Envenomation, Scorpion

Synonym
Scorpion Envenoming
Envenomation, Scorpion
Scorpion Stings
Scorpionism

Excerpt	Reference
"The majority of scorpion stings are oligosymptomatic, occurring mainly on the hands and feet."	( de Freitas Filho, O; de Freitas, DG; Garcia, AS, 1999)
"Though scorpion envenomation is known to lead to acute myocarditis and a reversible decrease in left ventricular function, it has not been implicated as an etiological factor in idiopathic dilated cardiomyopathy."	( Narayan, KA; Olithselvan, M; Sethuraman, KR; Sundararaman, T, 1999)
"In Mexico, scorpion envenomation is considered a public health problem."	( Jiménez-Ferrer, JE; Pérez-Terán, YY; Román-Ramos, R; Tortoriello, J, 2005)
"Death caused by scorpion envenoming is a common event in the tropical and subtropical countries including many regions in India."	( Deodhar, KP; Murthy, RK; Natu, VS, 2006)
"The scorpion envenomation is considered the second event by poisonous animals in importance around the world according to the World Health Organization."	( Izquierdo, LM; Rodríguez Buitrago, JR, 2012)
"Scorpion stings are common in many regions of the world, particularly in rural areas."	( Al, B; Kilic, H; Oktay, MM; Zengin, S, 2012)
"Tityus scorpion stings are an important public health problem in Brazil, where the incidence of such stings exceeds the incidence of the health problems caused by other venomous animals, including snakes."	( Carvalho, DC; Kuniyoshi, AK; Pidde-Queiroz, G; Portaro, FC; Tambourgi, DV; Venancio, EJ, 2013)
"Serum K in scorpionism is the net result of the two opposing effects."	( Angsanakul, J; Sitprija, V, 2013)
"Severe scorpion envenomation is rare, which makes treatment difficult to study using conventional controlled clinical trials; and small-scale placebo-controlled trials conducted in tertiary centers are of limited generalizability to the community setting."	( Alagón, A; Berg, M; Boyer, LV; Carbajal, Y; Chase, PB; de Jesus-Hernandez, T; Mallie, J; Olvera, F; Osnaya, N; Theodorou, AA, 2013)
"The incidence of scorpion envenomation is not negligible despite underreporting of cases, most often treated in traditional medicine."	( Baldé, H; Baldé, O; Bangoura, EF; Djessanglar, R; Sako, FB; Soumah, MM; Tounkara, TM; Traoré, FA, 2014)
"Scorpion envenoming is a frequent and deadly event in Tunisia."	( Bahloul, M; Ben Hamida, C; Bouaziz, M; Chelly, H; Kallel, H, 2020)
"Scorpionism is responsible for most accidents involving venomous animals in Brazil, which leads to severe symptoms that can evolve to death."	( Abreu, CB; Alexandre-Silva, GM; Arantes, EC; Balenzuela, C; Bordon, KCF; Cerni, FA; Cunha, TM; Faccioli, LH; Oliveira, IS; Peigneur, S; Pinheiro-Júnior, EL; Pucca, MB; Quinton, L; Reis, MB; Tytgat, J; Wiezel, GA; Zoccal, KF; Zottich, U, 2020)

Excerpt	Reference
"Current management of human scorpionism consists of early admission to hospital and immediate reduction of raised blood pressure with sublingual nifedipine while peripheral action of venom is antagonized by the post-synaptic alpha blocker prazosin; in addition, digoxin, frusemide, aminophylline and oxygen are administered."	( Bawaskar, HS; Bawaskar, PH, 1991)
"Passive immunotherapy against scorpion envenomations is facilitated by the preliminary titration of circulating toxins in envenomed patients."	( Aubrey, N; Billiald, P; Devaux, C, 2002)
"To study outcome of patients with scorpion envenomation treated with oral captopril in the ICU of a Tertiary Care, University Hospital in Mumbai."	( Karnad, DR; Krishnan, A; Sonawane, RV, 2007)
"Severe scorpion envenomation is rare, which makes treatment difficult to study using conventional controlled clinical trials; and small-scale placebo-controlled trials conducted in tertiary centers are of limited generalizability to the community setting."	( Alagón, A; Berg, M; Boyer, LV; Carbajal, Y; Chase, PB; de Jesus-Hernandez, T; Mallie, J; Olvera, F; Osnaya, N; Theodorou, AA, 2013)
"Treatment of pulmonary edema due to scorpion envenomation follows the same principles as those applied for the treatment of cardiogenic pulmonary edema in general: this begins with oxygen supplementation targeting an oxygen saturation of 92% or more, by oxygen mask, continuous positive airway pressure, noninvasive ventilation, or conventional mechanical ventilation."	( Abroug, F; Dachraoui, F; Fekih-Hassen, M; Ouanes Besbes, L; Ouanes, I; Souheil, E, 2015)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	30 (18.07)	23.3326
1990's	36 (21.69)	12.5806
2000's	43 (25.90)	18.1394
2010's	46 (27.71)	28.8240
2020's	11 (6.63)	9.53

Drug	Relationship Strength	Studies	Trials
histamine	low	1	0
methanol	low	1	0
acetaminophen	medium	3	3
acetazolamide	low	1	0
antazoline	low	1	0
aristolochic acid i	low	1	0
celecoxib	low	1	0
doxazosin	low	1	0
fentanyl	low	1	0
furosemide	low	3	0
glutaral	low	1	0
hydralazine	low	1	0
lidocaine	medium	5	3
indomethacin	low	1	0
meperidine	low	1	0
mepivacaine	low	1	0
midazolam	medium	4	1
nifedipine	medium	5	1
nitroglycerin	low	1	0
phenobarbital	low	1	0
prazosin	medium	38	6
propranolol	low	1	0
ticlopidine	low	1	0
aldosterone	low	2	0
p-aminoazobenzene	low	1	0
mannitol	low	1	0
methylprednisolone	low	1	0
calcium gluconate	low	1	0
emetine	low	4	0
methamphetamine	low	4	0
acetylcysteine	low	1	0
technetium	low	1	0
magnesium sulfate	low	1	0
aluminum sulfate	low	1	0
dobutamine	medium	12	1
captopril	low	4	0
clopidogrel	low	1	0
glucuronic acid	low	1	0
fluorocitrate	low	1	0
deoxyglucose	low	1	0
ah 6809	low	1	0
arginylarginine	low	1	0
leucylarginine	low	1	0
angiotensin ii	medium	2	1
atropine	low	5	0
dexketoprofen trometamol	medium	1	1
bq 123	low	1	0
squalene	low	1	0
buprenorphine	low	1	0
dieldrin	low	1	0
l 663536	low	1	0
bilirubin	low	1	0
dinoprostone	low	3	0
leukotriene b4	low	2	0
thallium	low	1	0
beta-escin	low	1	0
mocetinostat	low	1	0
scopolamine hydrobromide	low	1	0
ants	low	4	0
a 803467	low	1	0
neuropeptide y	low	1	0
endothelin-1	low	3	0
cortisol succinate, sodium salt	medium	1	1
piperidines	low	1	0
interleukin-8	low	2	0
natriuretic peptide, brain	low	2	0
minocycline	low	1	0
charybdotoxin	low	1	0
pyrethrins	low	1	0
scorpion toxin i, androctonus	low	2	0
hyaluronoglucosaminidase	low	3	0

Protein Targets (842)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
cytochrome P450 family 3 subfamily A polypeptide 4	17	0	0	17
EWS/FLI fusion protein	13	0	0	13
G	11	0	0	11
cytochrome P450 2D6	8	0	0	8
Potassium voltage-gated channel subfamily KQT member 3	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 2	0	1	0	1
Interferon beta	15	0	0	15
HLA class I histocompatibility antigen, B alpha chain	11	0	0	11
Muscarinic acetylcholine receptor M2	0	5	2	11
Muscarinic acetylcholine receptor M4	0	5	1	9
5-hydroxytryptamine receptor 1A	0	3	0	3
Muscarinic acetylcholine receptor M5	0	4	1	8
Alpha-2A adrenergic receptor	0	9	3	14
Adenosine receptor A3	0	6	1	7
Muscarinic acetylcholine receptor M1	0	6	2	12
D(2) dopamine receptor	0	3	1	4
Alpha-2B adrenergic receptor	0	10	1	13
Muscarinic acetylcholine receptor M3	0	5	2	10
Cannabinoid receptor 1	0	1	0	1
D(1A) dopamine receptor	0	4	1	5
D(4) dopamine receptor	0	3	0	3
D(1B) dopamine receptor	0	1	0	1
Histamine H2 receptor	0	2	2	4
C-X-C chemokine receptor type 2	0	1	0	1
Endothelin-1 receptor	0	4	1	6
Adenosine receptor A1	0	1	0	1
5-hydroxytryptamine receptor 1B	0	4	1	5
5-hydroxytryptamine receptor 2A	0	3	1	4
5-hydroxytryptamine receptor 2C	0	9	1	10
Adenosine receptor A2a	0	3	1	4
Translocator protein	0	2	0	2
Adenosine receptor A1	0	3	0	3
Cholecystokinin receptor type A	0	2	1	3
C-C chemokine receptor type 1	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	1	3
Cannabinoid receptor 2	0	1	0	1
Histamine H1 receptor	0	6	2	8
Alpha-1B adrenergic receptor	0	4	2	10
Mu-type opioid receptor	0	7	4	12
D(3) dopamine receptor	0	5	0	5
Delta-type opioid receptor	0	7	2	10
Kappa-type opioid receptor	0	8	2	11
Nociceptin receptor	0	1	0	1
P2Y purinoceptor 2	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 6	0	3	1	4
P2X purinoceptor 3	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	16	0	16
Sodium channel protein type 5 subunit alpha	0	4	0	4
Sodium channel protein type 9 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Inositol hexakisphosphate kinase 1	11	0	0	11
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	11	0	11
Sodium channel protein type 3 subunit alpha	0	4	0	4
P2X purinoceptor 2	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	2	0	2
cytochrome P450 2C9, partial	11	0	0	11
RAR-related orphan receptor gamma	14	0	0	14
ATAD5 protein, partial	9	0	0	9
GLS protein	8	0	0	8
Microtubule-associated protein tau	12	0	0	12
Smad3	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	11	0	0	11
thyroid stimulating hormone receptor	7	0	0	7
nuclear receptor subfamily 1, group I, member 3	11	0	0	11
progesterone receptor	12	0	0	12
retinoic acid nuclear receptor alpha variant 1	12	0	0	12
retinoid X nuclear receptor alpha	13	0	0	13
estrogen-related nuclear receptor alpha	14	0	0	14
estrogen nuclear receptor alpha	24	0	0	24
peroxisome proliferator activated receptor gamma	12	0	0	12
aryl hydrocarbon receptor	7	0	0	7
chromobox protein homolog 1	10	0	0	10
thyroid hormone receptor beta isoform 2	18	0	0	18
peripheral myelin protein 22	9	0	0	9
cytochrome P450 3A4 isoform 1	9	0	0	9
Gamma-aminobutyric acid receptor subunit pi	9	6	2	17
ATP-binding cassette sub-family C member 3	0	16	0	16
Multidrug resistance-associated protein 4	0	16	0	17
Solute carrier family 22 member 6	0	5	0	5
Carbonic anhydrase 12	0	6	1	11
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	5	0	5
Voltage-dependent calcium channel gamma-2 subunit	9	0	0	9
Bile salt export pump	0	28	0	28
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	7	1	14
Carbonic anhydrase 2	0	7	1	14
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	3	0	4
Prostaglandin G/H synthase 1	0	5	0	6
Carbonic anhydrase 3	0	6	1	10
Cytochrome P450 3A4	0	10	2	12
Cytochrome P450 2D6	0	6	0	6
Cytochrome P450 2C9	0	8	0	8
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	9	6	2	17
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	9	6	2	17
Gamma-aminobutyric acid receptor subunit gamma-2	9	6	2	17
UDP-glucuronosyltransferase 1-6	0	1	0	2
Glutamate receptor 2	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-5	9	6	2	17
Gamma-aminobutyric acid receptor subunit alpha-3	9	6	2	17
Arachidonate 5-lipoxygenase-activating protein	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	1	0	2
Carbonic anhydrase 4	0	6	1	10
Prostaglandin G/H synthase 1	0	4	0	5
Carbonic anhydrase 6	0	6	1	10
Gamma-aminobutyric acid receptor subunit gamma-1	9	6	2	17
Gamma-aminobutyric acid receptor subunit alpha-2	9	6	2	17
Gamma-aminobutyric acid receptor subunit alpha-4	9	6	2	17
Gamma-aminobutyric acid receptor subunit gamma-3	9	6	2	17
Gamma-aminobutyric acid receptor subunit alpha-6	9	6	2	17
Carbonic anhydrase 5A, mitochondrial	0	6	1	11
Prostaglandin G/H synthase 2	0	6	2	10
Carbonic anhydrase 7	0	6	1	10
Nuclear receptor ROR-gamma	6	1	1	8
Cytochrome P450 2J2	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	9	7	2	18
Gamma-aminobutyric acid receptor subunit beta-3	9	6	2	17
Gamma-aminobutyric acid receptor subunit beta-2	9	6	2	17
Carbonic anhydrase 9	0	7	1	12
GABA theta subunit	9	6	2	17
Canalicular multispecific organic anion transporter 1	0	14	0	14
Carbonic anhydrase 15	0	4	0	6
Carbonic anhydrase 13	0	4	0	7
Gamma-aminobutyric acid receptor subunit epsilon	9	6	2	17
Carbonic anhydrase 14	0	6	1	11
Carbonic anhydrase 5B, mitochondrial	0	6	1	11
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	5	0	0	5
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	5	0	0	5
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
thioredoxin reductase	10	0	0	10
GALC protein	3	0	0	3
GLI family zinc finger 3	15	0	0	15
glucocorticoid receptor [Homo sapiens]	20	0	0	20
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
arylsulfatase A	5	0	0	5
Carbonic anhydrase	0	2	0	2
euchromatic histone-lysine N-methyltransferase 2	18	0	0	18
Bloom syndrome protein isoform 1	4	0	0	4
thyroid hormone receptor beta isoform a	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	13	0	0	13
geminin	17	0	0	17
survival motor neuron protein isoform d	5	0	0	5
muscleblind-like protein 1 isoform 1	4	0	0	4
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	3	0	3
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Cytochrome P450 2C8	0	4	0	4
Cytochrome P450 2A6	0	1	0	1
5-hydroxytryptamine receptor 2A	0	4	0	4
Androgen receptor	0	6	0	6
Translocator protein	0	3	2	6
Cannabinoid receptor 1	0	1	0	1
Cytochrome P450 2B6	0	4	0	4
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	3	0	4
Serum paraoxonase/arylesterase 1	0	3	0	3
Dipeptidyl peptidase 4	0	0	0	1
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	3	0	4
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium-dependent serotonin transporter	0	3	1	4
Delta-type opioid receptor	0	6	0	7
Cytochrome P450 2C19	0	6	0	6
Delta-type opioid receptor	0	7	1	9
Mu-type opioid receptor	0	6	2	11
Carbonic anhydrase	0	2	0	3
Kappa-type opioid receptor	0	6	0	6
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	2	1	0	3
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	0	2
Carbonic anhydrase	0	2	0	4
D(2) dopamine receptor	0	4	0	4
Cholinesterase	0	1	0	1
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	9	1	10
Fatty-acid amide hydrolase 1	0	1	0	1
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	1	0	2
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	3	0	3
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	4
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	4	1	7
Carbonic anhydrase 4	0	4	0	5
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
acetylcholinesterase	7	0	0	7
dopamine D1 receptor	2	0	0	2
15-lipoxygenase, partial	4	0	0	4
pregnane X receptor	5	0	0	5
phosphopantetheinyl transferase	7	0	0	7
USP1 protein, partial	14	0	0	14
NFKB1 protein, partial	2	0	0	2
Thrombopoietin	4	0	0	4
AR protein	26	0	0	26
regulator of G-protein signaling 4	5	0	0	5
farnesoid X nuclear receptor	11	0	0	11
vitamin D (1,25- dihydroxyvitamin D3) receptor	12	0	0	12
D(1A) dopamine receptor	5	0	0	5
heat shock protein beta-1	7	0	0	7
flap endonuclease 1	4	0	0	4
muscarinic acetylcholine receptor M1	4	0	0	4
Histone deacetylase 3	0	4	0	4
Histone deacetylase 4	0	3	0	3
Guanine nucleotide-binding protein G	3	0	0	3
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	3	0	3
Ataxin-2	15	0	0	15
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	3	0	3
ATP-dependent phosphofructokinase	5	0	0	5
Chain A, HADH2 protein	6	0	0	6
Chain B, HADH2 protein	6	0	0	6
cellular tumor antigen p53 isoform a	6	0	0	6
cytochrome P450 2C9 precursor	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
lethal factor (plasmid)	6	0	0	6
Prostaglandin E2 receptor EP1 subtype	0	3	1	4
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin E2 receptor EP3 subtype	0	3	1	4
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Prostacyclin receptor	0	3	1	4
Histamine H2 receptor	6	0	1	8
Prostaglandin D2 receptor	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	1	2	3
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	2
glucocerebrosidase	3	0	0	3
DNA polymerase kappa isoform 1	6	0	0	6
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
TDP1 protein	21	0	0	21
cytochrome P450 2D6 isoform 1	5	0	0	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
lamin isoform A-delta10	14	0	0	14
Histamine H1 receptor	0	1	3	4
Inositol monophosphatase 1	3	0	0	3
Solute carrier family 15 member 1	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
glp-1 receptor, partial	5	0	0	5
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
nuclear receptor ROR-gamma isoform 1	9	0	0	9
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Cyclin-dependent kinase 2	0	1	0	1
pregnane X nuclear receptor	11	0	0	11
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	2	0	0	2
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	8	0	10
5-hydroxytryptamine receptor 4	0	8	0	8
Muscarinic acetylcholine receptor M1	0	5	1	8
Muscarinic acetylcholine receptor M3	0	4	1	7
Muscarinic acetylcholine receptor M4	0	4	1	7
Muscarinic acetylcholine receptor M5	0	4	1	7
Muscarinic acetylcholine receptor M2	0	5	2	10
Muscarinic acetylcholine receptor M1	0	0	0	1
Alpha-1D adrenergic receptor	0	8	2	14
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 7	0	4	0	4
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	2
Chain A, Cruzipain	5	0	0	5
vitamin D3 receptor isoform VDRA	6	0	0	6
caspase-1 isoform alpha precursor	1	0	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1B3	0	5	0	6
Solute carrier organic anion transporter family member 1B1	0	6	0	7
Solute carrier organic anion transporter family member 1A4	0	1	0	3
Multidrug resistance-associated protein 6	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Endothelin receptor type B	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	2
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
thioredoxin glutathione reductase	2	0	0	2
Metallo-beta-lactamase type 2	0	1	1	2
peripheral myelin protein 22 isoform 1	3	0	0	3
M-phase phosphoprotein 8	3	0	0	3
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Prothrombin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	3	1	4
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	2	1	3
Angiotensin-converting enzyme	0	6	0	7
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	1
TAR DNA-binding protein 43	2	0	0	2
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	1	1	2
Beta-lactamase class B VIM-2	0	1	1	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
SMAD family member 2	5	0	0	5
PPM1D protein	5	0	0	5
SMAD family member 3	5	0	0	5
caspase 7, apoptosis-related cysteine protease	3	0	0	3
estrogen receptor 2 (ER beta)	10	0	0	10
67.9K protein	6	0	0	6
peroxisome proliferator-activated receptor delta	7	0	0	7
Rac1 protein	0	0	1	1
caspase-3	3	0	0	3
IDH1	7	0	0	7
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	13	0	0	13
thyroid stimulating hormone receptor	7	0	0	7
activating transcription factor 6	9	0	0	9
thyrotropin-releasing hormone receptor	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
Histone H2A.x	5	0	0	5
Caspase-7	2	0	0	2
interferon gamma precursor	0	0	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
caspase-3	2	0	0	2
Prostaglandin E synthase	0	3	0	3
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	3
Prostaglandin G/H synthase 2	0	2	0	3
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	2	0	2
Cellular tumor antigen p53	16	0	0	16
Procathepsin L	0	2	1	3
Aldo-keto reductase family 1 member B1	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	3	0	3
Quinolone resistance protein NorA	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	3	0	3
Beta-3 adrenergic receptor	0	4	1	5
Alpha-1B adrenergic receptor	0	8	2	10
Calpain-2 catalytic subunit	0	1	0	1
5-hydroxytryptamine receptor 1A	0	6	2	9
Prostaglandin G/H synthase 1	0	2	0	2
Sodium-dependent noradrenaline transporter	0	4	1	5
Cruzipain	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Sodium-dependent serotonin transporter	0	10	1	11
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Alpha-1A adrenergic receptor	0	9	3	12
Urotensin-2 receptor	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	4	0	4
Sodium-dependent dopamine transporter	0	6	0	6
Prostaglandin G/H synthase 2	0	2	0	3
Mitogen-activated protein kinase 14	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
ATPase family AAA domain-containing protein 5	10	0	0	10
P2Y purinoceptor 12	0	2	0	2
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
MBT domain-containing protein 1	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
nonstructural protein 1	3	0	0	3
Liver carboxylesterase 1	0	0	0	2
P2Y purinoceptor 12	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
Rap guanine nucleotide exchange factor 3	1	0	0	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Fatty acid-binding protein, liver	0	1	0	1
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	2	4	7
Albumin	0	0	1	1
ATP-dependent translocase ABCB1	0	9	0	13
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Fumarate hydratase	4	0	0	4
polyprotein	4	0	0	4
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	8	0	0	8
interleukin 8	3	0	0	3
PAX8	0	0	0	1
STAT3, partial	0	1	0	1
alpha-galactosidase	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
tumor necrosis factor	2	0	0	2
ras-related protein Rab-9A	6	0	0	6
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Integrin beta-3	5	0	0	5
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Integrin alpha-IIb	5	0	0	5
Replicase polyprotein 1ab	0	2	2	4
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
mitogen-activated protein kinase 1	5	0	0	5
Solute carrier family 22 member 2	0	1	0	3
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier family 22 member 6	0	1	0	2
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
Spike glycoprotein	9	0	1	10
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
mu-type opioid receptor isoform MOR-1	0	0	1	1
huntingtin isoform 2	2	0	0	2
5-hydroxytryptamine receptor 2A	0	0	1	1
Epidermal growth factor receptor	0	2	0	2
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Beta-2 adrenergic receptor	0	6	1	7
Beta-1 adrenergic receptor	0	4	1	5
POU domain, class 2, transcription factor 1	0	0	0	1
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
Alpha-1A adrenergic receptor	0	2	1	3
Interstitial collagenase	0	2	0	2
Alpha-1A adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	8	2	12
Alpha-2B adrenergic receptor	0	2	2	4
Alpha-2C adrenergic receptor	0	2	2	4
Alpha-2A adrenergic receptor	0	2	2	4
Alpha-1D adrenergic receptor	0	4	2	6
Alpha-1A adrenergic receptor	0	4	3	13
Alpha-synuclein	1	0	0	1
5-hydroxytryptamine receptor 2B	0	6	1	7
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
NS5	0	0	1	1
Parkin	4	0	0	4
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Glucose transporter	0	1	0	1
Serine hydrolase RBBP9	0	1	0	1
Hexose transporter 1	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	2
Dihydroorotate dehydrogenase	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	2
Luciferase	7	0	0	7
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Kappa-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	4	1	7
Sigma non-opioid intracellular receptor 1	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
Multidrug and toxin extrusion protein 1	0	4	0	4
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	4
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
apical membrane antigen 1, AMA1	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
transforming acidic coiled-coil-containing protein 3	0	0	0	1
DNA polymerase iota isoform a (long)	4	0	0	4
Solute carrier family 22 member 3	0	2	0	3
Plasma kallikrein	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
5-hydroxytryptamine receptor 1D	0	1	0	2
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Histamine H3 receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Equilibrative nucleoside transporter 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	2	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
Histamine H3 receptor	0	1	2	3
pyruvate kinase	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Lactoperoxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
neuropeptide S receptor isoform A	2	0	0	2
Prostaglandin-H2 D-isomerase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Androgen receptor	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	4
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Thromboxane-A synthase	0	2	0	2
Caspase-1	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	1
Substance-P receptor	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
tyrosine-protein kinase Yes	1	0	0	1
streptokinase A precursor	0	0	1	1
Estrogen receptor	0	0	1	1
Leukotriene C4 synthase	0	1	0	1
Macrophage-expressed gene 1 protein	0	1	0	1
Estrogen receptor beta	0	0	1	1
Leukotriene C4 synthase	0	0	0	1
Prostaglandin E synthase 2	0	1	0	1
Leukotriene B4 receptor 1	0	2	0	3
Leukotriene B4 receptor 2	0	1	0	2
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 2	0	1	1	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Kappa-type opioid receptor	0	3	1	5
Solute carrier family 22 member 3	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Glucocorticoid receptor	0	2	0	2
Glycine receptor subunit alpha-1	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Stromelysin-1	0	1	0	1
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Protein-arginine deiminase type-4	0	2	0	2
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	2	1	5
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Atrial natriuretic peptide receptor 1	0	1	0	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
hypothetical protein, conserved	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
cytochrome P450 2C19 precursor	2	0	0	2
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Phospholipase A2, membrane associated	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
C-C chemokine receptor type 2	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Potassium channel subfamily K member 2	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Chain A, Ferritin light chain	3	0	0	3
acid sphingomyelinase	1	0	0	1
histone deacetylase 9 isoform 3	2	0	0	2
pyruvate kinase PKM isoform a	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
Beta-casein	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
D	0	1	0	1
Alpha-mannosidase 2C1	0	0	1	1
Bromodomain-containing protein 2	0	2	0	2
5-hydroxytryptamine receptor 1B	0	3	0	3
5-hydroxytryptamine receptor 1D	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Beta-1 adrenergic receptor	0	1	1	3
Beta-2 adrenergic receptor	0	2	0	3
Beta-1 adrenergic receptor	0	2	1	4
D(3) dopamine receptor	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Beta-1 adrenergic receptor	0	1	0	1
Vasopressin V1a receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Squalene monooxygenase	0	0	0	1
Cytochrome P450 3A5	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (166)

Protein Targets (842)

Envenomation, Scorpion

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (166)

Drugs Studied (91)

Protein Targets (842)