Acidosis, Renal Tubular Type IV

A selective aldosterone deficiency resulting from diminished RENIN-generated ANGIOTENSIN II, a key stimulus to aldosterone secretion. Previously, it was called type IV renal tubular acidosis.

Synonym
Renal Tubular Acidosis, Type IV
Hyporeninemic Hypoaldosteronism
Type IV Renal Tubular Acidosis
Hypoaldosteronism
Hypoaldosteronism, Hyporeninemic
Acidosis, Renal Tubular Type IV

Excerpt	Reference
"The hypoaldosteronism is associated with selective unresponsiveness of aldosterone to angiotensin II (AII) and an atrophy of the zona glomerulosa."	( Azukizawa, S; Kaneko, M; Kigoshi, T; Morimoto, S; Nakano, S; Uchida, K, 1991)
"Pseudohypoaldosteronism is a hereditary salt-wasting syndrome usually seen in infancy with weight loss, dehydration, and failure to thrive."	( Aladjem, M; Bistritzer, T; Cotariu, D; Evans, S; Goldberg, M, 1994)
"Hyporeninaemic hypoaldosteronism is managed with a low potassium diet and a low dose loop or thiazide diuretic."	( Murray, M; Xu, B, 2009)
"Isolated hypoaldosteronism is an autosomal recessive inherited disorder of terminal aldosterone synthesis, leading to selective aldosterone deficiency."	( Collinet, E; Gay, C; Morel, Y; Pelissier, P; Pugeat, M; Richard, O; Stephan, JL, 2012)
"Hypoaldosteronism is a clinical condition resulting from inadequate stimulation of aIdosterone secretion (hyporeninemic hypoaIdosteronism), defects in adrenal synthesis of aldosterone (hyperreninemic hypoaldosteronism), or resistance to the peripheral action of this hormone (pseudohypoaldosteronism)."	( Krysiak, R; Okopień, B, 2012)
"Primary hypoaldosteronism is a rare inborn disorder with life-threatening symptoms in newborns and infants due to an aldosterone synthase defect."	( Holterhus, PM; Katschnig, C; Konrad, D; l'Allemand, D; Lang-Muritano, M; Phan-Hug, F; Ruecker, B; Schoenle, EJ; Spanaus, K; Welzel, M, 2015)
"Hypoaldosteronism is associated with either insufficient aldosterone production or aldosterone resistance (pseudohypoaldosteronism)."	( Gurbuz, F; Kotan, LD; Tastan, M; Topaloglu, AK; Turan, I; Yuksel, B, 2018)
"Hyporeninemic hypoaldosteronism is the mechanism causing the electrolyte disbalance reported in patients with RMND1 mutations, and can be treated."	( Beck, BB; Dijkman, H; Gracchi, V; Kömhoff, M; Monnens, L, 2024)

Excerpt	Reference
"Hyporeninemic hypoaldosteronism has mainly been described in patients with diabetes mellitus."	( Yamaguchi, M, 1994)
"Hyperreninaemic hypoaldosteronism has never been reported in the dog."	( Lobetti, RG, 1998)
"Hyperreninemic hypoaldosteronism has been described in critically ill patients."	( Charbonneau, P; Daubin, C; du Cheyron, D; Lesage, A; Ramakers, M, 2003)
"Chronic hyporeninemic hypoaldosteronism has been found in many cases of methylmalonic acidemia, hyperkalemia and renal tubular acidosis type 4."	( Donati, MA; Gasperini, S; Pasquini, E; Pela, I, 2006)

Excerpt	Reference
"Hyporeninemic hypoaldosteronism could be demonstrated in 4 patients during the administration of CSA."	( Grabensee, B; Heering, P, 1991)
"Hyporeninemic hypoaldosteronism was disclosed on the basis of a lack of response of plasma renin activity to furosemide administration or tilting with marked hypotension and a subnormal response of aldosterone to furosemide stimulation, tilting, angiotensin II infusion and ACTH administration, as well as increased vascular responsiveness to angiotensin II infusion."	( Inaba, M; Ishii, J; Itabashi, A; Katayama, S; Maruno, Y; Morimoto, S; Omoto, A, 1989)
"Hyperreninemic hypoaldosteronism was diagnosed in a 34-year-old woman with hypertension who was receiving captopril therapy."	( Maeda, T; Ohchi, N; Rikitake, O; Sakemi, T; Sanai, T, 1988)
"A case of hyporeninaemic hypoaldosteronism in a young girl with treated Graves' disease presenting as hyperkalaemia is described."	( Chan, NN; Chan, WB; Chow, CC; Ng, CW; So, WY, 2003)
"Hyporeninemic hypoaldosteronism is the mechanism causing the electrolyte disbalance reported in patients with RMND1 mutations, and can be treated."	( Beck, BB; Dijkman, H; Gracchi, V; Kömhoff, M; Monnens, L, 2024)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	46 (23.12)	23.3326
1990's	64 (32.16)	12.5806
2000's	40 (20.10)	18.1394
2010's	33 (16.58)	28.8240
2020's	16 (8.04)	9.53

Drug	Relationship Strength	Studies	Trials
ammonium hydroxide	low	2	0
chlorine	low	5	0
hydrogen carbonate	medium	7	1
dalteparin	low	1	0
histamine	low	1	0
urea	medium	1	1
acetazolamide	low	1	0
atenolol	low	1	0
azathioprine	low	1	0
ethenzamide	low	1	0
fluconazole	low	1	0
furosemide	low	13	0
ethidium	low	1	0
hydrochlorothiazide	low	1	0
ibuprofen	low	3	0
metoclopramide	low	1	0
mitotane	low	1	0
apnea	low	1	0
nifedipine	low	1	0
triamterene	low	2	0
mitomycin	low	1	0
corticosterone	low	4	0
spironolactone	low	6	0
aldosterone	medium	99	4
fluprednisolone	low	1	0
desoxycorticosterone	low	6	0
arginine	low	1	0
pregnenolone	low	1	0
calcium gluconate	low	1	0
betamethasone	low	1	0
18-hydroxycorticosterone	low	5	0
megestrol acetate	low	1	0
vancomycin	low	1	0
glycyrrhizic acid	low	1	0
amiloride	low	2	0
iodinated glycerol	low	3	0
sodium sulfate	low	1	0
silver nitrate	low	1	0
ammonium chloride	low	1	0
triamcinolone	low	1	0
fludrocortisone	medium	29	2
captopril	low	4	0
18-hydroxydeoxycorticosterone	low	1	0
chymosin	low	1	0
9-fluoroprednisolone	low	1	0
naproxen	low	1	0
angiotensin ii	medium	14	1
cortisone	low	5	0
fludrocortisone acetate	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	2	0
sodium bicarbonate	low	2	0
citraconic acid	low	1	0
17-ketosteroids	low	1	0
dinoprostone	low	1	0
amphotericin b	low	1	0
naloxone	low	1	0
iloprost	low	1	0
12-hydroxy-5,8,10,14-eicosatetraenoic acid	low	1	0
lisinopril	low	1	0
ramipril	low	1	0
enalapril	low	1	0
fumarates	low	1	0
aluminum oxide	low	1	0
amphotericin a	low	1	0
losartan potassium	low	1	0
deoxycortone pivalate	low	1	0
pituitrin	low	2	0
9-fluorocortisone	low	1	0
cosyntropin	low	1	0
atrial natriuretic factor	low	1	0
adrenocorticotropin zinc	low	1	0
cobicistat	low	1	0
angiotensin i	low	1	0
adrenomedullin	low	1	0
vitamin b 12	low	1	0
cyclosporine	low	2	0

Protein Targets (731)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	9	0	0	9
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	5	0	0	5
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	4	0	4
thioredoxin reductase	14	0	0	14
GALC protein	5	0	0	5
GLI family zinc finger 3	22	0	0	22
nuclear receptor subfamily 1, group I, member 3	15	0	0	15
cytochrome P450 family 3 subfamily A polypeptide 4	14	0	0	14
glucocorticoid receptor [Homo sapiens]	29	0	0	29
retinoic acid nuclear receptor alpha variant 1	20	0	0	20
retinoid X nuclear receptor alpha	19	0	0	19
estrogen-related nuclear receptor alpha	21	0	0	21
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
arylsulfatase A	9	0	0	9
Carbonic anhydrase	0	1	0	1
euchromatic histone-lysine N-methyltransferase 2	21	0	0	21
Bloom syndrome protein isoform 1	8	0	0	8
thyroid hormone receptor beta isoform a	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 1	21	0	0	21
geminin	21	0	0	21
peripheral myelin protein 22	8	0	0	8
survival motor neuron protein isoform d	9	0	0	9
muscleblind-like protein 1 isoform 1	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	9	2	2	13
ATP-binding cassette sub-family C member 3	0	19	0	19
Multidrug resistance-associated protein 4	0	19	0	20
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	5	0	5
Carbonic anhydrase 12	0	4	1	9
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	26	0	26
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	3	0	3
Carbonic anhydrase 1	0	8	1	15
Carbonic anhydrase 2	0	9	1	16
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	5	0	5
Carbonic anhydrase 3	0	4	1	8
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	6	1	8
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2D6	0	8	0	8
Cytochrome P450 2A6	0	1	0	1
Cytochrome P450 2C9	0	15	0	15
5-hydroxytryptamine receptor 2A	0	4	0	4
Androgen receptor	0	7	0	8
Gamma-aminobutyric acid receptor subunit beta-1	9	2	2	13
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	9	2	2	13
Gamma-aminobutyric acid receptor subunit gamma-2	9	2	2	13
Gamma-aminobutyric acid receptor subunit alpha-5	9	2	2	13
Gamma-aminobutyric acid receptor subunit alpha-3	9	2	2	13
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
Carbonic anhydrase 4	0	8	1	12
Carbonic anhydrase 6	0	4	1	8
Gamma-aminobutyric acid receptor subunit gamma-1	9	2	2	13
Gamma-aminobutyric acid receptor subunit alpha-2	9	2	2	13
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	3	0	4
Serum paraoxonase/arylesterase 1	0	2	0	2
Dipeptidyl peptidase 4	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	9	2	2	13
Gamma-aminobutyric acid receptor subunit gamma-3	9	2	2	13
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	9	2	2	13
Adenosine receptor A2a	0	4	0	5
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium-dependent serotonin transporter	0	3	0	3
Delta-type opioid receptor	0	4	1	6
Cytochrome P450 2C19	0	5	0	5
Delta-type opioid receptor	0	4	2	6
Mu-type opioid receptor	0	6	2	8
Carbonic anhydrase 5A, mitochondrial	0	6	1	11
Carbonic anhydrase	0	5	0	6
Kappa-type opioid receptor	0	3	1	4
Carbonic anhydrase 7	0	4	1	8
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	3	1	4
Carbonic anhydrase	0	1	0	3
D(2) dopamine receptor	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	9	2	2	13
Gamma-aminobutyric acid receptor subunit beta-3	9	2	2	13
Gamma-aminobutyric acid receptor subunit beta-2	9	2	2	13
Cholinesterase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	5	2	7
Fatty-acid amide hydrolase 1	0	2	0	2
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	2
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase 9	0	5	1	10
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	3
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	5
GABA theta subunit	9	2	2	13
Canalicular multispecific organic anion transporter 1	0	18	0	18
Carbonic anhydrase 4	0	2	0	3
Carbonic anhydrase 15	0	3	0	5
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	4	0	7
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	9	2	2	13
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase 14	0	4	1	9
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	5	1	10
AR protein	32	0	0	32
nuclear factor erythroid 2-related factor 2 isoform 2	9	0	0	9
Sex hormone-binding globulin	0	0	5	5
Corticosteroid-binding globulin	0	5	0	5
Mineralocorticoid receptor	0	3	3	7
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	4
Guanine nucleotide-binding protein G	3	0	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	13	0	0	13
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, HADH2 protein	9	0	0	9
Chain B, HADH2 protein	9	0	0	9
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
acid sphingomyelinase	1	0	0	1
acetylcholinesterase	6	0	0	6
TDP1 protein	21	0	0	21
aldehyde dehydrogenase 1 family, member A1	10	0	0	10
thyroid stimulating hormone receptor	8	0	0	8
regulator of G-protein signaling 4	6	0	0	6
estrogen nuclear receptor alpha	31	0	0	31
glucocerebrosidase	3	0	0	3
alpha-galactosidase	3	0	0	3
cytochrome P450 2D6 isoform 1	3	0	0	3
lysosomal alpha-glucosidase preproprotein	2	0	0	2
cytochrome P450 2C19 precursor	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
thyroid hormone receptor beta isoform 2	17	0	0	17
huntingtin isoform 2	1	0	0	1
lamin isoform A-delta10	19	0	0	19
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	5	0	7
Prothrombin	0	2	0	2
Coagulation factor X	0	1	0	1
Plasminogen	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	1	0	1
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	1	0	2
Vitamin K-dependent protein C	0	1	0	1
Cellular tumor antigen p53	15	0	0	15
Urokinase-type plasminogen activator	0	2	0	2
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Adenosine receptor A2a	0	3	1	4
Trypsin-3	0	1	0	1
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	3	0	3
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	4	0	5
Solute carrier family 22 member 2	0	5	0	6
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
Chain A, Cruzipain	4	0	0	4
interleukin 8	3	0	0	3
phosphopantetheinyl transferase	7	0	0	7
GLS protein	7	0	0	7
farnesoid X nuclear receptor	16	0	0	16
peroxisome proliferator-activated receptor delta	15	0	0	15
vitamin D (1,25- dihydroxyvitamin D3) receptor	18	0	0	18
tumor necrosis factor	3	0	0	3
vitamin D3 receptor isoform VDRA	6	0	0	6
Nuclear receptor ROR-gamma	6	0	0	6
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	4
DNA polymerase kappa isoform 1	3	0	0	3
histone acetyltransferase KAT2A isoform 1	4	0	0	4
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	5	0	5
Type-2 angiotensin II receptor	0	2	0	2
ATAD5 protein, partial	6	0	0	6
Microtubule-associated protein tau	7	0	0	7
D(1A) dopamine receptor	5	0	0	5
neuropeptide S receptor isoform A	2	0	0	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	6	0	0	6
chromobox protein homolog 1	14	0	0	14
flap endonuclease 1	3	0	0	3
DNA polymerase iota isoform a (long)	10	0	0	10
muscarinic acetylcholine receptor M1	7	0	0	7
lethal factor (plasmid)	5	0	0	5
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	7	0	0	7
Beta-1 adrenergic receptor	0	1	2	4
Fatty acid-binding protein, liver	0	2	0	2
Urease	0	1	0	1
Beta-2 adrenergic receptor	0	4	2	6
Beta-1 adrenergic receptor	0	4	2	6
Beta-3 adrenergic receptor	0	2	2	4
5-hydroxytryptamine receptor 1A	0	4	2	7
Alpha-1D adrenergic receptor	0	1	1	3
Alpha-1A adrenergic receptor	0	2	2	5
Alpha-1B adrenergic receptor	0	1	1	3
TAR DNA-binding protein 43	7	0	0	7
Beta-2 adrenergic receptor	0	2	2	6
Atrial natriuretic peptide receptor 1	0	0	1	1
Atrial natriuretic peptide receptor 1	0	0	1	1
Chain A, Ferritin light chain	2	0	0	2
RAR-related orphan receptor gamma	18	0	0	18
SMAD family member 2	9	0	0	9
Fumarate hydratase	5	0	0	5
SMAD family member 3	9	0	0	9
thioredoxin glutathione reductase	4	0	0	4
EWS/FLI fusion protein	5	0	0	5
pregnane X nuclear receptor	17	0	0	17
G	8	0	0	8
polyprotein	5	0	0	5
P53	1	0	0	1
peroxisome proliferator activated receptor gamma	12	0	0	12
IDH1	9	0	0	9
aryl hydrocarbon receptor	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	14	0	0	14
thyroid stimulating hormone receptor	5	0	0	5
activating transcription factor 6	5	0	0	5
v-jun sarcoma virus 17 oncogene homolog (avian)	11	0	0	11
Histone H2A.x	8	0	0	8
peripheral myelin protein 22 isoform 1	7	0	0	7
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
heat shock protein beta-1	8	0	0	8
cytochrome P450 3A4 isoform 1	9	0	0	9
M-phase phosphoprotein 8	5	0	0	5
Bile salt export pump	0	5	0	5
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Interferon beta	12	0	0	12
HLA class I histocompatibility antigen, B alpha chain	8	0	0	8
Glutamate receptor 2	10	0	0	10
Inositol hexakisphosphate kinase 1	8	0	0	8
ATPase family AAA domain-containing protein 5	6	0	0	6
Ataxin-2	7	0	0	7
Protein-arginine deiminase type-4	0	1	0	1
cytochrome P450 2C9, partial	8	0	0	8
pregnane X receptor	7	0	0	7
progesterone receptor	17	0	0	17
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	14	2	16
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
ORF73	0	0	1	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
15-lipoxygenase, partial	1	0	0	1
Thrombopoietin	3	0	0	3
Metallo-beta-lactamase type 2	0	1	1	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	6	1	7
Angiotensin-converting enzyme	0	6	0	7
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	4	0	4
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	3	0	3
Angiotensin-converting enzyme	0	4	0	4
Solute carrier family 15 member 1	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	2	0	2
Beta-lactamase class B VIM-2	0	1	1	2
Protease	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
nonstructural protein 1	5	0	0	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	10	0	0	10
mitogen-activated protein kinase 1	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
Solute carrier family 22 member 2	0	1	0	3
Solute carrier family 22 member 3	0	2	0	3
Solute carrier family 22 member 3	0	2	0	2
C-8 sterol isomerase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	0	4
endonuclease IV	3	0	0	3
dopamine D1 receptor	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Multidrug and toxin extrusion protein 1	0	4	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
USP1 protein, partial	5	0	0	5
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
nuclear receptor ROR-gamma isoform 1	6	0	0	6
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	2	4
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	3	1	4
Prostaglandin E2 receptor EP2 subtype	0	2	2	4
Prostacyclin receptor	0	4	2	6
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Solute carrier family 22 member 6	0	2	0	3
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	1	0	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	7	0	0	7
Spike glycoprotein	9	0	0	9
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Smad3	7	0	0	7
67.9K protein	7	0	0	7
Reverse transcriptase/RNaseH	0	1	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
apical membrane antigen 1, AMA1	2	0	0	2
cytochrome P450 2D6	6	0	0	6
unnamed protein product	0	1	0	1
transcriptional regulator ERG isoform 3	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	1	0	1
Rap guanine nucleotide exchange factor 3	2	0	0	2
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
ATP-dependent translocase ABCB1	0	5	0	5
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	2	0	2
Histone deacetylase 4	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Histone deacetylase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	1	3
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
heat shock protein 90, putative	0	0	0	1
likely tRNA 2'-phosphotransferase	0	1	0	1
estrogen receptor 2 (ER beta)	8	0	0	8
thyrotropin-releasing hormone receptor	1	0	0	1
Albumin	0	3	3	6
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	1	3
Adenosine receptor A1	0	1	0	1
Cytochrome P450 2J2	0	9	0	9
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Pancreatic alpha-amylase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
High mobility group protein B1	0	0	1	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
High mobility group protein B1	0	0	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 2	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Histamine H2 receptor	0	1	2	3
5-hydroxytryptamine receptor 1D	0	0	0	1
Histamine H1 receptor	0	1	2	3
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H1 receptor	0	2	2	4
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Histamine H2 receptor	4	0	1	5
Histamine H3 receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Equilibrative nucleoside transporter 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	2	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
Histamine H3 receptor	0	1	2	3
Hsf1 protein	0	0	2	2
cytochrome P450 2C9 precursor	4	0	0	4
Luciferase	4	0	0	4
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Epidermal growth factor receptor	0	1	0	1
Albumin	0	1	0	1
Albumin	0	0	2	2
Prostaglandin G/H synthase 1	0	3	0	3
Cholinesterase	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	5
UDP-glucuronosyltransferase 2B7	0	0	0	1
Acetylcholinesterase	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Caspase-1	0	3	0	3
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Aldo-keto reductase family 1 member C3	0	4	0	4
Caspase-3	0	2	0	2
Caspase-4	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	3
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	4
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Prostacyclin receptor	0	1	1	2
Prostaglandin D2 receptor	0	0	1	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Aldo-keto reductase family 1 member B10	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Myc proto-oncogene protein	0	1	0	1
Myeloperoxidase	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	2	0	2
Aldo-keto reductase family 1 member C2	0	3	0	3
Aldo-keto reductase family 1 member C1	0	3	0	3
Peroxisome proliferator-activated receptor alpha	2	0	0	2
Nicotinate phosphoribosyltransferase	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
bioA	0	0	0	1
DNA polymerase beta	1	0	0	1
5-hydroxytryptamine receptor 3E	0	0	1	1
5-hydroxytryptamine receptor 4	0	6	0	6
5-hydroxytryptamine receptor 3B	0	0	1	1
Alpha-2A adrenergic receptor	0	6	2	9
D(2) dopamine receptor	0	3	1	4
Alpha-1B adrenergic receptor	0	7	1	8
D	0	1	0	1
D(3) dopamine receptor	0	3	0	3
Alpha-2B adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	2	1	3
Alpha-2A adrenergic receptor	0	2	1	3
Alpha-1D adrenergic receptor	0	3	1	4
5-hydroxytryptamine receptor 3A	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	4	1	5
5-hydroxytryptamine receptor 2C	0	6	1	7
5-hydroxytryptamine receptor 1B	0	3	0	3
5-hydroxytryptamine receptor 1D	0	1	0	1
D(4) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 2B	0	6	1	7
Alpha-1A adrenergic receptor	0	7	1	8
5-hydroxytryptamine receptor 3A	0	0	1	1
Lactoperoxidase	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	2
5-hydroxytryptamine receptor 3D	0	0	1	1
5-hydroxytryptamine receptor 3C	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
caspase 7, apoptosis-related cysteine protease	3	0	0	3
caspase-3	3	0	0	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
glp-1 receptor, partial	3	0	0	3
PPM1D protein	1	0	0	1
Caspase-7	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
caspase-3	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Adenosine receptor A3	0	5	1	6
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent serotonin transporter	0	4	0	4
5-hydroxytryptamine receptor 6	0	4	1	5
Sodium-dependent dopamine transporter	0	2	0	2
Rap guanine nucleotide exchange factor 4	1	0	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Histidine decarboxylase	0	0	1	1
Adenosine receptor A1	0	3	0	3
Kappa-type opioid receptor	0	1	0	2
Kappa-type opioid receptor	0	1	2	3
Mu-type opioid receptor	0	3	2	6
Delta-type opioid receptor	0	3	2	6
Kappa-type opioid receptor	0	3	3	7
Mu-type opioid receptor	0	1	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Hormone-sensitive lipase	0	1	0	1
hypothetical protein, conserved	1	0	0	1
Parkin	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Potassium channel subfamily K member 2	0	0	1	1
Glutathione reductase, mitochondrial	0	2	0	2
Integrin beta-3	2	0	0	2
Muscarinic acetylcholine receptor M2	0	1	1	3
Muscarinic acetylcholine receptor M4	0	0	0	1
Integrin alpha-IIb	2	0	0	2
Muscarinic acetylcholine receptor M5	0	0	0	1
Muscarinic acetylcholine receptor M1	0	1	1	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Phospholipase A2, membrane associated	0	0	0	1
Muscarinic acetylcholine receptor M3	0	1	1	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Inositol monophosphatase 1	2	0	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Leukotriene B4 receptor 1	0	0	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Potassium channel subfamily K member 2	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	3
Alpha-2B adrenergic receptor	0	0	1	2
Beta-1 adrenergic receptor	0	2	1	4
Alpha-2C adrenergic receptor	0	1	2	4
D(1A) dopamine receptor	0	1	1	2
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Vasopressin V1a receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Vpr	1	0	0	1
Estrogen receptor	0	2	1	3
Progesterone receptor	0	2	1	3
Androgen receptor	0	2	1	3
Estrogen receptor beta	0	1	1	2
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, PAPAIN	1	0	0	1
putative alpha-glucosidase	1	0	0	1
pyruvate kinase	1	0	0	1
Janus kinase 2 (a protein tyrosine kinase)	0	1	0	1
histone deacetylase 9 isoform 3	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Cathepsin G	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Cyclin-dependent kinase 4	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
G1/S-specific cyclin-D1	0	1	0	1
Casein kinase I isoform alpha	0	1	0	1
Casein kinase I isoform delta	0	1	0	1
Casein kinase I isoform epsilon	0	1	0	1
Caspase-7	1	0	0	1
Pteridine reductase 1	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Acidosis, Renal Tubular Type IV

Synonyms(6)

Research Excerpts

Overview

Context

Treatment

Research

Studies (199)

Protein Targets (731)

Acidosis, Renal Tubular Type IV

Synonyms(6)

Research Excerpts

Overview

Context

Treatment

Research

Studies (199)

Drugs Studied (88)

Protein Targets (731)