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ChEBI ID: 24793
| Member | Definition | Role |
|---|---|---|
| 1-acetylisatin | An indoledione consisting of isatin carrying an N-acetyl substituent. | N-acetylisatin |
| aminochrome 1 | A member of the class of indoledione that is 2,3,5,6-tetrahydro-1H-indole carrying oxo groups at positions 5 and 6; major microspecies at pH 7.3. It is an endogenous compound formed during dopamine oxidation and can induce neurotoxicity under certain aberrant conditions and induce Parkinson-like syndrome. | dopaminechrome (keto form) |
| isatin | An indoledione that is the 2,3-diketo derivative of indole. | isatin |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 149 (13.38) | 18.7374 |
| 1990's | 104 (9.34) | 18.2507 |
| 2000's | 209 (18.76) | 29.6817 |
| 2010's | 468 (42.01) | 24.3611 |
| 2020's | 184 (16.52) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 3 (0.25%) | 5.53% |
| Reviews | 57 (4.84%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,118 (94.91%) | 84.16% |