Page last updated: 2024-12-06

methyl tetradecanoate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Methyl tetradecanoate, also known as myristate, is a fatty acid methyl ester that occurs naturally in various plants and animals. It is synthesized by the esterification of myristic acid with methanol. Methyl tetradecanoate is a colorless, odorless liquid with a melting point of -1°C and a boiling point of 295°C. It is used in the production of various cosmetics, pharmaceuticals, and food additives. Methyl tetradecanoate is also a potential biofuel due to its high energy content and low viscosity. It is studied for its potential applications in various industries, including cosmetics, pharmaceuticals, and biofuel production. The compound is also investigated for its potential effects on human health, including its role in lipid metabolism and its potential benefits for skin health.'
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methyl tetradecanoate: component of fabric detergents [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

methyl tetradecanoate : A fatty acid methyl ester resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with methanol. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID31284
CHEMBL ID207549
CHEBI ID89199
SCHEMBL ID158121
MeSH IDM0495592

Synonyms (66)

Synonym
methyl myristate
methyl tetradecanoate
myristic acid, methyl ester
tetradecanoic acid, methyl ester
124-10-7
nsc-5029
methyl n-tetradecanoate
metholeneat 2495
uniphat a50
nsc5029
methyl myristate, >=99% (gc)
methyl myristate, >=98%, fg
NCGC00164312-01
F205A716-B088-445E-981A-7037783C0147
tetradecanoic acid methyl ester (fame mix)
myristic acid methyl ester
chebi:89199 ,
CHEMBL207549
tetradecanoic acid methyl ester
M0482
AKOS004910358
NCGC00164312-02
LMFA07010467
we(1:0/14:0)
cas-124-10-7
tox21_200012
dtxcid607019
NCGC00257566-01
dtxsid5027019 ,
FT-0686716
ec 204-680-1
nsc 5029
einecs 204-680-1
fema no. 2722
unii-rg9851783c
hsdb 5602
ai3-01980
rg9851783c ,
methyl myristate [hsdb]
methyl myristate [usp-rs]
methyl myristate [fhfi]
methyl myristate [inci]
SCHEMBL158121
methyltetradecanoate
methyl myristylate
emery 2214
acide myristique methyl ester
mfcd00008983
formyl tetradecanoate
STL453780
J-005043
methyl myristate, analytical standard
methyl myristate, united states pharmacopeia (usp) reference standard
methyl myristate, certified reference material, tracecert(r)
tetradecanoic acid-methyl ester
c14 fame
CS-W004288
methylmyristate
myristic acid, methyl ester (8ci)
methyl-myristate
Q27161384
2,6-dimethylbenzeneboronicacid
H10750
methyl tetradecanoate; methyl myristate 99%; myristic acid methyl ester; tetradecanoic acid methyl ester
A890596
HY-W004288
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (3)

RoleDescription
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
flavouring agentA food additive that is used to added improve the taste or odour of a food.
fragranceA substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
fatty acid methyl esterA fatty acid ester that is the carboxylic ester obtained by the formal condensation of a fatty acid with methanol.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
RAR-related orphan receptor gammaMus musculus (house mouse)Potency30.54440.006038.004119,952.5996AID1159521
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency0.00220.023723.228263.5986AID588543
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency61.13060.000627.21521,122.0200AID651741
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID264976Antibacterial activity against Staphylococcus aureus2006Bioorganic & medicinal chemistry letters, Jun-01, Volume: 16, Issue:11
Design, synthesis, antibacterial, and QSAR studies of myristic acid derivatives.
AID264977Antibacterial activity against Micrococcus luteus2006Bioorganic & medicinal chemistry letters, Jun-01, Volume: 16, Issue:11
Design, synthesis, antibacterial, and QSAR studies of myristic acid derivatives.
AID264978Antibacterial activity against Escherichia coli2006Bioorganic & medicinal chemistry letters, Jun-01, Volume: 16, Issue:11
Design, synthesis, antibacterial, and QSAR studies of myristic acid derivatives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 38.33

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index38.33 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.28 (4.65)
Search Engine Demand Index46.12 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (38.33)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]