Page last updated: 2024-12-08
albicanol
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
albicanol: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 171360 |
| CHEBI ID | 155904 |
| SCHEMBL ID | 7760094 |
| MeSH ID | M0404443 |
Synonyms (16)
| Synonym |
|---|
| albicanol |
| [(1s,4as,8as)-5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl]methanol |
| (1s,4aalpha)-decahydro-5,5,8abeta-trimethyl-2-methylenenaphthalene-1-methanol |
| CHEBI:155904 |
| (4aalpha)-2-methylene-5,5,8abeta-trimethyldecalin-1beta-methanol |
| (4aalpha)-decahydro-5,5,8abeta-trimethyl-2-methylenenaphthalene-1beta-methanol |
| (8as)-albicanol |
| 54632-04-1 |
| [(1s,4as,8as)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1h-naphthalen-1-yl]methanol |
| ccris 8459 |
| SCHEMBL7760094 |
| DTXSID80969909 |
| (5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl)methanol |
| HY-119635 |
| CS-0077180 |
| AKOS040750293 |
Research Excerpts
Overview
Albicanol is a sesquiterpenoid extracted from the medicinal plant Dryopteris fragrans. Albicanol has been shown to exhibit anti-aging and antioxidant activity.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Albicanol is a sesquiterpenoid extracted from the medicinal plant Dryopteris fragrans that has previously been shown to exhibit anti-aging and antioxidant activity." | ( Albicanol antagonizes Cd-induced apoptosis through a NO/iNOS-regulated mitochondrial pathway in chicken liver cells. Chang, Y; Cui, Y; Guan, Y; Song, N; Zhao, X, 2021) | 2.79 |
| "Albicanol is a natural terpenoid derived from Dryopteris fragrans. " | ( Albicanol Alleviates D-Galactose-Induced Aging and Improves Behavioral Ability Via by Alleviating Oxidative Stress-Induced Damage. Chang, Y; Chen, LL; Guan, Y; Li, J; Song, CH; Tang, X; Wang, HM; Wang, WF; Zhang, DR, 2021) | 3.51 |
Treatment
| Excerpt | Reference | Relevance |
|---|---|---|
| "Albicanol treatment also inhibited the secretion of inflammatory TNF-a and IL-1b." | ( Albicanol Alleviates D-Galactose-Induced Aging and Improves Behavioral Ability Via by Alleviating Oxidative Stress-Induced Damage. Chang, Y; Chen, LL; Guan, Y; Li, J; Song, CH; Tang, X; Wang, HM; Wang, WF; Zhang, DR, 2021) | 2.79 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Roles (7)
| Role | Description |
|---|---|
| antifungal agent | An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. |
| plant metabolite | Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. |
| antineoplastic agent | A substance that inhibits or prevents the proliferation of neoplasms. |
| fungal metabolite | Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. |
| mammalian metabolite | Any animal metabolite produced during a metabolic reaction in mammals. |
| antifeedant | A substance that prevents pests from feeding. |
| marine metabolite | Any metabolite produced during a metabolic reaction in marine macro- and microorganisms. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Drug Classes (4)
| Class | Description |
|---|---|
| sesquiterpenoid | Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). |
| primary alcohol | A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. |
| homoallylic alcohol | An aliphatic alcohol where the hydroxy carbon is beta to a double bond. |
| carbobicyclic compound | A bicyclic compound in which all the ring atoms are carbon. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Research
Studies (12)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 6 (50.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.85
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.85) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||