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triiodothyronine and Albright Syndrome

triiodothyronine has been researched along with Albright Syndrome in 6 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
" Thyroid crisis is even rare in patients with MAS, and we report the clinical outcomes of the first case of a MAS patient with atypical triiodothyronine (T3) hyperthyroidism who developed thyroid crisis after orthopedic surgery."8.12Postoperative thyroid crisis in an 11-year old male with McCune-Albright syndrome and atypical triiodothyronine hyperthyroidism: A case report. ( Hu, C; Hu, J, 2022)
"A 17-year-old girl with McCune-Albright syndrome (MAS) was suspected of having central hypothyroidism based on an inappropriately normal thyroid-stimulating hormone (TSH) and low free thyroxine (fT4)."7.81Low serum free thyroxine level in a girl with McCune-Albright syndrome. ( Pajuväli, A; Peet, A; Roosimaa, M; Tillmann, V, 2015)
"McCune-Albright syndrome (MAS) is caused by mutations in GNAS (most often R201C or R201H) leading to constitutive cAMP signaling and multiple endocrine dysfunctions, including morphological and functional thyroid involvement."5.35The role of type 1 and type 2 5'-deiodinase in the pathophysiology of the 3,5,3'-triiodothyronine toxicosis of McCune-Albright syndrome. ( Brillante, BA; Celi, FS; Cherman, N; Chidakel, A; Collins, MT; Coppotelli, G; Feuillan, PP; Kelly, M; Shawker, T, 2008)
" Thyroid crisis is even rare in patients with MAS, and we report the clinical outcomes of the first case of a MAS patient with atypical triiodothyronine (T3) hyperthyroidism who developed thyroid crisis after orthopedic surgery."4.12Postoperative thyroid crisis in an 11-year old male with McCune-Albright syndrome and atypical triiodothyronine hyperthyroidism: A case report. ( Hu, C; Hu, J, 2022)
"A 17-year-old girl with McCune-Albright syndrome (MAS) was suspected of having central hypothyroidism based on an inappropriately normal thyroid-stimulating hormone (TSH) and low free thyroxine (fT4)."3.81Low serum free thyroxine level in a girl with McCune-Albright syndrome. ( Pajuväli, A; Peet, A; Roosimaa, M; Tillmann, V, 2015)
"To identify the molecular defect by which psychomotor retardation is caused in two brothers with congenital hypothyroidism who received adequate treatment with l-thyroxine."3.72A new heterozygous mutation (L338N) in the human Gsalpha (GNAS1) gene as a cause for congenital hypothyroidism in Albright's hereditary osteodystrophy. ( Ahrens, W; Hiort, O; Pohlenz, J, 2003)
"McCune-Albright syndrome (MAS) is caused by mutations in GNAS (most often R201C or R201H) leading to constitutive cAMP signaling and multiple endocrine dysfunctions, including morphological and functional thyroid involvement."1.35The role of type 1 and type 2 5'-deiodinase in the pathophysiology of the 3,5,3'-triiodothyronine toxicosis of McCune-Albright syndrome. ( Brillante, BA; Celi, FS; Cherman, N; Chidakel, A; Collins, MT; Coppotelli, G; Feuillan, PP; Kelly, M; Shawker, T, 2008)
"We report a girl with McCune-Albright syndrome who presented with Cushing syndrome from adrenal hypersecretion and gonadotrophin-independent precocious puberty in the first year of life."1.30Occult T3 toxicosis in McCune-Albright syndrome. ( Brogan, P; Khadilkar, VV; Stanhope, R, 1998)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Hu, J1
Hu, C1
Roosimaa, M1
Pajuväli, A1
Peet, A1
Tillmann, V1
Pohlenz, J1
Ahrens, W1
Hiort, O1
Celi, FS1
Coppotelli, G1
Chidakel, A1
Kelly, M1
Brillante, BA1
Shawker, T2
Cherman, N1
Feuillan, PP2
Collins, MT1
Brogan, P1
Khadilkar, VV1
Stanhope, R1
Rose, SR1
Jones, J1
Jeevanram, RK1
Nisula, BC1

Other Studies

6 other studies available for triiodothyronine and Albright Syndrome

ArticleYear
Postoperative thyroid crisis in an 11-year old male with McCune-Albright syndrome and atypical triiodothyronine hyperthyroidism: A case report.
    Medicine, 2022, Mar-04, Volume: 101, Issue:9

    Topics: Child; Femur; Fibrous Dysplasia, Polyostotic; Humans; Hyperthyroidism; Male; Postoperative Complicat

2022
Low serum free thyroxine level in a girl with McCune-Albright syndrome.
    BMJ case reports, 2015, Jan-05, Volume: 2015

    Topics: Adolescent; Female; Fibrous Dysplasia, Polyostotic; Humans; Hyperthyroidism; Hypothyroidism; Thyroxi

2015
A new heterozygous mutation (L338N) in the human Gsalpha (GNAS1) gene as a cause for congenital hypothyroidism in Albright's hereditary osteodystrophy.
    European journal of endocrinology, 2003, Volume: 148, Issue:4

    Topics: Calcium; Child; Erythrocyte Membrane; Fibrous Dysplasia, Polyostotic; Genotype; GTP-Binding Protein

2003
The role of type 1 and type 2 5'-deiodinase in the pathophysiology of the 3,5,3'-triiodothyronine toxicosis of McCune-Albright syndrome.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Cells, Cultured; Child; Child, Preschool; Ch

2008
Occult T3 toxicosis in McCune-Albright syndrome.
    Hormone research, 1998, Volume: 50, Issue:2

    Topics: Antithyroid Agents; Carbimazole; Child, Preschool; Female; Fibrous Dysplasia, Polyostotic; Humans; T

1998
Thyroid abnormalities in the McCune-Albright syndrome: ultrasonography and hormonal studies.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Female; Fibrous Dysplasia, Polyostotic; Humans; Thyroid Disease

1990