N(alpha)-benzoylarginineamide: RN given refers to parent cpd(S)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 188293 |
| CHEMBL ID | 2323121 |
| SCHEMBL ID | 158990 |
| MeSH ID | M0114682 |
| Synonym |
|---|
| 965-03-7 |
| BAG , |
| n(alpha)-benzoylarginineamide |
| n-[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]benzamide |
| n-benzoyl-l-argininamide |
| benzamide, n-(1-(aminocarbonyl)-4-((aminoiminomethyl)amino)butyl)-, (s)- |
| nalpha-benzoylarginineamide |
| n-baa |
| bz-arg-nh2 |
| CHEMBL2323121 |
| n-(1-carbamoyl-4-guanidino-butyl)benzamide hydrate hydrochloride |
| SCHEMBL158990 |
| n-.alpha.-benzoyl-l-argininamide hydrochloride |
| UMKJQJGLFKDADN-JTQLQIEISA-N |
| n(.alpha.)-benzoyl-l-arginine amide |
| n-(1-(aminocarbonyl)-4-([amino(imino)methyl]amino)butyl)benzamide, (s)- |
| AKOS025289416 |
| benzoylargininamid |
| n-(5-carbamimidamido-1-hydroxy-1-iminopentan-2-yl)benzenecarboximidic acid |
| DTXSID70914488 |
| PD165953 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| chromatin organization | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| nucleosome assembly | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| chromatin remodeling | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| stem cell population maintenance | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| protein modification process | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| post-translational protein modification | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| innate immune response | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| protein-arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| calcium ion binding | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| protein binding | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| identical protein binding | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone H3R2 arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone H3R8 arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone H3R17 arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone H3R26 arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| nucleus | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| nucleoplasm | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| cytosol | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| protein-containing complex | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| nucleus | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| cytoplasm | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1338999 | Inhibition of West Nile virus His-tagged NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) at 50 uM using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate preincubated for 15 mins followed by substrate addition measured for 15 mins by fluoresce | 2017 | Journal of medicinal chemistry, 01-12, Volume: 60, Issue:1 | Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology. |
| AID1338997 | Inhibition of Dengue virus serotype 2 His-tagged NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) at 50 uM using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate preincubated for 15 mins followed by substrate addition measured for 15 mins by fluor | 2017 | Journal of medicinal chemistry, 01-12, Volume: 60, Issue:1 | Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology. |
| AID725598 | Activity of human PAD4 | 2013 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3 | Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||