Page last updated: 2024-09-27

Job Syndrome

Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.

Synonyms(1)

Synonym
Job Syndrome

Research

Studies (105)

TimeframeStudies, This Condition (%)All Conditions %
pre-199011 (10.48)23.3326
1990's24 (22.86)12.5806
2000's32 (30.48)18.1394
2010's27 (25.71)28.8240
2020's11 (10.48)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carnitine0low10
salicylic acid0low10
histamine0low30
azathioprine0low10
busulfan0low10
cimetidine0low10
dilazep0low10
fentanyl0low10
fluconazole0low30
flucytosine0low10
isoflurane0low10
metoclopramide0low10
midazolam0low10
entinostat0low10
norfloxacin0low10
ofloxacin0low10
succinylcholine0low10
sulfamethoxazole0low10
trimethoprim0low10
prednisolone0low30
reserpine0low10
prednisone0medium61
tubocurarine0low10
tyrosine0low10
adenosine monophosphate0low10
methicillin0low10
methylprednisolone0low20
penicillin v0low10
fusarium0low10
luminol0low10
erythromycin0low10
vancomycin0low10
gold0low10
levamisole0medium31
cromolyn sodium0low20
tetradecanoylphorbol acetate0low20
phosphotyrosine0low20
triamcinolone0low10
cefazolin0low20
tobramycin0low10
fialuridine0low10
cefaclor anhydrous0low10
itraconazole0low20
glucose, (beta-d)-isomer0low10
iopamidol0low10
cephalosporin c0low10
triazoles0low10
voriconazole0low20
suplatast tosilate0low10
oxazolidin-2-one0low10
glycidyl nitrate0low10
pyridinoline0low10
methotrexate0low10
levofloxacin0low10
trimethoprim, sulfamethoxazole drug combination0low30
epiglucan0low10
inositol 3-phosphate0low20
linezolid0low20
n-formylmethionine leucyl-phenylalanine0low20
posaconazole0low10
thiopental0low10
nnd 5020low10
lithium0low10
ovalbumin0low20
dinoprostone0low10
amphotericin b0low60
geranylgeranylacetone0low10
cefepime0low10
mocetinostat0low30
treosulfan0low10
pituitrin0low10
arabinofuranosyluracil0low10
cromolyn sodium0low10
jaw0low10
interleukin-80low50
tuftsin0low10
minocycline0low10
warfarin0low10
epidermal growth factor0low10
pf 35126760low10
transforming growth factor beta0low30
caseins0low10
cyclosporine0low50
lactoferrin0low10
technetium tc 99m medronate0low10
muramidase0low10
acyclovir0low10
rifampin0low10
ganciclovir0low10
inosine pranobex0low10
lipoteichoic acid0low10
eye0low10

Protein Targets (853)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein100010
Chain B, HADH2 protein100010
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Ferritin light chain5005
Thymidine kinase 0202
thioredoxin reductase160016
phosphopantetheinyl transferase9009
GLS protein9009
TDP1 protein220022
Smad33003
thyroid stimulating hormone receptor9009
EWS/FLI fusion protein170017
arylsulfatase A6006
euchromatic histone-lysine N-methyltransferase 2200020
activating transcription factor 66006
Histone H2A.x4004
Bloom syndrome protein isoform 17007
hemoglobin subunit beta3003
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
lamin isoform A-delta10200020
Solute carrier family 22 member 1 06010
ATP-binding cassette sub-family C member 3027027
Multidrug resistance-associated protein 4028031
Solute carrier family 22 member 60405
Bile salt export pump010010
Bile salt export pump036036
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0103
POU domain, class 2, transcription factor 20002
Cytochrome P450 2C9 016017
Cytochrome P450 2J20909
Disintegrin and metalloproteinase domain-containing protein 172002
Purine nucleoside phosphorylase0022
Solute carrier family 22 member 60307
Thymidine kinase 0101
Solute carrier family 22 member 80509
Canalicular multispecific organic anion transporter 1028028
Thymidine kinase0101
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
RAR-related orphan receptor gamma160016
AR protein230023
regulator of G-protein signaling 46006
glucocorticoid receptor [Homo sapiens]210021
estrogen-related nuclear receptor alpha190019
v-jun sarcoma virus 17 oncogene homolog (avian)4004
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
Mitogen-activated protein kinase kinase kinase 70011
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20012
Transient receptor potential cation channel subfamily M member 20101
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0203
Fructose-1,6-bisphosphatase 10101
2-dehydropantoate 2-reductase0112
Inosine-5'-monophosphate dehydrogenase0101
Proto-oncogene tyrosine-protein kinase Src0102
Amine oxidase [flavin-containing] B0202
5'-nucleotidase0001
Choline O-acetyltransferase0101
Adenylate kinase 2, mitochondrial0102
GTP:AMP phosphotransferase AK3, mitochondrial0001
Adenosine receptor A10011
Adenylate kinase isoenzyme 1 0102
P2Y purinoceptor 20011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
5'-AMP-activated protein kinase subunit gamma-10023
5'-AMP-activated protein kinase catalytic subunit alpha-20012
Adenylate kinase 2, mitochondrial0001
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10023
Adenosine deaminase-like protein0001
Protease 0325
P2Y purinoceptor 110011
Histamine H3 receptor0101
5'-AMP-activated protein kinase subunit gamma-30012
5'-AMP-activated protein kinase subunit gamma-20012
5'-AMP-activated protein kinase subunit beta-10023
ATP-dependent phosphofructokinase8008
estrogen nuclear receptor alpha300030
peripheral myelin protein 22110011
histone acetyltransferase KAT2A isoform 19009
Aminoglycoside 3'-phosphotransferase 0001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE100010
Chain A, Beta-lactamase6006
Chain A, 2-oxoglutarate Oxygenase100010
Beta-lactamase 0001
Beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0002
apical membrane antigen 1, AMA15005
Beta-lactamase 0001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
DNA polymerase eta isoform 14004
DNA polymerase iota isoform a (long)100010
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
DNA polymerase kappa isoform 15005
Beta-lactamase SHV-10001
Beta-lactamase SHV-10002
Beta-lactamase0002
Kappa-type opioid receptor0204
Solute carrier family 15 member 10707
Solute carrier family 15 member 10101
B2 metallo-beta-lactamase 0002
Solute carrier family 15 member 20404
Beta-lactamase 0001
Beta-lactamase 0002
Solute carrier family 15 member 20404
Beta-lactamase 0001
Beta-lactamase 0002
Chain A, Cruzipain3003
interleukin 87007
farnesoid X nuclear receptor9009
peroxisome proliferator-activated receptor delta7007
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
tumor necrosis factor2002
vitamin D3 receptor isoform VDRA8008
nuclear factor erythroid 2-related factor 2 isoform 1150015
Cytochrome P450 1A20203
Cytochrome P450 3A4010112
Cytochrome P450 2D60607
Cytochrome P450 2C190506
Nuclear receptor ROR-gamma4004
Potassium voltage-gated channel subfamily H member 2010010
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20405
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
acetylcholinesterase6006
SMAD family member 26006
ATAD5 protein, partial7007
Fumarate hydratase4004
SMAD family member 36006
GLI family zinc finger 3160016
Microtubule-associated protein tau7007
thioredoxin glutathione reductase4004
nuclear receptor subfamily 1, group I, member 3100010
retinoic acid nuclear receptor alpha variant 1140014
retinoid X nuclear receptor alpha170017
pregnane X nuclear receptor180018
G130013
polyprotein4004
P531001
peroxisome proliferator activated receptor gamma7007
IDH14004
aryl hydrocarbon receptor8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
thyroid stimulating hormone receptor5005
peripheral myelin protein 22 isoform 13003
cellular tumor antigen p53 isoform a2002
thyroid hormone receptor beta isoform 2150015
heat shock protein beta-13003
geminin200020
survival motor neuron protein isoform d6006
cytochrome P450 3A4 isoform 18008
M-phase phosphoprotein 84004
muscleblind-like protein 1 isoform 15005
muscarinic acetylcholine receptor M15005
Gamma-aminobutyric acid receptor subunit pi84012
Voltage-dependent calcium channel gamma-2 subunit8008
Interferon beta170017
HLA class I histocompatibility antigen, B alpha chain 130013
Cellular tumor antigen p53140014
Gamma-aminobutyric acid receptor subunit beta-184012
Gamma-aminobutyric acid receptor subunit delta84012
Gamma-aminobutyric acid receptor subunit gamma-284012
Glutamate receptor 28008
Gamma-aminobutyric acid receptor subunit alpha-584012
Gamma-aminobutyric acid receptor subunit alpha-384012
Gamma-aminobutyric acid receptor subunit gamma-184012
Gamma-aminobutyric acid receptor subunit alpha-284012
Gamma-aminobutyric acid receptor subunit alpha-484012
Gamma-aminobutyric acid receptor subunit gamma-384012
Gamma-aminobutyric acid receptor subunit alpha-684012
Gamma-aminobutyric acid receptor subunit alpha-184012
Gamma-aminobutyric acid receptor subunit beta-384012
Gamma-aminobutyric acid receptor subunit beta-284012
GABA theta subunit84012
Inositol hexakisphosphate kinase 1130013
ATPase family AAA domain-containing protein 57007
Ataxin-27007
Gamma-aminobutyric acid receptor subunit epsilon84012
Protein-arginine deiminase type-40606
cytochrome P450 2C9, partial130013
Chain A, JmjC domain-containing histone demethylation protein 3A5005
15-lipoxygenase, partial4004
aldehyde dehydrogenase 1 family, member A1150015
cytochrome P450 family 3 subfamily A polypeptide 4130013
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
lethal factor (plasmid)3003
Matrix metalloproteinase-90202
Solute carrier family 22 member 50001
Solute carrier family 22 member 50102
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
bromodomain adjacent to zinc finger domain 2B4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
importin subunit beta-1 isoform 14004
serine/threonine-protein kinase PLK13003
snurportin-14004
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10101
streptokinase A precursor0055
Estrogen receptor0022
Estrogen receptor beta0022
Luciferase2002
cytochrome P450 2D69009
Solute carrier family 22 member 110204
Solute carrier family 22 member 80303
Beta-lactamase 0001
Beta-lactamase 0102
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase TEM0102
Beta-lactamase0001
Metallo-beta-lactamase VIM-130001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0002
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase class B VIM-2 0002
Beta-lactamase VIM-1 0001
progesterone receptor100010
alpha-galactosidase2002
cytochrome P450 2C19 precursor3003
Solute carrier family 22 member 10101
Solute carrier family 22 member 20306
Solute carrier family 22 member 20101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
ATP-dependent translocase ABCB10606
ATP-dependent translocase ABCB10809
Potassium-transporting ATPase alpha chain 10101
ATP-dependent translocase ABCB10606
Histamine H2 receptor0325
Histamine H1 receptor0145
Histamine H2 receptor2226
Potassium-transporting ATPase subunit beta0101
Aldehyde oxidase0101
Solute carrier family 22 member 10405
Multidrug and toxin extrusion protein 20202
Multidrug and toxin extrusion protein 10404
Histamine H4 receptor0224
Solute carrier family 22 member 20304
Solute carrier family 22 member 40101
Solute carrier family 22 member 80303
Beta-lactamase OXA-70002
Efflux transporter 0101
Beta-lactamase 0101
Alkaline phosphatase, germ cell type0101
G protein-coupled receptor GPR350011
G-protein coupled receptor 350011
G-protein coupled receptor 350011
USP1 protein, partial7007
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
cytochrome P450 2C9 precursor1001
potassium voltage-gated channel subfamily H member 2 isoform d5005
mitogen-activated protein kinase 14004
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Multidrug resistance-associated protein 50101
Equilibrative nucleoside transporter 20101
Liver carboxylesterase 10001
Spike glycoprotein7007
Inositol monophosphatase 11001
Equilibrative nucleoside transporter 10101
prostaglandin E2 receptor EP2 subtype1001
Solute carrier organic anion transporter family member 1A50001
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 70002
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
Histone deacetylase 80101
PPM1D protein4004
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
tyrosine-protein kinase Yes1001
Histone deacetylase 30516
Bromodomain-containing protein 40101
Leukotriene A-4 hydrolase0202
Androgen receptor0303
Tissue factor0101
Histone deacetylase 40314
Histone deacetylase 10527
Histone deacetylase-like amidohydrolase0202
Histone deacetylase 70314
Histone deacetylase 20527
Polyamine deacetylase HDAC100213
Histone deacetylase 11 0314
NAD-dependent protein deacetylase sirtuin-10101
Histone deacetylase 80314
Histone deacetylase 60314
Histone deacetylase 90213
Histone deacetylase 50314
Histone deacetylase 0101
Nuclear receptor corepressor 20303
Motilin receptor0011
acid sphingomyelinase2002
low molecular weight phosphotyrosine protein phosphatase isoform c0101
Motilin receptor0112
Rap guanine nucleotide exchange factor 33003
30S ribosomal protein S60213
30S ribosomal protein S70213
50S ribosomal protein L150213
Albumin0167
60 kDa chaperonin0101
50S ribosomal protein L100213
50S ribosomal protein L110213
50S ribosomal protein L7/L120213
50S ribosomal protein L190213
50S ribosomal protein L10213
50S ribosomal protein L200213
50S ribosomal protein L270213
50S ribosomal protein L280213
50S ribosomal protein L290213
50S ribosomal protein L310213
50S ribosomal protein L31 type B0213
50S ribosomal protein L320213
50S ribosomal protein L330213
50S ribosomal protein L340213
50S ribosomal protein L350213
50S ribosomal protein L360213
30S ribosomal protein S100213
30S ribosomal protein S110213
30S ribosomal protein S120213
30S ribosomal protein S130213
30S ribosomal protein S160213
30S ribosomal protein S180213
30S ribosomal protein S190213
30S ribosomal protein S200213
30S ribosomal protein S20213
30S ribosomal protein S30213
30S ribosomal protein S40213
30S ribosomal protein S50213
30S ribosomal protein S80213
30S ribosomal protein S90213
50S ribosomal protein L130213
50S ribosomal protein L140213
50S ribosomal protein L160213
50S ribosomal protein L230213
30S ribosomal protein S150213
50S ribosomal protein L170213
50S ribosomal protein L210213
50S ribosomal protein L300213
50S ribosomal protein L60213
30S ribosomal protein S140213
30S ribosomal protein S170213
30S ribosomal protein S10213
50S ribosomal protein L180213
60 kDa heat shock protein, mitochondrial0303
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0101
50S ribosomal protein L20213
50S ribosomal protein L30213
50S ribosomal protein L240213
50S ribosomal protein L40213
50S ribosomal protein L220213
10 kDa heat shock protein, mitochondrial0303
50S ribosomal protein L50213
30S ribosomal protein S210213
50S ribosomal protein L250213
Cytochrome P450 1B10101
Thiosulfate sulfurtransferase0303
Lanosterol 14-alpha demethylase0314
50S ribosomal protein L36 20213
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Nuclear receptor subfamily 1 group I member 20033
D(2) dopamine receptor0303
Amine oxidase [flavin-containing] A0303
D(4) dopamine receptor0101
Amine oxidase [flavin-containing] B0202
Delta-type opioid receptor0202
Delta-type opioid receptor0303
Mu-type opioid receptor0314
Kappa-type opioid receptor0202
Histamine H1 receptor0325
Mu-type opioid receptor0415
D(3) dopamine receptor0303
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
Mu-type opioid receptor0101
Mu-type opioid receptor0303
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10101
Thymidine kinase0001
Chain A, BCL-2-RELATED PROTEIN A10011
unnamed protein product0101
chromobox protein homolog 16006
transcriptional regulator ERG isoform 32002
heat shock protein HSP 90-alpha isoform 20001
bcl-2-like protein 11 isoform 10011
Chymotrypsinogen A0202
Beta-lactamase0101
Steroid 17-alpha-hydroxylase/17,20 lyase0202
Heme oxygenase 1 0101
Lanosterol 14-alpha demethylase0134
Aromatase0202
Cytochrome P450 11B1, mitochondrial0202
Cytochrome P450 11B2, mitochondrial0202
Heme oxygenase 20101
Malate dehydrogenase, cytoplasmic0101
Cytochrome P450 1440033
Steroid C26-monooxygenase0033
Steroid C26-monooxygenase0033
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0011
TAR DNA-binding protein 432002
Sterol 14-alpha demethylase0033
Sterol 14-alpha demethylase0224
14-alpha sterol demethylase 0033
heat shock protein 90, putative0001
likely tRNA 2'-phosphotransferase0101
Skn7p0001
nonstructural protein 13003
heat shock protein 900011
calcineurin A1, putative0011
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
endonuclease IV3003
ClpP2002
NFKB1 protein, partial3003
Transitional endoplasmic reticulum ATPase0101
Glycogen phosphorylase, muscle form0101
Asialoglycoprotein receptor 10112
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
GALC protein2002
transforming acidic coiled-coil-containing protein 30001
Carbonic anhydrase 120103
Solute carrier family 22 member 30102
Carbonic anhydrase 10204
Carbonic anhydrase 20216
Plasma kallikrein0002
Carbonic anhydrase 30103
Macrophage migration inhibitory factor0202
Carbonic anhydrase 40103
Carbonic anhydrase 60103
Adenosine receptor A10002
5-hydroxytryptamine receptor 1D0001
Adenosine receptor A2a0002
Histamine H1 receptor0213
Metabotropic glutamate receptor 50213
Carbonic anhydrase 5A, mitochondrial0103
Glutamate receptor ionotropic, NMDA 1 0002
Carbonic anhydrase0002
Carbonic anhydrase 70103
Carbonic anhydrase0003
Histamine H3 receptor0101
Glutamate receptor ionotropic, NMDA 2A 0002
Glutamate receptor ionotropic, NMDA 2B0002
Glutamate receptor ionotropic, NMDA 2C0002
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 90103
Carbonic anhydrase 0003
Carbonic anhydrase-like protein, putative0002
Carbonic anhydrase0003
Carbonic anhydrase0003
Glutamate receptor ionotropic, NMDA 2D0002
Carbonic anhydrase 0003
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130001
Glutamate receptor ionotropic, NMDA 3B0002
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 40001
Carbonic anhydrase 150103
Carbonic anhydrase 130102
Histamine H3 receptor0101
Carboxylic ester hydrolase 0001
Glutamate receptor ionotropic, NMDA 3A0002
Carbonic anhydrase 140103
Carbonic anhydrase 5B, mitochondrial0103
Histamine H3 receptor0123
nuclear receptor subfamily 1, group I, member 23003
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
hypoxia-inducible factor 1 alpha subunit3003
estrogen receptor 2 (ER beta)8008
dopamine D1 receptor3003
flap endonuclease 14004
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Phospholipase A-2-activating protein0101
Replicase polyprotein 1ab0101
CAAX prenyl protease 2 isoform 20001
DNA polymerase beta3003
Tubulin beta-4A chain0101
Tubulin beta chain0101
Tubulin alpha-3C chain0101
Tubulin alpha-1B chain0101
Tubulin alpha-4A chain0101
Tubulin beta-4B chain0101
Fatty-acid amide hydrolase 10202
DNA gyrase subunit A0304
DNA primase0101
Tubulin beta-3 chain0101
Tubulin beta-2A chain0101
Tubulin beta-8 chain0101
Tubulin alpha-3E chain0101
Tubulin alpha-1A chain0101
Tubulin alpha-1C chain0101
Tubulin beta-6 chain0101
Tubulin beta-2B chain0101
Tubulin beta-1 chain0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
DNA gyrase subunit A0304
DNA gyrase subunit B0304
Prostaglandin G/H synthase 10202
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Renin0101
NEDD8-activating enzyme E1 regulatory subunit isoform a0101
NEDD8-conjugating enzyme Ubc120101
GTP-binding nuclear protein Ran isoform 12002
Queuine tRNA-ribosyltransferase0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
67.9K protein2002
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
nuclear factor erythroid 2-related factor 2 isoform 27007
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor2002
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0405
Dihydrofolate reductase0304
Dihydrofolate reductase 0202
Dihydrofolate reductase0303
Dihydrofolate reductase0101
Dihydrofolate reductase0405
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0303
Integrin beta-31001
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Thymidylate synthase0202
Integrin alpha-IIb1001
5-hydroxytryptamine receptor 2C0203
High mobility group protein B10022
Dihydrofolate reductase0303
Thymidylate synthase0202
Dihydrofolate reductase0426
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0404
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0506
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0202
Caspase-72002
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0202
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0203
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0303
Dihydrofolate reductase0203
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30204
Glucocorticoid receptor08215
Glycine receptor subunit alpha-10808
Androgen receptor0303
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Nuclear receptor subfamily 1 group I member 20011
5-hydroxytryptamine receptor 3E0011
cytochrome P450 2D6 isoform 11001
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 40202
5-hydroxytryptamine receptor 3B0011
Albumin0022
Myeloperoxidase0101
Alpha-2A adrenergic receptor0303
Alpha-1B adrenergic receptor0202
D0101
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0101
Alpha-2B adrenergic receptor0202
D(2) dopamine receptor0101
Alpha-2C adrenergic receptor0202
Acetylcholinesterase0202
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 3A0101
D(1B) dopamine receptor0101
5-hydroxytryptamine receptor 2A0303
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
D(4) dopamine receptor0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0202
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 70202
D(2) dopamine receptor0202
Lactoperoxidase0101
5-hydroxytryptamine receptor 4 0102
5-hydroxytryptamine receptor 3D0011
5-hydroxytryptamine receptor 3C0011
5-hydroxytryptamine receptor 3B0101
5-hydroxytryptamine receptor 3B0202
Translocator protein0101
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 1A40101
UDP-glucuronosyltransferase 2B10 0101
Stromelysin-10112
Matrilysin0101
Multidrug transporter MdfA0101
Protein mono-ADP-ribosyltransferase PARP150101
Nuclear receptor corepressor 10101
Integrin beta-10101
Integrin alpha-40101
Formyl peptide receptor-related sequence 10011
fMet-Leu-Phe receptor0224
N-formyl peptide receptor 20022
FML2_HUMAN 0011
huntingtin isoform 21001
neuropeptide S receptor isoform A2002
DNA topoisomerase 4 subunit A0101
Multidrug resistance protein MdtK0011
STE240001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
CAAX prenyl protease0001
Trypsin0001
DNA gyrase subunit B0203
Vpr1001
Rap guanine nucleotide exchange factor 41001
nuclear receptor ROR-gamma isoform 13003
Replicase polyprotein 1ab0101
Tyrosine-protein kinase Lck0001
Growth factor receptor-bound protein 20001
Tyrosine-protein phosphatase non-receptor type 110001
Sterol 14-alpha-demethylase0022
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
14-alpha sterol demethylase 0022
14-alpha sterol demethylase 0022
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Estrogen receptor beta0202
pregnane X receptor1001
glp-1 receptor, partial2002
Thrombopoietin1001
thyroid hormone receptor beta isoform a2002
nuclear factor NF-kappa-B p105 subunit isoform 11001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Quinolone resistance protein NorA0102
DNA topoisomerase 10101
Chromaffin granule amine transporter0101
Synaptic vesicular amine transporter0101
Synaptic vesicular amine transporter0213
Synaptic vesicular amine transporter0101
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 1A40101
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Cytochrome P450 2B60112
Arylacetamide deacetylase0102
Caspase-10101
Alpha-synuclein0101
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20101
Glutathione S-transferase omega-10101
Enoyl-[acyl-carrier-protein] reductase [NADH]0101
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 1B10203
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20103
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
Xanthine dehydrogenase/oxidase0101
Carbonic anhydrase0101
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Acetylcholinesterase0101
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Endothelin-1 receptor0101
Serine/threonine-protein kinase D30011
Protein kinase C gamma type0112
Protein kinase C beta type0112
Luciferin 4-monooxygenase0011
Protein kinase C alpha type0112
Beta-1 adrenergic receptor0101
Protein kinase C eta type0011
Protein kinase C iota type0011
Protein kinase C epsilon type0112
Protein kinase C theta type0011
Protein kinase C zeta type0011
Protein kinase C delta type0112
Serine/threonine-protein kinase D10011
Ras guanyl-releasing protein 30011
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Protein Rev 0011
procathepsin L isoform 1 preproprotein0101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0101
Dihydrofolate reductase 0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Tubulin--tyrosine ligase0101
Monocarboxylate transporter 100001
Taste receptor type 2 member 140001
Sodium-dependent serotonin transporter0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
Cholesterol 24-hydroxylase0213
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]