Proteins > Corticosteroid 11-beta-dehydrogenase isozyme 2
Page last updated: 2024-08-07 23:33:56
Corticosteroid 11-beta-dehydrogenase isozyme 2
An 11-beta-hydroxysteroid dehydrogenase type 2 that is encoded in the genome of rat. [OMA:P50233, PRO:DNx]
Synonyms
EC 1.1.1.-;
11-beta-hydroxysteroid dehydrogenase type 2;
11-DH2;
11-beta-HSD2;
NAD-dependent 11-beta-hydroxysteroid dehydrogenase
Research
Bioassay Publications (2)
Timeframe | Studies on this Protein(%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
glycyrrhetinic acid | Rattus norvegicus (Norway rat) | IC50 | 0.3600 | 2 | 2 |
Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors.Bioorganic & medicinal chemistry, , Mar-15, Volume: 19, Issue:6, 2011
Synthesis of glycyrrhetinic acid derivatives for the treatment of metabolic diseases.Bioorganic & medicinal chemistry, , Jan-01, Volume: 18, Issue:1, 2010