Page last updated: 2024-12-06

2-methyl-1,3-propanediol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Occurs in Manufacturing Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

2-Methyl-1,3-propanediol (MPD) is a colorless, viscous liquid with a sweet odor. It is a chiral compound with two enantiomers. MPD is a versatile chemical that finds applications in various industries, including pharmaceuticals, cosmetics, and polymers. It is used as a solvent, plasticizer, and intermediate in the synthesis of other chemicals. MPD is also being investigated for its potential use as a biofuel.
MPD can be synthesized by various methods, including the hydrogenation of methyl methacrylate, the aldol condensation of formaldehyde and acetone, and the reaction of propylene oxide with formaldehyde.
MPD is generally considered to be non-toxic and biodegradable. However, some studies have shown that it can cause skin and eye irritation. MPD is also flammable.
MPD is studied for its potential use as a sustainable alternative to traditional fuels. It is also being investigated for its use in the synthesis of new polymers and pharmaceuticals.'

Cross-References

ID SourceID
PubMed CID75103
CHEMBL ID3183047
MeSH IDM0402110

Synonyms (39)

Synonym
2-methyl-1,3-propanediol
propane-1,3-diol, 2-methyl-
inchi=1/c4h10o2/c1-4(2-5)3-6/h4-6h,2-3h2,1h3
qwgrwmmwndwrqn-uhfffaoysa-
2163-42-0
2-methylpropane-1,3-diol
2-methyl-1,3-propanediol, 99%
1,3-propanediol, 2-methyl-
1,3-dihydroxy-2-methylpropane
M1114
EN300-85197
NCGC00248505-01
cas-2163-42-0
tox21_200047
NCGC00257601-01
dtxsid3029231 ,
dtxcid609231
n8f53b3r4r ,
methylpropanediol
hsdb 7267
unii-n8f53b3r4r
FT-0612887
.beta.-hydroxyisobutanol
methylpropanediol [inci]
1,3-propanediol, 2-methyl- [hsdb]
AKOS015856381
2-methypropan-1,3-diol
2-methyl-propane-1,3-diol
2-methyl-1,3-propandiol
2-methylpropan-1,3-diol
mp diol glycol
CHEMBL3183047
F0001-0772
mfcd00082586
CS-0021060
D71170
Q27284705
SB83782
1,3-isobutanediol
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Occurs in Manufacturing (6 Product(s))

Product Categories

Product CategoryProducts
Beauty & Personal Care6

Products

ProductBrandCategoryCompounds Matched from IngredientsDate Retrieved
BioRepublic Skincare Lip Mask -- 0.17 fl ozBioRepublic SkincareBeauty & Personal Carecaprylyl glycol, butylene glycol, methylpropanediol, citric acid, ascorbyl palmitate, arginine, bisabolol, carbomer, citric acid, panthenol, hydroxyphenyl propamidobenzoic acid, glycerin, phenoxyethanol, propanediol, sodium citrate, squalane2024-11-29 10:47:42
Dead Sea Naturals Skincare Starter Kit -- 1 KitDead Sea NaturalsBeauty & Personal Carecaprylyl glycol, butylene glycol, aminomethyl propanol, methylpropanediol, citric acid, ascorbyl palmitate, alanine, allantoin, ascorbyl glucoside, ascorbic acid, bisabolol, cetearyl alcohol, cetyl alcohol, cetyl palmitate, chlorphenesin, citric acid, cocamidopropyl betaine, tocopherol, panthenol, pro vitamin B5, ethylhexylglycerin, farnesol, tocopherol, vitamin E, glyceryl stearate, glycerin, glycine, dimethicone, hexyl cinnamal, hydroxyethylcellulose, pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, isopropyl myristate, kaolin, lactic acid, linalool, niacinamide, phenoxyethanol, peg-40 stearate, propylene glycol, salicylic acid, beta-sitosterol, sodium benzoate, sodium citrate, sodium hydroxide, sodium lactate, squalene, stearyl alcohol, trehalose, urea, zinc oxide2024-11-29 10:47:42
Eucerin Skin Calming Daily Moisturizing Creme Fragrance Free -- 14 ozEucerinBeauty & Personal Caremethylpropanediol, benzyl alcohol, carbomer, cetyl alcohol, cetyl palmitate, glyceryl stearate, glycerin, dimethicone, octyldodecanol, phenoxyethanol, piroctone olamine, PEG-40 stearate2024-11-29 10:47:42
Hempz Triple Moisture Herbal Whipped Body Creme -- 17 fl ozHempzBeauty & Personal Careaminomethyl propanol, methylpropanediol, amyl cinnamal, ascorbic acid, benzyl benzoate, carbomer, cetearyl alcohol, tocopherol, cyclopentasiloxane, tocopherol, glycerin, dimethicone, hexyl cinnamal, limonene, linalool, trisodium ethylenediamine disuccinate, phenoxyethanol, propanediol, retinyl palmitate2024-11-29 10:47:42
Kiss My Face Self Tanning Drops -- 1 fl ozKiss My FaceBeauty & Personal Caremethylpropanediol, orange, citric acid, citric acid, dihydroxyacetone, glycerin, phenoxyethanol2024-11-29 10:47:42
Kiss My Face Self Tanning Firming Mousse -- 3 fl ozKiss My FaceBeauty & Personal Caremethylpropanediol, citric acid, caffeine, citric acid, cocamidopropyl betaine, dihydroxyacetone, erythrulose, glycerin, phenoxyethanol, xylitol2024-11-29 10:47:42

Protein Targets (2)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
activating transcription factor 6Homo sapiens (human)Potency58.53620.143427.612159.8106AID1159516
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency19.44390.000323.4451159.6830AID743067
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 46.62

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index46.62 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index66.45 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (46.62)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]