ah 6809 has been researched along with dinoprostone in 116 studies
| Studies (ah 6809) | Trials (ah 6809) | Recent Studies (post-2010) (ah 6809) | Studies (dinoprostone) | Trials (dinoprostone) | Recent Studies (post-2010) (dinoprostone) |
|---|---|---|---|---|---|
| 163 | 1 | 49 | 29,105 | 1,346 | 6,357 |
| Protein | Taxonomy | ah 6809 (IC50) | dinoprostone (IC50) |
|---|---|---|---|
| Prostaglandin E2 receptor EP1 subtype | Homo sapiens (human) | 0.0155 | |
| Prostaglandin E2 receptor EP4 subtype | Homo sapiens (human) | 0.0031 | |
| Prostaglandin E2 receptor EP4 subtype | Rattus norvegicus (Norway rat) | 0.0021 | |
| Prostaglandin E2 receptor EP3 subtype | Homo sapiens (human) | 0.002 | |
| Prostaglandin E2 receptor EP2 subtype | Homo sapiens (human) | 0.0087 | |
| Prostacyclin receptor | Homo sapiens (human) | 0.26 | |
| Prostaglandin E2 receptor EP2 subtype | Rattus norvegicus (Norway rat) | 0.0052 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.72) | 18.7374 |
| 1990's | 26 (22.41) | 18.2507 |
| 2000's | 49 (42.24) | 29.6817 |
| 2010's | 37 (31.90) | 24.3611 |
| 2020's | 2 (1.72) | 2.80 |
| Authors | Studies |
|---|---|
| Hirata, M; Kiriyama, M; Kobayashi, T; Narumiya, S; Sugimoto, Y; Ushikubi, F | 1 |
| Abramovitz, M; Boie, Y; Metters, KM; Neuschäfer-Rube, F; Püschel, GP; Sawyer, N; Slipetz, DM; Stocco, R; Ungrin, MD | 1 |
| Abramovitz, M; Adam, M; Belley, M; Boie, Y; Carrière, M; Denis, D; Dufresne, C; Gallant, M; Gareau, Y; Godbout, C; Juteau, H; Labelle, M; Lamontagne, S; Metters, KM; Ouimet, N; Rochette, C; Ruel, R; Sawyer, N; Tremblay, NM | 1 |
| Davis, TL; Sharif, NA | 1 |
| Ganesh, T | 1 |
| Baxter, GS; Clayton, JK; Marshall, K; Sangha, R; Senior, J | 1 |
| Jones, RL; Lawrence, RA | 1 |
| Malinowska, B; Molderings, G; Schlicker, E | 1 |
| Coleman, RA; Humphrey, PP; Strong, P | 1 |
| Hori, T; Matsuda, T; Nakashima, T | 1 |
| Matsumura, H | 1 |
| Jumblatt, MM; Paterson, CA | 1 |
| Beasley, TC; Biddulph, DM; Capehart, AA | 1 |
| Choi, WS; Hayaishi, O; Honda, K; Inoué, S; Matsumura, H; Sakai, T | 1 |
| Coleman, RA; Kennedy, I; Sheldrick, RL | 1 |
| Burkey, TH; Pepperl, DJ; Regan, JW; Woodward, DF | 1 |
| Akarsu, ES; Ayhan, IH | 1 |
| Crankshaw, DJ; Gaspar, V | 1 |
| Hayaishi, O; Hyodo, M; Ito, S; Minami, T; Nishihara, I; Sakamoto, K | 1 |
| Coca-Prados, M; Jumblatt, MM; Neltner, AA; Paterson, CA | 1 |
| al-Zadjali, KH; Imler, MP; Ohia, SE | 1 |
| Koda, H; Kumazawa, T; Mizumura, K | 1 |
| Jones, RL; Matthews, JS | 1 |
| Fukusako, H; Koda, H; Kumazawa, T; Mizumura, K | 1 |
| Mazar-Feldman, J; Rimon, G | 1 |
| Coleman, R; Hammond, TG; Horton, AA; Hutchinson, SM | 1 |
| Berrino, L; Bräutigam, M; Griepenkerl, I; Jäger, R; Möhlig, A; Racké, K; Reimann, A | 1 |
| Barnes, PJ; Giembycz, MA; Meja, KK | 1 |
| Leff, AR; Mitchell, RW; Ndukwu, IM; White, SR | 1 |
| Artibani, W; Corsi, M; Palea, S; Pietra, C; Romano, O; Toson, G; Trist, DG | 1 |
| Beadle, RE; Holmes, EP; Seahorn, TL; Venugopalan, CS | 1 |
| Aussel, C; Ekindjian, OG; Hernvann, A; Le Maire, V; Le Marechal, H; Russo-Marie, F; Solito, E | 1 |
| Kinsella, BT; Walsh, MT | 1 |
| Grundy, D; Haupt, W; Jiang, W; Kreis, ME | 1 |
| Henry, PJ; Knight, DA; Lan, RS; Stewart, GA | 1 |
| Breuiller-Fouché, M; Cabrol, D; Dallot, E; Ferré, F; Leroy, MJ; Schmitz, T | 1 |
| Abayasekara, DR; Bernal, AL; Harris, TE; Michael, AE; Squires, PE | 1 |
| Halm, DR; Halm, ST | 1 |
| Brink, C; de Montpreville, V; Norel, X; Walch, L | 1 |
| Moreno, JJ; Sanchez, T | 1 |
| Casibang, M; Moody, TW | 1 |
| Manning, BP; Mawe, GM; Sharkey, KA | 1 |
| Heinemann, A; Holzer, P; Peskar, BA; Shahbazian, A | 1 |
| DeMasi, GM; Hardwick, JC; Jelson, GS; Sager, KL | 1 |
| Bonewald, LF; Cheng, B; Cherian, PP; Gu, S; Jiang, JX; Sprague, E | 1 |
| Chakrabarti, S; Chakraborty, C; Lala, PK; Timoshenko, AV; Xu, G | 1 |
| Azemovic, D; Massoumi, R; Nielsen, CK; Sjölander, A | 1 |
| Carmignoto, G; Fellin, T; Gobbo, S; Pozzan, T; Sebelin, A; Zonta, M | 1 |
| Belvisi, MG; Clarke, DL; Giembycz, MA; Patel, HJ | 1 |
| Hamasaki, Y; Ishii, K; Matsuo, M; Yoshida, N; Zaitsu, M | 1 |
| Belvisi, MG; Catley, MC; Clarke, DL; Giembycz, MA; Newton, R; Yacoub, MH | 1 |
| Arjona, AA; Lee, RK; Pooler, AM; Wurtman, RJ | 1 |
| Akaike, A; Banno, Y; Fushimi, K; Nakashima, S; Shimizu, K; Takigawa, M | 1 |
| Jabre, A; Jadhav, V; Lee, TJ; Lin, SZ | 1 |
| Enck, P; Glatzle, J; Grundy, D; Kreis, M; Mueller, MH; Wang, B | 1 |
| Abruzzese, JL; Cognetti, F; McConkey, DJ; Nawrocki, ST; Pino, MS; Xiong, HQ | 1 |
| Berliner, JA; Cruz, D; Dun, M; Gharavi, N; Koroniak, L; Li, R; Montoya, D; Mouillesseaux, KP | 1 |
| Matlhagela, K; Taub, M | 1 |
| Ito, M; Iwamoto, J; Matsuoka, T; Miura, S; Mizokami, Y; Narasaka, T; Omata, T; Ootubo, T; Shimokobe, K; Takahashi, K; Takehara, H; Takeyama, H | 1 |
| Lee, LY; Zhang, G | 1 |
| Farley, JM; Liu, H | 1 |
| Kassardjian, A; Kreydiyyeh, SI; Riman, S; Serhan, M | 1 |
| Abayasekara, DR; Bernal, AL; Chandras, C; Harris, TE; Michael, AE | 1 |
| Feletou, M; Jensen, BL; Leung, GP; Man, RY; Skott, O; Tang, EH; Vanhoutte, PM | 1 |
| Grant, V; Jabbour, HN; Sales, KJ | 1 |
| Iwamoto, J; Matsuoka, T; Matsuzaki, Y; Mizokami, Y; Takahashi, K | 1 |
| Agren, P; Blanco, CE; Cogolludo, AL; van der Sterren, S; Villamor, E | 1 |
| Bradding, P; Brightling, CE; Cockerill, SL; Cruse, G; Duffy, SM | 1 |
| Kobayashi, K; Matsuoka, T; Nakamura, H; Odaka, T; Takahashi, K | 1 |
| Kang, JH; Son, KA; Yang, MP | 1 |
| Cs-Szabo, G; Ellman, M; Im, HJ; Li, X; Muddasani, P; van Wijnen, AJ; Wang, JH | 1 |
| Hou, LK; Jin, HM; Qian, RZ; Wang, XH; Yue, F; Zhang, GP | 1 |
| Bagi, Z; Edes, I; Erdei, N; Feher, A; Henrion, D; Kaley, G; Koller, A; Papp, Z; Rutkai, I | 1 |
| Flood, P; Hong, JS; Hu, X; Langenbach, R; Lee, C; Qian, L; Wilson, B; Zhang, D | 1 |
| Destache, CJ; Ohia, SE; Opere, CA; Zhao, M | 1 |
| Juvet, SC; Lee, BP; Zhang, L | 1 |
| Kaur, C; Li, P; Ling, EA; Lu, J; Sivakumar, V; Tan, KL | 1 |
| Belvisi, MG; Birrell, MA; Maher, SA | 1 |
| Cho, EA; Juhnn, YS; Kim, SH; Kim, WH; Oh, JM; Song, YS | 1 |
| Goldmann, O; Hecht, A; Hertzén, E; Lehne, S; Medina, E; Norrby-Teglund, A; Schmidt, H | 1 |
| Baun, M; Gupta, S; Jansen-Olesen, I; Myren, M; Olesen, J; Ploug, KB | 1 |
| Liu, J; Qian, X; Zhang, J | 1 |
| Belvisi, MG; Birrell, MA; Buckley, J; Clarke, DL; Maher, SA; Nials, AT | 1 |
| Brain, KL; Kobayter, S; Young, JS | 1 |
| Bosetti, F; Palumbo, S; Parente, L; Toscano, CD; Weigert, R | 1 |
| Jiang, XL; Li, XL; Liu, JL; Lu, JM; Song, XJ; Wang, HF | 2 |
| Hausermann, L; St-Louis, J | 1 |
| Edwards, RP; Kalinski, P; Muthuswamy, R; Obermajer, N; Odunsi, K | 1 |
| Li, Y; Wang, H; Wei, X; Wu, Y; Xu, Z; Yang, P; Zhao, L; Zhao, Z | 1 |
| Henry, PJ; Mann, TS; Taylor, SJ | 1 |
| Aronoff, DM; Okunishi, K; Peters-Golden, M; Serezani, CH; Zaslona, Z | 1 |
| Lee, YS; Shehzad, A; Yeo, HS | 1 |
| Brant, KA; Fabisiak, JP | 1 |
| Li, X; Li, Y; Tan, L; Tang, T; Wang, J; Wu, Y; Xu, Z; Yang, P; Zhao, L; Zhao, Z | 1 |
| Bhatnagar, A; Hellmann, J; Rane, M; Spite, M; Tang, Y; Zhang, MJ | 1 |
| Battani, KA; Lindgren, CA; Morford, JJ; Newman, ZL; Ryan, SB; Su, Z | 1 |
| Cho, MS; Choi, JY; Kang, JL; Lee, YJ; Yoon, YS | 1 |
| Gu, Y; Han, Y; Ma, G; Shi, H; Tang, C; Wang, Q; Yan, G | 1 |
| Chae, IG; Chun, KS; Kwon, TK; Min, KJ; Woo, SM | 1 |
| Chi, PL; Chien, PT; Hsieh, HL; Yang, CM | 1 |
| Jin, YH; Jin, Z; Kim, S; Lee, G; Park, CS; Park, YS | 1 |
| Bi, Y; Han, M; Jiang, M; Li, S; Xu, J; Xu, X | 1 |
| Amadio, P; Amato, M; Baldassarre, D; Barbieri, SS; Gianellini, S; Squellerio, I; Tarantino, E; Tremoli, E; Weksler, BB; Zacchi, E | 1 |
| Liu, Y; Shen, L | 1 |
| An, N; Chen, D; Fan, J; Li, J; Liu, C; Luo, J; Su, W; Wang, H; Zhao, J; Zhou, Y | 1 |
| Allison, S; Hoang, KG; Murray, M; Petrovic, N | 1 |
| Arantes, EC; Faccioli, LH; Hori, JI; Paula-Silva, FW; Serezani, CH; Sorgi, CA; Zamboni, DS; Zoccal, KF | 1 |
| Gong, Y; Liu, M; Quan, S; Wang, J; Wei, JY; Xie, D; Yu, YH | 1 |
| Cao, J; Deng, Y; Fu, C; Gao, L; Gao, R; Liu, B; Mao, W; Shen, Y; Wu, J; Wu, X; Zhang, N; Zhang, S; Zhang, Y | 1 |
| Chen, X; Chen, XL; Guo, NF; Liu, J; Wu, JH; Zhang, YD; Zhu, XL | 1 |
| Jiang, H; Lai, J; Li, H; Li, P; Wu, D; Wu, H; Yu, J | 1 |
| Gao, L; Li, X; Liang, X; Ma, C; Xie, T; Yang, X | 1 |
| Deng, L; Feng, D; Liang, H; Liang, J; Ling, B; Yan, K; Zhang, X | 1 |
| Arthur, S; Haynes, J; Nepal, N; Palaniappan, B; Sundaram, U | 1 |
| Cao, J; Feng, S; Fu, C; Li, Q; Liu, B; Mao, W; Zhang, S; Zhao, J | 1 |
2 review(s) available for ah 6809 and dinoprostone
| Article | Year |
|---|---|
Prostanoid receptor EP2 as a therapeutic target.
Topics: Animals; Anti-Inflammatory Agents; Eye Diseases; Gene Knockout Techniques; Humans; Molecular Targeted Therapy; Neurodegenerative Diseases; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Stroke | 2014 |
[Role of prostaglandins D2 and E2 in the regulation of sleep].
Topics: Animals; Arousal; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Norepinephrine; Prostaglandin Antagonists; Prostaglandin D2; Sleep; Xanthenes; Xanthones | 1992 |
1 trial(s) available for ah 6809 and dinoprostone
| Article | Year |
|---|---|
Production of prostaglandin E2 induced by cigarette smoke modulates tissue factor expression and activity in endothelial cells.
Topics: Adult; Aged; Aged, 80 and over; Animals; Dinoprostone; Endothelial Cells; Female; Gene Expression Regulation; Humans; Hydrazines; Interleukin-1beta; Male; Mice; Middle Aged; Myocardium; Oxazepines; Sirtuin 1; Smoking; Thromboplastin; Thrombosis; Xanthones | 2015 |
113 other study(ies) available for ah 6809 and dinoprostone
| Article | Year |
|---|---|
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
Topics: Animals; CHO Cells; Cricetinae; Ligands; Mice; Prostaglandins; Receptors, Prostaglandin; Transfection | 1997 |
Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes.
Topics: Aequorin; Amino Acid Sequence; Animals; Blotting, Northern; Cell Line; Cell Membrane; Cloning, Molecular; Dinoprostone; Humans; Kidney; Ligands; Liver; Luminescent Measurements; Male; Mice; Molecular Sequence Data; Radioligand Assay; Rats; Receptors, Prostaglandin E; Spleen | 1997 |
The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs.
Topics: Binding, Competitive; Cell Line; Cell Membrane; Humans; Ligands; Prostaglandins; Radioligand Assay; Receptors, Prostaglandin; Recombinant Proteins | 2000 |
Cloned human EP1 prostanoid receptor pharmacology characterized using radioligand binding techniques.
Topics: Algorithms; Alprostadil; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Dinoprost; Dinoprostone; DNA, Recombinant; Dose-Response Relationship, Drug; Epoprostenol; Humans; Ligands; Prostaglandin D2; Prostaglandins E; Radioligand Assay; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Tritium | 2002 |
In vitro characterization of prostanoid EP-receptors in the non-pregnant human myometrium.
Topics: Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Iloprost; In Vitro Techniques; Misoprostol; Myometrium; Receptors, Prostaglandin E; Rioprostil; Xanthenes; Xanthones | 1991 |
Investigation of the prostaglandin E (EP-) receptor subtype mediating relaxation of the rabbit jugular vein.
Topics: Animals; Chickens; Dinoprostone; Ileum; In Vitro Techniques; Jugular Veins; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandins; Rabbits; Receptors, Prostaglandin; Receptors, Prostaglandin E; Xanthenes; Xanthones | 1992 |
Inhibition of noradrenaline release in the rat vena cava via prostanoid receptors of the EP3-subtype.
Topics: Alprostadil; Animals; Dinoprost; Dinoprostone; Electric Stimulation; Indomethacin; Misoprostol; Norepinephrine; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandins; Rats; Receptors, Prostaglandin; Receptors, Prostaglandin E; Vena Cava, Inferior; Xanthenes; Xanthones; Yohimbine | 1992 |
Prostanoid-induced inhibition of lipolysis in rat isolated adipocytes: probable involvement of EP3 receptors.
Topics: Adipose Tissue; Animals; Dinoprostone; Enprostil; In Vitro Techniques; Lipolysis; Prostaglandin Antagonists; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Xanthenes; Xanthones | 1992 |
Thermal and PGE2 sensitivity of the organum vasculosum lamina terminalis region and preoptic area in rat brain slices.
Topics: Animals; Body Temperature; Cold Temperature; Dinoprostone; Hot Temperature; Hypothalamus; In Vitro Techniques; Male; Neurons; Preoptic Area; Prostaglandin Antagonists; Rats; Rats, Wistar; Xanthenes; Xanthones | 1992 |
Prostaglandin E2 effects on corneal endothelial cyclic adenosine monophosphate synthesis and cell shape are mediated by a receptor of the EP2 subtype.
Topics: Animals; Cells, Cultured; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Endothelium, Corneal; Prostaglandins E, Synthetic; Rabbits; Receptors, Prostaglandin; Receptors, Prostaglandin E; Xanthenes; Xanthones | 1991 |
Comparative effects of cytosine arabinoside and a prostaglandin E2 antagonist, AH6809, on chondrogenesis in serum-free cultures of chick limb mesenchyme.
Topics: Animals; Cartilage; Cell Differentiation; Cell Division; Cells, Cultured; Chick Embryo; Cytarabine; Dinoprostone; DNA; Embryonic and Fetal Development; Extremities; Mesoderm; Prostaglandin Antagonists; Receptors, Prostaglandin; Xanthenes; Xanthones | 1991 |
Evidence that brain prostaglandin E2 is involved in physiological sleep-wake regulation in rats.
Topics: Animals; Body Temperature; Brain; Circadian Rhythm; Dinoprostone; Male; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Reference Values; Sleep; Sleep, REM; Wakefulness; Xanthenes; Xanthones | 1989 |
New evidence with selective agonists and antagonists for the subclassification of PGE2-sensitive (EP) receptors.
Topics: Alprostadil; Animals; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; In Vitro Techniques; Muscle Contraction; Prostaglandins E; Prostaglandins E, Synthetic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Xanthenes; Xanthones | 1987 |
6-Isopropoxy-9-oxoxanthene-2-carboxylic acid (AH 6809), a human EP2 receptor antagonist.
Topics: Animals; Binding, Competitive; Cells, Cultured; Cyclic AMP; Dinoprostone; Humans; Kinetics; Prostaglandin Antagonists; Receptors, Prostaglandin E; Tritium; Xanthenes; Xanthones | 1995 |
Iloprost, a stable analogue of PGI2, potentiates the hyperthermic effect of PGE2 in rats.
Topics: Animals; Body Temperature; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Iloprost; Indomethacin; Injections; Injections, Intraventricular; Male; Preoptic Area; Prostaglandin Antagonists; Rats; Rats, Wistar; Receptors, Prostaglandin E; Xanthenes; Xanthones | 1993 |
Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Cloprostenol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Female; Iloprost; In Vitro Techniques; Isoproterenol; Myometrium; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins E, Synthetic; Prostaglandins, Synthetic; Receptors, Prostaglandin; Sheep; Thromboxane A2; Thromboxanes; Uterine Contraction; Vasoconstrictor Agents; Xanthenes; Xanthones | 1995 |
Blockade by ONO-NT-012, a unique prostanoid analogue, of prostaglandin E2-induced allodynia in conscious mice.
Topics: Analysis of Variance; Animals; Bridged Bicyclo Compounds; Dinoprostone; Hyperalgesia; Injections, Spinal; Male; Mice; Pain; Skin; Styrenes; Xanthenes; Xanthones | 1995 |
EP2-receptor stimulated cyclic AMP synthesis in cultured human non-pigmented ciliary epithelium.
Topics: Cell Line, Transformed; Ciliary Body; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Epithelium; Humans; Prostaglandin Antagonists; Receptors, Prostaglandin E; Xanthenes; Xanthones | 1994 |
Inhibitory effect of prostaglandins on dopamine release from the retina.
Topics: Animals; Apomorphine; Cyclooxygenase Inhibitors; Dinoprostone; Dopamine; Electric Stimulation; Flurbiprofen; In Vitro Techniques; Male; Melatonin; Prostaglandin Antagonists; Prostaglandins; Rabbits; Receptors, Cell Surface; Receptors, Dopamine D2; Receptors, Melatonin; Receptors, Prostaglandin; Retina; Xanthenes; Xanthones | 1994 |
Involvement of EP3 subtype of prostaglandin E receptors in PGE2-induced enhancement of the bradykinin response of nociceptors.
Topics: Alprostadil; Animals; Bradykinin; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Epididymis; Hot Temperature; In Vitro Techniques; Male; Nociceptors; Physical Stimulation; Prostaglandin Antagonists; Receptors, Prostaglandin E; Testis; Xanthenes; Xanthones | 1993 |
Potentiation of aggregation and inhibition of adenylate cyclase in human platelets by prostaglandin E analogues.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Dinoprostone; Drug Synergism; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E, Synthetic; Xanthenes; Xanthones | 1993 |
EP receptor subtypes implicated in the PGE2-induced sensitization of polymodal receptors in response to bradykinin and heat.
Topics: Alprostadil; Animals; Bradykinin; Cyclic AMP; Dinoprostone; Dogs; Hot Temperature; Nociceptors; Prostaglandin Antagonists; Prostaglandins E, Synthetic; Receptors, Prostaglandin E; Xanthenes; Xanthones | 1996 |
A common low-affinity binding site for primary prostanoids on bovine aortic endothelial cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Binding Sites; Biphenyl Compounds; Carbazoles; Cattle; Cells, Cultured; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Endothelium, Vascular; Epoprostenol; Heptanoic Acids; Iloprost; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Sulfonamides; Thromboxane A2; Thromboxanes; Xanthenes; Xanthones | 1996 |
Effects of eicosanoids on parameters in isolated rat hepatocytes and isolated rat hepatocyte couplets: protective effects of eicosanoid receptor antagonists.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cell Membrane; Cells, Cultured; Cholic Acids; Dinoprost; Dinoprostone; Dioxanes; Eicosanoids; Fluoresceins; Liver; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Rats; Receptors, Eicosanoid; Thromboxane A2; Vasoconstrictor Agents; Xanthenes; Xanthones | 1997 |
Modulation of noradrenaline release in rat isolated stomach by prostanoids, but not by histaminergic mechanisms.
Topics: Abortifacient Agents, Nonsteroidal; Animals; Dinoprostone; Electric Stimulation; Female; Gastric Mucosa; Histamine Agonists; Indomethacin; Methylhistamines; Misoprostol; Muscarinic Agonists; Norepinephrine; Oxotremorine; Parasympatholytics; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Histamine; Receptors, Prostaglandin; Scopolamine; Stomach; Tetrodotoxin; Xanthenes; Xanthones; Yohimbine | 1995 |
Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E2 inhibits lipopolysaccharide-induced tumour necrosis factor-alpha generation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biphenyl Compounds; Dinoprostone; Drug Interactions; Epoprostenol; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Prostaglandin Antagonists; Prostaglandin Endoperoxides, Synthetic; Prostanoic Acids; Receptors, Prostaglandin; Thromboxane A2; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1997 |
EP1 receptor blockade attenuates both spontaneous tone and PGE2-elicited contraction in guinea pig trachealis.
Topics: Acetylcholine; Animals; Biphenyl Compounds; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Electric Stimulation; Epithelium; Guinea Pigs; Iloprost; In Vitro Techniques; Indomethacin; Kinetics; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Trachea; Xanthenes; Xanthones | 1997 |
Pharmacological characterization of thromboxane and prostanoid receptors in human isolated urinary bladder.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Biphenyl Compounds; Dinoprost; Dinoprostone; Electric Stimulation; Heptanoic Acids; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Prostaglandin Antagonists; Prostaglandin D2; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Thromboxane; Thromboxane A2; Urinary Bladder; Xanthenes; Xanthones | 1998 |
Responses of guinea-pig lung parenchymal strips to tracheobronchial lavage fluid from horses affected with summer pasture-associated obstructive pulmonary disease.
Topics: Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Dinoprostone; Guinea Pigs; Histamine; Horse Diseases; Horses; In Vitro Techniques; Leukotriene D4; Lung; Lung Diseases, Obstructive; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Poaceae; Prostaglandin Antagonists; Quinolines; Reference Values; Seasons; Trachea; Xanthenes; Xanthones | 1998 |
System A neutral amino acid transporter regulation by interleukin-1beta in human osteoarthritic synovial cells: evidence for involvement of prostaglandin E(2) as a second messenger.
Topics: Amino Acid Transport Systems; Arachidonic Acids; beta-Alanine; Biological Transport; Carrier Proteins; Cells, Cultured; Cyclooxygenase 2; Cytosol; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Indans; Interleukin-1; Isoenzymes; Kinetics; Membrane Proteins; Osteoarthritis; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Second Messenger Systems; Synovial Membrane; Xanthenes; Xanthones | 2000 |
Regulation of the human prostanoid TPalpha and TPbeta receptor isoforms mediated through activation of the EP(1) and IP receptors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biological Transport; Blood Platelets; Calcium; Cells, Cultured; Dinoprostone; Drug Interactions; Enzyme Inhibitors; Epoprostenol; Humans; Indoles; Isoquinolines; Maleimides; Prostaglandin Antagonists; Prostaglandins; Protein Isoforms; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane; Signal Transduction; Sulfonamides; Vasoconstrictor Agents; Xanthenes; Xanthones | 2000 |
Prostaglandin EP receptor subtypes have distinctive effects on jejunal afferent sensitivity in the rat.
Topics: Animals; Calcium Channel Blockers; Dinoprostone; Dose-Response Relationship, Drug; Electrophysiology; Gastrointestinal Motility; Jejunum; Male; Neurons, Afferent; Nifedipine; Prostaglandin Antagonists; Prostaglandins; Protein Isoforms; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Prostaglandin E; Xanthenes; Xanthones | 2000 |
Role of PGE(2) in protease-activated receptor-1, -2 and -4 mediated relaxation in the mouse isolated trachea.
Topics: Animals; Caenorhabditis elegans Proteins; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; In Vitro Techniques; Indomethacin; Isoenzymes; Ligands; Male; Membrane Proteins; Mice; Mice, Inbred CBA; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Receptor, PAR-2; Receptors, Thrombin; Thrombin; Trachea; Trypsin; Xanthenes; Xanthones | 2001 |
EP(4) receptors mediate prostaglandin E(2)-stimulated glycosaminoglycan synthesis in human cervical fibroblasts in culture.
Topics: Alprostadil; Biphenyl Compounds; Cells, Cultured; Cervix Uteri; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Female; Fibroblasts; Glycosaminoglycans; Humans; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Xanthenes; Xanthones | 2001 |
Human granulosa-lutein cells express functional EP1 and EP2 prostaglandin receptors.
Topics: 16,16-Dimethylprostaglandin E2; Alprostadil; Calcium; Cells, Cultured; Cyclic AMP; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Female; Granulosa Cells; Humans; Intracellular Fluid; Lutein; Progesterone; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Xanthenes; Xanthones | 2001 |
Prostanoids stimulate K secretion and Cl secretion in guinea pig distal colon via distinct pathways.
Topics: Animals; Bumetanide; Chlorides; Colon; Cyclooxygenase Inhibitors; Dinoprostone; Diuretics; Dose-Response Relationship, Drug; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Male; Potassium; Prostaglandin Antagonists; Receptors, Prostaglandin; Xanthenes; Xanthones | 2001 |
Prostanoid EP(1)- and TP-receptors involved in the contraction of human pulmonary veins.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biphenyl Compounds; Carbazoles; Culture Techniques; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Iloprost; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandin Antagonists; Prostaglandins F, Synthetic; Pulmonary Veins; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Thromboxane; Sulfonamides; Vasoconstriction; Xanthenes; Xanthones | 2001 |
Role of EP(1) and EP(4) PGE(2) subtype receptors in serum-induced 3T6 fibroblast cycle progression and proliferation.
Topics: Animals; Biphenyl Compounds; Calcium; Cell Cycle; Cell Division; Cells, Cultured; Cyclic AMP; Cyclins; Dinoprostone; Fibroblasts; Mice; Prostaglandin Antagonists; Protein Isoforms; Xanthenes; Xanthones | 2002 |
AH6809 antagonizes non-small cell lung cancer prostaglandin receptors.
Topics: Binding Sites; Calcium; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Membrane; Colony-Forming Units Assay; Cyclic AMP; Cytoplasm; Dinoprostone; DNA Primers; Humans; Lung Neoplasms; Prostaglandin Antagonists; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xanthenes; Xanthones | 2002 |
Effects of PGE2 in guinea pig colonic myenteric ganglia.
Topics: Action Potentials; Animals; Colon; Dinoprostone; Dose-Response Relationship, Drug; Electric Impedance; Electrophysiology; Female; Ganglia; Guinea Pigs; Male; Membrane Potentials; Microelectrodes; Myenteric Plexus; Neurokinin-1 Receptor Antagonists; Neurons; Receptors, Neurokinin-3; Receptors, Prostaglandin; Tetrodotoxin; Xanthenes; Xanthones | 2002 |
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dinoprostone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Guinea Pigs; Hydantoins; Hydrazines; Iloprost; In Vitro Techniques; Intestine, Small; Leukotriene Antagonists; Leukotriene D4; Male; Oxazepines; Peristalsis; Prostaglandin D2; Prostaglandins A; Receptors, Leukotriene; Receptors, Prostaglandin; Xanthenes; Xanthones; Yohimbine | 2002 |
Modulation of guinea pig intrinsic cardiac neurons by prostaglandins.
Topics: Animals; Dinoprostone; Female; Ganglia, Parasympathetic; Guinea Pigs; Heart; Hydantoins; Male; Mast Cells; Membrane Potentials; Phospholipases A; Phospholipases A2; Potassium Channel Blockers; Prostaglandin D2; Receptors, Prostaglandin; Xanthenes; Xanthones | 2003 |
Effects of mechanical strain on the function of Gap junctions in osteocytes are mediated through the prostaglandin EP2 receptor.
Topics: Adenylyl Cyclases; Animals; Blotting, Western; Cell Line; Cells, Cultured; Connexin 43; Culture Media, Conditioned; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Gap Junctions; Isoenzymes; Isoquinolines; Models, Biological; Osteocytes; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stress, Mechanical; Sulfonamides; Time Factors; Xanthones | 2003 |
Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells.
Topics: Alprostadil; Animals; Breast Neoplasms; Carcinoma; Cell Movement; Colforsin; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Indoles; Isoenzymes; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Neoplasm Invasiveness; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Tumor Cells, Cultured; Up-Regulation; Xanthenes; Xanthones | 2003 |
Leukotriene D4-induced adhesion of Caco-2 cells is mediated by prostaglandin E2 and upregulation of alpha2beta1-integrin.
Topics: Caco-2 Cells; Carcinoma; Cell Adhesion; Colitis; Collagen Type I; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Extracellular Matrix; Humans; Integrin alpha2beta1; Isoenzymes; Leukotriene D4; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Receptors, Leukotriene; Sulfonamides; Up-Regulation; Xanthenes; Xanthones | 2003 |
Glutamate-mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytes.
Topics: Animals; Astrocytes; Calcium; Calcium Signaling; Cell Line; Cells, Cultured; Coculture Techniques; Cycloleucine; Cytosol; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Epithelial Cells; Glutamic Acid; Green Fluorescent Proteins; Humans; Indomethacin; Luminescent Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Patch-Clamp Techniques; Prostaglandins; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Transfection; Valine; Xanthones | 2003 |
E-ring 8-isoprostanes inhibit ACh release from parasympathetic nerves innervating guinea-pig trachea through agonism of prostanoid receptors of the EP3-subtype.
Topics: Acetylcholine; Animals; Dinoprostone; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Isoprostanes; Male; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Prostaglandins E, Synthetic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Synaptic Transmission; Trachea; Vas Deferens; Xanthones | 2004 |
Inhibition of human glioma cell growth by a PHS-2 inhibitor, NS398, and a prostaglandin E receptor subtype EP1-selective antagonist, SC51089.
Topics: Animals; Brain Neoplasms; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Glioma; Humans; Hydrazines; Isoenzymes; Membrane Proteins; Mice; Mice, SCID; Nitrobenzenes; Oxazepines; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Sulfonamides; Transplantation, Heterologous; Tumor Cells, Cultured; Xanthones | 2004 |
Identification in human airways smooth muscle cells of the prostanoid receptor and signalling pathway through which PGE2 inhibits the release of GM-CSF.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenoviridae; Adolescent; Adult; Aged; Alprostadil; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Female; Gene Expression; Genetic Vectors; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Interleukin-1; Isoquinolines; Male; Middle Aged; Misoprostol; Myocytes, Smooth Muscle; Prostaglandins E, Synthetic; Protein Isoforms; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Sulfonamides; Trachea; Xanthones | 2004 |
Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia.
Topics: Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression Regulation; Microglia; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Xanthones | 2004 |
Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs.
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Calpain; Cell Line, Tumor; Chondrocytes; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diclofenac; Dinoprostone; Humans; Nitrobenzenes; Phenylpropionates; Prostaglandin Antagonists; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthones | 2004 |
EP1- and EP3-receptors mediate prostaglandin E2-induced constriction of porcine large cerebral arteries.
Topics: Animals; Cells, Cultured; Cerebral Arteries; Dinoprostone; Estrenes; Female; Immunohistochemistry; In Vitro Techniques; Male; Muscle, Smooth; Neomycin; Oxyhemoglobins; Pyrrolidinones; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Swine; Vasoconstriction; Xanthones | 2004 |
Lipopolysaccharide-induced changes in mesenteric afferent sensitivity of rat jejunum in vitro: role of prostaglandins.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; In Vitro Techniques; Jejunum; Lipopolysaccharides; Lymph Nodes; Male; Naproxen; Neurons, Afferent; Prostaglandin Antagonists; Prostaglandins; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Xanthones | 2005 |
Prostaglandin E2 drives cyclooxygenase-2 expression via cyclic AMP response element activation in human pancreatic cancer cells.
Topics: Cell Line, Tumor; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Models, Biological; Pancreatic Neoplasms; Phosphorylation; Prostaglandin Antagonists; Sulfonamides; Xanthones | 2005 |
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC.
Topics: Alprostadil; Atherosclerosis; Cells, Cultured; Dinoprostone; Foam Cells; Humans; Interleukin-10; Isoprostanes; Macrophages; Monocytes; Oxidation-Reduction; Phosphatidylcholines; Phospholipid Ethers; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthones | 2006 |
Involvement of EP1 and EP2 receptors in the regulation of the Na,K-ATPase by prostaglandins in MDCK cells.
Topics: Alprostadil; Animals; Cell Line; Dinoprostone; Dogs; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hydrazines; Ion Transport; Kidney Tubules, Distal; Oxazepines; Prostaglandin Antagonists; Protein Kinase C; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Sodium-Potassium-Exchanging ATPase; Xanthones | 2006 |
Involvement of cyclooxygenase-2--prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells.
Topics: Adenocarcinoma; Arachidonic Acid; Biphenyl Compounds; Cell Line, Tumor; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Fibroblasts; Gene Expression Regulation, Neoplastic; Helicobacter pylori; Humans; Interleukin-8; Nitrobenzenes; Prostaglandin Antagonists; Receptors, Prostaglandin E; RNA, Messenger; Stomach Neoplasms; Sulfonamides; Xanthones | 2006 |
Prostaglandin E2 enhances the sensitizing effect of hyperthermia on pulmonary C-fibers in rats.
Topics: Anesthesia; Animals; Biphenyl Compounds; Body Temperature; Dinoprostone; Fever; In Vitro Techniques; Infusions, Intravenous; Lung; Male; Nerve Fibers, Unmyelinated; Neurons, Afferent; Pneumonia; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Respiration, Artificial; Xanthones | 2007 |
Prostaglandin E2 enhances acetylcholine-induced, Ca2+-dependent ionic currents in swine tracheal mucous gland cells.
Topics: Acetylcholine; Animals; Boron Compounds; Calcium; Calcium Channel Blockers; Carrier Proteins; Cells, Cultured; Charybdotoxin; Colforsin; Dinoprostone; Epithelial Cells; Imidazoles; Ion Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Mucous Membrane; Patch-Clamp Techniques; Peptide Fragments; Peptides; Potassium Channel Blockers; Prostaglandin Antagonists; Swine; Trachea; Xanthones | 2007 |
TNF-alpha modulates hepatic Na+-K+ ATPase activity via PGE2 and EP2 receptors.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Indomethacin; Liver; Male; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Sodium-Potassium-Exchanging ATPase; Tumor Necrosis Factor-alpha; Xanthones | 2007 |
PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11beta-hydroxysteroid dehydrogenase activity by prostaglandin E2 in human granulosa lutein cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Alprostadil; Cells, Cultured; Cortisone; Cyclic AMP; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Luteal Cells; Progesterone; Prostaglandin Antagonists; Prostaglandins E, Synthetic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Xanthones | 2007 |
The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Immunohistochemistry; Naphthalenes; Phenylephrine; Potassium Chloride; Propionates; Prostaglandin Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane; Sulfonamides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Xanthones | 2008 |
Prostaglandin E2 and F2alpha activate the FP receptor and up-regulate cyclooxygenase-2 expression via the cyclic AMP response element.
Topics: Adenocarcinoma; Cell Line, Tumor; Cyclooxygenase 2; Dinoprost; Dinoprostone; Endometrial Neoplasms; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Inositol 1,4,5-Trisphosphate; Promoter Regions, Genetic; Prostaglandin Antagonists; Receptors, Prostaglandin; Receptors, Prostaglandin E; Response Elements; Signal Transduction; Xanthones | 2008 |
The effects of cyclooxygenase2-prostaglandinE2 pathway on Helicobacter pylori-induced urokinase-type plasminogen activator system in the gastric cancer cells.
Topics: Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Helicobacter pylori; Humans; Neoplasm Invasiveness; Receptors, Cell Surface; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Urokinase-Type Plasminogen Activator; Xanthones | 2008 |
Developmental changes in the effects of prostaglandin E2 in the chicken ductus arteriosus.
Topics: Age Factors; Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Cyclic AMP; Dinoprostone; Ductus Arteriosus; Fatty Acids, Unsaturated; Hydrazines; Isoproterenol; Milrinone; Muscle Contraction; Xanthones | 2009 |
Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration.
Topics: Alprostadil; Benzimidazoles; Calcium Channel Agonists; Cell Movement; Chemotaxis; Dinoprostone; Histamine Release; Humans; Mast Cells; Potassium Channels; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Xanthones | 2008 |
Effect of prostaglandin E2 on urokinase-type plasminogen activator production by human lung fibroblasts.
Topics: Base Sequence; Biphenyl Compounds; Dinoprostone; DNA Primers; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Lung; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urokinase-Type Plasminogen Activator; Xanthones | 2009 |
Ketamine inhibits the phagocytic responses of canine peripheral blood polymorphonuclear cells through the upregulation of prostaglandin E2 in peripheral blood mononuclear cells in vitro.
Topics: Animals; Cells, Cultured; Dinoprostone; Dogs; Ketamine; Neutrophils; Phagocytosis; Prostaglandin Antagonists; Up-Regulation; Xanthones | 2009 |
Prostaglandin E2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis.
Topics: Aggrecans; Ankle Joint; Biphenyl Compounds; Cartilage, Articular; Cell Proliferation; Cell Survival; Cells, Cultured; Chondrocytes; Collagen Type I; Collagen Type II; Dinoprostone; Drug Synergism; Gene Expression; Homeostasis; Humans; Interleukin-1; Middle Aged; Osteoarthritis, Knee; Phosphatidylinositol 3-Kinases; Proteoglycans; Receptors, Prostaglandin E; Signal Transduction; Synovial Fluid; Xanthones | 2009 |
Roles of cyclooxygenase-2 in microvascular endothelial cell proliferation induced by basic fibroblast growth factor.
Topics: Blotting, Western; Cell Line; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2; Humans; Receptors, Prostaglandin E; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A; Xanthones | 2008 |
Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Diabetes Mellitus; Dinoprostone; Disease Models, Animal; Hypertension; Male; Mice; Mice, Mutant Strains; Muscle, Skeletal; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Vascular Resistance; Vasoconstrictor Agents; Xanthones | 2009 |
Prostaglandin E2 released from activated microglia enhances astrocyte proliferation in vitro.
Topics: Animals; Astrocytes; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Prostaglandin Antagonists; Rats; Rats, Inbred F344; Thiophenes; Xanthones | 2009 |
Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo.
Topics: Animals; Benzofurans; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Fatty Acids, Unsaturated; Flurbiprofen; Glutamic Acid; Glutamine; Glycine; Hydrazines; Isoprostanes; Neurotransmitter Agents; Nitrobenzenes; Prostaglandins; Receptors, Prostaglandin; Retina; Sulfonamides; Xanthones | 2009 |
Prostaglandin E2 signaling through E prostanoid receptor 2 impairs proliferative response of double negative regulatory T cells.
Topics: Alprostadil; Animals; CD4 Antigens; CD8 Antigens; Cell Proliferation; Clone Cells; Cytotoxicity, Immunologic; Dinoprostone; Immunomagnetic Separation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prostaglandin Antagonists; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; T-Lymphocytes, Regulatory; Xanthones | 2009 |
Expression of cyclooxygenase-1/-2, microsomal prostaglandin-E synthase-1 and E-prostanoid receptor 2 and regulation of inflammatory mediators by PGE(2) in the amoeboid microglia in hypoxic postnatal rats and murine BV-2 cells.
Topics: Animals; Animals, Newborn; CD11b Antigen; Cell Line; Cell Movement; Cell Survival; Cyclic AMP; Cytokines; Dinoprostone; Disease Models, Animal; Encephalitis; Hypoxia, Brain; Intramolecular Oxidoreductases; Mice; Microglia; Microsomes; Nitric Oxide Synthase Type II; Prostaglandin Antagonists; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Signal Transduction; Xanthones | 2009 |
Prostaglandin E2 mediates cough via the EP3 receptor: implications for future disease therapy.
Topics: Animals; Benzofurans; Cough; Cyclopentanes; Dimethyl Sulfoxide; Dinoprostone; Guinea Pigs; Humans; In Vitro Techniques; Isoindoles; Male; Mice; Mice, Inbred C57BL; Propionates; Pyridines; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Sensory Receptor Cells; Sulfonamides; Vagus Nerve; Xanthones | 2009 |
Human papillomavirus type 16 E5 protein inhibits hydrogen-peroxide-induced apoptosis by stimulating ubiquitin-proteasome-mediated degradation of Bax in human cervical cancer cells.
Topics: Androstadienes; Apoptosis; bcl-2-Associated X Protein; Biphenyl Compounds; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Humans; Hydrogen Peroxide; Isoquinolines; Neoplasm Proteins; Oncogene Proteins, Viral; Proteasome Endopeptidase Complex; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Small Interfering; Sulfonamides; Ubiquitin; Uterine Cervical Neoplasms; Wortmannin; Xanthones | 2010 |
Inducible cyclooxygenase released prostaglandin E2 modulates the severity of infection caused by Streptococcus pyogenes.
Topics: Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Female; Host-Pathogen Interactions; Humans; Immunohistochemistry; Macrophages; Mice; Mice, Inbred C3H; Mice, Knockout; Nitrobenzenes; Prostaglandin Antagonists; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Severity of Illness Index; Streptococcal Infections; Streptococcus pyogenes; Sulfonamides; Xanthones | 2010 |
Functional and molecular characterization of prostaglandin E2 dilatory receptors in the rat craniovascular system in relevance to migraine.
Topics: Adenine; Alprostadil; Animals; Cerebral Arteries; Dinoprostone; Enzyme Inhibitors; Male; Meningeal Arteries; Migraine Disorders; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Trigeminal Nerve; Vasodilation; Xanthones | 2010 |
Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Cell Line; Chemokine CCL5; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Interferon-gamma; Interleukin-2; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrobenzenes; Prostaglandin Antagonists; Protein Kinase Inhibitors; Shock, Septic; Signal Transduction; Sulfonamides; Tumor Escape; Xanthones | 2011 |
EP4 receptor as a new target for bronchodilator therapy.
Topics: Alprostadil; Animals; Asthma; Bridged Bicyclo Compounds, Heterocyclic; Bronchodilator Agents; Dinoprostone; Fatty Acids, Unsaturated; Guinea Pigs; Humans; Hydrazines; Macaca fascicularis; Methyl Ethers; Mice; Mice, Inbred C57BL; Naphthalenes; Phenylbutyrates; Prostanoic Acids; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Regression Analysis; Species Specificity; Trachea; Xanthones | 2011 |
Prostaglandin E2 induces spontaneous rhythmic activity in mouse urinary bladder independently of efferent nerves.
Topics: Animals; Benzenesulfonates; Calcium; Dinoprostone; Female; In Vitro Techniques; Mice; Muscle Contraction; Muscle, Smooth; Neurons, Efferent; Prostaglandin Antagonists; Purinergic P2X Receptor Antagonists; Sodium Channel Blockers; Tetrodotoxin; Urinary Bladder; Xanthones | 2012 |
The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination.
Topics: Animals; Apoptosis; Caspase 3; Cattle; Celecoxib; Chelating Agents; Cuprizone; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Demyelinating Diseases; Dinoprostone; Fluorescent Antibody Technique; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Sheath; Oligodendroglia; Postural Balance; Pyrazoles; Real-Time Polymerase Chain Reaction; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Sulfonamides; Xanthones | 2012 |
Suppressive effect of aqueous humor on lipopolysaccharide-induced dendritic cell maturation.
Topics: Animals; Antibodies, Neutralizing; Aqueous Humor; B7-1 Antigen; B7-2 Antigen; Cells, Cultured; Dendritic Cells; Dextrans; Dinoprostone; Down-Regulation; Endocytosis; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescein-5-isothiocyanate; Histocompatibility Antigens Class II; Lipopolysaccharides; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Prostaglandin Antagonists; Swine; T-Lymphocytes; Transforming Growth Factor beta2; Xanthones | 2011 |
Thromboxane and isoprostane share the same prostanoid receptors to increase human placental tone.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Bridged Bicyclo Compounds, Heterocyclic; Dinoprostone; Dioxanes; Fatty Acids, Unsaturated; Female; Humans; Hydrazines; In Vitro Techniques; Isoprostanes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Placenta; Pregnancy; Prostaglandins; Receptors, Prostaglandin E; Receptors, Thromboxane A2, Prostaglandin H2; Thromboxanes; Xanthones | 2011 |
PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment.
Topics: Biphenyl Compounds; CD11b Antigen; Celecoxib; Cell Movement; Cells, Cultured; Chemokine CXCL12; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Monocytes; Myeloid Cells; Ovarian Neoplasms; Prostaglandin Antagonists; Pyrazoles; Receptors, CXCR4; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides; Tumor Cells, Cultured; Tumor Microenvironment; Xanthones | 2011 |
Involvement of COX-2/PGE2 signalling in hypoxia-induced angiogenic response in endothelial cells.
Topics: Aquaporin 1; Cell Hypoxia; Cell Movement; Cell Proliferation; Cell Shape; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Neovascularization, Physiologic; Nitrobenzenes; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors; Transcription, Genetic; Vascular Endothelial Growth Factor A; Xanthones | 2012 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Influenza A virus; Isoproterenol; Leukocytes; Male; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Orthomyxoviridae Infections; Piperidines; Prostaglandin Antagonists; Respiratory Mucosa; Specific Pathogen-Free Organisms; Substance P; Trachea; TRPV Cation Channels; Xanthones | 2012 |
Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling.
Topics: Animals; Antigens, Differentiation; CD11b Antigen; Cell Line, Tumor; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Female; Flow Cytometry; Gene Expression; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Misoprostol; Peritonitis; Prostaglandin Antagonists; Receptor, Macrophage Colony-Stimulating Factor; Receptors, Prostaglandin E, EP2 Subtype; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thioglycolates; Xanthones | 2012 |
Prostaglandin E2 blocks menadione-induced apoptosis through the Ras/Raf/Erk signaling pathway in promonocytic leukemia cell lines.
Topics: Apoptosis; Cell Survival; Cell Transformation, Neoplastic; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Isoquinolines; Lamin Type B; Leukemia; Lipid Peroxidation; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Receptors, Prostaglandin E, EP2 Subtype; Sulfonamides; Vitamin K 3; Xanthones | 2012 |
Murine corneal stroma cells suppress bone marrow-derived dendritic cells maturation in vitro.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Corneal Stroma; Culture Media, Conditioned; Dendritic Cells; Dimethyl Sulfoxide; Dinoprostone; Flow Cytometry; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Transforming Growth Factor beta2; Xanthones | 2012 |
Role of hypoxia-inducible factor 1, α subunit and cAMP-response element binding protein 1 in synergistic release of interleukin 8 by prostaglandin E2 and nickel in lung fibroblasts.
Topics: Alprostadil; Biomimetics; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dinoprostone; Drug Synergism; Fibroblasts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-8; Lung; Nickel; p38 Mitogen-Activated Protein Kinases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Xanthones | 2013 |
Coculture with endothelial cells enhances osteogenic differentiation of periodontal ligament stem cells via cyclooxygenase-2/prostaglandin E2/vascular endothelial growth factor signaling under hypoxia.
Topics: Angiogenesis Inhibitors; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endothelial Cells; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Nitrobenzenes; Osteogenesis; Periodontal Ligament; Prostaglandin Antagonists; Protein Kinase Inhibitors; Pyrroles; Signal Transduction; Stem Cells; Sulfonamides; Thiophenes; Triazoles; Vascular Endothelial Growth Factor A; Xanthones | 2013 |
Increased saturated fatty acids in obesity alter resolution of inflammation in part by stimulating prostaglandin production.
Topics: Animals; Apoptosis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Fatty Acids; Humans; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neutrophils; Obesity; Palmitic Acid; Peritonitis; Phagocytosis; Prostaglandin D2; Receptors, Prostaglandin; Receptors, Prostaglandin E, EP2 Subtype; Xanthones | 2013 |
Cyclooxygenase-2, prostaglandin E2 glycerol ester and nitric oxide are involved in muscarine-induced presynaptic enhancement at the vertebrate neuromuscular junction.
Topics: Animals; Arachidonic Acids; Benzoates; Capsaicin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endocannabinoids; Glycerides; Imidazoles; Lizards; Miniature Postsynaptic Potentials; Muscarine; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Schwann Cells; Sulfonamides; Thiophenes; Xanthones | 2013 |
Coordinated induction of cyclooxygenase-2/prostaglandin E2 and hepatocyte growth factor by apoptotic cells prevents lung fibrosis.
Topics: Animals; Apoptosis; Bleomycin; Cyclooxygenase 2; Dinoprostone; Hepatocyte Growth Factor; Indoles; Male; Mice; Mice, Inbred C57BL; Nitrobenzenes; Pulmonary Fibrosis; Signal Transduction; Sulfonamides; Sulfones; Xanthones | 2013 |
Regulation of rat intrapulmonary arterial tone by arachidonic acid and prostaglandin E2 during hypoxia.
Topics: Animals; Arachidonic Acid; Calcium; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Hypoxia; Male; Muscle Tonus; Oxytocics; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Prostaglandin E; Thiophenes; Triazoles; Vasoconstriction; Xanthones | 2013 |
Silymarin suppresses the PGE2 -induced cell migration through inhibition of EP2 activation; G protein-dependent PKA-CREB and G protein-independent Src-STAT3 signal pathways.
Topics: Alprostadil; Antioxidants; Benzodioxoles; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; HCT116 Cells; HT29 Cells; Humans; Integrases; Kidney Neoplasms; Phosphorylation; Prostaglandin Antagonists; Quinazolines; Receptors, Prostaglandin E, EP2 Subtype; RNA Interference; RNA, Small Interfering; Signal Transduction; Silymarin; src-Family Kinases; STAT3 Transcription Factor; Wound Healing; Xanthones | 2015 |
PAR1-dependent COX-2/PGE2 production contributes to cell proliferation via EP2 receptors in primary human cardiomyocytes.
Topics: Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Humans; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NF-kappa B; Receptor, PAR-1; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Thrombin; Transcription Factor AP-1; Xanthones | 2014 |
Prostaglandin potentiates 5-HT responses in stomach and ileum innervating visceral afferent sensory neurons.
Topics: Animals; Anti-Inflammatory Agents; Carbazoles; Dinoprostone; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Ileum; Male; Neurons, Afferent; Nodose Ganglion; Ondansetron; Patch-Clamp Techniques; Prostaglandins; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Sensory Receptor Cells; Serotonin; Signal Transduction; Stomach; Thiophenes; Triazoles; Visceral Afferents; Xanthones | 2015 |
Lipopolysaccharide induces inflammation and facilitates lung metastasis in a breast cancer model via the prostaglandin E2-EP2 pathway.
Topics: Animals; Blood Vessels; Breast Neoplasms; Celecoxib; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Endothelial Cells; Female; Inflammation; Lipopolysaccharides; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Receptors, Prostaglandin E; Vascular Endothelial Growth Factor A; Xanthones | 2015 |
Prostaglandin E2 blockade enhances the pulmonary anti-Cryptococcus neoformans immune reaction via the induction of TLR-4.
Topics: Animals; Cryptococcosis; Cryptococcus neoformans; Cytokines; Dinoprostone; Lung; Macrophages, Alveolar; Mice, Inbred BALB C; Mice, Knockout; Prostaglandin Antagonists; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Toll-Like Receptor 4; Xanthones | 2015 |
Oxytocin evokes a pulsatile PGE2 release from ileum mucosa and is required for repair of intestinal epithelium after injury.
Topics: Animals; Antineoplastic Agents; Calcium; Cyclooxygenase 2; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Evoked Potentials; Fluorouracil; Ileum; Immunohistochemistry; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Ions; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Neoplasms; Oxytocin; Rats; Rats, Wistar; Receptors, Oxytocin; Wound Healing; Xanthones | 2015 |
Prostanoids regulate angiogenesis acting primarily on IP and EP4 receptors.
Topics: Benzyl Compounds; Cell Movement; Dinoprostone; Endothelial Cells; Epoprostenol; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Neovascularization, Pathologic; Neovascularization, Physiologic; Prostaglandins I; Real-Time Polymerase Chain Reaction; Receptors, Epoprostenol; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles; Xanthones | 2015 |
Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality.
Topics: Animals; Arachidonate 5-Lipoxygenase; Blotting, Western; Carrier Proteins; Celecoxib; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dinoprostone; In Vitro Techniques; Indoles; Indomethacin; Inflammasomes; Interleukin-1beta; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Macrophages, Peritoneal; Mice; Mice, Knockout; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphoproteins; Prostaglandin Antagonists; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Reverse Transcriptase Polymerase Chain Reaction; Scorpion Stings; Scorpion Venoms; Scorpions; Xanthones | 2016 |
[Media of rat macrophage NR8383 cells with prostaglandins E2-induced VEGF over-expression promotes migration and tube formation of human umbilical vein endothelial cells].
Topics: Animals; Cell Line; Cell Movement; Cells, Cultured; Culture Media, Conditioned; Dinoprostone; Human Umbilical Vein Endothelial Cells; Humans; Macrophages; Neovascularization, Pathologic; Rats; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Vascular Endothelial Growth Factor A; Xanthones | 2016 |
PTGER2 activation induces PTGS-2 and growth factor gene expression in endometrial epithelial cells of cattle.
Topics: Alprostadil; Animals; Cattle; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Endometrium; Epithelial Cells; Female; Gene Expression Regulation; Intercellular Signaling Peptides and Proteins; Interleukin-8; MAP Kinase Signaling System; Prostaglandin Antagonists; Receptors, Prostaglandin E, EP2 Subtype; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Xanthones | 2017 |
The protective effect of the EP2 receptor on TGF-β1 induced podocyte injury via the PI3K / Akt signaling pathway.
Topics: Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Cytoskeletal Proteins; Dinoprostone; Gene Expression Regulation; Mice; Phosphatidylinositol 3-Kinases; Podocytes; Proto-Oncogene Proteins c-akt; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Transforming Growth Factor beta1; Xanthones | 2018 |
AH6809 decreases production of inflammatory mediators by PGE
Topics: Animals; Brain Concussion; CA1 Region, Hippocampal; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Hippocampus; Inflammation; Interleukin-1beta; Lipopolysaccharides; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Xanthones | 2018 |
Prostaglandin E2 facilitates Hepatitis B virus replication by impairing CTL function.
Topics: Animals; CD8-Positive T-Lymphocytes; Dinoprostone; Hep G2 Cells; Hepatitis B virus; Hepatitis B, Chronic; Host-Pathogen Interactions; Humans; Mice, Inbred C57BL; Perforin; Prostaglandin Antagonists; T-Lymphocytes, Cytotoxic; Viral Load; Virus Replication; Xanthones | 2018 |
Cyclooxygenase 2 Promotes Proliferation and Invasion in Ovarian Cancer Cells via the PGE2/NF-κB Pathway.
Topics: Animals; Antineoplastic Agents; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Humans; Mice, Nude; Neoplasm Grading; Neoplasm Invasiveness; NF-kappa B; Nitriles; Ovarian Neoplasms; Phosphorylation; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Sulfones; Transplantation, Heterologous; Xanthones | 2019 |
Mechanism of Na-K-ATPase Inhibition by PGE2 in Intestinal Epithelial Cells.
Topics: Animals; Cell Line; Cell Survival; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Epithelial Cells; Intestines; Intracellular Space; Protein Subunits; Rats; Receptors, Prostaglandin; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Xanthones | 2021 |
Proliferation of bovine endometrial epithelial cells is promoted by prostaglandin E
Topics: Alprostadil; Aminopyridines; Animals; Cattle; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinases; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endometrium; Epithelial Cells; Female; Proliferating Cell Nuclear Antigen; Purines; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Up-Regulation; Xanthones | 2021 |