metronidazole has been researched along with Abscess, Psoas in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a primary iliopsoas abscess by Streptococcus sanguis affecting an 81-year-old man cured by antibiotic therapy and aspiration procedure." | 1.42 | An 81-year-old male with iliopsoas abscess by Streptococcus sanguis. ( de Souza Lima, G; dos Santos, VM; Fachinelli, LR; Farage, L; Machado de Carvalho, MR; Nogueira de Andrade, IG, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoo, LJH | 1 |
| Zulkifli, MD | 1 |
| O'Connor, M | 1 |
| Waldron, R | 1 |
| Denes, E | 1 |
| Cypierre, A | 1 |
| Vacquier, J | 1 |
| Matt, M | 1 |
| Weinbreck, P | 1 |
| dos Santos, VM | 1 |
| Fachinelli, LR | 1 |
| Farage, L | 1 |
| de Souza Lima, G | 1 |
| Machado de Carvalho, MR | 1 |
| Nogueira de Andrade, IG | 1 |
| Yedurapa, KG | 1 |
| Nandish, VL | 1 |
4 other studies available for metronidazole and Abscess, Psoas
| Article | Year |
|---|---|
Topics: Administration, Intravenous; Administration, Oral; Aged; Anti-Bacterial Agents; Biopsy; Bone and Bon | 2019 |
Meningitis due to Fusobacterium nucleatum after a kart crash.
Topics: Anti-Infective Agents; Athletic Injuries; Bacteremia; Bacterial Translocation; Bacterial Typing Tech | 2013 |
An 81-year-old male with iliopsoas abscess by Streptococcus sanguis.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drainage; Drug Thera | 2015 |
Amoebic liver abscesses presenting with psoas abscess.
Topics: Adult; Cephalosporins; Humans; Injections, Intravenous; Liver Abscess, Amebic; Male; Metronidazole; | 1992 |