bisabolol and alpha-bergamotene

The chemical composition of the essential oil obtained from aerial parts of Nepeta graciliflora was analysed, for the first time, by GC-FID and GC-MS. A total of 27 compounds were identified, constituting over 91.44% of oil composition. The oil was strongly characterised by sesquiterpenes (86.72%), with β-sesquiphellandrene (28.75%), caryophyllene oxide (12.15%), α-bisabolol (8.97%), α-bergamotene (8.51%), β-bisabolene (6.33%) and β-Caryophyllene (5.34%) as the main constituents. The in vitro activity of the essential oil was determined against four micro-organisms in comparison with chloramphenicol by the agar well diffusion and broth dilution method. The oil exhibited good activity against all tested organisms.

Topics: Anti-Bacterial Agents; Bridged Bicyclo Compounds; Gas Chromatography-Mass Spectrometry; Microbial Sensitivity Tests; Monocyclic Sesquiterpenes; Nepeta; Oils, Volatile; Polycyclic Sesquiterpenes; Sesquiterpenes