Page last updated: 2024-09-03

ah 6809 and celecoxib

ah 6809 has been researched along with celecoxib in 5 studies

Compound Research Comparison

Studies
(ah 6809)
Trials
(ah 6809)
Recent Studies (post-2010)
(ah 6809)
Studies
(celecoxib)
Trials
(celecoxib)
Recent Studies (post-2010) (celecoxib)
1631495,2738432,428

Protein Interaction Comparison

ProteinTaxonomyah 6809 (IC50)celecoxib (IC50)
Chain A, Carbonic anhydrase IIHomo sapiens (human)0.021
Prostaglandin E synthaseHomo sapiens (human)0.4825
Histone deacetylase 3Homo sapiens (human)1.637
Prostaglandin G/H synthase 1 Bos taurus (cattle)7.9667
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.057
Cytochrome c oxidase subunit 1Ovis aries (sheep)6.5
Cytochrome c oxidase subunit 2Ovis aries (sheep)0.0881
Catechol O-methyltransferaseMus musculus (house mouse)0.036
Cytochrome c oxidase subunit 2Homo sapiens (human)0.371
Carbonic anhydrase 1Homo sapiens (human)0.1555
Carbonic anhydrase 2Homo sapiens (human)0.0925
Prostaglandin G/H synthase 1Ovis aries (sheep)5.271
Procathepsin LHomo sapiens (human)0.56
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)7.308
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)0.07
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)4.295
Cytochrome P450 2D6Homo sapiens (human)1
Cytochrome P450 2C9 Homo sapiens (human)10
Calpain-2 catalytic subunitHomo sapiens (human)0.002
Alpha-2B adrenergic receptorHomo sapiens (human)1.516
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.12
Prostaglandin G/H synthase 1Mus musculus (house mouse)3.6401
Prostaglandin G/H synthase 1Homo sapiens (human)3.5499
Sodium-dependent noradrenaline transporter Homo sapiens (human)7.308
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.006
Sodium-dependent serotonin transporterHomo sapiens (human)6.276
Prostaglandin G/H synthase 2Homo sapiens (human)0.3818
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.4028
Urotensin-2 receptorRattus norvegicus (Norway rat)7.6
Histone deacetylase 4Homo sapiens (human)1.637
D(2) dopamine receptorRattus norvegicus (Norway rat)0.03
Prostaglandin G/H synthase 2Ovis aries (sheep)0.6343
Mu-type opioid receptorCavia porcellus (domestic guinea pig)7.7
Sodium-dependent dopamine transporter Homo sapiens (human)2.431
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.045
Histone deacetylase 1Homo sapiens (human)1.411
Mitogen-activated protein kinase 14Homo sapiens (human)0.81
Carbonic anhydrase 9Homo sapiens (human)0.016
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.05
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.3
Prostaglandin G/H synthase 1Canis lupus familiaris (dog)5.57
Cyclooxygenase-2 Canis lupus familiaris (dog)0.9
Histone deacetylase 7Homo sapiens (human)1.637
Histone deacetylase 2Homo sapiens (human)1.637
Carbonic anhydrase 4Bos taurus (cattle)0.2227
Polyamine deacetylase HDAC10Homo sapiens (human)1.637
Histone deacetylase 11 Homo sapiens (human)1.637
Histone deacetylase 8Homo sapiens (human)1.637
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.04
Histone deacetylase 6Homo sapiens (human)1.14
Histone deacetylase 9Homo sapiens (human)1.637
Histone deacetylase 5Homo sapiens (human)1.637

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bosetti, F; Palumbo, S; Parente, L; Toscano, CD; Weigert, R1
Edwards, RP; Kalinski, P; Muthuswamy, R; Obermajer, N; Odunsi, K1
Bi, Y; Han, M; Jiang, M; Li, S; Xu, J; Xu, X1
Arantes, EC; Faccioli, LH; Hori, JI; Paula-Silva, FW; Serezani, CH; Sorgi, CA; Zamboni, DS; Zoccal, KF1
Deng, L; Feng, D; Liang, H; Liang, J; Ling, B; Yan, K; Zhang, X1

Other Studies

5 other study(ies) available for ah 6809 and celecoxib

ArticleYear
The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination.
    Journal of neurochemistry, 2012, Volume: 121, Issue:3

    Topics: Animals; Apoptosis; Caspase 3; Cattle; Celecoxib; Chelating Agents; Cuprizone; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Demyelinating Diseases; Dinoprostone; Fluorescent Antibody Technique; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Sheath; Oligodendroglia; Postural Balance; Pyrazoles; Real-Time Polymerase Chain Reaction; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Sulfonamides; Xanthones

2012
PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment.
    Cancer research, 2011, Dec-15, Volume: 71, Issue:24

    Topics: Biphenyl Compounds; CD11b Antigen; Celecoxib; Cell Movement; Cells, Cultured; Chemokine CXCL12; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Monocytes; Myeloid Cells; Ovarian Neoplasms; Prostaglandin Antagonists; Pyrazoles; Receptors, CXCR4; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides; Tumor Cells, Cultured; Tumor Microenvironment; Xanthones

2011
Lipopolysaccharide induces inflammation and facilitates lung metastasis in a breast cancer model via the prostaglandin E2-EP2 pathway.
    Molecular medicine reports, 2015, Volume: 11, Issue:6

    Topics: Animals; Blood Vessels; Breast Neoplasms; Celecoxib; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Endothelial Cells; Female; Inflammation; Lipopolysaccharides; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Receptors, Prostaglandin E; Vascular Endothelial Growth Factor A; Xanthones

2015
Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality.
    Nature communications, 2016, Feb-23, Volume: 7

    Topics: Animals; Arachidonate 5-Lipoxygenase; Blotting, Western; Carrier Proteins; Celecoxib; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dinoprostone; In Vitro Techniques; Indoles; Indomethacin; Inflammasomes; Interleukin-1beta; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Macrophages, Peritoneal; Mice; Mice, Knockout; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphoproteins; Prostaglandin Antagonists; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Reverse Transcriptase Polymerase Chain Reaction; Scorpion Stings; Scorpion Venoms; Scorpions; Xanthones

2016
Cyclooxygenase 2 Promotes Proliferation and Invasion in Ovarian Cancer Cells via the PGE2/NF-κB Pathway.
    Cell transplantation, 2019, Volume: 28, Issue:1_suppl

    Topics: Animals; Antineoplastic Agents; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Humans; Mice, Nude; Neoplasm Grading; Neoplasm Invasiveness; NF-kappa B; Nitriles; Ovarian Neoplasms; Phosphorylation; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Sulfones; Transplantation, Heterologous; Xanthones

2019