Page last updated: 2024-09-27

Asperger Syndrome

A disorder beginning in childhood whose essential features are persistent impairment in reciprocal social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities. These symptoms may limit or impair everyday functioning. (From DSM-5)

Synonyms(1)

Synonym
Asperger Syndrome

Research Excerpts

Overview

ExcerptReference
"The etiology of Asperger syndrome is essentially unknown, but abnormality of the dopamine system has been shown in clinically overlapping disorders."( Aalto, S; Autti, TH; Bergman, J; Eskola, O; Hietala, JA; Kulomäki, TA; Metsähonkala, L; Nieminen-von Wendt, TS; Vanhala, R; von Wendt, LO, 2004)
"Asperger syndrome is associated with various dysfunctional and problematic behaviors, in addition to the core features of communication and social skills dysfunction that define these conditions."( Yamada, S, 2007)

Research

Studies (138)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's1 (0.72)12.5806
2000's73 (52.90)18.1394
2010's61 (44.20)28.8240
2020's3 (2.17)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
choline0low80
creatine0low70
cytosine0low10
glycine0low10
dihydroxyphenylalanine0low10
inositol0low50
melatonin0medium31
1-(3-chlorophenyl)piperazine0medium11
3,4-methylenedioxyamphetamine0low40
bumetanide0medium31
buspirone0medium11
carbamazepine0low10
citalopram0medium42
clomipramine0low10
clonidine0low10
valproic acid0medium41
flecainide0low10
fluoxetine0medium21
guanfacine0low10
memantine0low10
methylphenidate0medium72
propranolol0medium11
trazodone0low10
trientine0low10
alanine0low20
aspartic acid0low90
glutamine0low30
lysine0low10
carbostyril0medium42
tyrosine0low10
phenylalanine0low10
asparagine0low10
valine0low10
isoleucine0low10
ethylmercuric chloride0low10
cyclohexanol0low10
isoxazoles0low10
fluorobenzenes0low10
lithium carbonate0low20
s,n,n'-tripropylthiocarbamate0low30
glutamic acid0low40
paroxetine0low20
atomoxetine hydrochloride0low10
venlafaxine hydrochloride0low10
n-acetylaspartic acid0low90
milnacipran0low10
fluorodeoxyglucose f180low20
sertraline0medium31
nicotine0low10
homocysteine0low10
oxytocin0medium54
tretinoin0low10
lithium0low10
bilirubin0low10
mdl 1009070low10
fluvoxamine0medium31
phosphocreatine0low30
paliperidone palmitate0low10
technetium tc 99m exametazime0low10
phosphatidylcholines0low10
thimerosal0low30
n,n-dimethyl-2-(2-amino-4-cyanophenylthio)benzylamine0low10
piperidines0low20
guanosine0low10
olanzapine0medium42
eye0low50
ego0low40

Protein Targets (798)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE110011
5-hydroxytryptamine receptor 3E0404
acetylcholinesterase8008
TDP1 protein220022
cytochrome P450 2D6140014
v-jun sarcoma virus 17 oncogene homolog (avian)9009
cytochrome P450 2D6 isoform 18008
cellular tumor antigen p53 isoform a3003
cytochrome P450 2C19 precursor5005
cytochrome P450 2C9 precursor4004
thyroid hormone receptor beta isoform a8008
thyroid hormone receptor beta isoform 2150015
huntingtin isoform 24004
peripheral myelin protein 22110011
cytochrome P450 3A4 isoform 17007
muscarinic acetylcholine receptor M1100010
Gamma-aminobutyric acid receptor subunit pi73111
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
ATP-binding cassette sub-family C member 3016016
Multidrug resistance-associated protein 4016016
5-hydroxytryptamine receptor 3B0404
Bile salt export pump021021
Beta-1 adrenergic receptor0314
5-hydroxytryptamine receptor 1A010919
5-hydroxytryptamine receptor 2C013114
D(2) dopamine receptor014216
5-hydroxytryptamine receptor 2A015116
Gamma-aminobutyric acid receptor subunit beta-173111
Alpha-1B adrenergic receptor015217
Gamma-aminobutyric acid receptor subunit delta73111
Gamma-aminobutyric acid receptor subunit gamma-273212
D0808
5-hydroxytryptamine receptor 1A017220
Gamma-aminobutyric acid receptor subunit alpha-573111
Gamma-aminobutyric acid receptor subunit alpha-373111
Gamma-aminobutyric acid receptor subunit gamma-173111
Gamma-aminobutyric acid receptor subunit alpha-273111
Alpha-1D adrenergic receptor014216
5-hydroxytryptamine receptor 2A023326
5-hydroxytryptamine receptor 2C023225
Gamma-aminobutyric acid receptor subunit alpha-473111
Gamma-aminobutyric acid receptor subunit gamma-373111
5-hydroxytryptamine receptor 1B013114
5-hydroxytryptamine receptor 1D0415
Gamma-aminobutyric acid receptor subunit alpha-673111
5-hydroxytryptamine receptor 1F0415
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 2B012113
Sodium-dependent serotonin transporter028634
5-hydroxytryptamine receptor 7 0415
5-hydroxytryptamine receptor 70617
Alpha-1B adrenergic receptor0528
Glutamate receptor ionotropic, NMDA 1 09214
5-hydroxytryptamine receptor 2B023225
Alpha-1A adrenergic receptor017320
5-hydroxytryptamine receptor 3A0505
Histamine H2 receptor6107
5-hydroxytryptamine receptor 6012113
Beta-2 adrenergic receptor0202
D(2) dopamine receptor013013
Gamma-aminobutyric acid receptor subunit alpha-173212
Gamma-aminobutyric acid receptor subunit beta-373111
Gamma-aminobutyric acid receptor subunit beta-273212
Glutamate receptor ionotropic, NMDA 2A 08213
Glutamate receptor ionotropic, NMDA 2B08213
Glutamate receptor ionotropic, NMDA 2C08213
Glutamate receptor ionotropic, NMDA 2D08213
5-hydroxytryptamine receptor 3D0404
Glutamate receptor ionotropic, NMDA 3B08213
5-hydroxytryptamine receptor 3C0404
GABA theta subunit73111
Canalicular multispecific organic anion transporter 1014014
Gamma-aminobutyric acid receptor subunit epsilon73111
Glutamate receptor ionotropic, NMDA 3A08213
Sodium-dependent noradrenaline transporter 020323
Sodium-dependent dopamine transporter0819
5-hydroxytryptamine receptor 60112
Sodium-dependent serotonin transporter08210
5-hydroxytryptamine receptor 5A0112
5-hydroxytryptamine receptor 5B0112
5-hydroxytryptamine receptor 3A0213
Sodium-dependent dopamine transporter 016319
5-hydroxytryptamine receptor 4 0112
5-hydroxytryptamine receptor 3B0213
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE7007
Carbonic anhydrase 103012
Carbonic anhydrase 203012
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0002
Proton-coupled amino acid transporter 10505
Adenosine deaminase0001
Carbonic anhydrase 40002
Chain A, JmjC domain-containing histone demethylation protein 3A3003
hypoxia-inducible factor 1 alpha subunit6006
RAR-related orphan receptor gamma110011
SMAD family member 22002
Fumarate hydratase5005
USP1 protein, partial8008
PPM1D protein3003
SMAD family member 32002
GLI family zinc finger 3200020
Microtubule-associated protein tau7007
AR protein190019
estrogen receptor 2 (ER beta)9009
nuclear receptor subfamily 1, group I, member 3130013
progesterone receptor8008
EWS/FLI fusion protein6006
glucocorticoid receptor [Homo sapiens]110011
retinoic acid nuclear receptor alpha variant 1160016
retinoid X nuclear receptor alpha8008
estrogen-related nuclear receptor alpha140014
farnesoid X nuclear receptor6006
pregnane X nuclear receptor100010
estrogen nuclear receptor alpha190019
G7007
polyprotein5005
67.9K protein4004
peroxisome proliferator-activated receptor delta7007
peroxisome proliferator activated receptor gamma9009
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
euchromatic histone-lysine N-methyltransferase 2220022
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
thyroid stimulating hormone receptor9009
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a7007
lysosomal alpha-glucosidase preproprotein3003
mu-type opioid receptor isoform MOR-10011
nuclear factor erythroid 2-related factor 2 isoform 28008
potassium voltage-gated channel subfamily H member 2 isoform d9009
transcriptional regulator ERG isoform 34004
heat shock protein beta-13003
nuclear factor erythroid 2-related factor 2 isoform 1140014
nuclear receptor ROR-gamma isoform 15005
geminin190019
histone acetyltransferase KAT2A isoform 17007
5-hydroxytryptamine receptor 2A0011
neuropeptide S receptor isoform A3003
Solute carrier family 22 member 20305
5-hydroxytryptamine receptor 3A0112
Voltage-dependent calcium channel gamma-2 subunit8008
Interferon beta9009
HLA class I histocompatibility antigen, B alpha chain 7007
Cellular tumor antigen p53120012
ATP-dependent translocase ABCB10608
Cytochrome P450 3A40718
Neuronal acetylcholine receptor subunit alpha-41327
Neuronal acetylcholine receptor subunit beta-21327
Alpha-2C adrenergic receptor016320
Glutamate receptor 292112
Muscarinic acetylcholine receptor M3012113
D(1A) dopamine receptor0819
D(4) dopamine receptor0404
D(1B) dopamine receptor0101
Alpha-1D adrenergic receptor015218
D(4) dopamine receptor0606
Histamine H1 receptor0303
Alpha-1A adrenergic receptor07311
Histamine H1 receptor013114
D(3) dopamine receptor011112
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0303
Spike glycoprotein100111
Inositol monophosphatase 17007
Potassium voltage-gated channel subfamily H member 2022022
Multidrug and toxin extrusion protein 20303
Inositol hexakisphosphate kinase 17007
Multidrug and toxin extrusion protein 10404
Histamine H3 receptor0404
cytochrome P450 2C9, partial7007
Neutral amino acid transporter A0202
Neutral amino acid transporter B(0)0202
Carbonic anhydrase-like protein, putative0007
Amino acid transporter0202
Chain A, Ferritin light chain5005
phosphopantetheinyl transferase8008
aldehyde dehydrogenase 1 family, member A1120012
arylsulfatase A120012
Bloom syndrome protein isoform 18008
lethal factor (plasmid)3003
lamin isoform A-delta10170017
Metabotropic glutamate receptor 60124
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
glp-1 receptor, partial4004
cytochrome P450 family 3 subfamily A polypeptide 4110011
IDH16006
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
Chain A, 2-oxoglutarate Oxygenase7007
Chain A, Cruzipain4004
vitamin D3 receptor isoform VDRA5005
DNA polymerase kappa isoform 15005
caspase-1 isoform alpha precursor1001
Caspase-72002
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10203
Luciferase5005
thioredoxin reductase180018
ATAD5 protein, partial7007
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
thyroid stimulating hormone receptor7007
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
chromobox protein homolog 1110011
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
muscleblind-like protein 1 isoform 11001
Solute carrier family 22 member 60101
Carbonic anhydrase 120307
Carbonic anhydrase 30306
Carbonic anhydrase 40307
Carbonic anhydrase 60307
Carbonic anhydrase 5A, mitochondrial0307
Carbonic anhydrase 70307
Solute carrier family 12 member 20101
Disintegrin and metalloproteinase domain-containing protein 172002
Carbonic anhydrase 90307
Carbonic anhydrase 130205
Carbonic anhydrase 140307
Carbonic anhydrase 5B, mitochondrial0307
ATP-dependent phosphofructokinase140014
regulator of G-protein signaling 4110011
D(1A) dopamine receptor130013
Bile salt export pump0404
Beta-2 adrenergic receptor0304
Angiotensin-converting enzyme 0101
Beta-1 adrenergic receptor0416
D(3) dopamine receptor0707
Alpha-2B adrenergic receptor0819
D(2) dopamine receptor0101
Alpha-2C adrenergic receptor0819
Alpha-2A adrenergic receptor0819
D(1B) dopamine receptor0404
Beta-3 adrenergic receptor0303
Alpha-2A adrenergic receptor0202
D0101
5-hydroxytryptamine receptor 2A0101
D0101
Sigma non-opioid intracellular receptor 1017017
Lysosomal alpha-glucosidase0101
Chain A, Beta-lactamase3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
mitogen-activated protein kinase 17007
Vpr1001
Albumin0044
Major prion protein0011
Sodium channel protein type 1 subunit alpha0303
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0202
Cytochrome P450 2C9 0617
UDP-glucuronosyltransferase 2B70103
Cytochrome P450 2B60011
Sodium channel protein type 4 subunit alpha0102
Cytochrome P450 2J20505
Sodium channel protein type 9 subunit alpha0202
Frizzled-80011
P2X purinoceptor 40202
Chain A, serum paraoxonase0101
Neutrophil cytosol factor 10101
Carbonic anhydrase 130102
Poly [ADP-ribose] polymerase tankyrase-20101
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 1 0609
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30427
Neuronal acetylcholine receptor subunit alpha-20326
Neuronal acetylcholine receptor subunit beta-30326
Neuronal acetylcholine receptor subunit beta-40427
Neuronal acetylcholine receptor subunit alpha-50326
Acetylcholinesterase0505
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60427
Neuronal acetylcholine receptor subunit alpha-90326
Neuronal acetylcholine receptor subunit alpha-70326
Solute carrier family 22 member 10304
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100326
Solute carrier family 22 member 20203
NPC intracellular cholesterol transporter 1 precursor4004
survival motor neuron protein isoform d5005
Sodium-dependent noradrenaline transporter0303
5-hydroxytryptamine receptor 4018018
Aldo-keto reductase family 1 member B1011011
Tryptophan 5-hydroxylase 10202
Angiotensin-converting enzyme011011
Aldo-keto reductase family 1 member B10202
Aromatase0101
5-hydroxytryptamine receptor 70505
Sigma intracellular receptor 20404
Sodium-dependent serotonin transporter0303
Sodium-dependent dopamine transporter0303
Nuclear receptor subfamily 3 group C member 3 011011
Ataxin-2100010
Sigma non-opioid intracellular receptor 10404
Transporter010112
Thrombopoietin1001
caspase 7, apoptosis-related cysteine protease3003
caspase-33003
Histone H2A.x4004
Spike glycoprotein0011
Replicase polyprotein 1ab0011
atrial natriuretic peptide receptor 1 precursor1001
atrial natriuretic peptide receptor 2 precursor4004
serine/threonine-protein kinase mTOR isoform 15005
Transmembrane protease serine 20011
Procathepsin L0011
Muscarinic acetylcholine receptor M209110
Muscarinic acetylcholine receptor M40909
Muscarinic acetylcholine receptor M5011011
Alpha-2A adrenergic receptor016320
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Cytochrome P450 2D6010111
Muscarinic acetylcholine receptor M1011213
Alpha-2B adrenergic receptor016219
Histamine H2 receptor0404
Trypanothione reductase0202
Histamine H1 receptor0101
Trypanothione reductase0101
D(1A) dopamine receptor4004
Proteasome subunit alpha type-60011
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Envelope glycoprotein0033
Angiotensin-converting enzyme 2 0011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Beta-1 adrenergic receptor 0124
Alpha-1B adrenergic receptor 0011
Membrane primary amine oxidase 0101
Solute carrier family 22 member 30202
Alpha-1A adrenergic receptor0112
Amine oxidase [flavin-containing] A0101
Amine oxidase [flavin-containing] B0101
Adenosine receptor A2b0011
Adenosine receptor A2a0013
Alpha-2B adrenergic receptor0001
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Nischarin0202
Nischarin0202
Sodium- and chloride-dependent creatine transporter 10101
aryl hydrocarbon receptor7007
Deoxycytidine kinase0001
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
endonuclease IV1001
15-lipoxygenase, partial4004
polyunsaturated fatty acid lipoxygenase ALOX122002
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
Epidermal growth factor receptor0101
Glutamate receptor 11214
Glutamate receptor 31214
Glutamate receptor 41214
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Potassium voltage-gated channel subfamily A member 50101
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Potassium voltage-gated channel subfamily A member 10101
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Sodium channel protein type 5 subunit alpha0404
Potassium voltage-gated channel subfamily D member 20101
Caspase-72002
caspase-32002
ras-related protein Rab-9A4004
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Potassium channel subfamily K member 20101
Cytochrome P450 2C80202
Dipeptidyl peptidase 40101
Gamma-aminobutyric acid receptor subunit alpha-10314
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20314
Acetylcholinesterase0101
Prostaglandin G/H synthase 10101
Potassium voltage-gated channel subfamily C member 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30213
Gamma-aminobutyric acid receptor subunit alpha-50314
Cytochrome P450 2C190314
Gamma-aminobutyric acid receptor subunit alpha-30314
Gamma-aminobutyric acid receptor subunit alpha-20314
Gamma-aminobutyric acid receptor subunit beta-20314
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit epsilon0202
Gastrin/cholecystokinin type B receptor 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Gamma-aminobutyric acid receptor subunit alpha-60213
Cytochrome P450 1B10202
Sigma non-opioid intracellular receptor 10303
Transporter0303
Beta-2 adrenergic receptor0214
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit theta0202
GLS protein100010
activating transcription factor 64004
Cytochrome P450 1A2 0202
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
bromodomain adjacent to zinc finger domain 2B3003
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
Histone deacetylase 30303
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit beta-10011
Histone deacetylase 40303
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
TAR DNA-binding protein 434004
Histone deacetylase 10303
Sterol O-acyltransferase 10011
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit pi0011
Histone deacetylase 70303
Histone deacetylase 20303
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
Histone deacetylase 80303
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Histone deacetylase 60303
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90303
Histone deacetylase 50303
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
Metabotropic glutamate receptor 80202
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Glutathione reductase, mitochondrial0404
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Integrin beta-31012
Integrin alpha-IIb1012
ATP-citrate synthase 0101
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10213
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10303
Glutamate receptor ionotropic, NMDA 2A0303
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0303
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, kainate 50101
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0202
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, Glutamine Binding Protein0011
peripheral myelin protein 22 isoform 14004
flap endonuclease 13003
Asc-type amino acid transporter 10101
Glycine receptor subunit alpha-10022
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10607
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
POU domain, class 2, transcription factor 10002
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Purine nucleoside phosphorylase0001
Adenosylhomocysteinase0102
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
ClpP2002
NFKB1 protein, partial1001
M-phase phosphoprotein 85005
Solute carrier family 22 member 80001
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
DNA polymerase iota isoform a (long)4004
Amyloid-beta precursor protein0202
Sodium/myo-inositol cotransporter 20101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Cationic amino acid transporter 30101
Potassium voltage-gated channel subfamily KQT member 10101
Cysteinyl leukotriene receptor 10101
interleukin 82002
Cytochrome P450 1A10101
Myeloperoxidase0303
Cytochrome P450 1A20314
Cholinesterase0101
Cytochrome P450 2C11 0101
Aromatase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Acetylcholinesterase 0101
Mu-type opioid receptor0202
Nociceptin receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear receptor ROR-gamma3115
Nuclear factor erythroid 2-related factor 20001
Palmitoleoyl-protein carboxylesterase NOTUM0101
Carboxylic ester hydrolase 0101
Acetylcholinesterase0101
Cholinesterase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Rap guanine nucleotide exchange factor 41001
Smad34004
Neuronal acetylcholine receptor subunit alpha-40213
Transient receptor potential cation channel subfamily A member 10011
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Acetylcholine receptor subunit gamma0213
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50101
Neuronal acetylcholine receptor subunit alpha-40101
Muscarinic acetylcholine receptor M20101
Acetylcholine receptor subunit beta0213
Cytochrome P450 2A60314
Translocator protein0101
Neuronal acetylcholine receptor subunit beta-20213
Cytochrome P450 2A50101
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit beta-40213
Muscarinic acetylcholine receptor M40101
Neuronal acetylcholine receptor subunit alpha-30213
Delta-type opioid receptor0101
Neuronal acetylcholine receptor subunit alpha-70224
Neuronal acetylcholine receptor subunit alpha-40213
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Acetylcholine receptor subunit epsilon0011
Neuronal acetylcholine receptor subunit beta-30112
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
Transient receptor potential cation channel subfamily A member 10011
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
FAD-linked sulfhydryl oxidase ALR0001
Glucose-6-phosphate 1-dehydrogenase0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
UDP-glucuronosyltransferase 1A40001
Adenosine receptor A10103
Vasopressin V2 receptor0112
Oxytocin receptor0224
Vasopressin V1a receptor0101
Vasopressin V1a receptor0325
Vasopressin V1b receptor0112
Vasopressin V1b receptor0101
Oxytocin receptor0101
Oxytocin receptor0011
Vasopressin V2 receptor 0101
Quinolone resistance protein NorA0101
Beta-adrenergic receptor kinase 10101
Potassium voltage-gated channel subfamily A member 30101
Beta-adrenergic receptor kinase 10112
Substance-P receptor0101
Rhodopsin kinase GRK10101
G protein-coupled receptor kinase 50101
G protein-coupled receptor kinase 50101
P2X purinoceptor 40101
Rhodopsin kinase GRK10101
ATPase family AAA domain-containing protein 54004
Beta-adrenergic receptor kinase 10001
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Plasma kallikrein0003
Alkaline phosphatase, tissue-nonspecific isozyme0202
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Intestinal-type alkaline phosphatase0202
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Carbonic anhydrase0003
Carbonic anhydrase0003
E3 ubiquitin-protein ligase XIAP0101
SLC16A10 protein0003
Carbonic anhydrase 0003
Carbonic anhydrase0003
Carbonic anhydrase0003
Large neutral amino acids transporter small subunit 1 0101
Carbonic anhydrase 0003
Monocarboxylate transporter 100003
Carbonic anhydrase 150104
Phospholipase A-2-activating protein0202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Albumin0011
Beta-2 adrenergic receptor0213
Adenosine receptor A30314
Beta-3 adrenergic receptor0213
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Endothelin-1 receptor0112
5-hydroxytryptamine receptor 1B0213
Adenosine receptor A2a0112
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Cholecystokinin receptor type A0112
Beta-1 adrenergic receptor0101
Mu-type opioid receptor0112
Delta-type opioid receptor0112
Kappa-type opioid receptor0112
Sodium/bile acid cotransporter0101
Nuclear receptor subfamily 2 group E member 10022
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Voltage-dependent calcium channel subunit alpha-2/delta-20101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 2A0101
D(2) dopamine receptor0101
5-hydroxytryptamine receptor 2B0101
5-hydroxytryptamine receptor 1A0101
nonstructural protein 12002
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
Rap guanine nucleotide exchange factor 31001
Transcriptional activator protein LuxR0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Melanocortin receptor 50202
Nrf21001
pregnane X receptor3003
Caspase 6, apoptosis-related cysteine peptidase0001
apical membrane antigen 1, AMA11001
hypothetical protein, conserved1001
glucocerebrosidase1001
toll-like receptor 90101
caspase recruitment domain family, member 150101
thyrotropin-releasing hormone receptor2002
nuclear receptor subfamily 1, group I, member 21001
histone deacetylase 9 isoform 31001
importin subunit beta-1 isoform 11001
neurotensin receptor type 10011
receptor-interacting serine/threonine-protein kinase 2 isoform 10101
nuclear factor NF-kappa-B p105 subunit isoform 11001
serine/threonine-protein kinase PLK11001
heat shock protein HSP 90-alpha isoform 20001
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
Alpha-synuclein1102
heat shock protein 90, putative0001
large T antigen0101
Beta lactamase (plasmid)0101
Chain A, Nuclear Receptor ROR-beta0101
thioredoxin glutathione reductase2002
Parkin1001
Ornithine decarboxylase0001
Ornithine decarboxylase0001
60 kDa chaperonin0101
Retinoic acid receptor alpha0227
60 kDa heat shock protein, mitochondrial0101
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Retinoic acid receptor gamma0123
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
10 kDa heat shock protein, mitochondrial0101
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
Cannabinoid receptor 10101
Diamine acetyltransferase 10001
Thialysine N-epsilon-acetyltransferase0001
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Dihydrofolate reductase0202
Stromelysin-10101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Polyphenol oxidase 20001
Tubulin--tyrosine ligase0101
Taste receptor type 2 member 140001
Chain A, Arginase 10101
Cocaine esterase0101
UDP-glucuronosyltransferase 1A90001
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 1-60001
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]