Compounds > benethamine penicillin
Page last updated: 2024-12-06

benethamine penicillin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID65054
CHEMBL ID2107679
MeSH IDM0115442

Synonyms (25)

Synonym
penicillinbenethaminum
benethamine penicillin
benetolin
benetacil
einecs 212-029-8
benzylpenicillin salt of n-benzylphenethylamine
benethamine penicilline [inn-french]
benethaminum penicillinum [inn-latin]
benethamine-penicillin
penicilina-benetamina [inn-spanish]
benethamine penicillin [inn:ban]
benapen
betapen
penicillin g benethamine
751-84-8
CHEMBL2107679
o3s7rwt8r5 ,
unii-o3s7rwt8r5
benethamine penicillin [inn]
penicillin g benethamine [mi]
benethamine penicillin [mart.]
benethamine penicillin [who-dd]
DTXSID10226072
penicillin benethamine
Q27123272

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"In a comparative kinetic study of the serum concentrations of two penicillin complexes--medium-long-acting (benethamine penicillin) and long-acting (benzathine bipenicillin)--after a single injection in young adults and elderly people, the following results were confirmed statistically: (a) age was a major factor in the variations in serum penicillin concentrations and in their persistence in the serum; (b) the penicillin was absorbed faster in young than in elderly subjects even when a long-acting complex was used; (c) serum concentrations below the level regarded as lethal for treponemes appeared much earlier and more frequently in young than in old people; and (d) the bioequivalence between penicillin preparations could not be estimated solely for the number of units of the agent used but from the bioavailability of the chosen formulation."( Kinetic study of serum penicillin concentrations after single doses of benzathine and benethamine penicillins in young and old people.
Collart, P; Durel, J; Herlin, A; Milovanovic, A; Poitevin, M, 1980)		0.7

Dosage Studied

ExcerptRelevanceReference
" Thus a uniform and standard penicillin dosage allowing no safety margin may help in the superficial healing of a syphilitic chancre or the resolution of a roseola but it will certainly be insufficient to kill Treponema pallidum."( Kinetic study of serum penicillin concentrations after single doses of benzathine and benethamine penicillins in young and old people.
Collart, P; Durel, J; Herlin, A; Milovanovic, A; Poitevin, M, 1980)		0.48
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
benethamine salt
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-199011 (84.62)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.19

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.19 (24.57)
Research Supply Index2.83 (2.92)
Research Growth Index4.16 (4.65)
Search Engine Demand Index29.80 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.19)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (6.67%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (93.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
penicillin g
Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.. benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.		5.28131penicillin allergen;
penicillin		antibacterial drug;
drug allergen;
epitope
cloxacillin
Cloxacillin: A semi-synthetic antibiotic that is a chlorinated derivative of OXACILLIN.. cloxacillin : A semisynthetic penicillin antibiotic carrying a 3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamido group at position 6.		1.9610penicillin allergen;
penicillin;
semisynthetic derivative		antibacterial agent;
antibacterial drug
framycetin
Framycetin: A component of NEOMYCIN that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed). framycetin : A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B.		8.4311aminoglycosideallergen;
antibacterial drug;
Escherichia coli metabolite
dihydrostreptomycin sulfate
Dihydrostreptomycin Sulfate: A semi-synthetic aminoglycoside antibiotic that is used in the treatment of TUBERCULOSIS.		1.9610
benzathine cloxacillin
benzathine cloxacillin: Orbenin D.C. contains 500 mg of benzathine cloxacillin		1.9610benzathine(2+) salt
penethamate hydroiodide
penethamate hydroiodide: structure		3.4311
ConditionIndicatedRelationship StrengthStudiesTrials
Ovine Diseases
[description not available]		03.4311
Infections, Staphylococcal
[description not available]		03.4311
Group A Strep Infection
[description not available]		03.4311
Mastitis
INFLAMMATION of the BREAST, or MAMMARY GLAND.		03.4311
Staphylococcal Infections
Infections with bacteria of the genus STAPHYLOCOCCUS.		03.4311
Streptococcal Infections
Infections with bacteria of the genus STREPTOCOCCUS.		03.4311
Disease
A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.		01.9310
Great Pox
[description not available]		02.6430
Syphilis
A contagious venereal disease caused by the spirochete TREPONEMA PALLIDUM.		07.6430
Bacillus anthracis Infection
[description not available]		01.9610
Bovine Diseases
[description not available]		02.3720
Anthrax
An acute infection caused by the spore-forming bacteria BACILLUS ANTHRACIS. It commonly affects hoofed animals such as sheep and goats. Infection in humans often involves the skin (cutaneous anthrax), the lungs (inhalation anthrax), or the gastrointestinal tract. Anthrax is not contagious and can be treated with antibiotics.		01.9610
Congenital Syphilis
[description not available]		01.9610
Syphilis, Congenital
Syphilis acquired in utero and manifested by any of several characteristic tooth (Hutchinson's teeth) or bone malformations and by active mucocutaneous syphilis at birth or shortly thereafter. Ocular and neurologic changes may also occur.		01.9610
HIV Coinfection
[description not available]		01.9710
Skin Syphilis
[description not available]		01.9710
HIV Infections
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).		01.9710
Infectious Keratoconjunctivitis
[description not available]		01.9710
Experimental Lung Inflammation
Inflammation of any part, segment or lobe, of the lung parenchyma.		01.9710
Pneumonia
Infection of the lung often accompanied by inflammation.		06.9710