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beta-aminoethyl isothiourea and Hemolysis

beta-aminoethyl isothiourea has been researched along with Hemolysis in 23 studies

beta-Aminoethyl Isothiourea: A radiation-protective agent that can inhibit DNA damage by binding to the DNA. It also increases the susceptibility of blood cells to complement-mediated lysis.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
"The affected erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH II and PNH III cells) are abnormally sensitive to complement-mediated lysis."1.27Characterization of the complement sensitivity of paroxysmal nocturnal hemoglobinuria erythrocytes. ( Parker, CJ; Rosse, WF; Sims, PJ; Wiedmer, T, 1985)
"Both normal and HANE serum lysed paroxysmal nocturnal hemoglobinuria (PNH) cells when complement was activated by acidification, CoF and inulin, indicating that the terminal steps of complement were activated in the absence of C4, presumably by the alternate or properdin pathway."1.25Mechanisms of immune lysis of red blood cells in vitro. I. Paroxysmal nocturnal hemoglobinuria cells. ( Adams, JP; Logue, GL; Rosse, WF, 1973)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199020 (86.96)18.7374
1990's2 (8.70)18.2507
2000's0 (0.00)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
des Roziers, NB1
Bodivit, G1
Chadebech, P1
Nzouakou, R1
Bierling, P1
Noizat-Pirenne, F1
SIRCHIA, G9
FERRONE, S7
MERCURIALI, F4
Dacie, JV2
Falezza, GC1
Corrocher, R4
Olivieri, O1
Capra, F1
Trevisoi, E1
Pennacchioni, A1
De Sandre, G4
Madsen, M1
Johnsen, HE1
Hansen, PW1
Christiansen, SE1
Test, ST1
Mitsuyoshi, J1
Ezzell, JL1
Wilcox, LA1
Bernshaw, NJ1
Parker, CJ2
Wiedmer, T1
Sims, PJ1
Rosse, WF3
Tedesco, F1
Jirillo, E1
Lewis, SM1
Kahn, G2
Curry, MC2
Dustin, R1
Kabakçi, T1
Logue, GL2
Adams, JP1
Marubini, E2
Lambertenghi-Deliliers, G1
Ranzi, T1
Cortesi, S2
Falezza, G1
Perona, G2
Canellos, GP1
Brain, MC1
Zanella, A1
Vettore, L1

Reviews

2 reviews available for beta-aminoethyl isothiourea and Hemolysis

ArticleYear
The laboratory substitutes of the red cell of paroxysmal nocturnal haemoglobinuria (PNH): PNH-like red cells.
    Series haematologica (1968), 1972, Volume: 5, Issue:3

    Topics: beta-Aminoethyl Isothiourea; Cell Survival; Circadian Rhythm; Complement System Proteins; Cysteine;

1972
PNH: disease or defect?
    British journal of haematology, 1972, Volume: 23

    Topics: Adult; Anemia, Aplastic; Autoantibodies; beta-Aminoethyl Isothiourea; Blood Transfusion; Bone Marrow

1972

Other Studies

21 other studies available for beta-aminoethyl isothiourea and Hemolysis

ArticleYear
Anti-T haemolysins: the effects of sialic acid removal and 2-aminoethylisothiouronium bromide treatment of erythrocytes on immune lysis.
    Vox sanguinis, 2011, Volume: 100, Issue:4

    Topics: Antigens, Tumor-Associated, Carbohydrate; beta-Aminoethyl Isothiourea; Blood Group Incompatibility;

2011
THE ACTION OF TWO SULFHYDRYL COMPOUNDS ON NORMAL HUMAN RED CELLS. RELATIONSHIP TO RED CELLS OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA.
    Blood, 1965, Volume: 25

    Topics: beta-Aminoethyl Isothiourea; Calcium; Cell Death; Complement System Proteins; Cysteine; Dextrans; Er

1965
Immune lysis of AET-treated normal red cells (PNH-like cells).
    Nature, 1967, Aug-12, Volume: 215, Issue:5102

    Topics: beta-Aminoethyl Isothiourea; Cell Membrane; Complement System Proteins; Cysteine; Erythrocytes; Hemo

1967
In vitro production of PNH-like red blood cells by 2-mercaptopropionylglycine.
    Acta haematologica, 1980, Volume: 64, Issue:6

    Topics: Acetylcholine; Acetylcholinesterase; Amino Acids, Sulfur; beta-Aminoethyl Isothiourea; Choline; Eryt

1980
Isolation of human T and B lymphocytes by E-rosette gradient centrifugation. Characterization of the isolated subpopulations.
    Journal of immunological methods, 1980, Volume: 33, Issue:4

    Topics: B-Lymphocytes; beta-Aminoethyl Isothiourea; Cell Separation; Centrifugation, Density Gradient; Cold

1980
Calcium-loaded erythrocytes have a defect in complement regulation distinct from that resulting from exposure to 2-aminoethylisothiouronium bromide.
    Blood, 1995, Oct-01, Volume: 86, Issue:7

    Topics: Adult; Antigens, CD; beta-Aminoethyl Isothiourea; Calcium; CD59 Antigens; Complement C3b; Complement

1995
Induction of the paroxysmal nocturnal hemoglobinuria phenotype in normal human erythrocytes: effects of 2-aminoethylisothiouronium bromide on membrane proteins that regulate complement.
    Blood, 1991, Jun-15, Volume: 77, Issue:12

    Topics: Antibodies; Antigens, Differentiation; beta-Aminoethyl Isothiourea; CD55 Antigens; CD59 Antigens; Co

1991
Characterization of the complement sensitivity of paroxysmal nocturnal hemoglobinuria erythrocytes.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:6

    Topics: beta-Aminoethyl Isothiourea; Cobra Cardiotoxin Proteins; Complement Activation; Complement C3; Compl

1985
Reactive haemolysis test in paroxysmal nocturnal haemoglobinuria.
    Haematologica, 1974, Volume: 59, Issue:3

    Topics: Acids; beta-Aminoethyl Isothiourea; Complement System Proteins; Erythrocytes; Hemoglobinuria, Paroxy

1974
New approaches to investigating UVL photo protective substances in vitro.
    Archiv fur dermatologische Forschung, 1973, Volume: 248, Issue:3

    Topics: 1-Propanol; Aminobenzoates; Aniline Compounds; beta-Aminoethyl Isothiourea; Candida albicans; Chlorp

1973
The lysis of paroxysmal nocturnal haemoglobinuria red cells by serum and cobra factor.
    British journal of haematology, 1972, Volume: 23, Issue:6

    Topics: Animals; beta-Aminoethyl Isothiourea; Complement System Proteins; Edetic Acid; Erythrocytes; Glutath

1972
Mechanisms of immune lysis of red blood cells in vitro. I. Paroxysmal nocturnal hemoglobinuria cells.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:5

    Topics: Angioedema; beta-Aminoethyl Isothiourea; Binding Sites; Cell Membrane; Cells, Cultured; Complement F

1973
Study of two in vitro diagnostic tests for paroxysmal nocturnal haemoglobinuria.
    British journal of haematology, 1973, Volume: 24, Issue:6

    Topics: Analysis of Variance; beta-Aminoethyl Isothiourea; Circadian Rhythm; Erythrocytes; Hemoglobinuria, P

1973
Ultraviolet light protection by several new compounds.
    Archives of dermatology, 1974, Volume: 109, Issue:4

    Topics: Administration, Topical; Aminobenzoates; Anthracenes; Antioxidants; beta-Aminoethyl Isothiourea; Bro

1974
In-vitro lysis of AET-treated normal red cells (PNH-like cells) by normal and cirrhotic sera.
    British journal of haematology, 1969, Volume: 17, Issue:3

    Topics: beta-Aminoethyl Isothiourea; Complement System Proteins; Erythrocytes; Hemoglobinuria, Paroxysmal; H

1969
Study of in vitro lysis of paroxysmal nocturnal haemoglobinuria (PNH) and PNH-like red cells.
    British journal of haematology, 1972, Volume: 23, Issue:1

    Topics: beta-Aminoethyl Isothiourea; Complement System Proteins; Erythrocytes; Erythrocytes, Abnormal; Hemog

1972
Immune lysis of normal and AET-treated lymphocytes: a study of transmission and scanning electron microscopy.
    Blood, 1971, Volume: 38, Issue:6

    Topics: Antigen-Antibody Reactions; beta-Aminoethyl Isothiourea; Complement System Proteins; Cytotoxicity Te

1971
On the mechanism of the in vitro production of Ham-positive red cells by sulphydryl compounds: role of pH and Free -SH groups.
    British journal of haematology, 1970, Volume: 18, Issue:5

    Topics: beta-Aminoethyl Isothiourea; Blood Group Antigens; Cysteine; Erythrocytes; Glutathione Reductase; He

1970
Effects of sulphydryl inhibition on the erythrocyte in paroxysmal nocturnal haemoglobinuria.
    British journal of haematology, 1970, Volume: 18, Issue:3

    Topics: Adult; Aged; beta-Aminoethyl Isothiourea; Cell Membrane; Chloromercuribenzoates; Erythrocytes; Femal

1970
Study of the acetylcholinesterase activity of AET-treated (2-aminoethylisothiouronium bromide) normal red cells (PNH-like cells).
    Acta vitaminologica et enzymologica, 1970, Volume: 24, Issue:6

    Topics: Acetylcholinesterase; beta-Aminoethyl Isothiourea; Complement System Proteins; Enzyme Repression; Er

1970
Ham-positive red cells induced in vitro by N-acetylcysteine or D-penicillamine.
    British journal of haematology, 1968, Volume: 15, Issue:5

    Topics: Acetylcholinesterase; Acetylcysteine; beta-Aminoethyl Isothiourea; Cysteine; Erythrocytes; Hemolysis

1968