Compounds > picaridin
Page last updated: 2024-09-25

picaridin

Description

picaridin: picaridin is the (R,S)-isomer; an insect repellent [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID125098
CHEMBL ID2104314
CHEBI ID143733
SCHEMBL ID135432
MeSH IDM0464174

Synonyms (77)

Synonym
AC-6795
1-methylpropyl 2-(2-hydroxyethyl)-1-piperidinecarboxylate
cutter advanced
icaridin [inn]
1-(1-methylpropoxycarbonyl)-2-(2-hydroxyethyl)piperidine
icaridina [inn-spanish]
1-methylpropyl 2-(2-hydroxyethyl)piperidine-1-carboxylate
icaridine
picaridin
bayrepel
icaridinum [inn-latin]
1-piperidinecarboxylic acid, 2-(2-hydroxyethyl)-, 1-methylpropyl ester
icaridina
kbr 3023
pikaridin
icaridine [inn-french]
propidine
hsdb 7374
NCGC00163920-01
icaridin
119515-38-7
sec-butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate
NCGC00163920-02
butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate
AKOS005145519
CHEBI:143733
NCGC00163920-03
tox21_301141
dtxsid0034227 ,
NCGC00255039-01
cas-119515-38-7
dtxcid8014227
CHEMBL2104314
saltidin
sec-butyl 2-(2-hydroxyethyl)piperidine-1- carboxylate/icaridine (icaridine)
ccris 8576
unii-n51gqx0837
2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester
n51gqx0837 ,
ec 423-210-8
icaridinum
icaridin-d3
2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methyl-d3-propyl ester
FT-0602759
icaridin [hsdb]
picaridin [mi]
hydroxyethyl isobutyl piperidine carboxylate
icaridin [mart.]
hydroxyethyl isobutyl piperidine carboxylate [inci]
icaridin [who-dd]
(rs)-sec-butyl (rs)-2-(2-hydroxyethyl)piperidine-1-carboxylate
SCHEMBL135432
lcaridin
D70300
icaridin (picaridin)
QLHULAHOXSSASE-UHFFFAOYSA-N
DS-3268
BCP21313
picaridin; kbr 3023; kbr-3023; kbr3023
HY-116144
Q418792
SY111276
mfcd01756488
DB14074
picaridin 100 microg/ml in acetonitrile
lcaridinlcaridin
CS-0064147
A854464
119515-38-7 unlabeled
1-(1-methylpropoxycarbonyl)2-(2-hydroxyethyl)piperidine
icaridina (inn-spanish)
1-piperidinecarboxylic acid, 2-(2-hydroxyethyl)-2-methylpropyl ester
sg plus repellent aroma mist
icaridin (mart.)
sec-butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate/icaridine (icaridine)
icaridinum (inn-latin)
icaridine (inn-french)

Drug Classes (2)

ClassDescription
carboxylic acidA carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
piperidines
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (2)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
AR proteinHomo sapiens (human)Potency5.49410.000221.22318,912.5098AID743036
estrogen nuclear receptor alphaHomo sapiens (human)Potency54.94100.000229.305416,493.5996AID743069
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (85)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (2.35)18.2507
2000's34 (40.00)29.6817
2010's41 (48.24)24.3611
2020's8 (9.41)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials5 (5.49%)5.53%
Reviews9 (9.89%)6.00%
Case Studies2 (2.20%)4.05%
Observational0 (0.00%)0.25%
Other75 (82.42%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
piperidines[no description available]medium915
deet[no description available]medium612benzamides;
monocarboxylic acid amide		environmental contaminant;
insect repellent;
xenobiotic
ethyl-3-(n-n-butyl-n-acetyl)aminopropionate[no description available]medium211acetamides;
ethyl ester;
tertiary carboxamide
geraniol[no description available]medium303,7-dimethylocta-2,6-dien-1-ol;
monoterpenoid;
primary alcohol		allergen;
fragrance;
plant metabolite;
volatile oil component
cellulose[no description available]medium10glycoside
menthol[no description available]medium70p-menthane monoterpenoid;
secondary alcohol		volatile oil component
terpin[no description available]medium70p-menthane monoterpenoid
beta-alanine[no description available]medium40amino acid zwitterion;
beta-amino acid		agonist;
fundamental metabolite;
human metabolite;
inhibitor;
neurotransmitter
permethrin[no description available]medium50cyclopropanecarboxylate ester;
cyclopropanes		agrochemical;
ectoparasiticide;
pyrethroid ester acaricide;
pyrethroid ester insecticide;
scabicide
acetone[no description available]medium10ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
phenyl acetate[no description available]medium10benzenes;
phenyl acetates
nonanal[no description available]medium10medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde		human metabolite;
plant metabolite
methyl jasmonate[no description available]medium10
cyclopentane[no description available]medium10cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
pyrethrins[no description available]medium40
cyhalothrin[no description available]medium10aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound		agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide
decamethrin[no description available]medium20aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organobromine compound		agrochemical;
antifeedant;
calcium channel agonist;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
pyrethroid ester insecticide
piperidine[no description available]medium10azacycloalkane;
piperidines;
saturated organic heteromonocyclic parent;
secondary amine		base;
catalyst;
human metabolite;
non-polar solvent;
plant metabolite;
protic solvent;
reagent
baohuoside i[no description available]medium10glycosyloxyflavoneanti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
plant metabolite
transfluthrin[no description available]medium10carboxylic ester;
cyclopropanes;
organochlorine compound;
organofluorine compound		pyrethroid ester insecticide
fluorobenzenes[no description available]medium10monofluorobenzenesNMR chemical shift reference compound
pirimiphos methyl[no description available]medium20aminopyrimidine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide
oxybenzone[no description available]medium20hydroxybenzophenone;
monomethoxybenzene		dermatologic drug;
environmental contaminant;
protective agent;
ultraviolet filter;
xenobiotic
1-(3-cyclohexen-1-ylcarbonyl)-2-methylpiperidine[no description available]medium40
undecan-2-one[no description available]medium10dialkyl ketone;
methyl ketone		plant metabolite;
rodenticide
ss220[no description available]medium21
bromfenacoum[no description available]medium10benzenes;
naphthalenes;
ring assembly
niclosamide[no description available]medium10benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor
lauric acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
antibacterial agent;
plant metabolite
hexamethyldisiloxane[no description available]medium10organosiloxane
foscarnet[no description available]low00carboxylic acid;
one-carbon compound;
phosphonic acids		antiviral drug;
geroprotector;
HIV-1 reverse transcriptase inhibitor;
sodium-dependent Pi-transporter inhibitor
cephalothin[no description available]low00azabicycloalkene;
beta-lactam antibiotic allergen;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiophenes		antibacterial drug;
antimicrobial agent
bromoacetate[no description available]low00carboxylic acid;
organohalogen compound
dalapon[no description available]low00carboxylic acid;
organohalogen compound
alpha-naphthylphthalamic acid[no description available]low00carboxylic acid;
dicarboxylic acid monoamide;
N-(1-naphthyl)carboxamide		herbicide
ethoxyacetic acid[no description available]low00carboxylic acid
diisopropylamine dichloroacetate[no description available]low00carboxylic acid;
organohalogen compound
2-phenoxypropanoic acid[no description available]low00aromatic ether;
carboxylic acid
mafenide acetate[no description available]low00carboxylic acid
n-butoxyacetic acid[no description available]low00carboxylic acid
cefazedone[no description available]low004-pyridones;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiadiazoles		antibacterial drug
als 8123[no description available]low00carboxylic acid;
ethanolamines;
secondary amino compound
aspartame[no description available]low00carboxylic acid;
dipeptide zwitterion;
dipeptide;
methyl ester		apoptosis inhibitor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
environmental contaminant;
micronutrient;
nutraceutical;
sweetening agent;
xenobiotic
2-(4-methoxyphenoxy)propanoic acid[no description available]low00aromatic ether;
carboxylic acid
alpha-fluoro-beta-ureidopropionic acid[no description available]low00carboxylic acid;
organohalogen compound
5-oxo-1-(2-phenylethyl)-3-pyrrolidinecarboxylic acid[no description available]low00carboxylic acid;
pyrrolidinecarboxylic acid
cefpiramide[no description available]low00carboxylic acid;
cephalosporin		antibacterial drug
4-(2-benzamidoethylamino)-1-piperidinecarboxylic acid ethyl ester[no description available]low00carboxylic acid;
piperidines
1-(4,6-dimethyl-2-pyrimidinyl)-4-piperidinecarboxylic acid[no description available]low00carboxylic acid;
piperidines
1-(1-oxo-2-thiophen-2-ylethyl)-4-piperidinecarboxylic acid ethyl ester[no description available]low00carboxylic acid;
piperidines
1-(3-phenylpropanoyl)-4-piperidinecarboxylic acid[no description available]low00carboxylic acid;
piperidines
1-[2-hydroxy-3-[4-(2-methylbutan-2-yl)phenoxy]propyl]-4-piperidinecarboxylic acid ethyl ester[no description available]low00carboxylic acid;
piperidines
1-[2-[(4-chlorophenyl)thio]-1-oxopropyl]-4-piperidinecarboxylic acid ethyl ester[no description available]low00carboxylic acid;
piperidines
1-[2-[3-(N-ethylanilino)propylamino]-3,4-dioxo-1-cyclobutenyl]-4-piperidinecarboxylic acid ethyl ester[no description available]low00carboxylic acid;
piperidines
4-[[2-(3-ethylanilino)-3,4-dioxo-1-cyclobutenyl]amino]-1-piperidinecarboxylic acid ethyl ester[no description available]low00carboxylic acid;
piperidines
1-[(6-hydroxy-2-methyl-5-thiazolo[3,2-b][1,2,4]triazolyl)-(3,4,5-trimethoxyphenyl)methyl]-4-piperidinecarboxylic acid methyl ester[no description available]low00carboxylic acid;
piperidines
rifamycin b[no description available]low00acetate ester;
carboxylic acid;
organic heterotetracyclic compound;
rifamycins
pradimicin a[no description available]low00aromatic ether;
carboxylic acid;
disaccharide derivative;
L-alanine derivative;
p-quinones;
polyphenol;
pradimicin;
secondary alcohol
cefpodoxime[no description available]low00carboxylic acid;
cephalosporin		antibacterial drug
cefatrizine[no description available]low00amino acid amide;
carboxylic acid;
cephalosporin;
phenols;
semisynthetic derivative;
triazoles		antibacterial drug;
EC 2.7.11.20 (elongation factor 2 kinase) inhibitor
s 1006[no description available]low001,3-thiazoles;
carbamate ester;
carboxylic acid;
cephalosporin;
enamide;
secondary carboxamide		antibacterial drug
cinalukast[no description available]low001,3-thiazoles;
carboxylic acid		anti-arrhythmia drug;
anti-asthmatic drug;
leukotriene antagonist
cefpodoxime proxetil[no description available]low00carboxylic acid;
carboxylic ester;
cephalosporin		antibacterial drug;
prodrug
u 62840[no description available]low00carbotricyclic compound;
carboxylic acid		antihypertensive agent;
cardiovascular drug;
human blood serum metabolite;
platelet aggregation inhibitor;
vasodilator agent;
vitamin K antagonist
cefditoren[no description available]low00carboxylic acid;
cephalosporin		antibacterial drug
tubulysin a[no description available]low00carboxylic acid;
diester
tubulysin d[no description available]low00carboxylic acid;
diester
4-[[3-(4-chlorophenyl)-5-isoxazolyl]methyl]-1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinecarboxylic acid[no description available]low00carboxylic acid;
piperidines
ethyl 1-benzyl-3-hydroxy-2(5h)-oxopyrrole-4-carboxylate[no description available]low00carboxylic acid;
pyrroline
cefiderocol[no description available]low00carboxylic acid;
cephalosporin		antibacterial drug;
siderophore
astemizole[no description available]low00benzimidazoles;
piperidines		anti-allergic agent;
anticoronaviral agent;
H1-receptor antagonist
biperiden[no description available]low00piperidines;
tertiary alcohol;
tertiary amino compound		antidote to sarin poisoning;
antidyskinesia agent;
antiparkinson drug;
muscarinic antagonist;
parasympatholytic
clebopride[no description available]low00piperidines
cycrimine[no description available]low00piperidines;
tertiary alcohol;
tertiary amino compound		antidyskinesia agent;
antiparkinson drug;
muscarinic antagonist
cyproheptadine[no description available]low00piperidines;
tertiary amine		anti-allergic agent;
antipruritic drug;
gastrointestinal drug;
H1-receptor antagonist;
serotonergic antagonist
diphenidol[no description available]low00benzenes;
piperidines;
tertiary alcohol		antiemetic
diphenylpyraline[no description available]low00piperidines;
tertiary amine		cholinergic antagonist;
H1-receptor antagonist
dipyridamole[no description available]low00piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
donepezil[no description available]low00aromatic ether;
indanones;
piperidines;
racemate		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nootropic agent
dyclonine[no description available]low00aromatic ketone;
piperidines		topical anaesthetic
eperisone[no description available]low00aromatic ketone;
piperidines
ethyl piperidinoacetylaminobenzoate[no description available]low00benzoate ester;
piperidines
fentanyl[no description available]low00anilide;
monocarboxylic acid amide;
piperidines		adjuvant;
anaesthesia adjuvant;
anaesthetic;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic
fexofenadine[no description available]low00piperidines;
tertiary amine		anti-allergic agent;
H1-receptor antagonist
flavoxate[no description available]low00carboxylic ester;
flavones;
piperidines;
tertiary amino compound		antispasmodic drug;
muscarinic antagonist;
parasympatholytic
flecainide[no description available]low00aromatic ether;
monocarboxylic acid amide;
organofluorine compound;
piperidines		anti-arrhythmia drug
glutethimide[no description available]low00piperidines
ifenprodil[no description available]low00piperidines
ketanserin[no description available]low00aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
ketotifen[no description available]low00cyclic ketone;
olefinic compound;
organic heterotricyclic compound;
organosulfur heterocyclic compound;
piperidines;
tertiary amino compound		anti-asthmatic drug;
H1-receptor antagonist
loperamide[no description available]low00monocarboxylic acid amide;
monochlorobenzenes;
piperidines;
tertiary alcohol		anticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
mazaticol[no description available]low00piperidines
mefloquine hydrochloride[no description available]low00organofluorine compound;
piperidines;
quinolines;
secondary alcohol
methylphenidate[no description available]low00beta-amino acid ester;
methyl ester;
piperidines
methixene[no description available]low00piperidines;
thioxanthenes		antiparkinson drug;
histamine antagonist;
muscarinic antagonist
perhexiline[no description available]low00piperidinescardiovascular drug
pridinol[no description available]low00piperidines;
tertiary alcohol		antiparkinson drug;
muscle relaxant
ritanserin[no description available]low00organofluorine compound;
piperidines;
thiazolopyrimidine		antidepressant;
antipsychotic agent;
anxiolytic drug;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
roxatidine acetate[no description available]low00piperidines
sb 220025[no description available]low00aminopyrimidine;
imidazoles;
organofluorine compound;
piperidines		angiogenesis inhibitor;
anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
spiperone[no description available]low00aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist
thioridazine[no description available]low00phenothiazines;
piperidines		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
tipepidine[no description available]low00piperidines
vesamicol[no description available]low00piperidines
diphemanil methylsulfate[no description available]low00piperidines;
quaternary ammonium salt		bronchodilator agent;
muscarinic antagonist;
parasympatholytic
phencyclidine[no description available]low00benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
pempidine[no description available]low00piperidines
2-hydroxy-2-phenylacetic acid (1,2,2,6-tetramethyl-4-piperidinyl) ester[no description available]low00piperidines
2-methylpiperidine[no description available]low00piperidines
jervine[no description available]low00piperidines
ketobemidone[no description available]low00piperidines
phenoperidine[no description available]low00piperidines
benzetimide[no description available]low00piperidines
piminodine[no description available]low00piperidines
dexetimide[no description available]low00piperidines
4-(4-chlorophenyl)-4-hydroxypiperidine[no description available]low00piperidines
sufentanil[no description available]low00anilide;
ether;
piperidines;
thiophenes		anaesthesia adjuvant;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic
paroxetine[no description available]low00aromatic ether;
benzodioxoles;
organofluorine compound;
piperidines		antidepressant;
anxiolytic drug;
hepatotoxic agent;
P450 inhibitor;
serotonin uptake inhibitor
encainide[no description available]low00benzamides;
piperidines		anti-arrhythmia drug;
sodium channel blocker
alfentanil[no description available]low00monocarboxylic acid amide;
piperidines		central nervous system depressant;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic;
peripheral nervous system drug
miglustat[no description available]low00piperidines;
tertiary amino compound		anti-HIV agent;
EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor
levocabastine[no description available]low00piperidines
preclamol[no description available]low00piperidines
loxtidine[no description available]low00aromatic ether;
piperidines;
primary alcohol;
triazoles		H2-receptor antagonist
tzu 0460[no description available]low00piperidines
eliprodil[no description available]low00monochlorobenzenes;
monofluorobenzenes;
piperidines;
secondary alcohol;
tertiary amino compound
tirofiban[no description available]low00L-tyrosine derivative;
piperidines;
sulfonamide		anticoagulant;
fibrin modulating drug;
platelet glycoprotein-IIb/IIIa receptor antagonist
3-methylfentanyl[no description available]low00monocarboxylic acid amide;
piperidines		mu-opioid receptor agonist;
opioid analgesic;
sedative
carfentanil[no description available]low00methyl ester;
piperidines;
tertiary amino compound;
tertiary carboxamide		mu-opioid receptor agonist;
opioid analgesic;
tranquilizing drug
f 7302[no description available]low00piperidines
4-fluorofentanyl[no description available]low00monocarboxylic acid amide;
organofluorine compound;
piperidines
tenocyclidine[no description available]low00piperidines;
tertiary amino compound;
thiophenes		central nervous system stimulant;
hallucinogen;
neuroprotective agent;
NMDA receptor antagonist
terikalant[no description available]low00piperidines
repaglinide[no description available]low00piperidines
spiramide[no description available]low00aromatic ether;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		dopaminergic antagonist;
serotonergic antagonist
hp 873[no description available]low001,2-benzoxazoles;
aromatic ether;
aromatic ketone;
methyl ketone;
monoamine;
organofluorine compound;
piperidines;
tertiary amino compound		dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist
sufotidine[no description available]low00piperidines
fagomine[no description available]low00piperidines
1-(4-nitrophenyl)piperidine[no description available]low00piperidines
fentanyl isothiocyanate[no description available]low00piperidines
ritalinic acid[no description available]low00monocarboxylic acid;
piperidines		drug metabolite;
marine xenobiotic metabolite
fenpropidine[no description available]low00piperidines;
tertiary amine
sk&f 95282[no description available]low00piperidines
biperiden hydrochloride[no description available]low00hydrochloride;
piperidines;
tertiary alcohol		antiparkinson drug;
muscarinic antagonist;
parasympatholytic
phenglutarimide[no description available]low00piperidines
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol[no description available]low00piperidines
gr 113808[no description available]low00indolyl carboxylate ester;
piperidines;
sulfonamide		serotonergic antagonist
alphaprodine[no description available]low00piperidines
lofentanil[no description available]low00methyl ester;
piperidines;
tertiary amino compound;
tertiary carboxamide		mu-opioid receptor agonist;
opioid analgesic
1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine[no description available]low001-benzothiophenes;
piperidines;
tertiary amino compound		dopamine uptake inhibitor
5-(4-piperidyl)isoxazol-3-ol[no description available]low00piperidines
ku 1257[no description available]low00piperidines
l 733060[no description available]low00piperidines
n-(n-benzylpiperidin-4-yl)-4-iodobenzamide[no description available]low00piperidines
l 741626[no description available]low00piperidines
aminopotentidine[no description available]low00aromatic ether;
benzamides;
guanidines;
nitrile;
piperidines;
substituted aniline		H2-receptor antagonist
migalastat[no description available]low00piperidines
zanapezil[no description available]low00piperidines
anacoline iodide[no description available]low00dioxolane;
piperidines
norfentanyl[no description available]low00anilide;
monocarboxylic acid amide;
piperidines		drug metabolite;
opioid analgesic
miglitol[no description available]low00piperidines
magellanine[no description available]low00piperidines
tecomine[no description available]low00piperidines
cyclopamine[no description available]low00piperidinesglioma-associated oncogene inhibitor
isofagomine[no description available]low00piperidines
efinaconazole[no description available]low00conazole antifungal drug;
olefinic compound;
organofluorine compound;
piperidines;
tertiary alcohol;
tertiary amino compound;
triazole antifungal drug		EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
N-(1,3-benzodioxol-5-yl)-1-[4-(4-morpholinylsulfonyl)phenyl]-4-piperidinecarboxamide[no description available]low00piperidines
N-(1-adamantyl)-4-(1,3-benzodioxol-5-yl)-4-hydroxy-1-piperidinecarboxamide[no description available]low00piperidines
2-[(1,3-dimethyl-2,6-dioxo-7-propyl-8-purinyl)thio]-N-[2-(1-piperidinyl)phenyl]acetamide[no description available]low00piperidines
4-methyl-N-[3-[1-(phenylmethyl)-4-piperidinyl]-2,4-dihydro-1H-1,3,5-triazin-6-yl]benzenesulfonamide[no description available]low00piperidines
N-[3-(dimethylamino)-2,2-dimethylpropyl]-1-[(2-hydroxyphenyl)methyl]-4-piperidinecarboxamide[no description available]low00piperidines
N-(2-ethoxyphenyl)-1-[4-(1-pyrrolidinylsulfonyl)phenyl]-4-piperidinecarboxamide[no description available]low00piperidines
N-(4-{[2-(pyridin-3-yl)piperidin-1-yl]sulfonyl}phenyl)acetamide[no description available]low00acetamides;
piperidines;
pyridines;
sulfonamide
4-Piperidinobenzoic acid[no description available]low00piperidines
N-methyl-2-(4-methylphenyl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine[no description available]low00piperidines;
quinazolines;
tertiary amino compound;
toluenes
2-(2-methylphenoxy)-N-[2-(4-methyl-1-piperidinyl)phenyl]acetamide[no description available]low00piperidines
2-(phenylmethyl)-5-[4-(phenylmethyl)-1-piperidinyl]-4-oxazolecarbonitrile[no description available]low00piperidines
1-(phenylmethyl)-N'-(2,4,6-trimethylphenyl)sulfonyl-4-piperidinecarbohydrazide[no description available]low00piperidines
1-[2-[(4-methyl-2-oxo-1-benzopyran-7-yl)oxy]-1-oxoethyl]-4-phenyl-4-piperidinecarboxylic acid[no description available]low00piperidines
3-[2-oxo-2-[4-(phenylmethyl)-1-piperidinyl]ethyl]-1,3-diazaspiro[4.6]undecane-2,4-dione[no description available]low00piperidines
1-[1-(phenylmethyl)-4-piperidinyl]-3-(2,4,4-trimethylpentan-2-yl)thiourea[no description available]low00piperidines
4-[4-(phenylmethyl)-1-piperidinyl]thieno[2,3-d]pyrimidine[no description available]low00piperidines;
thienopyrimidine
cyclohexanecarboxylic acid [2-oxo-2-[4-(1-piperidinyl)anilino]ethyl] ester[no description available]low00piperidines
1-[1-(phenylmethyl)-4-piperidinyl]-3-(2-propan-2-ylphenyl)thiourea[no description available]low00piperidines
1-(4-ethylphenyl)-3-[1-(phenylmethyl)-4-piperidinyl]thiourea[no description available]low00piperidines
tempo[no description available]low00aminoxyls;
piperidines		catalyst;
ferroptosis inhibitor;
radical scavenger
4-maleimido-2,2,6,6-tetramethylpiperidinooxyl[no description available]low00aminoxyls;
dicarboximide;
maleimides;
piperidines		radical scavenger;
spin label
N-(4-bromophenyl)-4-(2-methoxyphenyl)-1-piperidinecarbothioamide[no description available]low00piperidines
N1-(1-benzyl-4-piperidyl)-4-chlorobenzene-1-sulfonamide[no description available]low00piperidines
3,3-dimethyl-1-[4-(trifluoromethoxy)phenyl]piperidine-2,6-dione[no description available]low00piperidines
1-[(3,5-dimethylisoxazol-4-yl)sulfonyl]piperidine[no description available]low00piperidines
4-(benzenesulfonyl)-1-[(4-chlorophenyl)methyl]-4-piperidinecarboxylic acid ethyl ester[no description available]low00piperidines
2-benzyl-6-hydroxy-2-azabicyclo[2.2.2]octan-3-one[no description available]low00piperidines
5-methyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-thieno[2,3-d]pyrimidinamine[no description available]low00piperidines;
thienopyrimidine
N-[1-(2-chloro-6-fluorobenzyl)-4-piperidinyl]-N'-(4-fluorophenyl)urea[no description available]low00piperidines
[4-(2-methoxyphenyl)-1-piperidinyl]-(5-methyl-1-phenyl-4-pyrazolyl)methanone[no description available]low00piperidines
4-acetamidobenzenesulfonic acid [2-(1-piperidinyl)phenyl] ester[no description available]low00piperidines
4-fluoro-N-[2-(1-piperidinyl)phenyl]benzenesulfonamide[no description available]low00piperidines
1-(2-fluorophenyl)-3-[2-(1-piperidinyl)phenyl]urea[no description available]low00piperidines
4-(1-piperidinyl)-3-[[3-(trifluoromethyl)phenyl]sulfonylamino]benzoic acid ethyl ester[no description available]low00piperidines
1-[(3-chlorophenyl)methyl]-N,N-diethyl-3-piperidinecarboxamide[no description available]low00piperidines
3-hydroxy-5-nitro-2-phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-triazolimine[no description available]low00piperidines
1-(3-chlorophenyl)-3-[[1-[(2,5-dimethoxyphenyl)methyl]-4-piperidinyl]methyl]urea[no description available]low00piperidines
femoxetine[no description available]low00piperidines
4-phenyl-1-(4-phenylbutyl)piperidine[no description available]low00piperidines
4-(1h-imidazol-4-ylmethyl)piperidine[no description available]low00piperidines
tandutinib[no description available]low00aromatic ether;
N-arylpiperazine;
N-carbamoylpiperazine;
phenylureas;
piperidines;
quinazolines;
tertiary amino compound		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
zd 6474[no description available]low00aromatic ether;
organobromine compound;
organofluorine compound;
piperidines;
quinazolines;
secondary amine		antineoplastic agent;
tyrosine kinase inhibitor
6-phenylspiro[7-oxa-1-azabicyclo[2.2.1]heptane-2,1'-cyclopentane][no description available]low00piperidines
3,5-dimethyl-2,6-bis(4-methylphenyl)-4-piperidinone[no description available]low00piperidines
1-[9-[(4-fluorophenyl)methyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-(2-phenylphenyl)urea[no description available]low00piperidines
4-(2-fluorophenyl)-1-[[1-[(4-methoxyphenyl)methyl]-5-tetrazolyl]methyl]-4-piperidinol[no description available]low00piperidines
1-(3-methylphenyl)-3-[[1-[4-(4-morpholinylsulfonyl)phenyl]-4-piperidinyl]methyl]urea[no description available]low00piperidines
1-(2-methylphenyl)-3-[[1-[4-(4-morpholinylsulfonyl)phenyl]-4-piperidinyl]methyl]urea[no description available]low00piperidines
N-[2-(3,4-dimethoxyphenyl)ethyl]-1-[(3,4-dimethoxyphenyl)methyl]-N-methyl-3-piperidinecarboxamide[no description available]low00piperidines
1,4-dimethyl-6-[[4-(phenylmethyl)-1-piperidinyl]sulfonyl]quinoxaline-2,3-dione[no description available]low00piperidines
1-[(3-chlorophenyl)methyl]-N-methyl-N-(phenylmethyl)-3-piperidinecarboxamide[no description available]low00piperidines
4-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitrobenzoic acid methyl ester[no description available]low00piperidines
benzoic acid [[1-(4-nitrophenyl)-4-piperidinylidene]amino] ester[no description available]low00piperidines
1-[(4-chlorophenyl)methyl]-4-(4-chlorophenyl)sulfonyl-4-piperidinecarboxylic acid ethyl ester[no description available]low00piperidines
1-[3-[(2-methoxyphenyl)sulfamoyl]-4-(1-piperidinyl)phenyl]-3-(3-methylphenyl)urea[no description available]low00piperidines
1-pyrrolidinyl-[1-[(2,3,4-trimethoxyphenyl)methyl]-3-piperidinyl]methanone[no description available]low00piperidines
2-[1-[4-(diethylamino)phenyl]-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-N-phenylacetamide[no description available]low00piperidines
2-(hexylamino)-1-[4-(phenylmethyl)-1-piperidinyl]ethanone[no description available]low00piperidines
LY-310762[no description available]low00aromatic ketone;
monofluorobenzenes;
oxindoles;
piperidines;
tertiary amino compound		receptor modulator;
serotonergic antagonist
5-(4-morpholinylsulfonyl)-2-(1-piperidinyl)benzoic acid [2-[[(3-methylbutylamino)-oxomethyl]amino]-2-oxoethyl] ester[no description available]low00piperidines
2-methyl-2,6-diphenyl-7-oxa-1-azabicyclo[2.2.1]heptane[no description available]low00piperidines
N-(3-isoxazolyl)-3-nitro-4-(1-piperidinyl)benzamide[no description available]low00piperidines
N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-4-(4-methyl-1-piperidinyl)-3-nitrobenzamide[no description available]low00piperidines
2-phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine[no description available]low00piperidines
N-(1-benzylpiperidin-4-yl)-2-(pyridin-3-yl)quinazolin-4-amine[no description available]low00aromatic amine;
piperidines;
pyridines;
quinazolines;
secondary amino compound;
tertiary amino compound
1-(4-carbamoyl-2-nitrophenyl)-4-piperidinecarboxylic acid methyl ester[no description available]low00piperidines
N-(1,3-benzodioxol-5-yl)-4-(4-methyl-1-piperidinyl)-3-nitrobenzamide[no description available]low00piperidines
5-[2-furanyl-[4-(phenylmethyl)-1-piperidinyl]methyl]-6-thiazolo[3,2-b][1,2,4]triazolol[no description available]low00piperidines
5-nitro-6-(3-nitrophenyl)-2-piperidinone[no description available]low00piperidines
3-nitro-4-[2-[1-(phenylmethyl)-4-piperidinylidene]hydrazinyl]benzenesulfonamide[no description available]low00piperidines
pibutidine[no description available]low00aromatic ether;
cyclobutenones;
olefinic compound;
piperidines;
primary amino compound;
pyridines;
secondary amino compound		anti-ulcer drug;
H2-receptor antagonist
N-[4-[(4-methyl-1-piperidinyl)methyl]phenyl]-1-[5-(1-pyrrolyl)-1,3,4-thiadiazol-2-yl]-4-piperidinecarboxamide[no description available]low00piperidines
palbociclib[no description available]low00aminopyridine;
aromatic ketone;
cyclopentanes;
piperidines;
pyridopyrimidine;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
1-(2-chlorophenyl)-3-[4-(1-piperidinylmethyl)phenyl]urea[no description available]low00piperidines
opc-67683[no description available]low00piperidines
ro 25-6981[no description available]low00benzenes;
phenols;
piperidines;
secondary alcohol;
tertiary amino compound		anticonvulsant;
antidepressant;
neuroprotective agent;
NMDA receptor antagonist
pd 174494[no description available]low00piperidines
2-ethoxy-N-[1-(phenylmethyl)-4-piperidinyl]benzamide[no description available]low00piperidines
n-demethylloperamide[no description available]low00monocarboxylic acid amide;
monochlorobenzenes;
piperidines;
tertiary alcohol		drug metabolite
bms201038[no description available]low00(trifluoromethyl)benzenes;
benzamides;
fluorenes;
piperidines		anticholesteremic drug;
MTP inhibitor
casopitant[no description available]low00piperidines
pimavanserin[no description available]low00aromatic ether;
monofluorobenzenes;
piperidines;
tertiary amino compound;
ureas		5-hydroxytryptamine 2A receptor inverse agonist;
antipsychotic agent;
serotonergic antagonist
rolapitant[no description available]low00azaspiro compound;
ether;
organofluorine compound;
piperidines;
pyrrolidin-2-ones		antiemetic;
neurokinin-1 receptor antagonist
at 7867[no description available]low00monochlorobenzenes;
piperidines;
pyrazoles		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
at 7519[no description available]low00dichlorobenzene;
piperidines;
pyrazoles;
secondary carboxamide		antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
alogliptin[no description available]low00nitrile;
piperidines;
primary amino compound;
pyrimidines		EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
hypoglycemic agent
azd 8931[no description available]low00aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
quinazolines;
secondary amino compound;
tertiary amino compound		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist
pf 00299804[no description available]low00enamide;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist
dorsomorphin[no description available]low00aromatic ether;
piperidines;
pyrazolopyrimidine;
pyridines		bone morphogenetic protein receptor antagonist;
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor
6-o-desmethyl donepezil[no description available]low00piperidines
nvp-tae684[no description available]low00piperidines
[3-[(2-methylphenyl)methyl]-1-[(5-methyl-2-thiophenyl)methyl]-3-piperidinyl]methanol[no description available]low00piperidines
2-(2-fluoro-5-methoxyphenyl)-5-methyl-4-[(4-phenyl-1-piperidinyl)methyl]oxazole[no description available]low00piperidines
[3-[(3-chlorophenyl)methyl]-1-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-3-piperidinyl]methanol[no description available]low00piperidines
2-[4-[1-(2-fluorophenyl)-4-piperidinyl]-1-[(3-methoxyphenyl)methyl]-2-piperazinyl]ethanol[no description available]low00piperidines
[1-[(1,2-dimethyl-3-indolyl)methyl]-4-[[3-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methanol[no description available]low00piperidines
[1-(2-benzofuranylmethyl)-4-[[3-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methanol[no description available]low00piperidines
1-(5-isoquinolinylmethyl)-4-[(3-methoxyphenyl)methyl]-4-piperidinecarboxylic acid ethyl ester[no description available]low00piperidines
3-[[4-[(4-chlorophenyl)methyl]-4-(hydroxymethyl)-1-piperidinyl]-oxomethyl]-4,5-dihydro-1H-pyridazin-6-one[no description available]low00piperidines
1-(2-chloro-4-methylphenyl)-3-[[1-[(3-chlorophenyl)methyl]-4-piperidinyl]methyl]urea[no description available]low00piperidines
1-(12-oxo-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-2-yl)-3-[3-[4-(phenylmethyl)-1-piperidinyl]propyl]thiourea[no description available]low00piperidines
3-hydroxy-2-(3-methylphenyl)-5-nitro-N-[1-(phenylmethyl)-4-piperidinyl]-4-triazolimine[no description available]low00piperidines
4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-[[3-(trifluoromethyl)phenyl]methyl]piperidine[no description available]low00piperidines
gdc-0973[no description available]low00aromatic amine;
difluorobenzene;
N-acylazetidine;
organoiodine compound;
piperidines;
secondary amino compound;
tertiary alcohol		antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
gsk690693[no description available]low001,2,5-oxadiazole;
acetylenic compound;
aromatic amine;
aromatic ether;
imidazopyridine;
piperidines;
primary amino compound;
tertiary alcohol		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
WAY-316606[no description available]low00(trifluoromethyl)benzenes;
piperidines;
secondary amino compound;
sulfonamide;
sulfone		secreted frizzled-related protein 1 inhibitor
N-butyl-4-(phenylmethyl)-1-piperidinecarbothioamide[no description available]low00piperidines
alcaftadine[no description available]low00aldehyde;
imidazobenzazepine;
piperidines;
tertiary amino compound		anti-allergic agent;
H1-receptor antagonist
N-(2-methylpropyl)-4-(phenylmethyl)-1-piperidinecarbothioamide[no description available]low00piperidines
4-(phenylmethyl)-N-prop-2-enyl-1-piperidinecarbothioamide[no description available]low00piperidines
N-[2-[1-[(4-methoxy-3-methylphenyl)methyl]-4-piperidinyl]-3-pyrazolyl]-4-phenylbutanamide[no description available]low00piperidines
2-(2,6-dimethylphenoxy)-N-[2-(1-piperidinyl)phenyl]acetamide[no description available]low00piperidines
niraparib[no description available]low00benzenes;
indazoles;
piperidines;
primary carboxamide		antineoplastic agent;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
ipi-926[no description available]low00piperidines
asp3026[no description available]low00aromatic amine;
diamino-1,3,5-triazine;
monomethoxybenzene;
N-methylpiperazine;
piperidines;
secondary amino compound;
sulfone		antimalarial;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 6.1.1.6 (lysine--tRNA ligase) inhibitor
bix 01294[no description available]low00piperidines
pf 3845[no description available]low00piperidines
glasdegib[no description available]low00benzimidazoles;
nitrile;
phenylureas;
piperidines		antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist
1-[3-methoxy-4-[[4-(2-propan-2-ylsulfonylanilino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol[no description available]low00piperidines
1-[4-[[4-amino-5-chloro-6-(2-propan-2-ylsulfonylanilino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-piperidinecarboxamide[no description available]low00piperidines
2,3-dimethoxy-N-[4-(1-piperidinyl)phenyl]aniline[no description available]low00piperidines
ulixacaltamide[no description available]low00benzamides;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
secondary carboxamide		non-narcotic analgesic;
T-type calcium channel blocker
Mps1-IN-2[no description available]low00piperidines
gilteritinib[no description available]low00aromatic amine;
monomethoxybenzene;
N-methylpiperazine;
oxanes;
piperidines;
primary carboxamide;
pyrazines;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
alectinib[no description available]low00aromatic ketone;
morpholines;
nitrile;
organic heterotetracyclic compound;
piperidines		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
ceritinib[no description available]low00aminopyrimidine;
aromatic ether;
organochlorine compound;
piperidines;
secondary amino compound;
sulfone		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
gsk2879552[no description available]low00benzenes;
benzoic acids;
cyclopropanes;
monocarboxylic acid;
piperidines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor
ldc4297[no description available]low00aromatic ether;
piperidines;
pyrazoles;
pyrazolotriazine;
secondary amino compound		antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
PF-06446846[no description available]low00benzamides;
monochloropyridine;
piperidines;
tertiary carboxamide;
triazolopyridine		antilipemic drug;
EC 3.4.21.61 (kexin) inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
Adverse Drug Event0low10
Adverse Drug Reaction0low10
Allergic Contact Dermatitis0low10
American Trypanosomiasis0low10
Arbovirus Infections0low10
Bilateral Headache0medium11
Bites0low20
Bites and Stings0low20
Black Fever0low10
Body Weight0low30
Cephalalgia0medium11
Cephalgia0medium11
Cephalodynia0medium11
Chagas Disease0low10
Chagas' Disease0low10
Congenital Zika Syndrome0low30
Congenital Zika Virus Infection0low30
Cranial Pain0medium11
Dermatitis0low10
Dermatitis, Allergic Contact0low10
Dermatitis, Allergic Eczematous0low10
Dermatitis, Contact, Allergic0low10
Dizziness0medium11
Dizzyness0medium11
Drug Side Effects0low10
Drug Toxicity0low10
Drug-Related Side Effects and Adverse Reactions0low10
Encephalitis, West Nile Fever0low10
Fasciolopsiasis0low10
Fever, Zika0low30
Generalized Headache0medium11
Head Pain0medium11
Headache0medium11
Hemicrania0medium11
Hives0low10
Infections, Plasmodium0medium51
Infections, Tick-Borne0low10
Infections, Trematode0low10
Insect Bites0low140
Insect Bites and Stings0low140
Insect Stings0low140
Kala-Azar0low10
Leishmaniasis, Visceral0low10
Light-Headedness0medium11
Lightheadedness0medium11
Malaria0medium51
Malaria, Falciparum0medium11
Malaria, Vivax0medium11
Marsh Fever0medium51
Metagonimiasis0low10
Ocular Headache0medium11
Orthostasis0medium11
Orthostatic Headache0medium11
Paludism0medium51
Periorbital Headache0medium11
Plasmodium falciparum Malaria0medium11
Plasmodium Infections0medium51
Plasmodium vivax Malaria0medium11
Pregnancy0low20
Remittent Fever0medium51
Retro-Ocular Headache0medium11
Rodent Diseases0low10
Sharp Headache0medium11
Side Effects of Drugs0low10
Stings0low20
Stings and Bites0low20
Throbbing Headache0medium11
Tick Bites0low10
Tick Borne Disease0low10
Tick Infestations0low10
Tick-Borne Diseases0low10
Tick-Borne Infection0low10
Tick-Borne Infections0low10
Toxicity, Drug0low10
Travel Sickness0low10
Travel-Associated Infections0low10
Travel-Associated Infectious Diseases0low10
Travel-Related Disease0low10
Travel-Related Health Problems0low10
Travel-Related Illness0low10
Travel-Related Infections0low10
Travel-Related Infectious Diseases0low10
Travel-Related Sickness0low10
Trematode Infections0low10
Trypanosoma cruzi Infection0low10
Trypanosomiasis, South American0low10
Unilateral Headache0medium11
Urticaria0low10
Vertex Headache0medium11
West Nile Fever0low10
West Nile Fever Encephalitis0low10
West Nile Fever Meningitis0low10
West Nile Fever Meningoencephalitis0low10
West Nile Fever Myelitis0low10
West Nile Virus Infection0low10
WNV Infection0low10
Zika Fever0low30
Zika Virus Disease0low30
Zika Virus Infection0low30
ZikV Infection0low30

Research Highlights

Safety/Toxicity (5)

ArticleYear
Use of 2D and co-culture cell models to assess the toxicity of zein nanoparticles loading insect repellents icaridin and geraniol.
Colloids and surfaces. B, Biointerfaces, Volume: 216		2022
Safety of a topical insect repellent (picaridin) during community mass use for malaria control in rural Cambodia.
PloS one, Volume: 12, Issue: 3		2017
The toxicity of picaridin containing insect repellent reported to the National Poison Data System.
Clinical toxicology (Philadelphia, Pa.), Volume: 54, Issue: 8		2016
Conduct and interpretation of a dermal developmental toxicity study with KBR 3023 (a prospective insect repellent) in the Sprague-Dawley rat and Himalayan rabbit.
Teratology, Volume: 61, Issue: 3		2000
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Comparative Pharmacokinetics Study of Icariin and Icariside II in Rats.
Molecules (Basel, Switzerland), Dec-01, Volume: 20, Issue: 12		2015
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (9)

ArticleYear
Mosquito repellents for the traveller: does picaridin provide longer protection than DEET?
Journal of travel medicine, May-01, Volume: 25, Issue: suppl_1		2018
Evaluation of Clove Oil, Icaridin, and Transfluthrin for Spatial Repellent Effects in Three Tests Systems Against the Aedes aegypti (Diptera: Culicidae).
Journal of medical entomology, Volume: 54, Issue: 1		2017
Solvent, drying time, and substrate affect the responses of lone star ticks (Acari: Ixodidae) to the repellents deet and picaridin.
Journal of medical entomology, Volume: 51, Issue: 3		2014
A new in vitro bioassay system for discovery of novel human-use mosquito repellents.
Journal of the American Mosquito Control Association, Volume: 21, Issue: 1		2005
Field evaluation of the efficacy and persistence of insect repellents DEET, IR3535, and KBR 3023 against Anopheles gambiae complex and other Afrotropical vector mosquitoes.
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume: 98, Issue: 11		2004
Evaluation of the sensitivity of Aedes aegypti and Anopheles gambiae complex mosquitoes to two insect repellents: DEET and KBR 3023.
Tropical medicine & international health : TM & IH, Volume: 9, Issue: 3		2004
Synthesis and repellent efficacy of a new chiral piperidine analog: comparison with Deet and Bayrepel activity in human-volunteer laboratory assays against Aedes aegypti and Anopheles stephensi.
Journal of medical entomology, Volume: 40, Issue: 3		2003
Chronic toxicity and carcinogenicity testing in the Sprague-Dawley rat of a prospective insect repellant (KBR 3023) using the dermal route of exposure.
Toxicology, Dec-20, Volume: 142, Issue: 1		1999
Carcinogenicity testing in the CD-1 mouse of a prospective insect repellent (KBR 3023) using the dermal route of exposure.
Toxicology, Dec-20, Volume: 142, Issue: 1		1999
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]