Albright Syndrome

Synonym
Albright-Mccune-Sternberg Syndrome
Albright Syndrome
Albright-Sternberg Syndrome
Albright's Disease
McCune-Albright Syndrome
Albright's Disease of Bone
Albright's Syndrome
Albright's Syndrome with Precocious Puberty
Fibrous Dysplasia with Pigmentary Skin Changes and Precocious Puberty
Polyostotic Fibrous Dysplasia

Excerpt	Reference
"The McCune-Albright syndrome is characterized by café au lait spots, fibrous dysplasia of bones, and sexual precocity."	( Barnes, K; Cutler, GB; Dwyer, A; Feuillan, PP; Foster, CM; Hench, KD; Loriaux, DL; Malley, JD; Pescovitz, OH; Shawker, T, 1986)
"A case of polyostotic fibrous dysplasia is presented in which the extent of bony lesions was defined on the results of the CT scan and bone scan with 99m Tc polyphosphate in addition to conventional radiography."	( Higashi, T; Iguchi, M; Kruglik, GD; Shimura, A, 1980)
"McCune-Albright syndrome is a rare disorder caused by a somatic, constitutively activating mutation in the gene (GNAS1) encoding the subunit of the signal transducing guanine nucleotide binding protein (G protein)."	( Dunkel, L; Kairemo, KJ; Verho, S, 1999)
"McCune-Albright syndrome is a rare genetic disorder consisting of skin and bone dysplasia and peripheral endocrinopathies."	( Bertelloni, S; Buzi, F; de Sanctis, C; Lala, R; Matarazzo, P; Rigon, F, 2000)
"McCune-Albright syndrome is a rare syndrome presenting with polyostotic dysplasia, cafe-au-lait spots and multiple endocrinopathies that is very often combined with precocious puberty."	( Jassoy, A; Lebek, S; Nagel, M; Zumkeller, W, 2001)
"McCune-Albright syndrome is characterized by café-au-lait spot, multiple endocrine hyperfunction, and polyostotic fibrous dysplasia."	( Ida, S; Imanishi, Y; Kikuchi, T; Michigami, T; Mori, I; Ohata, Y; Ozono, K; Satomura, K; Yamamoto, T, 2009)
"McCune-Albright syndrome is a rare syndrome, classically defined as the triad of precocious puberty, fibrous dysplasia of bone, and café au lait lesions."	( Bercaw-Pratt, JL; Dietrich, JE; Karaviti, L; Moorjani, TP; Santos, XM, 2012)
"McCune-Albright syndrome is a rare sporadic disease characterized by fibrous bone dysplasia, café-au-lait skin spots and variable hyperfunctional endocrinopathies."	( Dias, P; Gouveia, R; Lourenço, R; Oliveira, G; Sousa, AB, 2015)
"McCune Albright syndromeis a rare disorder that presents with multiple endocrine abnormalities."	( Asha, HS; Cherian, KE; Paul, TV; Rajan, R, 2019)
"McCune-Albright syndrome is a rare disorder characterized by fibrous dysplasia, café au lait skin spots, and hyperfunctioning endocrinopathies."	( Chen, S; Deng, K; Duan, L; Feng, F; Liang, Z; Lu, L; Pan, H; Wang, L; Wang, R; Xing, B; Yang, H; Yao, Y; You, H; Zhai, X; Zhu, H, 2021)
"McCune-Albright syndrome is a complex disorder encompassing multiple endocrinopathies."	( Al Zubeidi, H; Diaz-Thomas, A; Foster, C, 2022)
"McCune-Albright syndrome is characterized by the triad of fibrous dysplasia, café au lait skin pigmentation, and hyperfunctioning endocrinopathies."	( Apperley, LJ; Senniappan, S, 2023)

Excerpt	Reference
"In a 6 1/2-month-old girl with McCune-Albright syndrome, gonadotropin-independent isosexual precocity and recurrent ovarian cysts, the short-term effects of surgical therapy, cyproterone acetate (120 mg/m2/d), combined medroxyprogesterone acetate (10 mg/d), and spironolactone (50-75 mg/d) treatment, and testolactone (40 mg/kg/d) were evaluated sequentially."	( Hauffa, BP; Havers, W; Stolecke, H, 1987)
"A 12-year-old Japanese girl with polyostotic fibrous dysplasia and endocrine concomitants, was treated with elcatonin, a synthetic eel calcitonin analogue, 10 MRC unit/twice a week given by intramuscular injection."	( Harada, Y; Ishikawa, J; Ishitobi, K; Kishimoto, H; Maeyama, I; Morio, Y; Yamamoto, K, 1983)
"Six girls with McCune-Albright syndrome were treated for at least 2 months with the long-acting LHRH agonist D-Trp6-Pro9-NEt-LHRH, which previously was found to be an effective treatment for true precocious puberty."	( Comite, F; Cutler, GB; Foster, CM; Loriaux, DL; Pescovitz, OH; Ross, JL, 1984)
"Thirteen patients with McCune-Albright syndrome (MAS) and bone fibrous dysplasia (BFD) have been treated for 2-6 years with pamidronate, an aminobisphosphonate which inhibits osteoclastic function."	( Altare, F; Andreo, M; de Sanctis, C; Lala, R; Masi, G; Matarazzo, P, 2002)
"We report a case of polyostotic fibrous dysplasia in a three-year-old child who showed significant improvement in bone mineral density after treatment with oral alendronate."	( Khadilkar, AV; Khadilkar, VV; Maskati, GB, 2003)
"We describe a patient with polyostotic fibrous dysplasia, who had complained of persistent pain for more than 20 years, that was treated with oral alendronate alone."	( Ito, H; Kitagawa, Y; Tamai, K, 2004)
"We present a case of McCune-Albright syndrome revealed by a Cushing's syndrome treated by metyrapone."	( Azzabi, O; Ben Ammar, B; Ben Hariz, M; Ben Mrad, N; Halioui-Louhaichi, S; Maherzi, A; Nefzi, L, 2005)
"We report a case of McCune-Albright syndrome with CS treated with metyrapone for 30 months with prolonged remission after a 12-year follow-up."	( Azzabi, O; Dridi, Y; Fetni, I; Halioui-Louhaichi, S; Maherzi, A; Selmi, I; Siala, N, 2016)
"We report here on a child with McCune-Albright syndrome (FD in addition to hyperfunctioning endocrinopathies and skin hyperpigmentation) treated with cyclical intravenous infusions of pamidronate in which conventional radiography, contact microradiography, histology, and backscattered electron image analysis demonstrated that zebra lines formed only where bone was normal, were arrested at the boundary between FD-unaffected and FD-affected bone where bone is sclerotic, and were absent within the undermineralized FD bone."	( Boyde, A; Corsi, A; Ippolito, E; Riminucci, M; Robey, PG, 2017)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	54 (17.76)	23.3326
1990's	58 (19.08)	12.5806
2000's	107 (35.20)	18.1394
2010's	66 (21.71)	28.8240
2020's	19 (6.25)	9.53

Drug	Relationship Strength	Studies	Trials
chlorine	low	2	0
salicylic acid	low	3	0
dimethyl sulfoxide	low	1	0
glycerol	low	1	0
iodine	low	1	0
alendronate	low	6	0
aminoglutethimide	low	2	0
anastrozole	low	5	0
bicalutamide	low	1	0
pentetic acid	low	2	0
etidronate	low	2	0
flutamide	low	1	0
gabexate	low	1	0
isoproterenol	low	1	0
ketoconazole	low	4	0
letrozole	medium	7	1
metyrapone	low	7	0
pamidronate	medium	25	4
potassium iodide	low	1	0
propranolol	low	1	0
rolipram	low	1	0
risedronic acid	low	1	0
hydroxyproline	low	3	0
thyroxine	low	5	0
spironolactone	low	2	0
estrone	medium	5	1
dehydroepiandrosterone	low	1	0
triiodothyronine	low	6	0
alanine	low	1	0
glutamine	low	1	0
lysine	low	1	0
levodopa	low	1	0
edetic acid	low	1	0
androstenedione	low	2	0
17-alpha-hydroxyprogesterone	low	1	0
medroxyprogesterone acetate	low	3	0
tryptophan	low	1	0
arginine	medium	8	1
methylprednisolone	low	1	0
calcium gluconate	low	1	0
cyproterone acetate	low	5	0
limestone	low	1	0
medroxyprogesterone	low	3	0
calcium lactate	low	1	0
testolactone	low	8	0
megestrol	low	2	0
tantalum	low	1	0
technetium	low	5	0
titanium	low	2	0
gadolinium	low	3	0
tricalcium phosphate	low	2	0
fluorides	low	2	0
carbimazole	low	2	0
bromocriptine	low	7	0
gallium citrate	low	1	0
zidovudine	low	1	0
propiconazole	low	18	0
buserelin	low	1	0
cabergoline	low	4	0
fadrozole	low	1	0
triazoles	medium	10	1
fluorodeoxyglucose f18	low	9	0
zoledronic acid	low	4	0
nomegestrol acetate	low	1	0
pyridinoline	low	1	0
deoxypyridinoline	low	1	0
1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid	low	1	0
gadolinium 1,4,7,10-tetraazacyclododecane-n,n',n'',n'''-tetraacetate	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	4	0
proline	low	1	0
olpadronic acid	low	1	0
cortisone	low	1	0
inositol 3-phosphate	low	1	0
dactinomycin	low	1	0
bromochloroacetic acid	low	1	0
isomethyleugenol	low	1	0
leuprolide	low	4	0
propylthiouracil	low	1	0
methimazole	medium	1	1
tamoxifen	medium	8	2
17-ketosteroids	low	1	0
calcitriol	low	6	0
cholecalciferol	low	4	0
cyproterone	low	4	0
gallium	low	1	0
cysteine	low	1	0
phosphorus	low	9	0
gadolinium dtpa	low	3	0
ergoline	low	3	0
mart-1 antigen	low	1	0
acid phosphatase	low	1	0
jaw	low	3	0
(dtpa-phe(1))-octreotide	low	1	0
glucagon	low	1	0
technetium tc 99m sestamibi	low	1	0
bucladesine	low	1	0
trelstar	low	5	0
deslorelin	low	1	0
transforming growth factor beta	low	2	0
gallium ga 68 dotatate	low	1	0
technetium tc 99m medronate	low	22	0
guanosine diphosphate	low	2	0
guanosine triphosphate	low	1	0
guanosine 5'-o-(3-thiotriphosphate)	low	2	0
neopterin	low	1	0
dacarbazine	low	1	0
eye	low	2	0
leptin	low	2	0
tetrafluoroaluminate	low	2	0

Protein Targets (788)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
ATAD5 protein, partial	9	0	0	9
apical membrane antigen 1, AMA1	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	24	0	0	24
chromobox protein homolog 1	19	0	0	19
DNA polymerase iota isoform a (long)	12	0	0	12
geminin	26	0	0	26
lethal factor (plasmid)	4	0	1	5
botulinum neurotoxin type A	0	0	1	1
botulinum neurotoxin type F, BoNT/F	0	0	1	1
acetylcholinesterase	6	0	0	6
pregnane X receptor	7	0	0	7
SMAD family member 2	10	0	0	10
SMAD family member 3	10	0	0	10
TDP1 protein	28	0	0	28
GLI family zinc finger 3	26	0	0	26
Microtubule-associated protein tau	8	0	0	8
AR protein	30	0	0	30
progesterone receptor	19	0	0	19
glucocorticoid receptor [Homo sapiens]	25	0	0	25
retinoic acid nuclear receptor alpha variant 1	23	0	0	23
retinoid X nuclear receptor alpha	21	0	0	21
estrogen-related nuclear receptor alpha	28	0	0	28
farnesoid X nuclear receptor	14	0	0	14
pregnane X nuclear receptor	26	0	0	26
estrogen nuclear receptor alpha	38	0	0	38
G	11	0	0	11
vitamin D (1,25- dihydroxyvitamin D3) receptor	16	0	0	16
arylsulfatase A	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	20	0	0	20
activating transcription factor 6	11	0	0	11
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	27	0	0	27
survival motor neuron protein isoform d	10	0	0	10
histone acetyltransferase KAT2A isoform 1	6	0	0	6
lamin isoform A-delta10	22	0	0	22
Voltage-dependent calcium channel gamma-2 subunit	11	0	0	11
Interferon beta	14	0	0	14
HLA class I histocompatibility antigen, B alpha chain	11	0	0	11
Glucocorticoid receptor	0	15	2	17
Sex hormone-binding globulin	0	0	6	6
Glycine receptor subunit alpha-1	0	14	0	14
Corticosteroid-binding globulin	0	5	0	5
Adenosine receptor A3	0	5	1	6
Replicase polyprotein 1ab	0	1	1	2
Androgen receptor	0	23	0	24
Alpha-1B adrenergic receptor	0	7	1	8
Glutamate receptor 2	11	0	0	11
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
Mitogen-activated protein kinase 3	0	1	0	1
Alpha-1A adrenergic receptor	0	7	1	8
Sodium-dependent dopamine transporter	0	6	0	6
TAR DNA-binding protein 43	6	0	0	6
Inositol hexakisphosphate kinase 1	11	0	0	11
cytochrome P450 2C9, partial	11	0	0	11
ATP-dependent phosphofructokinase	11	0	0	11
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	11	0	0	11
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	6	0	0	6
Carbonic anhydrase 1	0	6	0	10
Carbonic anhydrase 2	0	7	0	11
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	1	5
Proton-coupled amino acid transporter 1	0	3	0	3
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	1
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	6	0	7
Farnesyl pyrophosphate synthase	0	8	0	8
Acetylcholinesterase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	3	0	3
Farnesyl pyrophosphate synthase	0	6	0	6
Farnesyl pyrophosphate synthase	0	3	0	3
thioredoxin reductase	16	0	0	16
cytochrome P450 family 3 subfamily A polypeptide 4	16	0	0	16
IDH1	8	0	0	8
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	9	0	0	9
peripheral myelin protein 22 isoform 1	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	5	0	0	5
transcriptional regulator ERG isoform 3	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
cytochrome P450 3A4 isoform 1	12	0	0	12
Gamma-aminobutyric acid receptor subunit pi	12	2	2	16
ATP-binding cassette sub-family C member 3	0	17	0	17
Multidrug resistance-associated protein 4	0	17	0	17
Sterol O-acyltransferase 1	0	1	0	1
Bile salt export pump	0	26	0	26
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Triosephosphate isomerase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	5	0	5
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Aromatase	0	15	0	21
Gamma-aminobutyric acid receptor subunit beta-1	12	2	2	16
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	12	2	2	16
Gamma-aminobutyric acid receptor subunit gamma-2	12	2	2	16
Gamma-aminobutyric acid receptor subunit alpha-5	12	2	2	16
Gamma-aminobutyric acid receptor subunit alpha-3	12	2	2	16
Aromatase	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	12	2	2	16
Gamma-aminobutyric acid receptor subunit alpha-2	12	2	2	16
Thromboxane-A synthase	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	12	2	2	16
Gamma-aminobutyric acid receptor subunit gamma-3	12	2	2	16
Cytochrome P450 11B2, mitochondrial	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	12	2	2	16
Delta-type opioid receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	12	2	2	16
Gamma-aminobutyric acid receptor subunit beta-3	12	2	2	16
Gamma-aminobutyric acid receptor subunit beta-2	12	2	2	16
GABA theta subunit	12	2	2	16
Canalicular multispecific organic anion transporter 1	0	17	0	17
Gamma-aminobutyric acid receptor subunit epsilon	12	2	2	16
thyroid hormone receptor beta isoform 2	21	0	0	21
Cytochrome P450 2C9	0	4	0	5
Amine oxidase [flavin-containing] A	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	2
Spike glycoprotein	12	0	1	13
Chain A, HADH2 protein	6	0	0	6
Chain B, HADH2 protein	6	0	0	6
interleukin 8	7	0	0	7
RAR-related orphan receptor gamma	20	0	0	20
Smad3	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	13	0	0	13
estrogen receptor 2 (ER beta)	12	0	0	12
regulator of G-protein signaling 4	6	0	0	6
nonstructural protein 1	7	0	0	7
peroxisome proliferator-activated receptor delta	15	0	0	15
peroxisome proliferator activated receptor gamma	22	0	0	22
Histone H2A.x	7	0	0	7
Caspase-7	4	0	0	4
Bloom syndrome protein isoform 1	9	0	0	9
caspase-3	4	0	0	4
importin subunit beta-1 isoform 1	2	0	0	2
mitogen-activated protein kinase 1	4	0	0	4
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
snurportin-1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
nuclear receptor ROR-gamma isoform 1	11	0	0	11
peripheral myelin protein 22	13	0	0	13
muscleblind-like protein 1 isoform 1	4	0	0	4
neuropeptide S receptor isoform A	4	0	0	4
Beta-glucuronidase	0	2	0	2
Cholinesterase	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	0	0	1
Testosterone 17-beta-dehydrogenase 3	0	2	0	2
Alpha-synuclein	4	3	0	7
Nuclear receptor ROR-gamma	7	0	0	7
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	11	0	0	11
NFKB1 protein, partial	2	0	0	2
GLS protein	9	0	0	9
thyroid stimulating hormone receptor	8	0	0	8
alpha-galactosidase	2	0	0	2
cytochrome P450 2C19 precursor	5	0	0	5
flap endonuclease 1	7	0	0	7
muscarinic acetylcholine receptor M1	4	0	0	4
Cytochrome P450 3A4	0	10	0	13
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Beta-lactamase	9	0	0	9
EWS/FLI fusion protein	9	0	0	9
aryl hydrocarbon receptor	11	0	0	11
tyrosine-protein kinase Yes	2	0	0	2
Estrogen receptor	0	9	4	15
Cellular tumor antigen p53	20	0	0	20
Progesterone receptor	0	1	0	1
Progesterone receptor	0	7	2	9
Glucocorticoid receptor	0	1	0	1
Androgen receptor	0	12	4	18
Androgen receptor	0	1	1	2
Mineralocorticoid receptor	0	1	0	1
Progesterone receptor	0	2	0	2
ALK tyrosine kinase receptor	0	1	0	1
nuclear receptor subfamily 1, group I, member 3	15	0	0	15
thyroid stimulating hormone receptor	11	0	0	11
Genome polyprotein	0	1	1	2
dopamine D1 receptor	3	0	0	3
Fumarate hydratase	3	0	0	3
polyprotein	3	0	0	3
D(1A) dopamine receptor	5	0	0	5
vitamin D3 receptor isoform VDRA	9	0	0	9
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
5-hydroxytryptamine receptor 4	0	6	0	6
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	8	1	10
Beta-1 adrenergic receptor	0	8	2	10
5-hydroxytryptamine receptor 1A	0	2	0	2
Alpha-2A adrenergic receptor	0	7	2	10
D(2) dopamine receptor	0	6	2	8
Alpha-2B adrenergic receptor	0	6	1	8
Alpha-2C adrenergic receptor	0	3	2	6
D	0	1	0	1
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	6	1	8
Alpha-2B adrenergic receptor	0	3	1	4
ATP-dependent translocase ABCB1	0	3	0	3
D(1A) dopamine receptor	0	6	1	7
Alpha-2C adrenergic receptor	0	3	1	4
Alpha-2A adrenergic receptor	0	3	1	4
Alpha-1D adrenergic receptor	0	4	2	7
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	6	2	8
5-hydroxytryptamine receptor 2C	0	6	2	8
5-hydroxytryptamine receptor 1B	0	7	0	7
D(4) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 2B	0	9	2	11
5-hydroxytryptamine receptor 6	0	8	1	9
D(2) dopamine receptor	0	1	1	2
ATPase family AAA domain-containing protein 5	9	0	0	9
Ataxin-2	10	0	0	10
glp-1 receptor, partial	7	0	0	7
vasopressin V1b receptor	1	0	0	1
cAMP-dependent protein kinase type I-alpha regulatory subunit	0	0	1	1
cAMP-dependent protein kinase type II-beta regulatory subunit	0	0	1	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
cAMP-dependent protein kinase catalytic subunit beta isoform 1	0	0	1	1
urokinase plasminogen activator surface receptor precursor	2	0	0	2
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
cAMP-dependent protein kinase catalytic subunit beta isoform 3	0	0	1	1
cytochrome P450 2D6	5	0	0	5
Histamine H3 receptor	0	1	0	1
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Ferritin light chain	6	0	0	6
Vitamin D3 receptor	0	0	1	1
USP1 protein, partial	13	0	0	13
PPM1D protein	3	0	0	3
thioredoxin glutathione reductase	3	0	0	3
Vitamin D-binding protein	0	0	1	1
Cytochrome P450 1A2	0	2	0	3
Cytochrome P450 2D6	0	3	0	3
Vitamin D3 receptor	0	2	3	8
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	3	3
Cytochrome P450 2C19	0	5	0	5
Kappa-type opioid receptor	0	0	1	1
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	1	3
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Lactoperoxidase	0	2	0	2
Carbonic anhydrase 4	0	4	0	6
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase 15	0	3	0	5
Chain A, Cruzipain	5	0	0	5
Luciferase	4	0	0	4
15-lipoxygenase, partial	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
thyroid hormone receptor beta isoform a	7	0	0	7
DNA polymerase kappa isoform 1	3	0	0	3
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
endonuclease IV	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	9	0	0	9
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
heat shock protein beta-1	5	0	0	5
M-phase phosphoprotein 8	6	0	0	6
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	3	0	3
67.9K protein	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	5	0	0	5
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
Adenosine receptor A1	0	3	0	4
Adenosine receptor A2b	0	2	0	2
Adenosine receptor A2a	0	2	0	3
Mu-type opioid receptor	0	5	1	6
ORF73	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
Matrix metalloproteinase-9	0	2	0	2
Inositol monophosphatase 1	2	0	0	2
Isocitrate lyase	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
caspase 7, apoptosis-related cysteine protease	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
caspase-3	3	0	0	3
RAD51	0	1	0	1
huntingtin isoform 2	3	0	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
caspase-1 isoform alpha precursor	1	0	0	1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	1	0	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	2	2	7
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
G-protein coupled bile acid receptor 1	0	0	1	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Gonadotropin-releasing hormone receptor	0	4	1	5
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	4	0	4
Eyes absent homolog 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Amyloid-beta precursor protein	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Histamine H2 receptor	6	0	1	7
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
GALC protein	5	0	0	5
hexokinase-4 isoform 1	3	0	0	3
glucokinase regulatory protein	3	0	0	3
Rap guanine nucleotide exchange factor 3	2	0	0	2
Steryl-sulfatase	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Sodium-dependent serotonin transporter	0	8	0	8
Mu-type opioid receptor	0	0	1	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Mu-type opioid receptor	0	0	1	1
Cytochrome P450 1B1	0	1	0	1
Estrogen receptor beta	0	5	4	10
Ghrelin O-acyltransferase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
acid sphingomyelinase	1	0	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	4	0	4
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	4	0	4
cytochrome P450 2C9 precursor	1	0	0	1
Cocaine esterase	0	1	0	2
Bile salt export pump	0	6	0	6
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
cytochrome P450 2D6 isoform 1	2	0	0	2
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Coagulation factor X	0	1	0	1
Plasminogen	0	2	0	2
Coagulation factor XII	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Serine protease hepsin	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	3	0	3
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	3
Amino acid transporter	0	3	0	3
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Chain A, Probable hydrogenase nickel incorporation protein hypB	0	0	1	1
Chain B, Probable hydrogenase nickel incorporation protein hypB	0	0	1	1
Chain A, ELONGATION FACTOR TU (EF-TU)	0	0	1	1
Chain A, Elongation Factor G	0	0	1	1
Chain A, ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3	0	0	1	1
Chain A, Eukaryotic peptide chain release factor GTP-binding subunit	0	0	1	1
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b	0	0	1	1
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b	0	0	1	1
Chain A, interferon-inducible GTPase	0	0	1	1
Chain A, interferon-inducible GTPase	0	0	1	1
Chain A, Elongation factor 2	0	0	1	1
Chain A, Guanine nucleotide-binding protein G(i), alpha-1 subunit	0	0	1	1
72 kDa type IV collagenase	0	2	0	2
Matrilysin	0	1	0	1
2-dehydropantoate 2-reductase	0	0	2	2
Ras-related protein Rab-7a	0	0	2	2
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	4	0	4
Chain A, Uracil Phosphoribosyltransferase	0	0	1	1
Chain B, Uracil Phosphoribosyltransferase	0	0	1	1
Chain C, Uracil Phosphoribosyltransferase	0	0	1	1
histone deacetylase 9 isoform 3	1	0	0	1
NPYLR7B	0	0	1	1
Beta-1 adrenergic receptor	0	1	2	5
beta-2 adrenergic receptor	2	0	0	2
Beta-2 adrenergic receptor	0	4	3	8
Beta-2 adrenergic receptor	0	4	1	6
Beta-3 adrenergic receptor	0	5	2	7
Beta-1 adrenergic receptor	0	4	2	8
Beta-2 adrenergic receptor	0	0	1	1
D(4) dopamine receptor	0	3	0	3
Alpha-1D adrenergic receptor	0	3	1	4
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	2	1	3
Alpha-1A adrenergic receptor	0	1	3	5
Alpha-1B adrenergic receptor	0	0	2	3
D(1A) dopamine receptor	2	0	0	2
Beta-2 adrenergic receptor	0	2	0	2
Taste receptor type 2 member 38	0	0	2	3
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Glutamate receptor ionotropic, NMDA 2A	0	0	1	3
Glutamate receptor ionotropic, NMDA 2B	0	0	1	3
Glutamate receptor ionotropic, NMDA 2C	0	0	1	3
Beta-2 adrenergic receptor	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	0	1	3
Taste receptor type 2 member 42	0	0	1	1
Beta-2 adrenergic receptor	0	1	3	5
Glutamate receptor ionotropic, NMDA 3B	0	0	1	3
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
Glutamate receptor ionotropic, NMDA 3A	0	0	1	3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chymotrypsinogen A	0	2	0	2
Estrogen receptor beta	0	1	0	2
Solute carrier family 22 member 1	0	2	0	2
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Camphor 5-monooxygenase	0	0	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Epoxide hydrolase 1	0	0	0	1
Aldo-keto reductase family 1 member B1	0	4	0	4
Muscarinic acetylcholine receptor M2	0	5	1	6
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Cytochrome P450 2C8	0	3	0	3
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Translocator protein	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Estrogen receptor	0	1	0	2
Substance-K receptor	0	4	0	4
UDP-glucuronosyltransferase 1A1	0	2	0	2
Sodium-dependent noradrenaline transporter	0	5	0	5
Histamine H2 receptor	0	6	0	6
Type-1 angiotensin II receptor	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Delta-type opioid receptor	0	5	1	6
Cytochrome P450 4F2	0	1	0	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Sodium/bile acid cotransporter	0	2	0	2
Lanosterol 14-alpha demethylase	0	3	1	4
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Gonadotropin-releasing hormone receptor	0	1	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
Polyphenol oxidase 2	0	3	0	6
Carbonic anhydrase 12	0	2	0	4
Epidermal growth factor receptor	0	2	0	2
Plasma kallikrein	0	0	0	2
Tyrosine-protein kinase Lck	0	2	0	2
Tyrosine-protein kinase Fyn	0	2	0	2
Carbonic anhydrase 3	0	1	0	3
Tyrosinase	0	1	0	1
Carbonic anhydrase 6	0	1	0	3
Carbonic anhydrase 5A, mitochondrial	0	2	0	4
Carbonic anhydrase 7	0	1	0	3
Solute carrier family 15 member 1	0	1	0	1
Carbonic anhydrase	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	2	0	2
SLC16A10 protein	0	0	0	2
Carbonic anhydrase 9	0	3	0	5
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Carbonic anhydrase 13	0	1	0	3
Carbonic anhydrase 14	0	2	0	4
Carbonic anhydrase 5B, mitochondrial	0	1	0	3
phosphoglycerate kinase	1	0	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
HLA class I histocompatibility antigen, A alpha chain	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
PINK1	2	0	0	2
Parkin	2	0	0	2
Mineralocorticoid receptor	0	3	0	4
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Dopamine beta-hydroxylase	0	2	0	2
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	2	0	0	2
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Glutamate 5-kinase	0	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Albumin	0	1	2	3
Muscarinic acetylcholine receptor M1	0	3	1	4
Muscarinic acetylcholine receptor M3	0	3	1	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Endothelin-1 receptor	0	1	1	2
5-hydroxytryptamine receptor 1B	0	2	1	3
Adenosine receptor A2a	0	3	1	4
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Vasopressin V1a receptor	0	1	1	2
Kappa-type opioid receptor	0	3	1	4
5-hydroxytryptamine receptor 7	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	0	4
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
NADH-cytochrome b5 reductase 3	0	1	0	1
Myeloperoxidase	0	2	0	2
Thyroid peroxidase	0	1	0	1
Butyrophilin subfamily 3 member A1	0	0	2	3
4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
H	0	2	0	2
Phosphotransferase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Retina-specific copper amine oxidase	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	3
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	0	1	0	1
Renin	0	1	0	1
Tumor necrosis factor	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	4
Prostaglandin G/H synthase 1	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	1	4
Sodium-dependent serotonin transporter	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	1	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	1	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	3
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	3
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Phosphodiesterase	0	1	0	1
Phosphodiesterase	0	1	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Solute carrier family 22 member 6	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Cystathionine gamma-lyase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	2
Solute carrier family 22 member 7	0	0	0	2
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
glucocerebrosidase	2	0	0	2
thyrotropin-releasing hormone receptor	1	0	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
interferon gamma precursor	0	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
ras-related protein Rab-9A	1	0	0	1
streptokinase A precursor	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Serine/threonine-protein kinase D3	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Integrin beta-3	1	0	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	2	0	2
Estrogen receptor	0	0	1	2
Procathepsin L	0	0	1	1
Muscarinic acetylcholine receptor M4	0	2	0	2
Integrin alpha-IIb	1	0	0	1
Muscarinic acetylcholine receptor M5	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Protein kinase C alpha type	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
Protein kinase C eta type	0	1	0	1
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Adenosine receptor A1	0	4	0	4
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	2	0	2
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
serine/threonine-protein kinase PLK1	2	0	0	2
Solute carrier organic anion transporter family member 1A4	0	1	0	3
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	3
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Prothrombin	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Phospholipase A-2-activating protein	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
Thymidine kinase, cytosolic	0	2	0	3
DNA polymerase beta	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
Thymidine kinase, cytosolic	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Protease	0	1	1	2
Solute carrier family 22 member 11	0	0	0	1
Thymidine kinase	0	1	0	2
Solute carrier family 22 member 7	0	0	0	1
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(10)

Research Excerpts

Overview

Treatment

Research

Studies (304)

Protein Targets (788)

Albright Syndrome

Synonyms(10)

Research Excerpts

Overview

Treatment

Research

Studies (304)

Drugs Studied (130)

Protein Targets (788)