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ciprofloxacin and Chancroid

ciprofloxacin has been researched along with Chancroid in 17 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Chancroid: Acute, localized autoinoculable infectious disease usually acquired through sexual contact. Caused by HAEMOPHILUS DUCREYI, it occurs endemically almost worldwide, especially in tropical and subtropical countries and more commonly in seaports and urban areas than in rural areas.

Research Excerpts

ExcerptRelevanceReference
"A randomized, double-blind, placebo-controlled clinical trial was conducted in Nairobi, Kenya, to compare single-dose ciprofloxacin with a 7-day course of erythromycin for the treatment of chancroid."9.09A randomized, double-blind, placebo-controlled trial of single-dose ciprofloxacin versus erythromycin for the treatment of chancroid in Nairobi, Kenya. ( MacDonald, KS; Maclean, I; Malonza, IM; Moses, S; Ndinya-Achola, JO; Omar, S; Orle, K; Perriens, J; Plummer, FA; Ronald, AR; Tyndall, MW, 1999)
"Ciprofloxacin and erythromycin are equally effective in chancroid."9.08A comparative study of therapeutic response of patients with clinical chancroid to ciprofloxacin, erythromycin, and cotrimoxazole. ( D'Souza, P; Khanna, N; Misra, RS; Pandhi, RK; Rattan, A, 1998)
"In Kenya, researchers enrolled 53, men aged 18-60 years with chancroid who enrolled at the Nairobi City Council Special Treatment Clinic in a clinical trial to test the efficacy of fleroxacin in clinical Haemophilus ducreyi infections."9.06Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya. ( Cameron, DW; D'Costa, L; MacDonald, KS; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1989)
"A single dose therapy of 500 mg ciprofloxacin was sufficient to cure 15 of 18 chancroid patients within six days and the remaining three within 7, 11 and 20 days respectively."9.06Efficacy and safety of a single dose therapy of a 500 mg ciprofloxacin tablet in chancroid patients. ( Tesavibul, P; Traisupa, A; Wongba, C, 1988)
"A randomized, double-blind study was performed comparing ciprofloxacin in a 500-mg single dose with 1,000 mg (500-mg doses given 12 h apart) for the treatment of chancroid in Thailand."9.06Evaluation of 500- and 1,000-mg doses of ciprofloxacin for the treatment of chancroid. ( Bodhidatta, L; Chitwarakorn, A; Echeverria, P; Kuvanont, K; Taylor, DN, 1988)
"Ciprofloxacin is a new quinolone antimicrobial agent with excellent in vitro efficacy against H."6.66Treatment of chancroid with ciprofloxacin. A prospective, randomized clinical trial. ( D'Costa, LJ; Greenblatt, RM; Naamara, W; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1987)
"A randomized, double-blind, placebo-controlled clinical trial was conducted in Nairobi, Kenya, to compare single-dose ciprofloxacin with a 7-day course of erythromycin for the treatment of chancroid."5.09A randomized, double-blind, placebo-controlled trial of single-dose ciprofloxacin versus erythromycin for the treatment of chancroid in Nairobi, Kenya. ( MacDonald, KS; Maclean, I; Malonza, IM; Moses, S; Ndinya-Achola, JO; Omar, S; Orle, K; Perriens, J; Plummer, FA; Ronald, AR; Tyndall, MW, 1999)
"A comparative open study was performed to evaluate the efficacy of single doses of ciprofloxacin (500 mg) and trimethoprim-sulfamethoxazole (TMP-SMZ; 640 mg/3,200 mg) for the treatment of culture-proven chancroid."5.08Failure of treatment for chancroid in Rwanda is not related to human immunodeficiency virus infection: in vitro resistance of Haemophilus ducreyi to trimethoprim-sulfamethoxazole. ( Akingeneye, J; Bogaerts, J; Kestens, L; Martinez Tello, W; Mukantabana, V; Piot, P; Van Dyck, E; Verhaegen, J, 1995)
"Ciprofloxacin and erythromycin are equally effective in chancroid."5.08A comparative study of therapeutic response of patients with clinical chancroid to ciprofloxacin, erythromycin, and cotrimoxazole. ( D'Souza, P; Khanna, N; Misra, RS; Pandhi, RK; Rattan, A, 1998)
"In Kenya, researchers enrolled 53, men aged 18-60 years with chancroid who enrolled at the Nairobi City Council Special Treatment Clinic in a clinical trial to test the efficacy of fleroxacin in clinical Haemophilus ducreyi infections."5.06Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya. ( Cameron, DW; D'Costa, L; MacDonald, KS; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1989)
" Treatment failure rates for culture-proven chancroid were 19% for trimethoprim-sulfamethoxazole, 12."3.69Sexually transmitted diseases and human immunodeficiency virus control in Malawi: a field study of genital ulcer disease. ( Behets, FM; Cohen, MS; Dallabetta, G; Hamilton, HA; Hoffman, IF; Liomba, G; Lule, G; Moeng, S, 1995)
"Ciprofloxacin is a new quinolone antimicrobial agent with excellent in vitro efficacy against H."2.66Treatment of chancroid with ciprofloxacin. A prospective, randomized clinical trial. ( D'Costa, LJ; Greenblatt, RM; Naamara, W; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1987)
"Treatment with ciprofloxacin for the diagnosis of H."1.48Haemophilus ducreyi cutaneous ulcer contracted at Seram Island, Indonesia, presented in the Netherlands. ( Bruisten, SM; de Bree, GJ; de Vries, HJC; Grobusch, MP; Kolader, M; Langeveld, TJC; van Hattem, JM, 2018)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's10 (58.82)18.2507
2000's1 (5.88)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Hattem, JM1
Langeveld, TJC1
Bruisten, SM1
Kolader, M1
Grobusch, MP1
de Vries, HJC1
de Bree, GJ1
Trombley, MP1
Post, DM1
Rinker, SD1
Reinders, LM1
Fortney, KR1
Zwickl, BW1
Janowicz, DM1
Baye, FM1
Katz, BP1
Spinola, SM2
Bauer, ME1
Bogaerts, J1
Kestens, L1
Martinez Tello, W1
Akingeneye, J1
Mukantabana, V1
Verhaegen, J1
Van Dyck, E1
Piot, P1
Behets, FM1
Liomba, G1
Lule, G1
Dallabetta, G1
Hoffman, IF1
Hamilton, HA1
Moeng, S1
Cohen, MS1
Ismaeel, NA1
Abeck, D1
Ballard, RC1
Thornton, AC1
O'Mara, EM1
Sorensen, SJ1
Hiltke, TJ1
Fortney, K1
Katz, B1
Shoup, RE1
Hood, AF1
D'Souza, P1
Pandhi, RK1
Khanna, N1
Rattan, A1
Misra, RS1
Malonza, IM1
Tyndall, MW1
Ndinya-Achola, JO3
Maclean, I1
Omar, S1
MacDonald, KS2
Perriens, J1
Orle, K1
Plummer, FA3
Ronald, AR3
Moses, S1
Lewis, DA1
Oduor, DO1
Bwayo, JJ1
Bhatt, SM1
Kwasa, TO1
Maitha, GM1
Ombette, JO1
Cameron, DW1
D'Costa, L1
Traisupa, A1
Wongba, C1
Tesavibul, P1
Bodhidatta, L1
Taylor, DN1
Chitwarakorn, A1
Kuvanont, K1
Echeverria, P1
Naamara, W1
Greenblatt, RM1
D'Costa, LJ1

Reviews

1 review available for ciprofloxacin and Chancroid

ArticleYear
Chancroid.
    Current problems in dermatology, 1996, Volume: 24

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ceftriaxone; Cephalosporins; Chancroid;

1996

Trials

8 trials available for ciprofloxacin and Chancroid

ArticleYear
Failure of treatment for chancroid in Rwanda is not related to human immunodeficiency virus infection: in vitro resistance of Haemophilus ducreyi to trimethoprim-sulfamethoxazole.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 20, Issue:4

    Topics: Adult; CD4 Lymphocyte Count; Chancroid; Ciprofloxacin; Drug Resistance, Microbial; Female; Follow-Up

1995
Prevention of experimental Haemophilus ducreyi infection: a randomized, controlled clinical trial.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Chancroid; Ciprofloxacin; Double-

1998
A comparative study of therapeutic response of patients with clinical chancroid to ciprofloxacin, erythromycin, and cotrimoxazole.
    Sexually transmitted diseases, 1998, Volume: 25, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Chancroid; Cipr

1998
A randomized, double-blind, placebo-controlled trial of single-dose ciprofloxacin versus erythromycin for the treatment of chancroid in Nairobi, Kenya.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Chancroid; Ciprofloxacin; Dou

1999
Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents;

1989
Efficacy and safety of a single dose therapy of a 500 mg ciprofloxacin tablet in chancroid patients.
    Infection, 1988, Volume: 16 Suppl 1

    Topics: Administration, Oral; Adult; Chancroid; Ciprofloxacin; Clinical Trials as Topic; Humans; Male; Thail

1988
Evaluation of 500- and 1,000-mg doses of ciprofloxacin for the treatment of chancroid.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5

    Topics: Adult; Chancroid; Ciprofloxacin; Clinical Trials as Topic; Double-Blind Method; Drug Administration

1988
Treatment of chancroid with ciprofloxacin. A prospective, randomized clinical trial.
    The American journal of medicine, 1987, Apr-27, Volume: 82, Issue:4A

    Topics: Adolescent; Adult; Chancroid; Ciprofloxacin; Clinical Trials as Topic; Double-Blind Method; Drug Com

1987

Other Studies

8 other studies available for ciprofloxacin and Chancroid

ArticleYear
Haemophilus ducreyi cutaneous ulcer contracted at Seram Island, Indonesia, presented in the Netherlands.
    PLoS neglected tropical diseases, 2018, Volume: 12, Issue:4

    Topics: Chancroid; Ciprofloxacin; Haemophilus ducreyi; Humans; Indonesia; Male; Netherlands; Skin Ulcer; Tra

2018
Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Administration, Oral; Adult; alpha-Defensins; Anti-Bacterial Agents; Antimicrobial Cationic Peptides

2015
Sexually transmitted diseases and human immunodeficiency virus control in Malawi: a field study of genital ulcer disease.
    The Journal of infectious diseases, 1995, Volume: 171, Issue:2

    Topics: Chancroid; Ciprofloxacin; Erythromycin; Genital Diseases, Male; HIV Infections; Humans; Malawi; Male

1995
In vitro susceptibility of Haemophilus ducreyi to several antibiotics.
    Microbios, 1993, Volume: 74, Issue:299

    Topics: Anti-Bacterial Agents; Ceftriaxone; Chancroid; Ciprofloxacin; Erythromycin; Haemophilus ducreyi; Hum

1993
National guideline for the management of chancroid. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).
    Sexually transmitted infections, 1999, Volume: 75 Suppl 1

    Topics: Anti-Bacterial Agents; Azithromycin; Breast Feeding; Ceftriaxone; Chancroid; Ciprofloxacin; Contrain

1999
Update on the experimental human model for chancroid infection.
    International journal of STD & AIDS, 2000, Volume: 11, Issue:1

    Topics: Animals; Anti-Infective Agents; CD4 Lymphocyte Count; Chancroid; Ciprofloxacin; Disease Models, Anim

2000
Chancroid and TMP-SMX.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:1

    Topics: Anti-Infective Agents; Chancroid; Ciprofloxacin; HIV Infections; Humans; Trimethoprim, Sulfamethoxaz

1996
Multiple sexually acquired diseases occurring concurrently in an HIV positive man: case report, diagnosis and management.
    East African medical journal, 1992, Volume: 69, Issue:6

    Topics: Adult; Anti-Infective Agents; Chancroid; Ciprofloxacin; Condylomata Acuminata; Gonorrhea; HIV Seropo

1992