beta-aminoethyl isothiourea has been researched along with Hemoglobinuria, Paroxysmal in 21 studies
beta-Aminoethyl Isothiourea: A radiation-protective agent that can inhibit DNA damage by binding to the DNA. It also increases the susceptibility of blood cells to complement-mediated lysis.
Hemoglobinuria, Paroxysmal: A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The affected erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH II and PNH III cells) are abnormally sensitive to complement-mediated lysis." | 1.27 | Characterization of the complement sensitivity of paroxysmal nocturnal hemoglobinuria erythrocytes. ( Parker, CJ; Rosse, WF; Sims, PJ; Wiedmer, T, 1985) |
| "Both normal and HANE serum lysed paroxysmal nocturnal hemoglobinuria (PNH) cells when complement was activated by acidification, CoF and inulin, indicating that the terminal steps of complement were activated in the absence of C4, presumably by the alternate or properdin pathway." | 1.25 | Mechanisms of immune lysis of red blood cells in vitro. I. Paroxysmal nocturnal hemoglobinuria cells. ( Adams, JP; Logue, GL; Rosse, WF, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (95.24) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SIRCHIA, G | 10 |
| FERRONE, S | 9 |
| MERCURIALI, F | 4 |
| Dacie, JV | 2 |
| Falezza, GC | 1 |
| Corrocher, R | 3 |
| Olivieri, O | 1 |
| Capra, F | 1 |
| Trevisoi, E | 1 |
| Pennacchioni, A | 1 |
| De Sandre, G | 3 |
| Advani, H | 1 |
| Zamor, J | 1 |
| Judd, WJ | 1 |
| Johnson, CL | 1 |
| Marsh, WL | 1 |
| Burapakulsolsri, N | 1 |
| Yuthavong, Y | 1 |
| Wilairat, P | 1 |
| Ezzell, JL | 1 |
| Wilcox, LA | 1 |
| Bernshaw, NJ | 1 |
| Parker, CJ | 2 |
| Wiedmer, T | 1 |
| Sims, PJ | 1 |
| Rosse, WF | 3 |
| Guarini, L | 1 |
| Bassetto, MA | 1 |
| Rabusin, P | 1 |
| Tedesco, F | 1 |
| Jirillo, E | 1 |
| Dierich, MP | 1 |
| Pellegrino, MA | 1 |
| Reisfeld, RA | 1 |
| Lewis, SM | 2 |
| Kabakçi, T | 1 |
| Logue, GL | 2 |
| Adams, JP | 1 |
| Marubini, E | 2 |
| Lambertenghi, G | 1 |
| Canellos, GP | 1 |
| Brain, MC | 1 |
| Zanella, A | 1 |
| D'Amico, G | 1 |
| Romagnoni, M | 1 |
2 reviews available for beta-aminoethyl isothiourea and Hemoglobinuria, Paroxysmal
| Article | Year |
|---|---|
The laboratory substitutes of the red cell of paroxysmal nocturnal haemoglobinuria (PNH): PNH-like red cells.
Topics: beta-Aminoethyl Isothiourea; Cell Survival; Circadian Rhythm; Complement System Proteins; Cysteine; | 1972 |
PNH: disease or defect?
Topics: Adult; Anemia, Aplastic; Autoantibodies; beta-Aminoethyl Isothiourea; Blood Transfusion; Bone Marrow | 1972 |
19 other studies available for beta-aminoethyl isothiourea and Hemoglobinuria, Paroxysmal
| Article | Year |
|---|---|
THE ACTION OF TWO SULFHYDRYL COMPOUNDS ON NORMAL HUMAN RED CELLS. RELATIONSHIP TO RED CELLS OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA.
Topics: beta-Aminoethyl Isothiourea; Calcium; Cell Death; Complement System Proteins; Cysteine; Dextrans; Er | 1965 |
Immune lysis of AET-treated normal red cells (PNH-like cells).
Topics: beta-Aminoethyl Isothiourea; Cell Membrane; Complement System Proteins; Cysteine; Erythrocytes; Hemo | 1967 |
In vitro production of PNH-like red blood cells by 2-mercaptopropionylglycine.
Topics: Acetylcholine; Acetylcholinesterase; Amino Acids, Sulfur; beta-Aminoethyl Isothiourea; Choline; Eryt | 1980 |
Inactivation of Kell blood group antigens by 2-aminoethylisothiouronium bromide.
Topics: beta-Aminoethyl Isothiourea; Blood Group Antigens; Erythrocytes; Hemoglobinuria, Paroxysmal; Humans; | 1982 |
An examination of complement proteins on membranes of paroxysmal nocturnal haemoglobinuria (PNH) and PNH-like red cells.
Topics: beta-Aminoethyl Isothiourea; Blood Protein Electrophoresis; Complement System Proteins; Erythrocyte | 1979 |
Induction of the paroxysmal nocturnal hemoglobinuria phenotype in normal human erythrocytes: effects of 2-aminoethylisothiouronium bromide on membrane proteins that regulate complement.
Topics: Antibodies; Antigens, Differentiation; beta-Aminoethyl Isothiourea; CD55 Antigens; CD59 Antigens; Co | 1991 |
Characterization of the complement sensitivity of paroxysmal nocturnal hemoglobinuria erythrocytes.
Topics: beta-Aminoethyl Isothiourea; Cobra Cardiotoxin Proteins; Complement Activation; Complement C3; Compl | 1985 |
[Modifications of membrane antigen reactivity in PNH-like erythrocytes (author's transl)].
Topics: ABO Blood-Group System; beta-Aminoethyl Isothiourea; Blood Group Antigens; Cell Membrane; Coombs Tes | 1974 |
Reactive haemolysis test in paroxysmal nocturnal haemoglobinuria.
Topics: Acids; beta-Aminoethyl Isothiourea; Complement System Proteins; Erythrocytes; Hemoglobinuria, Paroxy | 1974 |
Chemical modulation of cell surfaces by sulfhydryl compounds: effect on C3b receptors.
Topics: ABO Blood-Group System; Acetamides; Animals; beta-Aminoethyl Isothiourea; Binding Sites, Antibody; C | 1974 |
The lysis of paroxysmal nocturnal haemoglobinuria red cells by serum and cobra factor.
Topics: Animals; beta-Aminoethyl Isothiourea; Complement System Proteins; Edetic Acid; Erythrocytes; Glutath | 1972 |
Mechanisms of immune lysis of red blood cells in vitro. I. Paroxysmal nocturnal hemoglobinuria cells.
Topics: Angioedema; beta-Aminoethyl Isothiourea; Binding Sites; Cell Membrane; Cells, Cultured; Complement F | 1973 |
Study of two in vitro diagnostic tests for paroxysmal nocturnal haemoglobinuria.
Topics: Analysis of Variance; beta-Aminoethyl Isothiourea; Circadian Rhythm; Erythrocytes; Hemoglobinuria, P | 1973 |
In-vitro lysis of AET-treated normal red cells (PNH-like cells) by normal and cirrhotic sera.
Topics: beta-Aminoethyl Isothiourea; Complement System Proteins; Erythrocytes; Hemoglobinuria, Paroxysmal; H | 1969 |
Study of in vitro lysis of paroxysmal nocturnal haemoglobinuria (PNH) and PNH-like red cells.
Topics: beta-Aminoethyl Isothiourea; Complement System Proteins; Erythrocytes; Erythrocytes, Abnormal; Hemog | 1972 |
Electron microscope study of PNH red cells and AET-treated normal red cells (PNH-like cells).
Topics: beta-Aminoethyl Isothiourea; Cell Membrane; Erythrocytes; Erythrocytes, Abnormal; Hemoglobinuria, Pa | 1971 |
Effects of sulphydryl inhibition on the erythrocyte in paroxysmal nocturnal haemoglobinuria.
Topics: Adult; Aged; beta-Aminoethyl Isothiourea; Cell Membrane; Chloromercuribenzoates; Erythrocytes; Femal | 1970 |
Study of the acetylcholinesterase activity of AET-treated (2-aminoethylisothiouronium bromide) normal red cells (PNH-like cells).
Topics: Acetylcholinesterase; beta-Aminoethyl Isothiourea; Complement System Proteins; Enzyme Repression; Er | 1970 |
Cation transport in normal human red cells treated with sulfhydryl compounds.
Topics: beta-Aminoethyl Isothiourea; Biological Transport, Active; Cysteine; Erythrocytes; Hemoglobinuria, P | 1966 |