Page last updated: 2024-09-27

Polydipsia

Excessive thirst manifested by excessive fluid intake. It is characteristic of many diseases such as DIABETES MELLITUS; DIABETES INSIPIDUS; and NEPHROGENIC DIABETES INSIPIDUS. The condition may be psychogenic in origin.

Synonyms(1)

Synonym
Polydipsia

Research Excerpts

Overview

ExcerptReference
"Polydipsia is a serious condition often seen among patients with schizophrenia (SCZ)."( Chen, HI; Nakamura, J; Shinkai, T; Utsunomiya, K; Yamada, K, 2014)
"Polydipsia is induced preclinically by intermittent reward, leading rodents to ingest large amounts of fluids."( Adriani, W; Annunzi, E; Curcio, G; D'Addario, C; Festucci, F; Pepe, M, 2022)

Research

Studies (109)

TimeframeStudies, This Condition (%)All Conditions %
pre-199014 (12.84)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's73 (66.97)28.8240
2020's22 (20.18)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low10
3-hydroxybutyric acid0low10
histamine0low10
urea0low10
phenytoin0low10
chlorpromazine0low10
citalopram0low10
amphetamine0low30
diphenhydramine0low10
fluoxetine0low10
furosemide0low10
haloperidol0low10
methylphenidate0low20
mirtazapine0low10
phenylbutazone0low10
propantheline0low10
temozolomide0low10
corticosterone0low20
prednisolone0low10
alloxan0low10
thyroxine0low30
dextroamphetamine0low30
prednisone0low30
phenylephrine0low10
methionine0low10
desoxycorticosterone0low30
cordycepin0low10
tryptophan0low20
arginine0low10
triamcinolone acetonide0low10
xylitol0low10
yohimbine0low10
oxazoles0low10
thiazoles0low10
limestone0low10
canrenone0low10
s,n,n'-tripropylthiocarbamate0low10
ng-nitroarginine methyl ester0low10
fomesafen0low10
quinpirole0low10
fosphenytoin0low10
duloxetine hydrochloride0low10
zoledronic acid0low10
rosiglitazone0low10
cobalt0low10
oxytocin0low10
nitroarginine0low10
inositol 3-phosphate0low10
gw 39650low10
arginine vasopressin0low90
17-ketosteroids0low10
sb 4081240low10
topiramate0low10
deamino arginine vasopressin0low90
mdl 1009070low10
levorphanol0low10
fumarates0low10
aliskiren0low10
dizocilpine maleate0low20
microcystin rr0low10
lisdexamfetamine dimesylate0low10
pituitrin0low170
c-peptide0low10
minocycline0low10
mobic0low10
clozapine0low10
dacarbazine0low10
olanzapine0low10

Protein Targets (812)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Protein skinhead-10101
Monocarboxylate transporter 20101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Fumarate hydratase7007
polyprotein7007
Pepsin A0101
Renin0101
Renin-1 0101
Renin 0101
Cytochrome P450 3A406110
Cytochrome P450 2C9 012114
Cathepsin D 0101
Renin0101
Renin 0101
Protease 0101
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, 2-oxoglutarate Oxygenase6006
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Xcogt0011
Chain A, Xcogt0011
Chain A, Xcogt0011
phosphopantetheinyl transferase100010
USP1 protein, partial8008
TDP1 protein230023
Microtubule-associated protein tau9009
Bloom syndrome protein isoform 17007
vitamin D3 receptor isoform VDRA9009
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
Disintegrin and metalloproteinase domain-containing protein 172002
Solute carrier family 22 member 30303
5-hydroxytryptamine receptor 2C012214
Phenylethanolamine N-methyltransferase0303
Cytochrome P450 2A60101
Substance-P receptor0101
5-hydroxytryptamine receptor 2A013215
5-hydroxytryptamine receptor 1A014216
Cytochrome P450 2A50101
Sodium-dependent dopamine transporter012214
5-hydroxytryptamine receptor 1B09211
5-hydroxytryptamine receptor 1D0527
5-hydroxytryptamine receptor 1F0527
5-hydroxytryptamine receptor 2B011314
5-hydroxytryptamine receptor 60123
5-hydroxytryptamine receptor 7 0426
5-hydroxytryptamine receptor 5A0123
5-hydroxytryptamine receptor 5B0123
5-hydroxytryptamine receptor 3A0325
Sigma non-opioid intracellular receptor 10404
5-hydroxytryptamine receptor 4 0123
Beta-2 adrenergic receptor0202
5-hydroxytryptamine receptor 3B0325
Sigma non-opioid intracellular receptor 10718
glucocerebrosidase3003
DNA polymerase kappa isoform 16006
histone acetyltransferase KAT2A isoform 16006
Atrial natriuretic peptide receptor 30202
Type-1A angiotensin II receptor 0426
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0404
Type-1 angiotensin II receptor0439
Type-2 angiotensin II receptor0505
Type-2 angiotensin II receptor0303
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE9009
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase160016
NFKB1 protein, partial7007
GLS protein110011
thyroid stimulating hormone receptor110011
alpha-galactosidase2002
euchromatic histone-lysine N-methyltransferase 2210021
cytochrome P450 2C19 precursor5005
chromobox protein homolog 1100010
flap endonuclease 15005
DNA polymerase iota isoform a (long)7007
muscarinic acetylcholine receptor M18008
lethal factor (plasmid)7007
Nitric oxide synthase, endothelial0305
Nitric oxide synthase, brain0304
Nitric oxide synthase, brain 0203
Nitric oxide synthase, inducible0304
Nitric oxide synthase, inducible0316
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase7007
peripheral myelin protein 226006
ATP-binding cassette sub-family C member 3018018
Multidrug resistance-associated protein 4018018
Bile salt export pump024024
Translocator protein0011
Vasopressin V2 receptor0438
Oxytocin receptor0347
Vasopressin V1a receptor0123
Vasopressin V1a receptor0437
Vasopressin V1b receptor0336
Vasopressin V2 receptor0011
Vasopressin V1b receptor0214
Translocator protein0203
Oxytocin receptor0202
Vasopressin V2 receptor 0325
Canalicular multispecific organic anion transporter 1016016
glp-1 receptor, partial5005
RAR-related orphan receptor gamma150015
SMAD family member 24004
SMAD family member 34004
GLI family zinc finger 3200020
AR protein210021
nuclear receptor subfamily 1, group I, member 3150015
progesterone receptor130013
cytochrome P450 family 3 subfamily A polypeptide 4160016
glucocorticoid receptor [Homo sapiens]170017
retinoic acid nuclear receptor alpha variant 1180018
estrogen-related nuclear receptor alpha230023
estrogen nuclear receptor alpha280028
G100010
peroxisome proliferator activated receptor gamma140014
vitamin D (1,25- dihydroxyvitamin D3) receptor130013
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a110011
thyroid hormone receptor beta isoform 2190019
nuclear factor erythroid 2-related factor 2 isoform 1170017
Vpr1001
muscleblind-like protein 1 isoform 13003
Voltage-dependent calcium channel gamma-2 subunit8008
Interferon beta130013
HLA class I histocompatibility antigen, B alpha chain 100010
Glutamate receptor 28008
Inositol hexakisphosphate kinase 1100010
cytochrome P450 2C9, partial100010
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Proteasome subunit beta type-110001
acetylcholinesterase3003
ATAD5 protein, partial5005
Thrombopoietin4004
Smad32002
caspase 7, apoptosis-related cysteine protease6006
estrogen receptor 2 (ER beta)7007
NADPH oxidase 10101
retinoid X nuclear receptor alpha100010
farnesoid X nuclear receptor6006
pregnane X nuclear receptor170017
cytochrome P450 2D69009
67.9K protein1001
peroxisome proliferator-activated receptor delta110011
Snq2p0001
caspase-36006
IDH16006
Adenylate cyclase type 1 0404
thyroid stimulating hormone receptor5005
v-jun sarcoma virus 17 oncogene homolog (avian)130013
Histone H2A.x7007
Caspase-72002
Spike glycoprotein0112
Replicase polyprotein 1ab0112
cytochrome P450 2D6 isoform 17007
cellular tumor antigen p53 isoform a1001
D(1A) dopamine receptor8008
potassium voltage-gated channel subfamily H member 2 isoform d9009
caspase-32002
histone deacetylase 9 isoform 31001
heat shock protein beta-14004
mitogen-activated protein kinase 17007
atrial natriuretic peptide receptor 2 precursor3003
ras-related protein Rab-9A3003
serine/threonine-protein kinase mTOR isoform 15005
geminin170017
survival motor neuron protein isoform d8008
cytochrome P450 3A4 isoform 19009
M-phase phosphoprotein 84004
lamin isoform A-delta10170017
Gamma-aminobutyric acid receptor subunit pi92011
Proteasome subunit alpha type-70001
Solute carrier family 22 member 1 0607
Polyunsaturated fatty acid lipoxygenase ALOX15B4004
Transmembrane protease serine 20112
Glutamate receptor ionotropic, NMDA 2D0213
Transient receptor potential cation channel subfamily V member 10202
Glutamate receptor ionotropic, NMDA 3B0213
Voltage-dependent L-type calcium channel subunit alpha-1F0404
Bile salt export pump0505
5-hydroxytryptamine receptor 4014014
Potassium channel subfamily K member 20303
Epidermal growth factor receptor0101
Albumin0224
Albumin0044
Major prion protein0022
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20101
Cellular tumor antigen p53120012
Major prion protein0011
Integrin beta-31001
Cytochrome P450 1A20011
Tyrosine-protein kinase Fyn0101
Procathepsin L0112
Aldo-keto reductase family 1 member B1012012
Muscarinic acetylcholine receptor M20819
Muscarinic acetylcholine receptor M409110
ATP-dependent translocase ABCB10409
Muscarinic acetylcholine receptor M10516
Muscarinic acetylcholine receptor M30516
Muscarinic acetylcholine receptor M40516
Integrin alpha-IIb1001
5-hydroxytryptamine receptor 1A08311
Muscarinic acetylcholine receptor M50516
Muscarinic acetylcholine receptor M5012012
Alpha-2A adrenergic receptor014216
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0213
Cys-loop ligand-gated ion channel0101
Calmodulin-10314
Replicase polyprotein 1ab0224
Cytochrome P450 2D60416
Muscarinic acetylcholine receptor M20516
Muscarinic acetylcholine receptor M1011213
Polyunsaturated fatty acid lipoxygenase ALOX150202
Angiotensin-converting enzyme012012
D(2) dopamine receptor013221
Gamma-aminobutyric acid receptor subunit beta-192011
Alpha-1B adrenergic receptor015217
Sphingomyelin phosphodiesterase0101
Alpha-2B adrenergic receptor014014
Gamma-aminobutyric acid receptor subunit delta92011
Gamma-aminobutyric acid receptor subunit gamma-292011
Alpha-2C adrenergic receptor013114
D010011
D(3) dopamine receptor09112
Alpha-2B adrenergic receptor010212
Gamma-aminobutyric acid receptor subunit alpha-592011
Gamma-aminobutyric acid receptor subunit alpha-392011
D(2) dopamine receptor0606
Muscarinic acetylcholine receptor M3011112
Proteasome subunit beta type-10001
Substance-K receptor0202
D(1A) dopamine receptor010013
D(4) dopamine receptor010218
D(1B) dopamine receptor0407
Adenylate cyclase type 30404
Alpha-2C adrenergic receptor010212
UDP-glucuronosyltransferase 1A40004
Alpha-2A adrenergic receptor010212
Gamma-aminobutyric acid receptor subunit gamma-192011
Gamma-aminobutyric acid receptor subunit alpha-292011
Alpha-1D adrenergic receptor015217
Sodium-dependent noradrenaline transporter 017320
Histamine H2 receptor0729
Alpha-1D adrenergic receptor012012
D(1B) dopamine receptor0707
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20404
Adenylate cyclase type 40404
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
5-hydroxytryptamine receptor 2A016119
5-hydroxytryptamine receptor 2C016117
Gamma-aminobutyric acid receptor subunit alpha-492011
Gamma-aminobutyric acid receptor subunit gamma-392011
Trypanothione reductase0202
Gamma-aminobutyric acid receptor subunit alpha-692011
D(4) dopamine receptor0808
Histamine H1 receptor0449
Sodium-dependent serotonin transporter016420
Melanocortin receptor 40202
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 70505
Histamine H1 receptor016523
Mu-type opioid receptor0617
Glutamate receptor ionotropic, NMDA 1 0417
D(3) dopamine receptor010217
Sodium channel protein type 1 subunit alpha0303
Sodium channel protein type 4 subunit alpha0304
Adenylate cyclase type 80404
Proteasome subunit beta type-100001
Delta-type opioid receptor0404
Kappa-type opioid receptor0404
5-hydroxytryptamine receptor 2B016117
Melanocortin receptor 30202
Alpha-1A adrenergic receptor015217
Histamine H2 receptor80111
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
D(1A) dopamine receptor3205
5-hydroxytryptamine receptor 6011012
5-hydroxytryptamine receptor 70303
Cytochrome P450 2J20809
Gastrin/cholecystokinin type B receptor0303
Spike glycoprotein101112
Proteasome subunit alpha type-60012
D(2) dopamine receptor014219
Calmodulin 0123
Gamma-aminobutyric acid receptor subunit alpha-192011
Gamma-aminobutyric acid receptor subunit beta-392011
Gamma-aminobutyric acid receptor subunit beta-292011
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0406
Glutamate receptor ionotropic, NMDA 2B0507
Glutamate receptor ionotropic, NMDA 2C0406
Sodium channel protein type 7 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0404
Sodium-dependent dopamine transporter 010212
Adenylate cyclase type 60404
Adenylate cyclase type 50404
Glutamate receptor ionotropic, NMDA 10213
Aldehyde oxidase0202
Potassium voltage-gated channel subfamily H member 2018018
Glutamate receptor ionotropic, NMDA 2A0213
Glutamate receptor ionotropic, NMDA 2B0213
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Sodium channel protein type 5 subunit alpha0404
Glutamate receptor ionotropic, NMDA 2C0213
Sodium channel protein type 9 subunit alpha0303
Glutamate receptor ionotropic, NMDA 2D0406
Nuclear receptor subfamily 3 group C member 3 011011
Adenylyl cyclase 7 0404
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0213
Glutamate receptor ionotropic, NMDA 3B0406
GABA theta subunit92011
D0505
Sodium channel protein type 2 subunit alpha0303
Proteasome subunit beta type-70001
Ataxin-2110011
Sigma non-opioid intracellular receptor 1010010
Angiotensin-converting enzyme 2 0112
Gamma-aminobutyric acid receptor subunit epsilon92011
Sodium channel protein type 3 subunit alpha0303
Glutamate receptor ionotropic, NMDA 3A0406
Sodium channel protein type 11 subunit alpha0202
Sodium channel protein type 8 subunit alpha0202
Histamine H3 receptor0426
Sodium channel protein type 10 subunit alpha0202
aldehyde dehydrogenase 1 family, member A1110011
EWS/FLI fusion protein150015
NPC intracellular cholesterol transporter 1 precursor2002
Sodium-dependent noradrenaline transporter0202
Tryptophan 5-hydroxylase 10101
Aldo-keto reductase family 1 member B10202
Acetylcholinesterase0303
Aromatase0101
Sodium-dependent serotonin transporter0617
Sigma intracellular receptor 20303
Sodium-dependent serotonin transporter0202
Sodium-dependent dopamine transporter0202
Transporter0707
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, JmjC domain-containing histone demethylation protein 3A2002
5-hydroxytryptamine receptor 3E0202
Luciferase6006
hypoxia-inducible factor 1 alpha subunit6006
Beta-1 adrenergic receptor 0101
bromodomain adjacent to zinc finger domain 2B3003
peripheral myelin protein 22 isoform 15005
cytochrome P450 2C9 precursor6006
DNA polymerase beta1001
nuclear receptor ROR-gamma isoform 18008
short transient receptor potential channel 6 isoform 10011
transient receptor potential cation channel subfamily V member 12002
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 3B0202
Beta-2 adrenergic receptor0404
Beta-1 adrenergic receptor0303
Endothelin receptor type B0101
5-hydroxytryptamine receptor 3A0202
Endothelin receptor type B0101
Adenosine receptor A10405
Beta-3 adrenergic receptor0202
Histamine H1 receptor0617
Cytochrome P450 2C190203
5-hydroxytryptamine receptor 2C 0202
Alpha-1A adrenergic receptor0617
5-hydroxytryptamine receptor 2A0202
Alpha-1B adrenergic receptor0516
5-hydroxytryptamine receptor 3A0303
5-hydroxytryptamine receptor 5A0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0202
D(2) dopamine receptor0202
D(3) dopamine receptor0202
D(2) dopamine receptor0101
Inositol monophosphatase 15005
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 40202
Transporter0404
Cholecystokinin receptor type A0202
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 3D0202
5-hydroxytryptamine receptor 3C0202
ATPase family AAA domain-containing protein 56006
Histamine H4 receptor0336
PINK11001
Parkin2002
heat shock protein 900011
TPA: protein transporter TIM230101
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Sterol 14-alpha demethylase0101
RNA-directed RNA polymerase 0112
Carnitine O-palmitoyltransferase 1, muscle isoform0101
pregnane X receptor3003
GALC protein3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
nonstructural protein 13003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
thyroid hormone receptor beta isoform a4004
nuclear factor erythroid 2-related factor 2 isoform 25005
Solute carrier family 22 member 20102
Solute carrier family 22 member 30203
Sex hormone-binding globulin0022
Corticosteroid-binding globulin0303
Mineralocorticoid receptor 0224
Androgen receptor0202
C-8 sterol isomerase0202
Solute carrier organic anion transporter family member 1A10101
Nuclear receptor ROR-gamma2002
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0202
Solute carrier family 22 member 10405
Solute carrier family 22 member 20506
interleukin 81001
activating transcription factor 61001
Matrix metalloproteinase-90303
Isocitrate lyase0101
nuclear receptor subfamily 1, group I, member 23003
TAR DNA-binding protein 436006
Amine oxidase [flavin-containing] B0202
Amine oxidase [flavin-containing] A0202
Amine oxidase [flavin-containing] B0303
Amine oxidase [flavin-containing] B0101
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
regulator of G-protein signaling 48008
huntingtin isoform 22002
Histamine N-methyltransferase0001
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Histamine H3 receptor0102
aryl hydrocarbon receptor9009
importin subunit beta-1 isoform 12002
snurportin-12002
GTP-binding nuclear protein Ran isoform 11001
Alpha-synuclein1001
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Sodium channel protein type 1 subunit alpha0202
Cytochrome P450 2C80202
Dipeptidyl peptidase 40101
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit gamma-20202
Acetylcholinesterase0101
Prostaglandin G/H synthase 10303
Potassium voltage-gated channel subfamily C member 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Gamma-aminobutyric acid receptor subunit beta-30202
Gamma-aminobutyric acid receptor subunit alpha-50202
Gamma-aminobutyric acid receptor subunit alpha-30202
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit epsilon0202
Gastrin/cholecystokinin type B receptor 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Gamma-aminobutyric acid receptor subunit alpha-60202
Cytochrome P450 1B10101
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit theta0202
thyrotropin-releasing hormone receptor2002
Solute carrier family 22 member 60202
Carbonic anhydrase 120509
Carbonic anhydrase 107011
Carbonic anhydrase 208114
Carbonic anhydrase 30305
Glucose-6-phosphate 1-dehydrogenase0303
Carbonic anhydrase 40307
Carbonic anhydrase 60307
Serum paraoxonase/arylesterase 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase 5A, mitochondrial0318
Carbonic anhydrase 70307
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
Sodium/bile acid cotransporter0202
Carbonic anhydrase 90509
Multidrug and toxin extrusion protein 10202
Carbonic anhydrase 130307
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10404
Carbonic anhydrase 140408
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Carbonic anhydrase 5B, mitochondrial0307
Chain A, Cruzipain3003
tyrosine-protein kinase Yes1001
Nuclear receptor subfamily 1 group I member 20112
Plasma kallikrein0013
Retinoic acid receptor RXR-alpha0033
Alpha-glucosidase MAL320101
Oxysterols receptor LXR-beta0213
Oxysterols receptor LXR-alpha0123
15-lipoxygenase, partial2002
arylsulfatase A6006
Cocaine esterase0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
UDP-glucuronosyltransferase 1A90102
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10101
Integrin alpha-40101
Carbonyl reductase [NADPH] 10001
UDP-glucuronosyltransferase 2B70102
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Kappa-type opioid receptor0101
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2A0213
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20101
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
Protease 0202
Transient receptor potential cation channel subfamily V member 40101
Transient receptor potential cation channel subfamily V member 20101
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
Chain A, Beta-lactamase3003
aryl hydrocarbon receptor nuclear translocator0001
apical membrane antigen 1, AMA12002
transforming acidic coiled-coil-containing protein 30001
Macrophage migration inhibitory factor0202
5-hydroxytryptamine receptor 1D0001
Adenosine receptor A2a0203
Metabotropic glutamate receptor 50112
Carbonic anhydrase0103
Carbonic anhydrase0104
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 0104
Carbonic anhydrase-like protein, putative0002
Carbonic anhydrase0104
Carbonic anhydrase0104
Carbonic anhydrase 0104
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130102
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 40203
Carbonic anhydrase 150204
Carboxylic ester hydrolase 0001
Acetylcholinesterase0101
Sigma non-opioid intracellular receptor 10101
Delta-type opioid receptor0102
Kappa-type opioid receptor0101
Mu-type opioid receptor0101
Mu-type opioid receptor0415
Mas-related G-protein coupled receptor member X20011
Neprilysin0101
Angiotensin-converting enzyme 0101
Thromboxane A2 receptor 0102
Type-1 angiotensin II receptor0112
Squalene synthase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Platelet glycoprotein VI0113
Solute carrier organic anion transporter family member 1B30202
Type-1 angiotensin II receptor0112
Solute carrier organic anion transporter family member 1B10203
Potassium voltage-gated channel subfamily KQT member 10101
Cysteinyl leukotriene receptor 10101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Large neutral amino acids transporter small subunit 10202
Stromelysin-10213
Matrilysin0101
Multidrug transporter MdfA0101
Protein mono-ADP-ribosyltransferase PARP150101
Protein-arginine deiminase type-40202
Angiotensin-converting enzyme0101
Glutathione reductase, mitochondrial0101
Prostaglandin G/H synthase 20404
Prostaglandin G/H synthase 20101
Neutrophil elastase0101
Nitric oxide synthase, endothelial0303
Collagenase 30101
prostaglandin E2 receptor EP2 subtype0001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Nitric oxide synthase, inducible0101
Nitric oxide synthase, brain0101
lysosomal alpha-glucosidase preproprotein1001
FAD-linked sulfhydryl oxidase ALR0001
Sodium channel protein type 2 subunit alpha0303
Sodium channel protein type 3 subunit alpha0101
Oxytocin receptor0011
Estrogen receptor 10101
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
fMet-Leu-Phe receptor0101
neuropeptide S receptor isoform A1001
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0202
Cyclooxygenase-2 0101
Solute carrier family 22 member 80202
dopamine D1 receptor2002
Alpha-1B adrenergic receptor 0011
Beta-2 adrenergic receptor0112
Beta-1 adrenergic receptor0011
Beta-3 adrenergic receptor0011
POU domain, class 2, transcription factor 10001
Alpha-1A adrenergic receptor0213
Alpha-1B adrenergic receptor0101
Alpha-2B adrenergic receptor0102
Alpha-2C adrenergic receptor0102
Alpha-2A adrenergic receptor0102
Gamma-aminobutyric acid 0101
endonuclease IV1001
atrial natriuretic peptide receptor 1 precursor1001
transcriptional regulator ERG isoform 31001
Dihydrofolate reductase 0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor06213
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10606
Androgen receptor0202
Glutamine synthetase0011
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nociceptin receptor0011
Estrogen receptor beta0202
thioredoxin glutathione reductase2002
interferon gamma precursor0001
Dipeptidyl peptidase 40011
Dipeptidyl peptidase 40011
Adenosine receptor A2a0011
Metabotropic glutamate receptor 50011
CDGSH iron-sulfur domain-containing protein 10101
Free fatty acid receptor 10011
Tyrosine-protein phosphatase non-receptor type 10204
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Cytochrome P450 3A50011
Amine oxidase [flavin-containing] A 0101
Catechol O-methyltransferase0011
Peroxisome proliferator-activated receptor alpha0112
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Thromboxane-A synthase 0101
Peroxisome proliferator-activated receptor gamma0247
Peroxisome proliferator-activated receptor gamma0011
C-C chemokine receptor type 20101
Cannabinoid receptor 20011
Carnitine O-palmitoyltransferase 1, liver isoform0101
Peroxisome proliferator-activated receptor delta0213
Peroxisome proliferator-activated receptor alpha0213
ATP-binding cassette sub-family C member 80101
ATP-sensitive inward rectifier potassium channel 110101
Thrombin 0011
CDGSH iron-sulfur domain-containing protein 20101
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0102
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Estrogen receptor0102
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Orexin receptor type 10112
Orexin receptor type 20101
polyadenylate-binding protein 10101
Tyrosine-protein kinase ABL10101
Tyrosine-protein kinase ABL20101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
serine/threonine-protein kinase PLK11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 11001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Rap guanine nucleotide exchange factor 32002
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
UDP-glucuronosyltransferase 1A1 0101
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Chain A, Carbonic anhydrase 10101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110001
Polyunsaturated fatty acid 5-lipoxygenase0101
Arachidonate 5-lipoxygenase-activating protein0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 20101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Dihydrofolate reductase0202
Myeloperoxidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Monocarboxylate transporter 100001
Phospholipase A-2-activating protein0101
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
ClpP1001
POsterior Segregation0011
DNA topoisomerase 10101
Alpha-2A adrenergic receptor0101
M-phase inducer phosphatase 10101
Lysosomal alpha-glucosidase0101
Lysosomal alpha-glucosidase0101
Zinc finger protein mex-50011
Butyrophilin subfamily 3 member A10012
Geranylgeranyl pyrophosphate synthase0203
72 kDa type IV collagenase0101
Farnesyl pyrophosphate synthase0202
Neutrophil collagenase0101
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Farnesyl pyrophosphate synthase 0202
Geranylgeranyl pyrophosphate synthase0202
Farnesyl pyrophosphate synthase 0101
H0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]