transporter TIM23	0	1	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
polyadenylate-binding protein 1	0	1	0	1
Serine/threonine-protein kinase PLK4	0	0	2	2
Cyclin-G-associated kinase	0	1	2	3
3-phosphoinositide-dependent protein kinase 1	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	1	1	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Interferon-induced, double-stranded RNA-activated protein kinase	0	1	1	2
Ephrin type-A receptor 3	0	0	2	2
Dual specificity protein kinase TTK	0	1	2	3
Mitogen-activated protein kinase 8	0	1	2	3
Mitogen-activated protein kinase 9	0	2	2	4
Casein kinase I isoform epsilon	0	1	2	3
Dual specificity protein kinase CLK2	0	0	2	2
Tyrosine-protein kinase JAK3	0	1	1	2
Mitogen-activated protein kinase 12	0	1	3	4
Mitogen-activated protein kinase 10	0	3	2	5
Cyclin-dependent kinase 16	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Ribosomal protein S6 kinase alpha-2	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1G	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Serine/threonine-protein kinase 3	0	0	1	1
BMP-2-inducible protein kinase	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
Death-associated protein kinase 2	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	1	2	3
Aurora kinase C	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	2	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	2
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Albumin	0	1	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	2	1	3
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	2
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	2
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Erk2	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	1	1
Serine/threonine-protein kinase 25	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Citron Rho-interacting kinase	0	1	1	2
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Mitogen-activated protein kinase 13	0	1	2	3
Mitogen-activated protein kinase 2	0	1	0	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	1	1	2
NUAK family SNF1-like kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Serine/threonine-protein kinase 17B	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	1	1	2
Cyclin-dependent kinase 14	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
Tyrosine-protein kinase ABL1	0	0	1	1
Epidermal growth factor receptor	0	1	1	2
Receptor tyrosine-protein kinase erbB-2	0	1	1	2
High affinity nerve growth factor receptor	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Myeloperoxidase	0	2	0	2
Protein kinase C beta type	0	1	0	1
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Fyn	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Neutrophil elastase	0	1	0	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
Tyrosinase	0	1	0	1
Fibroblast growth factor receptor 1	0	0	1	1
Cholesteryl ester transfer protein	0	1	0	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Serine/threonine-protein kinase B-raf	0	1	1	2
Platelet-derived growth factor receptor alpha	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	1	2
Vascular endothelial growth factor receptor 1	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	1	0	1
cAMP-dependent protein kinase catalytic subunit beta	0	1	1	2
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Thromboxane-A synthase	0	1	0	1
Protein kinase C eta type	0	1	1	2
Activin receptor type-2A	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Ephrin type-B receptor 2	0	1	1	2
Leukocyte tyrosine kinase receptor	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	0	1	1
Vascular endothelial growth factor receptor 2	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	1	2
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	1	1	2
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Protein kinase C iota type	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	1	1
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
Tyrosine-protein kinase SYK	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Mitogen-activated protein kinase 14	0	1	1	2
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	1	1	2
MAP kinase-activated protein kinase 2	0	0	1	1
Cyclin-dependent kinase 8	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Tyrosine-protein kinase Blk	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
Death-associated protein kinase 1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-B receptor 1	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Tubulin alpha-1A chain	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
Protein kinase C epsilon type	0	1	1	2
Angiopoietin-1 receptor	0	1	1	2
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Protein kinase C theta type	0	1	1	2
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	1	2
Tyrosine-protein kinase BTK	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	1	1	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase PAK 1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Serine/threonine-protein kinase D1	0	1	1	2
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	1	2	3
Serine/threonine-protein kinase STK11	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
P2X purinoceptor 7	0	1	0	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
SRSF protein kinase 1	0	0	1	1
P2X purinoceptor 7	0	1	0	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	1	1	2
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Serine/threonine-protein kinase PLK2	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Serine/threonine-protein kinase NLK	0	1	1	2
Phosphatidylinositol 4-kinase beta	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
ALK tyrosine kinase receptor	0	0	1	1
SRSF protein kinase 3	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Acetylcholinesterase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Cholinesterase	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Cereblon isoform 4	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Thymidine phosphorylase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
M-phase phosphoprotein 8	1	0	0	1
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Cadherin-1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Adenomatous polyposis coli protein	0	1	0	1
Catenin beta-1	0	2	0	2
Inositol monophosphatase 1	1	0	0	1
Transcription factor 7-like 2	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(20)

Research Excerpts

Overview

Context

Treatment

Research

Studies (226)

Protein Targets (1,163)

Acrocephalosyndactylia

Synonyms(20)

Research Excerpts

Overview

Context

Treatment

Research

Studies (226)

Drugs Studied (72)

Protein Targets (1,163)