| Assay ID | Title | Year | Journal | Article |
|---|
| AID412448 | Inhibition of human recombinant nNOS at 100 uM | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| AID67988 | Selectivity index which is the ratio of the Ki or IC50 values of recombinant bovine Endothelial nitric oxide synthase and bovine brain nNOS (Neuronal nitric oxide synthase) | 1999 | Journal of medicinal chemistry, Aug-12, Volume: 42, Issue:16
| N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase. |
| AID412445 | Inhibition of human DDAH1 by plate-reader assay | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| AID67989 | Selectivity index which is the ratio of the Ki or IC50 values of recombinant bovine eNOS (Endothelial nitric oxide synthase) / recombinant murine iNOS (Inducible nitric oxide synthase) | 1999 | Journal of medicinal chemistry, Aug-12, Volume: 42, Issue:16
| N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase. |
| AID1581787 | Inhibition of neuronal NOS (unknown origin) assessed as formation of methemoglobin from oxyhemoglobin at 1 mM using L-arginine as substrate in presence of oxyhemoglobin and NADPH by UV-vis spectrophotometry relative to control | 2020 | Journal of medicinal chemistry, 01-09, Volume: 63, Issue:1
| Discovery of |
| AID412453 | Inhibition of human recombinant iNOS at 100 uM | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| AID412450 | Inhibition of human recombinant iNOS at 1 uM | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| AID1581786 | Inhibition of bovine liver arginase at 1 mM using L-arginine as substrate measured after 30 mins by colder reagent based microplate reader assay relative to control | 2020 | Journal of medicinal chemistry, 01-09, Volume: 63, Issue:1
| Discovery of |
| AID412452 | Inhibition of human recombinant eNOS at 1 uM | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| AID1581788 | Inhibition of endothelial NOS (unknown origin) assessed as formation of methemoglobin from oxyhemoglobin at 1 mM using L-arginine as substrate in presence of oxyhemoglobin and NADPH by UV-vis spectrophotometry relative to control | 2020 | Journal of medicinal chemistry, 01-09, Volume: 63, Issue:1
| Discovery of |
| AID412449 | Inhibition of human recombinant eNOS at 100 uM | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| AID404423 | Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrulline | 2008 | Bioorganic & medicinal chemistry, Jun-01, Volume: 16, Issue:11
| Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase. |
| AID1581785 | Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder reagent based microplate reader assay | 2020 | Journal of medicinal chemistry, 01-09, Volume: 63, Issue:1
| Discovery of |
| AID412444 | Inhibition of human DDAH1 at 1 mM by HPLC | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| AID412451 | Inhibition of human recombinant nNOS at 1 uM | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| AID412455 | Inhibition of human recombinant NOS | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| AID1581789 | Inhibition of iNOS (unknown origin) assessed as formation of methemoglobin from oxyhemoglobin at 1 mM using L-arginine as substrate in presence of oxyhemoglobin and NADPH by UV-vis spectrophotometry relative to control | 2020 | Journal of medicinal chemistry, 01-09, Volume: 63, Issue:1
| Discovery of |
| AID1803038 | In Vitro hDDAH-1 Assay from Article 10.3109/14756366.2011.573480: \\Designing modulators of dimethylarginine dimethylaminohydrolase (DDAH): a focus on selectivity over arginase.\\ | 2012 | Journal of enzyme inhibition and medicinal chemistry, Feb, Volume: 27, Issue:1
| Designing modulators of dimethylarginine dimethylaminohydrolase (DDAH): a focus on selectivity over arginase. |
| AID1345168 | Human NG,NG-Dimethylarginine dimethylaminohydrolase 1 (Dimethylarginine dimethylaminohydrolases) | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |