Page last updated: 2024-09-27

Jactatio Capitis Nocturna

Parasomnias characterized by behavioral abnormalities that occur during the transition between wakefulness and sleep (or between sleep and wakefulness).

Synonyms(12)

Synonym
Transitional Disorders, Sleep-Wake
Jactatio Capitis Nocturna
Transition Disorders, Sleep-Wake
Somnolescent Starts
Rhythmic Movement Disorders, Nocturnal
Sleep Starts
Movement Disorders, Rhythmic Nocturnal
Sleep Talking
Nocturnal Sleep Head Banging
Sleep-Wake Transition Disorders
Sleep-Wake Transitional Disorders
Nocturnal Leg Cramps

Research Excerpts

Overview

ExcerptReference
"Nocturnal leg cramps is a common and troublesome problem in elderly individuals, and their etiology is unknown."( Chan, P; Chen, YJ; Huang, TY; Huang, WP; Liu, YC, 1998)
"Nocturnal leg cramps are common and troublesome, especially in later life, and have a significant impact on quality of life, particularly sleep quality."( Mulkerrin, EC; O'Keeffe, ST; Rabbitt, L, 2016)
"Although nocturnal leg cramps are common, little research is available about their impact on quality of life."( Chauveau, N; Haller, DM; Heimer, O; Kaiser, C; Maisonneuve, H; Sebo, P; Zaim, A, 2022)

Treatment

ExcerptReference
"Quinine is a common treatment for nocturnal leg cramps but has potential side effects."( Coppin, RJ; Little, PS; Wicke, DM, 2005)
"Frequent and painful nocturnal leg cramps (NLC) require an effective therapy to improve quality of life and sleep performance in patients."( Baurecht, W; Diener, HC, 2019)

Research

Studies (64)

TimeframeStudies, This Condition (%)All Conditions %
pre-19904 (6.25)23.3326
1990's1 (1.56)12.5806
2000's28 (43.75)18.1394
2010's25 (39.06)28.8240
2020's6 (9.38)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0medium11
melatonin0low10
niacinamide0low10
niacin0low10
theophylline0low40
aspirin0low10
caffeine0low10
verapamil0low10
chloral hydrate0medium11
clonazepam0low30
diazepam0low10
donepezil0low10
gabapentin0medium21
lidocaine0low10
methocarbamol0low10
nafronyl0low10
levodopa0low10
leucine0low10
methionine0low10
pyrroles0low10
aminophylline0low20
hesperidin0low10
d-alpha tocopherol0low10
trolamine salicylate0low10
diltiazem0medium11
atorvastatin0low10
niaprazine0low10
limptar0low20
acetogenins0low10
cocaine0low10
D-fructopyranose0low10
quinine0medium323
biochanin a0low10
genistein0low10
coenzyme q100low10
topiramate0low10
fluvoxamine0low10
ubiquinone0low10
cardiovascular agents0low20
piperidines0low10
ascorbic acid0low10
phytoestrogens0low10

Protein Targets (740)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
thioredoxin reductase100010
USP1 protein, partial4004
Microtubule-associated protein tau5005
lamin isoform A-delta10130013
ATP-binding cassette sub-family C member 3013013
Multidrug resistance-associated protein 4013013
Bile salt export pump017017
Canalicular multispecific organic anion transporter 1012012
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase1001
RAR-related orphan receptor gamma110011
GLI family zinc finger 3110011
AR protein150015
thioredoxin glutathione reductase2002
cytochrome P450 family 3 subfamily A polypeptide 4100010
glucocorticoid receptor [Homo sapiens]150015
retinoic acid nuclear receptor alpha variant 1120012
estrogen-related nuclear receptor alpha140014
estrogen nuclear receptor alpha190019
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
IDH14004
euchromatic histone-lysine N-methyltransferase 2130013
chromobox protein homolog 16006
nuclear factor erythroid 2-related factor 2 isoform 21001
thyroid hormone receptor beta isoform 2110011
nuclear factor erythroid 2-related factor 2 isoform 18008
lethal(3)malignant brain tumor-like protein 1 isoform I1001
geminin120012
lethal factor (plasmid)5005
Polyphenol oxidase 20203
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0202
Alpha-2B adrenergic receptor0011
Spike glycoprotein5005
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, 2-oxoglutarate Oxygenase4004
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 82002
GLS protein9009
aldehyde dehydrogenase 1 family, member A17007
thyroid stimulating hormone receptor5005
hypothetical protein, conserved1001
EWS/FLI fusion protein9009
cytochrome P450 2D66006
glucocerebrosidase5005
peroxisome proliferator-activated receptor delta5005
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Bloom syndrome protein isoform 16006
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
DNA polymerase iota isoform a (long)3003
DNA polymerase kappa isoform 13003
muscarinic acetylcholine receptor M16006
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0303
Carbonic anhydrase 10608
Carbonic anhydrase 20619
Fatty acid-binding protein, liver0202
Integrin beta-32103
Myeloperoxidase0202
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10202
Integrin alpha-IIb2103
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10508
Adenosine receptor A2a05010
Substance-P receptor0303
Prostaglandin G/H synthase 20303
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma3003
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-156213
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Sigma non-opioid intracellular receptor 10516
Sigma non-opioid intracellular receptor 10112
Chain A, Cruzipain1001
SMAD family member 23003
SMAD family member 33003
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)6006
nuclear receptor subfamily 1, group I, member 39009
retinoid X nuclear receptor alpha110011
pregnane X nuclear receptor110011
peroxisome proliferator activated receptor gamma6006
caspase-32002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
Caspase-72002
vitamin D3 receptor isoform VDRA1001
thyroid hormone receptor beta isoform a4004
caspase-32002
Voltage-dependent calcium channel gamma-2 subunit6006
Solute carrier organic anion transporter family member 2B1 0001
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
Cellular tumor antigen p537007
ATP-dependent translocase ABCB108219
Insulin receptor 0101
Glutamate receptor 26006
Dipeptidyl peptidase 40101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
Histone deacetylase 10202
Histone deacetylase 20202
Solute carrier organic anion transporter family member 1B30203
Histone deacetylase 60202
Broad substrate specificity ATP-binding cassette transporter ABCG20516
Solute carrier organic anion transporter family member 1B10506
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain3003
Luciferase3003
glp-1 receptor, partial5005
BRCA12002
phosphopantetheinyl transferase5005
hypoxia-inducible factor 1 alpha subunit1001
ATAD5 protein, partial4004
PPM1D protein2002
TDP1 protein100010
STAT3, partial0011
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
progesterone receptor5005
farnesoid X nuclear receptor5005
P532002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
aryl hydrocarbon receptor5005
activating transcription factor 66006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
v-jun sarcoma virus 17 oncogene homolog (avian)4004
cytochrome P450 2D6 isoform 12002
NPC intracellular cholesterol transporter 1 precursor2002
cellular tumor antigen p53 isoform a2002
polyunsaturated fatty acid lipoxygenase ALOX121001
cytochrome P450 2C19 precursor2002
cytochrome P450 2C9 precursor2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
histone deacetylase 9 isoform 32002
mitogen-activated protein kinase 13003
nuclear factor NF-kappa-B p105 subunit isoform 10011
ras-related protein Rab-9A3003
signal transducer and activator of transcription 1-alpha/beta isoform alpha0011
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
nuclear receptor ROR-gamma isoform 13003
survival motor neuron protein isoform d5005
cytochrome P450 3A4 isoform 15005
transcription factor p65 isoform 10011
Estrogen receptor beta0011
Gamma-aminobutyric acid receptor subunit pi55111
Carbonic anhydrase 120204
Aldo-keto reductase family 1 member B100101
Lysine-specific histone demethylase 1A0202
Pancreatic triacylglycerol lipase0202
Triosephosphate isomerase0202
Interferon beta6006
Glucocorticoid receptor0002
Androgen receptor0204
Aromatase0405
Aldo-keto reductase family 1 member B10202
Gamma-aminobutyric acid receptor subunit beta-155111
Carbonyl reductase [NADPH] 10202
Gamma-aminobutyric acid receptor subunit delta55111
Gamma-aminobutyric acid receptor subunit gamma-255212
Estrogen receptor0011
Gamma-aminobutyric acid receptor subunit alpha-555111
Gamma-aminobutyric acid receptor subunit alpha-355111
Amine oxidase [flavin-containing] A0404
Carbonic anhydrase 40204
Gamma-aminobutyric acid receptor subunit gamma-155111
Gamma-aminobutyric acid receptor subunit alpha-255111
Amine oxidase [flavin-containing] B0505
Gamma-aminobutyric acid receptor subunit alpha-455111
Gamma-aminobutyric acid receptor subunit gamma-355111
Gamma-aminobutyric acid receptor subunit alpha-655111
Testosterone 17-beta-dehydrogenase 30202
17-beta-hydroxysteroid dehydrogenase type 20202
Carbonic anhydrase 70204
Histamine H2 receptor3003
Gamma-aminobutyric acid receptor subunit beta-355111
Gamma-aminobutyric acid receptor subunit beta-255212
TAR DNA-binding protein 434004
GABA theta subunit55111
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)0202
ATPase family AAA domain-containing protein 54004
Ataxin-26006
Gamma-aminobutyric acid receptor subunit epsilon55111
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
thyroid stimulating hormone receptor4004
atrial natriuretic peptide receptor 1 precursor2002
DNA polymerase beta3003
Potassium channel subfamily K member 20224
Glycogen phosphorylase, muscle form0101
Renin0202
Cholinesterase0404
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0202
Adenosine receptor A30202
Replicase polyprotein 1ab0202
Acetylcholinesterase0426
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0404
Adenosine receptor A30202
Adenosine receptor A2a06311
Adenosine receptor A2b0204
Adenosine receptor A2b0305
Adenosine receptor A105211
Vasopressin V2 receptor0002
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0202
Adenosine receptor A10202
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0202
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10002
Chitotriosidase-10202
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0103
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0235
Endochitinase B10202
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Guanine deaminase0101
ATP-dependent phosphofructokinase8008
peripheral myelin protein 227007
Gamma-aminobutyric acid receptor subunit pi0606
Gamma-aminobutyric acid receptor subunit delta0606
Gamma-aminobutyric acid receptor subunit alpha-10303
Gamma-aminobutyric acid receptor subunit beta-10303
Neuronal acetylcholine receptor subunit alpha-41203
Gamma-aminobutyric acid receptor subunit alpha-20303
Gamma-aminobutyric acid receptor subunit alpha-30303
Neuronal acetylcholine receptor subunit beta-21203
Gamma-aminobutyric acid receptor subunit alpha-10639
Gamma-aminobutyric acid receptor subunit beta-10617
Gamma-aminobutyric acid receptor subunit gamma-20628
Gamma-aminobutyric acid receptor subunit alpha-40303
Gamma-aminobutyric acid receptor subunit gamma-20303
Gamma-aminobutyric acid receptor subunit beta-30628
Translocator protein0202
Translocator protein0202
Cholecystokinin receptor type A0202
Gastrin/cholecystokinin type B receptor0202
Gamma-aminobutyric acid receptor subunit alpha-50639
Gamma-aminobutyric acid receptor subunit alpha-30628
Gamma-aminobutyric acid receptor subunit alpha-20628
Gamma-aminobutyric acid receptor subunit beta-20628
Gamma-aminobutyric acid receptor subunit alpha-40617
Gamma-aminobutyric acid receptor subunit epsilon0606
Gamma-aminobutyric acid receptor subunit alpha-60617
Gamma-aminobutyric acid receptor subunit gamma-10606
Gamma-aminobutyric acid receptor subunit gamma-30606
Gamma-aminobutyric acid receptor subunit theta0606
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Amyloid-beta precursor protein0303
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20112
Muscarinic acetylcholine receptor M10202
5-hydroxytryptamine receptor 2C0202
Tryptophan 5-hydroxylase 10202
5-hydroxytryptamine receptor 2A0202
D0202
5-hydroxytryptamine receptor 1A0617
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Liver carboxylesterase 10102
Sodium-dependent noradrenaline transporter 0202
Sodium-dependent dopamine transporter0202
5-hydroxytryptamine receptor 1B0303
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60101
Sodium-dependent serotonin transporter0707
Sodium-dependent serotonin transporter0506
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Glutamate receptor ionotropic, NMDA 1 0102
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
D(2) dopamine receptor0404
Glutamate receptor ionotropic, NMDA 2A 0102
Glutamate receptor ionotropic, NMDA 2B0203
Glutamate receptor ionotropic, NMDA 2C0102
Sodium-dependent dopamine transporter 0505
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0404
Potassium voltage-gated channel subfamily H member 20707
Leukotriene B4 receptor 10101
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0102
5-hydroxytryptamine receptor 4 0101
Glutamate receptor ionotropic, NMDA 3B0102
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A0102
Transporter0303
heat shock protein beta-11001
importin subunit beta-1 isoform 12002
snurportin-12002
GTP-binding nuclear protein Ran isoform 11001
Rap guanine nucleotide exchange factor 31001
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Gamma-aminobutyric acid 0112
G5005
Voltage-dependent L-type calcium channel subunit alpha-1F0404
HLA class I histocompatibility antigen, B alpha chain 5005
Alpha-1-acid glycoprotein 10001
Albumin0034
Albumin0011
Translocator protein0124
Gamma-aminobutyric acid receptor subunit alpha-60112
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit delta0112
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit gamma-30112
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-30112
Voltage-dependent L-type calcium channel subunit alpha-1D 0404
Neuronal acetylcholine receptor subunit alpha-70202
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit pi0112
Sphingosine-1-phosphate lyase 10101
Inositol hexakisphosphate kinase 15005
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit theta0112
Gamma-aminobutyric acid receptor subunit gamma-10112
cytochrome P450 2C9, partial5005
regulator of G-protein signaling 45005
D(1A) dopamine receptor3003
huntingtin isoform 22002
histone acetyltransferase KAT2A isoform 13003
Solute carrier family 22 member 1 0606
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Cytochrome P450 3A40618
Cytochrome P450 2C9 0415
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Voltage-dependent L-type calcium channel subunit alpha-1D0202
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0202
5-hydroxytryptamine receptor 70404
Cytochrome P450 2J20202
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Potassium voltage-gated channel subfamily A member 10101
Sodium channel protein type 5 subunit alpha0404
Sodium channel protein type 9 subunit alpha0202
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
Acetylcholinesterase0303
Bile salt export pump0202
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Acetylcholinesterase0101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] A 0202
Amine oxidase [flavin-containing] A 0202
Acetylcholinesterase0101
Acetylcholinesterase 0303
Choline O-acetyltransferase 0101
Acetylcholinesterase0202
Glycogen synthase kinase-3 beta0101
Beta-secretase 10101
Cholinesterase0202
Cholinesterase0101
Acetylcholine receptor subunit epsilon0101
Cytochrome P450 1B10202
Sigma non-opioid intracellular receptor 10202
Acyl-CoA:cholesterol acyltransferase 0101
Carboxylic ester hydrolase 0202
Carboxylic ester hydrolase 0303
Histamine H3 receptor0202
arylsulfatase A4004
potassium voltage-gated channel subfamily H member 2 isoform d2002
Cytochrome P450 1A2 0202
Cytochrome P450 2D60404
D(3) dopamine receptor0202
D(1B) dopamine receptor0101
D(4) dopamine receptor0101
Inositol monophosphatase 12002
Sigma intracellular receptor 20101
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
bromodomain adjacent to zinc finger domain 2B4004
transcriptional regulator ERG isoform 32002
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
neuropeptide S receptor isoform A1001
Histone deacetylase 30101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Histone deacetylase 40101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10203
Histone deacetylase 70101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Platelet glycoprotein VI0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90101
Histone deacetylase 50101
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, Estrogen receptor 1 (alpha)0101
Chain A, Transthyretin0011
Chain A, Transthyretin0011
acid sphingomyelinase1001
15-lipoxygenase, partial2002
Thrombopoietin1001
Neuraminidase 0202
67.9K protein1001
Parkin1001
Alpha-mannosidase0101
pyruvate kinase2002
Histone H2A.x1001
hexokinase-4 isoform 12002
peripheral myelin protein 22 isoform 12002
glucokinase regulatory protein2002
glycogen synthase kinase-3 beta isoform 10011
flap endonuclease 13003
tyrosine-protein kinase Yes1001
M-phase phosphoprotein 83003
pyruvate kinase PKM isoform b1001
Maltase-glucoamylase, intestinal0202
5-hydroxytryptamine receptor 40404
Steroid hormone receptor ERR20101
Tyrosine-protein kinase ABL10101
Transthyretin0101
Estrogen receptor0213
Sex hormone-binding globulin0011
Tyrosine-protein kinase Fyn0202
Cyclin-dependent kinase 10101
Ornithine decarboxylase1001
Sialidase0101
Solute carrier family 2, facilitated glucose transporter member 10101
Tyrosinase0101
Steroid hormone receptor ERR10101
Cyclin-dependent kinase 40101
Ornithine decarboxylase0101
Polyunsaturated fatty acid lipoxygenase ALOX150202
Proto-oncogene tyrosine-protein kinase Src0101
Cystic fibrosis transmembrane conductance regulator0011
17-beta-hydroxysteroid dehydrogenase type 10101
Solute carrier family 2, facilitated glucose transporter member 40101
G2/mitotic-specific cyclin-B10101
Dipeptidyl peptidase 40101
Androgen receptor0101
Protein kinase C alpha type0101
cAMP-dependent protein kinase catalytic subunit alpha0101
G1/S-specific cyclin-D10101
Thromboxane-A synthase 0101
Cruzipain0101
DNA (cytosine-5)-methyltransferase 10101
Dipeptidyl peptidase 40101
Proteasome subunit beta type-50101
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
RAC-alpha serine/threonine-protein kinase0101
Cystic fibrosis transmembrane conductance regulator0011
Alpha-glucosidase MAL320101
Signal transducer and activator of transcription 30101
Tyrosine-protein kinase CSK0101
Tyrosine-protein kinase ABL20101
Tyrosine-protein kinase SYK0101
Dual specificity mitogen-activated protein kinase kinase 40101
Quinone oxidoreductase0001
Xanthine dehydrogenase/oxidase0202
Cytoplasmic tyrosine-protein kinase BMX0101
Death-associated protein kinase 10101
Mitogen-activated protein kinase 100101
Oxysterols receptor LXR-beta0101
Amine oxidase [flavin-containing] B0101
Xanthine dehydrogenase/oxidase0101
MO15-related protein kinase Pfmrk 0101
Aldehyde oxidase0101
Oxysterols receptor LXR-alpha0101
Mitogen-activated protein kinase 140101
Tissue alpha-L-fucosidase0101
Substance-K receptor0202
Integrase 0101
Estrogen receptor beta0213
Prenyltransferase homolog0001
Dipeptidyl peptidase 30101
DNA (cytosine-5)-methyltransferase 3-like0101
Sialidase-20101
DNA (cytosine-5)-methyltransferase 3A0101
Chain A, JmjC domain-containing histone demethylation protein 3A3003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10101
Calmodulin-10101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Nischarin0101
Heparanase0011
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0303
Intestinal-type alkaline phosphatase0202
Large neutral amino acids transporter small subunit 10303
Phospholipase A-2-activating protein0202
dopamine D1 receptor1001
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
apical membrane antigen 1, AMA11001
Plasma kallikrein0001
Tyrosine-protein kinase Lck0101
Carbonic anhydrase 30102
Carbonic anhydrase 60103
Carbonic anhydrase 5A, mitochondrial0114
Carbonic anhydrase0102
Solute carrier family 15 member 10101
Carbonic anhydrase0102
SLC16A10 protein0001
Carbonic anhydrase 90103
Carbonic anhydrase 0102
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0102
Monocarboxylate transporter 100001
Carbonic anhydrase 150102
Carbonic anhydrase 130103
Carbonic anhydrase 140103
Carbonic anhydrase 5B, mitochondrial0103
phosphoglycerate kinase1001
Chain A, Beta-lactamase1001
Potassium channel subfamily K member 30101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Multidrug and toxin extrusion protein 10202
ClpP1001
Cytochrome P450 1A10101
Cytochrome P450 1A20101
Cytochrome P450 2C11 0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Metabotropic glutamate receptor 10101
Mu-type opioid receptor0519
Nociceptin receptor0101
Alpha-1A adrenergic receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear factor erythroid 2-related factor 20001
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Opioid receptor, delta 1b 0101
Opioid receptor homologue0101
ATP-dependent translocase ABCB10202
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0213
Muscarinic acetylcholine receptor M20101
Histidine decarboxylase0011
ATP-dependent translocase ABCB10203
Proteinase-activated receptor 10112
Delta-type opioid receptor0304
Delta-type opioid receptor0315
Kappa-type opioid receptor0214
Kappa-type opioid receptor0214
Mu-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Delta-type opioid receptor0214
Kappa-type opioid receptor0303
Kappa-type opioid receptor0214
Mu-type opioid receptor0215
Nociceptin receptor0101
Mu-type opioid receptor0101
Mu-type opioid receptor0303
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
thyrotropin-releasing hormone receptor1001
lysosomal alpha-glucosidase preproprotein2002
Cholesteryl ester transfer protein0101
D-amino-acid oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Chain A, NAD-dependent deacetylase0101
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
Cytochrome P450 3A50101
NAD-dependent protein deacetylase HST20101
Fatty-acid amide hydrolase 10101
Protein mono-ADP-ribosyltransferase PARP150101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
NAD-dependent protein deacetylase 0101
Solute carrier family 22 member 10101
Solute carrier family 22 member 20102
Solute carrier organic anion transporter family member 1A40101
Solute carrier family 22 member 20101
Histidine-rich protein PFHRP-II0101
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
Solute carrier organic anion transporter family member 1A10101
Solute carrier family 22 member 10203
Cytochrome P450 2D40101
Solute carrier family 22 member 20202
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
Phosphodiesterase 0202
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
5-hydroxytryptamine receptor 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Thyroid hormone receptor beta0101
Adenosine receptor A10202
Adenosine receptor A10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Guanine nucleotide-binding protein G1001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Chain A, Carbonic anhydrase 10101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110001
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80202
Arachidonate 5-lipoxygenase-activating protein0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 20101
Cytochrome P450 2C190101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Carbonic anhydrase 130101
Carbonic anhydrase 40202
Glycoprotein0101
Catechol O-methyltransferase0101
Potassium voltage-gated channel subfamily A member 30101
Histamine H2 receptor0202
Multidrug resistance-associated protein 1 0214
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 2B0202
Chloroquine resistance transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]