methylphenidate has been researched along with Asperger Syndrome in 7 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Asperger Syndrome: A disorder beginning in childhood whose essential features are persistent impairment in reciprocal social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities. These symptoms may limit or impair everyday functioning. (From DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to assess the response of anxiety and depression symptoms to methylphenidate (MPH) treatment in patients with Asperger syndrome (AS) combined with attention deficit/hyperactivity disorder (ADHD)." | 9.24 | The effect of methylphenidate on anxiety and depression symptoms in patients with Asperger syndrome and comorbid attention deficit/hyperactivity disorder. ( Golubchik, P; Rapaport, M; Weizman, A, 2017) |
| "The objective of this study was to assess the response of anxiety and depression symptoms to methylphenidate (MPH) treatment in patients with Asperger syndrome (AS) combined with attention deficit/hyperactivity disorder (ADHD)." | 5.24 | The effect of methylphenidate on anxiety and depression symptoms in patients with Asperger syndrome and comorbid attention deficit/hyperactivity disorder. ( Golubchik, P; Rapaport, M; Weizman, A, 2017) |
| "This report examined the effect of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity in a secondary analysis of RUPP Autism Network data." | 5.14 | Positive effects of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity. ( Aman, MG; Arnold, LE; Ghuman, J; Jahromi, LB; Kasari, CL; Kustan, E; Lee, LS; McCracken, JT; McDougle, CJ; Posey, DJ; Ritz, L; Scahill, L; Tierney, E; Vitiello, B; Witwer, A, 2009) |
| "We report on a case of severe chronic pain in a child with undiagnosed comorbid autism spectrum disorder and attention deficit hyperactivity disorder, where significant improvements in pain and function occurred following methylphenidate medication and parental behavioural training." | 2.58 | A case report and literature review of autism and attention deficit hyperactivity disorder in paediatric chronic pain. ( Bölte, S; von Heijne, M; Wicksell, RK; Wiwe Lipsker, C, 2018) |
| "Asperger syndrome is associated with various dysfunctional and problematic behaviors, in addition to the core features of communication and social skills dysfunction that define these conditions." | 2.44 | [Pharmacologic treatment of Asperger syndrome]. ( Yamada, S, 2007) |
| "Childhood narcolepsy is associated with various emotional, behavioural and cognitive dysfunctions as well as with psychiatric and neurodevelopmental disorders: anxiety, depression, attention deficit hyperactivity disorder and psychosis." | 1.48 | Childhood narcolepsy and autism spectrum disorders: four case reports. ( Dudova, I; Hrdlicka, M; Mohaplova, M; Nevsimalova, S; Prihodova, I, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Golubchik, P | 1 |
| Rapaport, M | 1 |
| Weizman, A | 1 |
| Wiwe Lipsker, C | 1 |
| von Heijne, M | 1 |
| Bölte, S | 1 |
| Wicksell, RK | 1 |
| Prihodova, I | 1 |
| Dudova, I | 1 |
| Mohaplova, M | 1 |
| Hrdlicka, M | 1 |
| Nevsimalova, S | 1 |
| Jahromi, LB | 1 |
| Kasari, CL | 1 |
| McCracken, JT | 2 |
| Lee, LS | 1 |
| Aman, MG | 2 |
| McDougle, CJ | 2 |
| Scahill, L | 2 |
| Tierney, E | 2 |
| Arnold, LE | 2 |
| Vitiello, B | 2 |
| Ritz, L | 1 |
| Witwer, A | 1 |
| Kustan, E | 1 |
| Ghuman, J | 1 |
| Posey, DJ | 1 |
| Roy, M | 1 |
| Dillo, W | 1 |
| Bessling, S | 1 |
| Emrich, HM | 1 |
| Ohlmeier, MD | 1 |
| Yamada, S | 1 |
| Sukhodolsky, DG | 1 |
| Gadow, KD | 1 |
| Williams White, S | 1 |
| Lecavalier, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Methylphenidate for Hyperactivity and Impulsiveness in Children and Adolescents With Pervasive Developmental Disorders[NCT00025779] | 60 participants | Interventional | 2001-10-31 | Completed | |||
| Neural Mechanisms of CBT for Anxiety in Children With Autism: Randomized Controlled Trial[NCT02725619] | 70 participants (Actual) | Interventional | 2016-04-30 | Completed | |||
| Neural Mechanisms of Cognitive-Behavioral Therapy for Anxiety in Children With Autism Spectrum Disorder: A Pilot Study[NCT02225808] | 10 participants (Actual) | Interventional | 2014-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for methylphenidate and Asperger Syndrome
| Article | Year |
|---|---|
A case report and literature review of autism and attention deficit hyperactivity disorder in paediatric chronic pain.
Topics: Acceptance and Commitment Therapy; Asperger Syndrome; Attention Deficit Disorder with Hyperactivity; | 2018 |
[Pharmacologic treatment of Asperger syndrome].
Topics: Aggression; Antidepressive Agents, Second-Generation; Asperger Syndrome; Child; Communication; Depre | 2007 |
2 trials available for methylphenidate and Asperger Syndrome
| Article | Year |
|---|---|
The effect of methylphenidate on anxiety and depression symptoms in patients with Asperger syndrome and comorbid attention deficit/hyperactivity disorder.
Topics: Adolescent; Anxiety; Asperger Syndrome; Attention Deficit Disorder with Hyperactivity; Central Nervo | 2017 |
Positive effects of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity.
Topics: Adolescent; Asperger Syndrome; Autistic Disorder; Central Nervous System Stimulants; Child; Child De | 2009 |
3 other studies available for methylphenidate and Asperger Syndrome
| Article | Year |
|---|---|
Childhood narcolepsy and autism spectrum disorders: four case reports.
Topics: Age of Onset; Antidepressive Agents; Anxiety Disorders; Asperger Syndrome; Attention Deficit Disorde | 2018 |
Effective methylphenidate treatment of an adult Aspergers Syndrome and a comorbid ADHD: a clinical investigation with fMRI.
Topics: Adult; Asperger Syndrome; Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous Syst | 2009 |
Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.
Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety; Asperger Syndrome; Attention Deficit Disorder | 2008 |
Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.
Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety; Asperger Syndrome; Attention Deficit Disorder | 2008 |
Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.
Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety; Asperger Syndrome; Attention Deficit Disorder | 2008 |
Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.
Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety; Asperger Syndrome; Attention Deficit Disorder | 2008 |
Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.
Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety; Asperger Syndrome; Attention Deficit Disorder | 2008 |
Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.
Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety; Asperger Syndrome; Attention Deficit Disorder | 2008 |
Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.
Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety; Asperger Syndrome; Attention Deficit Disorder | 2008 |
Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.
Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety; Asperger Syndrome; Attention Deficit Disorder | 2008 |
Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.
Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety; Asperger Syndrome; Attention Deficit Disorder | 2008 |