Page last updated: 2024-09-03

ah 6809 and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

ah 6809 has been researched along with n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide in 11 studies

Compound Research Comparison

Studies
(ah 6809)
Trials
(ah 6809)
Recent Studies (post-2010)
(ah 6809)
Studies
(n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
Trials
(n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
Recent Studies (post-2010) (n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
1631491,2203229

Protein Interaction Comparison

ProteinTaxonomyah 6809 (IC50)n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide (IC50)
Prostaglandin E synthaseHomo sapiens (human)10
Prostaglandin G/H synthase 1Ovis aries (sheep)2.1
AromataseHomo sapiens (human)0.68
Prostaglandin G/H synthase 1Mus musculus (house mouse)1.67
Prostaglandin G/H synthase 1Homo sapiens (human)3
Prostaglandin G/H synthase 2Homo sapiens (human)0.9037
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4333
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.1522
Carboxypeptidase B2Homo sapiens (human)1.8
Prostaglandin E synthaseMus musculus (house mouse)0.007

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Azemovic, D; Massoumi, R; Nielsen, CK; Sjölander, A1
Hamasaki, Y; Ishii, K; Matsuo, M; Yoshida, N; Zaitsu, M1
Akaike, A; Banno, Y; Fushimi, K; Nakashima, S; Shimizu, K; Takigawa, M1
Ito, M; Iwamoto, J; Matsuoka, T; Miura, S; Mizokami, Y; Narasaka, T; Omata, T; Ootubo, T; Shimokobe, K; Takahashi, K; Takehara, H; Takeyama, H1
Destache, CJ; Ohia, SE; Opere, CA; Zhao, M1
Goldmann, O; Hecht, A; Hertzén, E; Lehne, S; Medina, E; Norrby-Teglund, A; Schmidt, H1
Liu, J; Qian, X; Zhang, J1
Li, Y; Wang, H; Wei, X; Wu, Y; Xu, Z; Yang, P; Zhao, L; Zhao, Z1
de Queiroz, DB; Duarte, GP; Ramos-Alves, FE; Santos-Rocha, J; Xavier, FE1
Li, X; Li, Y; Tan, L; Tang, T; Wang, J; Wu, Y; Xu, Z; Yang, P; Zhao, L; Zhao, Z1
Cho, MS; Choi, JY; Kang, JL; Lee, YJ; Yoon, YS1

Other Studies

11 other study(ies) available for ah 6809 and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

ArticleYear
Leukotriene D4-induced adhesion of Caco-2 cells is mediated by prostaglandin E2 and upregulation of alpha2beta1-integrin.
    Experimental cell research, 2003, Oct-01, Volume: 289, Issue:2

    Topics: Caco-2 Cells; Carcinoma; Cell Adhesion; Colitis; Collagen Type I; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Extracellular Matrix; Humans; Integrin alpha2beta1; Isoenzymes; Leukotriene D4; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Receptors, Leukotriene; Sulfonamides; Up-Regulation; Xanthenes; Xanthones

2003
Inhibition of human glioma cell growth by a PHS-2 inhibitor, NS398, and a prostaglandin E receptor subtype EP1-selective antagonist, SC51089.
    Journal of neuro-oncology, 2004, Volume: 66, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Glioma; Humans; Hydrazines; Isoenzymes; Membrane Proteins; Mice; Mice, SCID; Nitrobenzenes; Oxazepines; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Sulfonamides; Transplantation, Heterologous; Tumor Cells, Cultured; Xanthones

2004
Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs.
    Osteoarthritis and cartilage, 2004, Volume: 12, Issue:11

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Calpain; Cell Line, Tumor; Chondrocytes; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diclofenac; Dinoprostone; Humans; Nitrobenzenes; Phenylpropionates; Prostaglandin Antagonists; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthones

2004
Involvement of cyclooxygenase-2--prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:12

    Topics: Adenocarcinoma; Arachidonic Acid; Biphenyl Compounds; Cell Line, Tumor; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Fibroblasts; Gene Expression Regulation, Neoplastic; Helicobacter pylori; Humans; Interleukin-8; Nitrobenzenes; Prostaglandin Antagonists; Receptors, Prostaglandin E; RNA, Messenger; Stomach Neoplasms; Sulfonamides; Xanthones

2006
Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo.
    Neurochemical research, 2009, Volume: 34, Issue:12

    Topics: Animals; Benzofurans; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Fatty Acids, Unsaturated; Flurbiprofen; Glutamic Acid; Glutamine; Glycine; Hydrazines; Isoprostanes; Neurotransmitter Agents; Nitrobenzenes; Prostaglandins; Receptors, Prostaglandin; Retina; Sulfonamides; Xanthones

2009
Inducible cyclooxygenase released prostaglandin E2 modulates the severity of infection caused by Streptococcus pyogenes.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Aug-15, Volume: 185, Issue:4

    Topics: Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Female; Host-Pathogen Interactions; Humans; Immunohistochemistry; Macrophages; Mice; Mice, Inbred C3H; Mice, Knockout; Nitrobenzenes; Prostaglandin Antagonists; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Severity of Illness Index; Streptococcal Infections; Streptococcus pyogenes; Sulfonamides; Xanthones

2010
Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway.
    The Journal of biological chemistry, 2011, Jan-21, Volume: 286, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Cell Line; Chemokine CCL5; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Interferon-gamma; Interleukin-2; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrobenzenes; Prostaglandin Antagonists; Protein Kinase Inhibitors; Shock, Septic; Signal Transduction; Sulfonamides; Tumor Escape; Xanthones

2011
Involvement of COX-2/PGE2 signalling in hypoxia-induced angiogenic response in endothelial cells.
    Journal of cellular and molecular medicine, 2012, Volume: 16, Issue:8

    Topics: Aquaporin 1; Cell Hypoxia; Cell Movement; Cell Proliferation; Cell Shape; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Neovascularization, Physiologic; Nitrobenzenes; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors; Transcription, Genetic; Vascular Endothelial Growth Factor A; Xanthones

2012
Increased cyclooxygenase-2-derived prostanoids contributes to the hyperreactivity to noradrenaline in mesenteric resistance arteries from offspring of diabetic rats.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Dinoprost; Endothelial Cells; Female; Immunoenzyme Techniques; Indomethacin; Male; Mesenteric Arteries; Nitrobenzenes; Norepinephrine; Pregnancy; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Sulfonamides; Thromboxane A2; Xanthones

2012
Coculture with endothelial cells enhances osteogenic differentiation of periodontal ligament stem cells via cyclooxygenase-2/prostaglandin E2/vascular endothelial growth factor signaling under hypoxia.
    Journal of periodontology, 2013, Volume: 84, Issue:12

    Topics: Angiogenesis Inhibitors; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endothelial Cells; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Nitrobenzenes; Osteogenesis; Periodontal Ligament; Prostaglandin Antagonists; Protein Kinase Inhibitors; Pyrroles; Signal Transduction; Stem Cells; Sulfonamides; Thiophenes; Triazoles; Vascular Endothelial Growth Factor A; Xanthones

2013
Coordinated induction of cyclooxygenase-2/prostaglandin E2 and hepatocyte growth factor by apoptotic cells prevents lung fibrosis.
    Journal of leukocyte biology, 2013, Volume: 94, Issue:5

    Topics: Animals; Apoptosis; Bleomycin; Cyclooxygenase 2; Dinoprostone; Hepatocyte Growth Factor; Indoles; Male; Mice; Mice, Inbred C57BL; Nitrobenzenes; Pulmonary Fibrosis; Signal Transduction; Sulfonamides; Sulfones; Xanthones

2013