Page last updated: 2024-09-03

ah 6809 and butaprost

ah 6809 has been researched along with butaprost in 20 studies

Compound Research Comparison

Studies
(ah 6809)
Trials
(ah 6809)
Recent Studies (post-2010)
(ah 6809)
Studies
(butaprost)
Trials
(butaprost)
Recent Studies (post-2010) (butaprost)
163149603
163149161046

Protein Interaction Comparison

ProteinTaxonomyah 6809 (IC50)butaprost (IC50)
Prostacyclin receptorHomo sapiens (human)0.037

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's10 (50.00)29.6817
2010's6 (30.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Ganesh, T1
Koda, H; Kumazawa, T; Mizumura, K1
Fukusako, H; Koda, H; Kumazawa, T; Mizumura, K1
Breuiller-Fouché, M; Cabrol, D; Dallot, E; Ferré, F; Leroy, MJ; Schmitz, T1
Andelfinger, G; Bouayad, A; Chemtob, S; Clyman, RI; Fouron, JC; Gobeil, F; Kajino, H; Skoll, A; Varma, DR; Vazquez, A; Waleh, N1
Abayasekara, DR; Bernal, AL; Harris, TE; Michael, AE; Squires, PE1
Heinemann, A; Holzer, P; Peskar, BA; Shahbazian, A1
Belvisi, MG; Catley, MC; Clarke, DL; Giembycz, MA; Newton, R; Yacoub, MH1
Akaike, A; Banno, Y; Fushimi, K; Nakashima, S; Shimizu, K; Takigawa, M1
Berliner, JA; Cruz, D; Dun, M; Gharavi, N; Koroniak, L; Li, R; Montoya, D; Mouillesseaux, KP1
Abayasekara, DR; Bernal, AL; Chandras, C; Harris, TE; Michael, AE1
Bradding, P; Brightling, CE; Cockerill, SL; Cruse, G; Duffy, SM1
Juvet, SC; Lee, BP; Zhang, L1
Baun, M; Gupta, S; Jansen-Olesen, I; Myren, M; Olesen, J; Ploug, KB1
Brant, KA; Fabisiak, JP1
Chae, IG; Chun, KS; Kwon, TK; Min, KJ; Woo, SM1
Chadee, K; Lejeune, M; Moreau, F1
Cao, J; Deng, Y; Fu, C; Gao, L; Gao, R; Liu, B; Mao, W; Shen, Y; Wu, J; Wu, X; Zhang, N; Zhang, S; Zhang, Y1
Qu, J; Reinach, PS; Srinivasalu, N; Su, Y; Xu, R; Zhang, S; Zhou, X; Zhu, Y1
Cao, J; Feng, S; Fu, C; Li, Q; Liu, B; Mao, W; Zhang, S; Zhao, J1

Reviews

1 review(s) available for ah 6809 and butaprost

ArticleYear
Prostanoid receptor EP2 as a therapeutic target.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Eye Diseases; Gene Knockout Techniques; Humans; Molecular Targeted Therapy; Neurodegenerative Diseases; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Stroke

2014

Other Studies

19 other study(ies) available for ah 6809 and butaprost

ArticleYear
Involvement of EP3 subtype of prostaglandin E receptors in PGE2-induced enhancement of the bradykinin response of nociceptors.
    Brain research, 1993, Dec-31, Volume: 632, Issue:1-2

    Topics: Alprostadil; Animals; Bradykinin; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Epididymis; Hot Temperature; In Vitro Techniques; Male; Nociceptors; Physical Stimulation; Prostaglandin Antagonists; Receptors, Prostaglandin E; Testis; Xanthenes; Xanthones

1993
EP receptor subtypes implicated in the PGE2-induced sensitization of polymodal receptors in response to bradykinin and heat.
    Journal of neurophysiology, 1996, Volume: 75, Issue:6

    Topics: Alprostadil; Animals; Bradykinin; Cyclic AMP; Dinoprostone; Dogs; Hot Temperature; Nociceptors; Prostaglandin Antagonists; Prostaglandins E, Synthetic; Receptors, Prostaglandin E; Xanthenes; Xanthones

1996
EP(4) receptors mediate prostaglandin E(2)-stimulated glycosaminoglycan synthesis in human cervical fibroblasts in culture.
    Molecular human reproduction, 2001, Volume: 7, Issue:4

    Topics: Alprostadil; Biphenyl Compounds; Cells, Cultured; Cervix Uteri; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Female; Fibroblasts; Glycosaminoglycans; Humans; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Xanthenes; Xanthones

2001
Characterization of PGE2 receptors in fetal and newborn lamb ductus arteriosus.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Alprostadil; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Anti-Ulcer Agents; Binding, Competitive; Biphenyl Compounds; Colforsin; Dinoprost; Ductus Arteriosus; Female; Fetus; Polymerase Chain Reaction; Potassium Channels; Pregnancy; Prostaglandin Antagonists; Prostaglandins E, Synthetic; Radioligand Assay; Receptors, Prostaglandin E; Sheep; Tritium; Vasoconstriction; Xanthenes; Xanthones

2001
Human granulosa-lutein cells express functional EP1 and EP2 prostaglandin receptors.
    Biochemical and biophysical research communications, 2001, Aug-03, Volume: 285, Issue:5

    Topics: 16,16-Dimethylprostaglandin E2; Alprostadil; Calcium; Cells, Cultured; Cyclic AMP; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Female; Granulosa Cells; Humans; Intracellular Fluid; Lutein; Progesterone; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Xanthenes; Xanthones

2001
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dinoprostone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Guinea Pigs; Hydantoins; Hydrazines; Iloprost; In Vitro Techniques; Intestine, Small; Leukotriene Antagonists; Leukotriene D4; Male; Oxazepines; Peristalsis; Prostaglandin D2; Prostaglandins A; Receptors, Leukotriene; Receptors, Prostaglandin; Xanthenes; Xanthones; Yohimbine

2002
Identification in human airways smooth muscle cells of the prostanoid receptor and signalling pathway through which PGE2 inhibits the release of GM-CSF.
    British journal of pharmacology, 2004, Volume: 141, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenoviridae; Adolescent; Adult; Aged; Alprostadil; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Female; Gene Expression; Genetic Vectors; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Interleukin-1; Isoquinolines; Male; Middle Aged; Misoprostol; Myocytes, Smooth Muscle; Prostaglandins E, Synthetic; Protein Isoforms; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Sulfonamides; Trachea; Xanthones

2004
Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs.
    Osteoarthritis and cartilage, 2004, Volume: 12, Issue:11

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Calpain; Cell Line, Tumor; Chondrocytes; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diclofenac; Dinoprostone; Humans; Nitrobenzenes; Phenylpropionates; Prostaglandin Antagonists; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthones

2004
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC.
    Circulation research, 2006, Mar-17, Volume: 98, Issue:5

    Topics: Alprostadil; Atherosclerosis; Cells, Cultured; Dinoprostone; Foam Cells; Humans; Interleukin-10; Isoprostanes; Macrophages; Monocytes; Oxidation-Reduction; Phosphatidylcholines; Phospholipid Ethers; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthones

2006
PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11beta-hydroxysteroid dehydrogenase activity by prostaglandin E2 in human granulosa lutein cells.
    The Journal of endocrinology, 2007, Volume: 194, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Alprostadil; Cells, Cultured; Cortisone; Cyclic AMP; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Luteal Cells; Progesterone; Prostaglandin Antagonists; Prostaglandins E, Synthetic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Xanthones

2007
Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration.
    European journal of immunology, 2008, Volume: 38, Issue:9

    Topics: Alprostadil; Benzimidazoles; Calcium Channel Agonists; Cell Movement; Chemotaxis; Dinoprostone; Histamine Release; Humans; Mast Cells; Potassium Channels; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Xanthones

2008
Prostaglandin E2 signaling through E prostanoid receptor 2 impairs proliferative response of double negative regulatory T cells.
    International immunopharmacology, 2009, Volume: 9, Issue:5

    Topics: Alprostadil; Animals; CD4 Antigens; CD8 Antigens; Cell Proliferation; Clone Cells; Cytotoxicity, Immunologic; Dinoprostone; Immunomagnetic Separation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prostaglandin Antagonists; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; T-Lymphocytes, Regulatory; Xanthones

2009
Functional and molecular characterization of prostaglandin E2 dilatory receptors in the rat craniovascular system in relevance to migraine.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:9

    Topics: Adenine; Alprostadil; Animals; Cerebral Arteries; Dinoprostone; Enzyme Inhibitors; Male; Meningeal Arteries; Migraine Disorders; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Trigeminal Nerve; Vasodilation; Xanthones

2010
Role of hypoxia-inducible factor 1, α subunit and cAMP-response element binding protein 1 in synergistic release of interleukin 8 by prostaglandin E2 and nickel in lung fibroblasts.
    American journal of respiratory cell and molecular biology, 2013, Volume: 49, Issue:1

    Topics: Alprostadil; Biomimetics; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dinoprostone; Drug Synergism; Fibroblasts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-8; Lung; Nickel; p38 Mitogen-Activated Protein Kinases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Xanthones

2013
Silymarin suppresses the PGE2 -induced cell migration through inhibition of EP2 activation; G protein-dependent PKA-CREB and G protein-independent Src-STAT3 signal pathways.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:3

    Topics: Alprostadil; Antioxidants; Benzodioxoles; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; HCT116 Cells; HT29 Cells; Humans; Integrases; Kidney Neoplasms; Phosphorylation; Prostaglandin Antagonists; Quinazolines; Receptors, Prostaglandin E, EP2 Subtype; RNA Interference; RNA, Small Interfering; Signal Transduction; Silymarin; src-Family Kinases; STAT3 Transcription Factor; Wound Healing; Xanthones

2015
Loss of EP2 receptor subtype in colonic cells compromise epithelial barrier integrity by altering claudin-4.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Alprostadil; Caco-2 Cells; Cell Membrane Permeability; Claudin-4; Cytokines; Down-Regulation; Humans; Interferon-gamma; Receptors, Prostaglandin E, EP2 Subtype; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tight Junctions; Xanthones

2014
PTGER2 activation induces PTGS-2 and growth factor gene expression in endometrial epithelial cells of cattle.
    Animal reproduction science, 2017, Volume: 187

    Topics: Alprostadil; Animals; Cattle; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Endometrium; Epithelial Cells; Female; Gene Expression Regulation; Intercellular Signaling Peptides and Proteins; Interleukin-8; MAP Kinase Signaling System; Prostaglandin Antagonists; Receptors, Prostaglandin E, EP2 Subtype; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Xanthones

2017
Crosstalk between EP2 and PPARα Modulates Hypoxic Signaling and Myopia Development in Guinea Pigs.
    Investigative ophthalmology & visual science, 2020, 07-01, Volume: 61, Issue:8

    Topics: Alprostadil; Animals; Cyclic AMP; Extracellular Matrix; Guinea Pigs; Hypoxia-Inducible Factor 1, alpha Subunit; Myopia, Degenerative; PPAR alpha; Prostaglandin Antagonists; Prostaglandins E, Synthetic; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Xanthones

2020
Proliferation of bovine endometrial epithelial cells is promoted by prostaglandin E
    Prostaglandins, leukotrienes, and essential fatty acids, 2021, Volume: 174

    Topics: Alprostadil; Aminopyridines; Animals; Cattle; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinases; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endometrium; Epithelial Cells; Female; Proliferating Cell Nuclear Antigen; Purines; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Up-Regulation; Xanthones

2021