| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
imidazole
imidazole: RN given refers to parent cpd. 1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1. | 2.04 | 1 | 0 | imidazole | |
s,s'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea
S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea: structure in first source | 2.04 | 1 | 0 | | |
beta-aminoethyl isothiourea
beta-Aminoethyl Isothiourea: A radiation-protective agent that can inhibit DNA damage by binding to the DNA. It also increases the susceptibility of blood cells to complement-mediated lysis. | 2.04 | 1 | 0 | | |
pimagedine
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure. aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. | 2.04 | 1 | 0 | guanidines;
one-carbon compound | EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 1.4.3.4 (monoamine oxidase) inhibitor |
2-aminothiazole
2-aminothiazole: RN given refers to parent cpd; structure. 1,3-thiazol-2-amine : A primary amino compound that is 1,3-thiazole substituted by an amino group at position 2. | 2.04 | 1 | 0 | 1,3-thiazoles;
primary amino compound | |
s-ethyl n-(4-(trifluoromethyl)phenyl)isothiourea
S-ethyl N-(4-(trifluoromethyl)phenyl)isothiourea: structure in first source | 2.04 | 1 | 0 | | |
guanidine
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.. guanidine : An aminocarboxamidine, the parent compound of the guanidines. | 2.03 | 1 | 0 | carboxamidine;
guanidines;
one-carbon compound | |
etiron
etiron: a nitric oxide synthase inhibitor; RN given refers to parent cpd; structure | 2.04 | 1 | 0 | | |
s-methylisothiopseudouronium
S-methylisothiopseudouronium: inhibits nitric oxide synthase; structure in first source | 2.04 | 1 | 0 | | |
arginine
Arginine: An essential amino acid that is physiologically active in the L-form.. arginine : An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group. | 1.99 | 1 | 0 | arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
2-aminothiazoline
2-aminothiazoline: RN given refers to parent cpd; structure in first source & in Negwer, 5th ed, #97. 4,5-dihydro-1,3-thiazol-2-amine : A 1,3-thiazole that is 4,5-dihydro-1,3-thiazole substituted by an amino group at position 2. | 2.04 | 1 | 0 | 1,3-thiazoles;
primary amino compound | |
n-(4-nitrophenacyl)imidazole
N-(4-nitrophenacyl)imidazole: structure in first source | 2.04 | 1 | 0 | | |
1-phenylimidazole
1-phenylimidazole: ligand for cytochrome P-450 & inhibitor of microsomal oxidation | 2.04 | 1 | 0 | | |
3,5-dimethylpyrazole-1-carboxamidine
3,5-dimethylpyrazole-1-carboxamidine: guanidinating reagent for proteins; RN given refers to parent cpd | 2.04 | 1 | 0 | | |
n(g)-iminoethylornithine
[no description available] | 2.04 | 1 | 0 | L-alpha-amino acid | |
2-amino-5-methylthiazole
2-amino-5-methylthiazole: binds the W191G cavity of E coli cytochrome c peroxidase | 2.04 | 1 | 0 | | |
nitroarginine
Nitroarginine: An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6). N(gamma)-nitro-L-arginine : An L-arginine derivative that is L-arginine in which the terminal nitrogen of the guanidyl group is replaced by a nitro group. | 2.04 | 1 | 0 | guanidines;
L-arginine derivative;
N-nitro compound;
non-proteinogenic L-alpha-amino acid | |
vinyl-l-nio
[no description available] | 2.04 | 1 | 0 | | |
1-(4-(3-bromophenoxy)butyl)-1h-imidazole
1-(4-(3-bromophenoxy)butyl)-1H-imidazole: structure in first source | 2.04 | 1 | 0 | | |