fleroxacin has been researched along with Chancroid in 4 studies
Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.
Chancroid: Acute, localized autoinoculable infectious disease usually acquired through sexual contact. Caused by HAEMOPHILUS DUCREYI, it occurs endemically almost worldwide, especially in tropical and subtropical countries and more commonly in seaports and urban areas than in rural areas.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In Kenya, researchers enrolled 53, men aged 18-60 years with chancroid who enrolled at the Nairobi City Council Special Treatment Clinic in a clinical trial to test the efficacy of fleroxacin in clinical Haemophilus ducreyi infections." | 9.06 | Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya. ( Cameron, DW; D'Costa, L; MacDonald, KS; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1989) |
| "Fleroxacin was prescribed to treat both HIV-negative and HIV-positive men with proven chancroid in an open study." | 7.68 | Fleroxacin in the treatment of chancroid: an open study in men seropositive or seronegative for the human immunodeficiency virus type 1. ( Agoki, E; Malisa, W; Ndinya-Achola, JO; Plourde, PJ; Plummer, FA; Ronald, AR; Tyndall, MW, 1993) |
| "Chancroid is linked to the spread of human immunodeficiency virus type 1 (HIV-1) in East Africa." | 6.67 | A randomized, double-blind study of the efficacy of fleroxacin versus trimethoprim-sulfamethoxazole in men with culture-proven chancroid. ( Agoki, E; D'Costa, LJ; Ndinya-Achola, JO; Ombette, J; Plourde, PJ; Plummer, FA; Ronald, AR; Slaney, LA, 1992) |
| "In Kenya, researchers enrolled 53, men aged 18-60 years with chancroid who enrolled at the Nairobi City Council Special Treatment Clinic in a clinical trial to test the efficacy of fleroxacin in clinical Haemophilus ducreyi infections." | 5.06 | Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya. ( Cameron, DW; D'Costa, L; MacDonald, KS; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1989) |
| "Fleroxacin was prescribed to treat both HIV-negative and HIV-positive men with proven chancroid in an open study." | 3.68 | Fleroxacin in the treatment of chancroid: an open study in men seropositive or seronegative for the human immunodeficiency virus type 1. ( Agoki, E; Malisa, W; Ndinya-Achola, JO; Plourde, PJ; Plummer, FA; Ronald, AR; Tyndall, MW, 1993) |
| "Chancroid is linked to the spread of human immunodeficiency virus type 1 (HIV-1) in East Africa." | 2.67 | A randomized, double-blind study of the efficacy of fleroxacin versus trimethoprim-sulfamethoxazole in men with culture-proven chancroid. ( Agoki, E; D'Costa, LJ; Ndinya-Achola, JO; Ombette, J; Plourde, PJ; Plummer, FA; Ronald, AR; Slaney, LA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mutua, FM | 1 |
| M'imunya, JM | 1 |
| Wiysonge, CS | 1 |
| Tyndall, MW | 1 |
| Plourde, PJ | 2 |
| Agoki, E | 2 |
| Malisa, W | 1 |
| Ndinya-Achola, JO | 3 |
| Plummer, FA | 3 |
| Ronald, AR | 3 |
| D'Costa, LJ | 1 |
| Ombette, J | 1 |
| Slaney, LA | 1 |
| MacDonald, KS | 1 |
| Cameron, DW | 1 |
| D'Costa, L | 1 |
1 review available for fleroxacin and Chancroid
| Article | Year |
|---|---|
Genital ulcer disease treatment for reducing sexual acquisition of HIV.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Chancroid; Female; Fleroxacin; HIV Infec | 2012 |
2 trials available for fleroxacin and Chancroid
| Article | Year |
|---|---|
A randomized, double-blind study of the efficacy of fleroxacin versus trimethoprim-sulfamethoxazole in men with culture-proven chancroid.
Topics: Administration, Oral; Adult; Chancroid; Double-Blind Method; Fleroxacin; Follow-Up Studies; Humans; | 1992 |
Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; | 1989 |
1 other study available for fleroxacin and Chancroid
| Article | Year |
|---|---|
Fleroxacin in the treatment of chancroid: an open study in men seropositive or seronegative for the human immunodeficiency virus type 1.
Topics: Administration, Oral; Adolescent; Adult; Aged; Analysis of Variance; Chancroid; Fleroxacin; Haemophi | 1993 |