Compounds > polyethylene glycol monostearate
Page last updated: 2024-12-06

polyethylene glycol monostearate

Description

2-hydroxyethyl octadecanoate : An octadecanoate ester obtained by formal condensation between the carboxy group of octadecanoic (stearic) acid and one of the hydroxy groups of ethylene glycol. It is an ingredient in many personal care products and cosmetics. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID24762
CHEMBL ID2355383
CHEBI ID167626
CHEBI ID32027
SCHEMBL ID10412
MeSH IDM0053906

Synonyms (175)

Synonym
ethylene glycol monostearate se
unii-6yly96tql6
6yly96tql6 ,
glycol stearate se
86418-55-5
glycol monostearate se
tegin g
octadecanoic acid 2-hydroxyethyl ester
CHEBI:167626
AKOS015843173
myrj 52s
peg 42
emcol h 35-a
peg 100ms
cerasynt 660
ethofat 60/20
nonex 29
empilan cq-100
nsc-31811
cremophor a
myrj
mys 40
perphinol 45/100
nissan nonion s 15
arosurf 1855e40
nonex 28
prodhybase 4000
peg-150 stearate
nonion s 4
myrj 51
nonion s 15
myrj 53
cerasynt m
crill 20,22,23
stabilisant .delta.-118
s 541
peg 1000ms
nikkol mys 40
nikkol mys 4
9004-99-3
lipal 400-s
prodhybase p
stearoks 920
nonex 54
peg 600ms
stearoxa-6
empilan cp-100
clearate g
myrj 52
lipal 15s
lactine
usaf ke-9
ethofat 60/25
peg-8 stearate
nsc31811
nonex 63
cerasynt mn
akyporox s 100
s 1004
soromin-sg
peg stearate
nissan nonion s-2
nonion s 2
glycols, monostearate
ionet ms-1000
usaf ke-12
cithrol 10ms
nikkol mys-25
mys 45
stenol 8
pegosperse s 9
s 1012
s 1054
kessco x-211
x-489-r
lx 3
cithrol ps
nikkol mys
nonex 36
emunon 3115
lipo-peg 4-s
myrj 45
myrj 59
s 1116
emanon 3113
myrj 49
nikkol mys 45
nonex 53
emery 15393
trydet sa 40
stearox 6
stearox 920
usaf ke-14
stearoks 6
emerest 2640
lamacit ca
ethofat 60/15
peg-40 stearate
111-60-4
magi 45
pms no. 1
pms no. 2
emanon 3199
trydet sa series
stabilisant delta-118
17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl octadecanoate
slovasol mks 16
emulphor vt-650
peg-10 stearate
stearic acid, 2-hydroxyethyl ester
octadecanoic acid, 2-hydroxyethyl ester
crill 20,21,22, 23
2-hydroxyethyl octadecanoate
2-hydroxyethyl stearate
D01542
myrj 52 (tn)
macrogol ester (inn)
monthybase
ethylene glycol stearate
ethylene glycol, monostearate
lipo egms
parastarin
brn 1794033
empilan 2848
glycol monostearate
clindrol seg
prodhybas n
usaf ke-11
s 151
monthyle
glycol stearate
emerest 2350
prodhybase ethyl
einecs 203-886-9
stearic acid, monoester with ethylene glycol
ethylene glycol monostearate
tego-stearate
ivorit
sedetol
L001305
NCGC00188435-01
tox21_113036
cas-111-60-4
dtxcid006881
dtxsid5026881 ,
unii-0324g66d0e
0324g66d0e ,
FT-0626337
glycol stearate [vandf]
glycol stearate [ii]
glycol stearate [inci]
ethylene glycol monostearate [who-dd]
SCHEMBL10412
ethyleneglycol monostearate
peg40 stearate
CHEMBL2355383
schercemol egms
alkamuls egms/c
pegosperse 50 ms
ablunol egms
alkamuls seg
cerasynt mn (salt/mix)
cerasynt m (salt/mix)
W-109413
macrogol ester
CHEBI:32027 ,
Q5572621
mfcd00051465
n,n-bis-(1-phenyl-ethyl)-malonamide
BS-48654
CS-0440899
peg 2000 ms
poly(oxy-1,2-ethanediyl), a-(1-oxooctadecyl)-w-hydroxy-
F71256
F71203

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs."( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019)		0.51
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Occurs in Manufacturing (52 Product(s))

Product Categories

Product CategoryProducts
Beauty & Personal Care42
Household Essentials6
Baby & Kids Products4

Products

ProductBrandCategoryCompounds Matched from IngredientsDate Retrieved
Aveeno Skin Relief Body Wash -- 18 fl ozAveenoBeauty & Personal CareCocamidopropyl Betaine, Decyl Glucoside, Sodium Laureth Sulfate, Glycerin, Oat, Glycol Stearate, Propylene Glycol2024-11-29 10:47:42
Better Life Liquid Soap Naturally Skin-Soothing Citrus Mint -- 12 fl ozBetter LifeHousehold Essentialsorange, vitamin E, decyl glucoside, ethylhexylglycerin, vitamin E, glycerin, phenoxyethanol, PEG-150 stearate2024-11-29 10:47:42
Better Life Liquid Soap Naturally Skin-Soothing Scent Free -- 12 fl ozBetter LifeHousehold Essentialsvitamin E, decyl glucoside, ethylhexylglycerin, vitamin E, glycerin, phenoxyethanol, PEG-150 stearate2024-11-29 10:47:42
Cantu Shea Butter for Natural Hair Deep Treatment Masque -- 12 ozCantuBeauty & Personal Carecetyl alcohol, glycerin, phenoxyethanol, glycol stearate2024-11-29 10:47:42
Cantu Shea Butter for Natural Hair Leave-In Conditioning Cream -- 12 ozCantuBeauty & Personal Carecetyl alcohol, glycerin, phenoxyethanol, glycol stearate2024-11-29 10:47:42
CeraVe Hydrating Facial Cleanser For Normal to Dry Skin -- 12 fl ozCeraVeBeauty & Personal Carecarbomer, ceramide NP, cetearyl alcohol, cetyl alcohol, tocopherol, disodium EDTA, tocopherol, glyceryl stearate, glycerin, phenoxyethanol, phytosphingosine, PEG-40 stearate, potassium phosphate, stearyl alcohol2024-11-29 10:47:42
CeraVe Hydrocortisone Anti-Itch Cream -- 1 ozCeraVeBeauty & Personal Carecitric acid,, benzyl alcohol, carbomer, ceramide NP, cetearyl alcohol, cetyl palmitate, dimethyl MEA, cyclopentasiloxane, glycerin, isopropyl myristate, maltodextrin, methylparaben, niacinamide, oat, phenoxyethanol, phytosphingosine, PEG-40 stearate2024-11-29 10:47:42
Citrus Magic Closet Moisture Absorber and Odor Eliminator Solid Crisp Linen -- 12.8 ozCitrus MagicHousehold Essentialsglycerin, glycol monostearate, propylene glycol, potassium stearate2024-11-29 10:47:42
Dead Sea Naturals Facial Day Cream -- 1.7 fl ozDead Sea NaturalsBeauty & Personal Carecaprylyl glycol, alanine, allantoin, cetyl alcohol, chlorphenesin, tocopherol, tocopherol, vitamin E, glyceryl stearate, glycerin, glycine, dimethicone, hexyl cinnamal, isopropyl myristate, lactic acid, linalool, phenoxyethanol, peg-40 stearate, propanediol, sodium benzoate, urea2024-11-29 10:47:42
Dead Sea Naturals Purifying Mud Mask -- 3.4 fl ozDead Sea NaturalsBeauty & Personal Carecaprylyl glycol, citric acid, ascorbyl palmitate, allantoin, cetearyl alcohol, chlorphenesin, citric acid, tocopherol, panthenol, pro vitamin B5, tocopherol, vitamin E, glyceryl stearate, glycerin, dimethicone, hydroxyethylcellulose, kaolin, lactic acid, phenoxyethanol, PEG-40 stearate, propylene glycol, beta-sitosterol, sodium benzoate, sodium lactate, squalene, stearyl alcohol, zinc oxide2024-11-29 10:47:42
Dead Sea Naturals Skincare Starter Kit -- 1 KitDead Sea NaturalsBeauty & Personal Carecaprylyl glycol, butylene glycol, aminomethyl propanol, methylpropanediol, citric acid, ascorbyl palmitate, alanine, allantoin, ascorbyl glucoside, ascorbic acid, bisabolol, cetearyl alcohol, cetyl alcohol, cetyl palmitate, chlorphenesin, citric acid, cocamidopropyl betaine, tocopherol, panthenol, pro vitamin B5, ethylhexylglycerin, farnesol, tocopherol, vitamin E, glyceryl stearate, glycerin, glycine, dimethicone, hexyl cinnamal, hydroxyethylcellulose, pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, isopropyl myristate, kaolin, lactic acid, linalool, niacinamide, phenoxyethanol, peg-40 stearate, propylene glycol, salicylic acid, beta-sitosterol, sodium benzoate, sodium citrate, sodium hydroxide, sodium lactate, squalene, stearyl alcohol, trehalose, urea, zinc oxide2024-11-29 10:47:42
Dead Sea Naturals Soothing Body Cream -- 6.8 fl ozDead Sea NaturalsBeauty & Personal Carecaprylyl glycol, allantoin, cetearyl alcohol, cetyl alcohol, chlorphenesin, cinnamyl alcohol, coumarin, coumarin, tocopherol, tocopherol, vitamin E, glyceryl stearate, glycerin, dimethicone, lactic acid, limonene, linalool, phenoxyethanol, PEG -40 stearate, propylene glycol, zinc oxide2024-11-29 10:47:42
Dead Sea Naturals Soothing Hand Cream -- 3.4 fl ozDead Sea NaturalsBeauty & Personal Carecaprylyl glycol, ascorbyl palmitate, allantoin, cetearyl alcohol, chlorphenesin, cinnamyl alcohol, coumarin, coumarin, tocopherol, tocopherol, vitamin E, glyceryl stearate, glycerin, dimethicone, lactic acid, limonene, linalool, phenoxyethanol, PEG-40 stearate, propylene glycol, beta-sitosterol, sodium lactate, squalene, stearyl alcohol, zinc oxide2024-11-29 10:47:42
Earth Science A-D-E Creamy Cleanser -- 8 fl ozEarth ScienceBeauty & Personal Careglyceryl dilaurate, allantoin, ascorbic acid, tocopherol, tocopherol, glyceryl stearate, glycerin, lactic acid, phenoxyethanol, PEG-8 stearate, retinyl palmitate, ergocalciferol2024-11-29 10:47:42
EOS Ultra Moisturizing Shave Cream Pomegranate Raspberry -- 7 fl ozEOSBeauty & Personal Careascorbyl palmitate, red 40, carbomer, cetyl alcohol, disodium EDTA, glyceryl stearate, glycerin, dimethicone, hexyl cinnamal, butylphenyl methylpropional, linalool, oat, glycol stearate, propylene glycol, sodium benzoate, stearic acid, titanium dioxide, triethanolamine2024-11-29 10:47:42
EOS Ultra Moisturizing Shave Cream Vanilla Bliss -- 7 fl ozEOSBeauty & Personal Careascorbyl palmitate, red 40, gluconolactone, carbomer, cetyl alcohol, disodium EDTA, glyceryl stearate, glycerin, dimethicone, oat, glycol stearate, propylene glycol, sodium benzoate, stearic acid, yellow 5, titanium dioxide, triethanolamine2024-11-29 10:47:42
Eucerin Skin Calming Daily Moisturizing Creme -- 8 ozEucerinBeauty & Personal Carebenzyl alcohol, carbomer, cetyl alcohol, cetyl palmitate, glyceryl stearate, glycerin, dimethicone, octyldodecanol, phenoxyethanol, piroctone olamine, PEG-40 stearate2024-11-29 10:47:42
Eucerin Skin Calming Daily Moisturizing Creme Fragrance Free -- 14 ozEucerinBeauty & Personal Caremethylpropanediol, benzyl alcohol, carbomer, cetyl alcohol, cetyl palmitate, glyceryl stearate, glycerin, dimethicone, octyldodecanol, phenoxyethanol, piroctone olamine, PEG-40 stearate2024-11-29 10:47:42
Every Man Jack 2-in-1 Shampoo + Conditioner - Cedarwood -- 13.5 fl ozEvery Man JackBeauty & Personal Carecitric acid, benzyl alcohol, citric acid, cocamidopropyl betaine, tocopherol, panthenol, tocopherol, glycerin, trisodium ethylenediamine disuccinate, vitamin b5, phenoxyethanol, glycol stearate2024-11-29 10:47:42
Every Man Jack 2-In-1 Shampoo + Conditioner - Sandalwood -- 13.5 fl ozEvery Man JackBeauty & Personal Carechamomile, cocoamidopropyl betaine, decyl glucoside, panthenol, glycerin, butylphenyl methylpropional, limonene, linalool, glycol stearate2024-11-29 10:47:42
Every Man Jack 2-In-1 Shampoo + Conditioner - Sea Salt -- 13.5 fl ozEvery Man JackBeauty & Personal Caregeranium, citric acid, citric acid, cocamidopropyl betaine, decyl glucoside, panthenol, ethylhexylglycerin, glycerin, linalool, vitamin B5, phenoxyethanol, glycol stearate, sodium benzoate2024-11-29 10:47:42
Every Man Jack 2-In-1 Shampoo + Conditioner - Tea Tree -- 13.5 fl ozEvery Man JackBeauty & Personal Carecitric acid, benzyl alcohol, betaine, citric acid, cocamidopropyl betaine, decyl glucoside, panthenol, glycerin, hexylene glycol, menthol, phenoxyethanol, glycol stearate2024-11-29 10:47:42
Formula 10.0.6 Deep Down Detox Ultra-Cleansing Mud Mask -- 3.4 fl ozFormula 10.0.6Beauty & Personal Careorange, cetearyl alcohol, cetyl alcohol, tocopherol, tocopherol, kaolin, methylparaben, phenoxyethanol, PEG-40 stearate, propylparaben, stearic acid2024-11-29 10:47:42
Giovanni 2chic Ultra-Volume Conditioner with Tangerine & Papaya Butter -- 8.5 fl ozGiovanniBeauty & Personal Carecitric acid, cetearyl alcohol, citric acid, panthenol, pro-vitamin B-5, glycerin, dimethicone, phenoxyethanol, glycol stearate, stearyl alcohol2024-11-29 10:47:42
Giovanni 2chic Ultra-Volume Shampoo with Tangerine & Papaya Butter -- 8.5 fl ozGiovanniBeauty & Personal Carecitric acid, beta-carotene, citric acid, decyl glucoside, dehydroacetic acid, panthenol, pro-vitamin B-5, phenoxyethanol, glycol stearate, sodium lauroyl sarcosinate2024-11-29 10:47:42
Giovanni Hemp Hydrating Shampoo -- 13.5 fl ozGiovanniBeauty & Personal Carecitric acid, benzyl alcohol, citric acid, cocamidopropyl betaine, decyl glucoside, dehydroacetic acid, glycerin, hemp, henna, phenoxyethanol, glycol stearate, sodium lauroyl sarcosinate, sodium cocoyl glutamate2024-11-29 10:47:42
Kiss My Face Holiday Hand Soap - Merry Berry -- 11 fl ozKiss My FaceHousehold Essentialsorange, citric acid, allantoin, citric acid, cocamidopropyl betaine, decyl glucoside, glycerin, phenoxyethanol, glycol stearate2024-11-29 10:47:42
Kiss My Face Kids Hand Soap Citrus -- 9 fl ozKiss My FaceBaby & Kids Productsorange, citric acid, allantoin, citric acid, cocamidopropyl betaine, decyl glucoside, glycerin, phenoxyethanol, glycol stearate2024-11-29 10:47:42
Kiss My Face Kids Hand Soap Fragrance Free -- 9 fl ozKiss My FaceBaby & Kids Productscitric acid, allantoin, citric acid, cocamidopropyl betaine, decyl glucoside, glycerin, phenoxyethanol, glycol stearate2024-11-29 10:47:42
Kiss My Face Moisturizing Hand Soap Olive & Aloe -- 9 fl ozKiss My FaceHousehold Essentialsorange, citric acid,, allantoin, cocamidopropyl betaine, vitamin e, decyl glucoside, vitamin e, glycerin, phenoxyethanol, glycol stearate, sodium benzoate2024-11-29 10:47:42
Kiss My Face Moisturizing Hand Soap Tea Tree -- 9 fl ozKiss My FaceHousehold Essentialsorange, citric acid, allantoin, citric acid, cocamidopropyl betaine, decyl glucoside, glycerin, phenoxyethanol, glycol stearate2024-11-29 10:47:42
Native Facial Cleanser Moisturizing Coconut & Vanilla -- 12 fl ozNativeBeauty & Personal Carecitric acid, citric acid, cocamidopropyl betaine, glycerin, niacinamide, glycol stearate, sodium lauroyl sarcosinate, sodium benzoate2024-11-29 10:47:42
Nubian Heritage Cruelty & Paraben-Free Raw Shea Butter Body Wash for Dry Skin -- 13 fl ozNubian HeritageBeauty & Personal CareCaprylyl Glycol, Citric Acid, Citric Acid, Tocopherol, Decyl Glucoside, Panthenol, Tocopherol, Glycerin, Glycol Stearate2024-11-29 10:47:42
Nubian Heritage Cruelty-Free Coconut Oil & Papaya Hydrating Body Wash Cleanser for Dry Skin -- 13 fl ozNubian HeritageBeauty & Personal CareCaprylyl Glycol, Tocopherol, Decyl Glucoside, Panthenol, Tocopherol, Glycerin, Glycol Stearate2024-11-29 10:47:42
Nubian Heritage Cruelty-Free Goats Milk & Chai Body Wash Cleanser with Shea Butter for All Skin -- 13 fl ozNubian HeritageBeauty & Personal CareTocopherol, Decyl Glucoside, Panthenol, Tocopherol, Glycerin, Glycol Stearate2024-11-29 10:47:42
Nubian Heritage Cruelty-Free Indian Hemp & Haitian Vetiver Body Wash Cleanser with Shea Butter -- 13 fl ozNubian HeritageBeauty & Personal CareTocopherol, Decyl Glucoside, Panthenol, Tocopherol, Glycerin, Hemp, Henna, Glycol Stearate2024-11-29 10:47:42
Pacifica Sea Foam Complete Face Wash -- 5 fl ozPacificaBeauty & Personal Carecitric acid, allantoin, tocopherol acetate, citric acid, cocamidopropyl betaine, decyl glucoside, panthenol, ethylhexylglycerin, glycerin, glycol stearate, sodium benzoate, sodium cocoyl glutamate2024-11-29 10:47:42
SheaMoisture Kids Shampoo Extra-Nourishing Mango & Carrot -- 24 fl ozSheaMoistureBaby & Kids Productsdecyl glucoside, panthenol, glycerin, glycol stearate2024-11-29 10:47:42
SheaMoisture Kids Shampoo Extra-Nourishing Mango & Carrot -- 8 fl ozSheaMoistureBaby & Kids Productsdecyl glucoside, panthenol, glycerin, glycol stearate2024-11-29 10:47:42
SheaMoisture Paraben-Free Curl & Shine Coconut & Hibiscus Shampoo for Curly Hair -- 13 fl ozSheaMoistureBeauty & Personal Carecaprylyl glycol, tocopherol, decyl glucoside, panthenol, tocopherol, glycerin, glycol stearate, sodium benzoate2024-11-29 10:47:42
SheaMoisture Raw Shea Butter Hydrating Body Wash for Dry Skin -- 13 fl ozSheaMoistureBeauty & Personal Carecaprylyl glycol, benzoic acid, palm, tocopherol, decyl glucoside, panthenol, triethyl citrate, tocopherol, glycerin, glycol stearate2024-11-29 10:47:42
SheaMoisture Sulfate-Free Manuka Honey & Mafura Oil Intense Hydration Shampoo for Dry Damaged Hair -- 13 fl ozSheaMoistureBeauty & Personal Carecaprylyl glycol, tocopherol, decyl glucoside, panthenol, tocopherol, glycerin, glycol stearate2024-11-29 10:47:42
The Seaweed Bath Co Detox Body Wash - Orange Cedar -- 12 fl ozThe Seaweed Bath CoBeauty & Personal Carecitric acid, allantoin, citric acid, cocamidopropyl betaine, decyl glucoside, gluconic acid, glycol stearate, montmorillonite, sodium benzoate2024-11-29 10:47:42
The Seaweed Bath Co Detox Body Wash - Rosemary Mint -- 12 fl ozThe Seaweed Bath CoBeauty & Personal Carecitric acid, allantoin, citric acid, cocamidopropyl betaine, decyl glucoside, gluconic acid, glycol stearate, montmorillonite, sodium benzoate2024-11-29 10:47:42
The Seaweed Bath Co Hydrate Body Wash - Citrus Vanilla -- 12 fl ozThe Seaweed Bath CoBeauty & Personal Careorange, citric acid, allantoin, chlorophyll, citric acid, cocamidopropyl betaine, decyl glucoside, gluconic acid, glycol stearate, sodium benzoate, sodium cocoyl glutamate, vanilla2024-11-29 10:47:42
The Seaweed Bath Co Hydrate Body Wash - Eucalyptus Peppermint -- 12 fl ozThe Seaweed Bath CoBeauty & Personal Carecitric acid, allantoin, chlorophyll, citric acid, decyl glucoside, gluconic acid, glycol stearate, sodium benzoate2024-11-29 10:47:42
The Seaweed Bath Co Hydrate Body Wash - Unscented -- 12 fl ozThe Seaweed Bath CoBeauty & Personal Carecitric acid, allantoin, chlorophyll, citric acid, cocamidopropyl betaine, decyl glucoside, gluconic acid, glycol stearate, sodium benzoate, sodium cocoyl glutamate2024-11-29 10:47:42
Vitabath Body Cream Cucumber & White Tea -- 8 ozVitabathBeauty & Personal Careascorbic acid, BHT, cetyl alcohol, tocopherol, panthenol, diazolidinyl urea, disodium EDTA, tocopherol, glycerin, dimethicone, niacinamide, PEG-150 stearate, retinyl palmitate, stearic acid, triethanolamine2024-11-29 10:47:42
Vitabath Body Cream Lavender Chamomile -- 8 fl ozVitabathBeauty & Personal Careascorbic acid, BHT, cetyl alcohol, tocopherol, panthenol, diazolidinyl urea, disodium EDTA, tocopherol, glycerin, dimethicone, niacinamide, PEG-150 stearate, retinyl palmitate, stearic acid, triethanolamine2024-11-29 10:47:42
Zion Health Adama Ancient Minerals Shampoo Regenerate Geranium Rose -- 16 fl ozZion HealthBeauty & Personal Caregeranium, citric acid, citric acid, cocamidopropyl betaine, panthenol, ethyl hexyl glycerin, glycerin, vitamin b5, glycol stearate2024-11-29 10:47:42
Zion Health Adama Ancient Minerals Shampoo White Coconut -- 16 fl ozZion HealthBeauty & Personal Carecitric acid, citric acid, cocamidopropyl betaine, panthenol, ethyl hexyl glycerin, glycerin, Vitamin B5, glycol stearate, sodium benzoate2024-11-29 10:47:42
Zion Health Ancient Minerals Conditioner White Coconut -- 16 fl ozZion HealthBeauty & Personal Carecitric acid, citric acid, cocamidopropyl betaine, ethylhexyl-glycerin, glycerin, vitamin B5, glycol stearate, sodium benzoate2024-11-29 10:47:42

Roles (3)

RoleDescription
nonionic surfactantA surfactant with an uncharged hydrophilic headgroup.
emulsifierThe chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability.
plasticiserAny compound that is used as an additive to increase the plasticity or fluidity of a substance, particularly but not exclusively to synthetic polymers.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
octadecanoate esterA fatty acid ester obtained by condensation of the carboxy group of stearic acid with the hydroxy group of any alcohol or phenol.
long-chain primary fatty alcoholA long-chain fatty alcohol in which the hydroxy group is attached to a methylene (CH2) group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
TDP1 proteinHomo sapiens (human)Potency2.66090.000811.382244.6684AID686979
estrogen nuclear receptor alphaHomo sapiens (human)Potency9.43920.000229.305416,493.5996AID743079
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency35.48130.009610.525035.4813AID1479145
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Ceullar Components (1)

Processvia Protein(s)Taxonomy
virion membraneSpike glycoproteinSevere acute respiratory syndrome-related coronavirus
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's3 (60.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 33.48

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index33.48 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index44.40 (26.88)
Search Engine Supply Index2.41 (0.95)

This Compound (33.48)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
stearic acid
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.		2.2510long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite
12-hydroxy stearic acid
12-hydroxy stearic acid: structure in first source. 12-hydroxyoctadecanoic acid : A hydroxy fatty acid that is stearic acid bearing a hydroxy substituent at position 12.		2.2510hydroxyoctadecanoic acid;
secondary alcohol		bacterial xenobiotic metabolite;
plant metabolite
stearates
Stearates: Salts and esters of the 18-carbon saturated, monocarboxylic acid--stearic acid.		2.2510
ConditionIndicatedRelationship StrengthStudiesTrials
Varices
[description not available]		01.9710
Varicose Veins
Enlarged and tortuous VEINS.		01.9710
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