trimethoprim has been researched along with Chancroid in 37 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Chancroid: Acute, localized autoinoculable infectious disease usually acquired through sexual contact. Caused by HAEMOPHILUS DUCREYI, it occurs endemically almost worldwide, especially in tropical and subtropical countries and more commonly in seaports and urban areas than in rural areas.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred and thirty six patients with chancroid were treated with four different treatment regimens; (A) Sulphaphenazole 1 g 12 hourly by mouth x 10 days (B) Inj streptomycin 1 g intramuscularly daily with sulphaphenazole 1 g 12 hourly orally x 10 days; (C) trimethoprim 200 mg 12 hourly by mouth x 7-10 days, and (D) erythromycin 500 mg 6 hourly orally x 7-10 days." | 9.06 | Sulphaphenazole, streptomycin and sulphaphenazole combination, trimethoprim, and erythromycin in the treatment of chancroid. ( Bakaya, V; Kumar, B; Sharma, VK, 1990) |
| "We conducted a randomized double-blind trial comparing a single dose of trimethoprim-sulfametrole (640 to 3200 mg) with five-day regimens of either trimethoprim-sulfametrole (160 to 800 mg twice daily) or trimethoprim alone (200 mg twice daily) for the treatment of men with chancroid." | 9.05 | Single-dose therapy of chancroid with trimethoprim-sulfametrole. ( D'Costa, LJ; Ellison, RH; Karasira, P; Maclean, IW; Nsanze, H; Plummer, FA; Ronald, AR, 1983) |
| "Since sulphonamides are no longer predictably effective in the treatment of chancroid the combination of trimethoprim-sulphamethoxazole (TMP-SMX) was evaluated to identify other effective regimens." | 9.05 | Treatment of chancroid. A comparison of sulphamethoxazole and trimethoprim-sulphamethoxazole. ( D'Costa, LJ; Fast, MV; MacLean, IW; Nsanze, H; Plummer, FA; Ronald, AR, 1983) |
| "Thirty-five men with chancroid were randomly treated with oral sulfisoxazole, sulfisoxazole and tetracycline, sulfamethoxazole-trimethoprim, or intramuscular streptomycin." | 9.05 | Treatment of chancroid. Comparison of sulfamethoxazole-trimethoprim with recommended therapies. ( Fitzpatrick, JE; Gramstad, ND; Tyler, H, 1981) |
| "A single dose of ceftriaxone (250 mg) administered intramuscularly was compared with trimethoprim-sulfamethoxazole (TMP-SMZ; 160/800 mg) administered orally twice daily for seven days or with a single dose of TMP-SMZ (640/3,200 mg) administered orally for the treatment of chancroid in men in Thailand." | 7.67 | Comparative study of ceftriaxone and trimethoprim-sulfamethoxazole for the treatment of chancroid in Thailand. ( Echeverria, P; Panikabutra, K; Pitarangsi, C; Suvongse, C; Taylor, DN, 1985) |
| "Enoxacin has excellent in vitro activity against H ducreyi, and a randomised clinical trial of three doses of enoxacin 400 mg at intervals of 12 hours compared with a single dose of trimethoprim/sulphametrole (TMP/SMT) 640/3200 mg was therefore conducted." | 6.66 | Treating chancroid with enoxacin. ( D'Costa, LJ; Kunimoto, DY; Naamara, W; Ndinya-Achola, JO; Nsanze, H; Plummer, FA; Ronald, AR, 1988) |
| "Ciprofloxacin is a new quinolone antimicrobial agent with excellent in vitro efficacy against H." | 6.66 | Treatment of chancroid with ciprofloxacin. A prospective, randomized clinical trial. ( D'Costa, LJ; Greenblatt, RM; Naamara, W; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1987) |
| "One hundred and thirty six patients with chancroid were treated with four different treatment regimens; (A) Sulphaphenazole 1 g 12 hourly by mouth x 10 days (B) Inj streptomycin 1 g intramuscularly daily with sulphaphenazole 1 g 12 hourly orally x 10 days; (C) trimethoprim 200 mg 12 hourly by mouth x 7-10 days, and (D) erythromycin 500 mg 6 hourly orally x 7-10 days." | 5.06 | Sulphaphenazole, streptomycin and sulphaphenazole combination, trimethoprim, and erythromycin in the treatment of chancroid. ( Bakaya, V; Kumar, B; Sharma, VK, 1990) |
| "We conducted a randomized double-blind trial comparing a single dose of trimethoprim-sulfametrole (640 to 3200 mg) with five-day regimens of either trimethoprim-sulfametrole (160 to 800 mg twice daily) or trimethoprim alone (200 mg twice daily) for the treatment of men with chancroid." | 5.05 | Single-dose therapy of chancroid with trimethoprim-sulfametrole. ( D'Costa, LJ; Ellison, RH; Karasira, P; Maclean, IW; Nsanze, H; Plummer, FA; Ronald, AR, 1983) |
| "Since sulphonamides are no longer predictably effective in the treatment of chancroid the combination of trimethoprim-sulphamethoxazole (TMP-SMX) was evaluated to identify other effective regimens." | 5.05 | Treatment of chancroid. A comparison of sulphamethoxazole and trimethoprim-sulphamethoxazole. ( D'Costa, LJ; Fast, MV; MacLean, IW; Nsanze, H; Plummer, FA; Ronald, AR, 1983) |
| "Thirty-five men with chancroid were randomly treated with oral sulfisoxazole, sulfisoxazole and tetracycline, sulfamethoxazole-trimethoprim, or intramuscular streptomycin." | 5.05 | Treatment of chancroid. Comparison of sulfamethoxazole-trimethoprim with recommended therapies. ( Fitzpatrick, JE; Gramstad, ND; Tyler, H, 1981) |
| "Since the treatment of chancroid was reviewed in 1982, the results of subsequent treatment trials have offered the clinician additional therapeutic choices as well as shorter courses of therapy." | 3.76 | The treatment of chancroid. ( Schmid, GP, 1986) |
| " Treatment failure rates for culture-proven chancroid were 19% for trimethoprim-sulfamethoxazole, 12." | 3.69 | Sexually transmitted diseases and human immunodeficiency virus control in Malawi: a field study of genital ulcer disease. ( Behets, FM; Cohen, MS; Dallabetta, G; Hamilton, HA; Hoffman, IF; Liomba, G; Lule, G; Moeng, S, 1995) |
| "A single dose of ceftriaxone (250 mg) administered intramuscularly was compared with trimethoprim-sulfamethoxazole (TMP-SMZ; 160/800 mg) administered orally twice daily for seven days or with a single dose of TMP-SMZ (640/3,200 mg) administered orally for the treatment of chancroid in men in Thailand." | 3.67 | Comparative study of ceftriaxone and trimethoprim-sulfamethoxazole for the treatment of chancroid in Thailand. ( Echeverria, P; Panikabutra, K; Pitarangsi, C; Suvongse, C; Taylor, DN, 1985) |
| "Enoxacin has excellent in vitro activity against H ducreyi, and a randomised clinical trial of three doses of enoxacin 400 mg at intervals of 12 hours compared with a single dose of trimethoprim/sulphametrole (TMP/SMT) 640/3200 mg was therefore conducted." | 2.66 | Treating chancroid with enoxacin. ( D'Costa, LJ; Kunimoto, DY; Naamara, W; Ndinya-Achola, JO; Nsanze, H; Plummer, FA; Ronald, AR, 1988) |
| "Ciprofloxacin is a new quinolone antimicrobial agent with excellent in vitro efficacy against H." | 2.66 | Treatment of chancroid with ciprofloxacin. A prospective, randomized clinical trial. ( D'Costa, LJ; Greenblatt, RM; Naamara, W; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1987) |
| "Treatment with sulfamethoxazole trimethopin or streptomycin prevents complications and cures the affection in one or two weeks." | 1.26 | [Reappearance of soft chancre: comments on the current epidemic in Paris (author's transl)]. ( Belaich, S; Bonvalet, D; Broissin, M; Civatte, J; Vallet, C, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (89.19) | 18.7374 |
| 1990's | 3 (8.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mutua, FM | 1 |
| M'imunya, JM | 1 |
| Wiysonge, CS | 1 |
| Jørgensen, J | 1 |
| Menné, T | 1 |
| Plummer, FA | 4 |
| Nsanze, H | 4 |
| D'Costa, LJ | 4 |
| Karasira, P | 1 |
| Maclean, IW | 2 |
| Ellison, RH | 1 |
| Ronald, AR | 4 |
| Fast, MV | 1 |
| Falk, ES | 1 |
| Vorland, LH | 1 |
| Bjorvatn, B | 1 |
| Webster, DR | 1 |
| Paton, DM | 1 |
| Felman, YM | 1 |
| Nikitas, JA | 1 |
| Fitzpatrick, JE | 1 |
| Tyler, H | 1 |
| Gramstad, ND | 1 |
| Meheus, A | 1 |
| Ursi, JP | 1 |
| Van Dyck, E | 1 |
| Ballard, R | 1 |
| Morel, P | 2 |
| Casin, I | 1 |
| Gandiol, C | 1 |
| Vallet, C | 2 |
| Civatte, J | 2 |
| Belaich, S | 1 |
| Bonvalet, D | 1 |
| Broissin, M | 1 |
| Behets, FM | 1 |
| Liomba, G | 1 |
| Lule, G | 1 |
| Dallabetta, G | 1 |
| Hoffman, IF | 1 |
| Hamilton, HA | 1 |
| Moeng, S | 1 |
| Cohen, MS | 1 |
| Ismaeel, NA | 1 |
| Jarisch, R | 1 |
| Bardach, H | 1 |
| Poitschek, C | 1 |
| Rajan, VS | 1 |
| Pang, R | 1 |
| Nayyar, KC | 1 |
| Stolz, E | 1 |
| Michel, MF | 1 |
| Marchand, JP | 1 |
| Strobel, M | 1 |
| N'diaye, B | 1 |
| Renault-Steens, C | 1 |
| Niang, M | 1 |
| Cross, AB | 1 |
| Harris, JR | 1 |
| Kumar, B | 1 |
| Sharma, VK | 1 |
| Bakaya, V | 1 |
| Ballard, RC | 1 |
| Duncan, MO | 1 |
| Fehler, HG | 1 |
| Dangor, Y | 1 |
| Exposto, FL | 1 |
| Latif, AS | 1 |
| Blackmore, CA | 1 |
| Limpakarnjanarat, K | 1 |
| Rigau-Pérez, JG | 1 |
| Albritton, WL | 1 |
| Greenwood, JR | 1 |
| Naamara, W | 2 |
| Kunimoto, DY | 1 |
| Ndinya-Achola, JO | 2 |
| Orellana-Díaz, O | 1 |
| Hernández-Pérez, E | 1 |
| Schmid, GP | 1 |
| Greenblatt, RM | 1 |
| Heise, H | 1 |
| Fiumara, NJ | 1 |
| Rothman, K | 1 |
| Tang, S | 1 |
| Dylewski, J | 1 |
| D'Costa, L | 1 |
| Slaney, L | 1 |
| Ronald, A | 1 |
| Taylor, DN | 1 |
| Pitarangsi, C | 1 |
| Echeverria, P | 1 |
| Panikabutra, K | 1 |
| Suvongse, C | 1 |
| Hoth, I | 1 |
| Bandemir, B | 1 |
| Ahmed, MA | 1 |
| Bell, DR | 1 |
| Stamps, TJ | 1 |
2 reviews available for trimethoprim and Chancroid
| Article | Year |
|---|---|
Genital ulcer disease treatment for reducing sexual acquisition of HIV.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Chancroid; Female; Fleroxacin; HIV Infec | 2012 |
The treatment of chancroid.
Topics: Amoxicillin; Anti-Bacterial Agents; Ceftriaxone; Chancroid; Clavulanic Acid; Clavulanic Acids; Clini | 1986 |
10 trials available for trimethoprim and Chancroid
| Article | Year |
|---|---|
Single-dose therapy of chancroid with trimethoprim-sulfametrole.
Topics: Adult; Chancroid; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Resistance, | 1983 |
Treatment of chancroid. A comparison of sulphamethoxazole and trimethoprim-sulphamethoxazole.
Topics: Adolescent; Adult; Chancroid; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinati | 1983 |
Treatment of chancroid. Comparison of sulfamethoxazole-trimethoprim with recommended therapies.
Topics: Chancroid; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Male; Random Allocation; Str | 1981 |
Treatment of chancroid with single-dose doxycycline compared with a two-day course of co-trimoxazole.
Topics: Adolescent; Adult; Chancroid; Clinical Trials as Topic; Doxycycline; Drug Combinations; Female; Huma | 1981 |
Sulphaphenazole, streptomycin and sulphaphenazole combination, trimethoprim, and erythromycin in the treatment of chancroid.
Topics: Administration, Oral; Adult; Chancroid; Drug Therapy, Combination; Erythromycin; Female; Humans; Inj | 1990 |
Treating chancroid with enoxacin.
Topics: Adolescent; Adult; Anti-Infective Agents; Chancroid; Clinical Trials as Topic; Drug Therapy, Combina | 1988 |
The treatment of chancroid.
Topics: Amoxicillin; Anti-Bacterial Agents; Ceftriaxone; Chancroid; Clavulanic Acid; Clavulanic Acids; Clini | 1986 |
Treatment of chancroid with ciprofloxacin. A prospective, randomized clinical trial.
Topics: Adolescent; Adult; Chancroid; Ciprofloxacin; Clinical Trials as Topic; Double-Blind Method; Drug Com | 1987 |
Trimethoprim sulphamoxole in the treatment of chancroid. Comparison of two single dose treatment regimens with a five day regimen.
Topics: Adult; Chancroid; Drug Administration Schedule; Drug Combinations; Haemophilus ducreyi; Humans; Male | 1985 |
Short-course treatment of chancroid with co-trimoxazole (Septrin)
Topics: Adult; Chancroid; Clinical Trials as Topic; Drug Combinations; Humans; Male; Sulfamethoxazole; Trime | 1985 |
26 other studies available for trimethoprim and Chancroid
| Article | Year |
|---|---|
Herpes simplex infection simulating a positive auto-inoculation for Haemophilus ducreyi.
Topics: Adult; Autoantibodies; Chancroid; Diagnosis, Differential; Drug Combinations; Female; Haemophilus du | 1982 |
A case of mixed chancre.
Topics: Adult; Chancre; Chancroid; Drug Combinations; Haemophilus ducreyi; Humans; Male; Penicillin G Benzat | 1984 |
Therapy of chancroid with trimethoprim-sulfametrole.
Topics: Chancroid; Drug Combinations; Humans; Male; Sulfanilamides; Trimethoprim | 1983 |
Update on chancroid.
Topics: Administration, Oral; Chancroid; Drug Therapy, Combination; Erythromycin; Female; Humans; Male; Sulf | 1983 |
[An epidemic of chancroid. 587 cases (author's transl)].
Topics: Adult; Chancroid; Disease Outbreaks; Drug Combinations; Female; Humans; Lymphadenitis; Male; Paris; | 1982 |
[Reappearance of soft chancre: comments on the current epidemic in Paris (author's transl)].
Topics: Adolescent; Adult; Aged; Chancroid; Disease Outbreaks; Drug Combinations; Female; Humans; Male; Midd | 1980 |
Sexually transmitted diseases and human immunodeficiency virus control in Malawi: a field study of genital ulcer disease.
Topics: Chancroid; Ciprofloxacin; Erythromycin; Genital Diseases, Male; HIV Infections; Humans; Malawi; Male | 1995 |
In vitro susceptibility of Haemophilus ducreyi to several antibiotics.
Topics: Anti-Bacterial Agents; Ceftriaxone; Chancroid; Ciprofloxacin; Erythromycin; Haemophilus ducreyi; Hum | 1993 |
[Soft ulcer: problems in diagnosis and therapy].
Topics: Adult; Chancroid; Disease Reservoirs; Drug Therapy, Combination; Gentamicins; Humans; Male; Middle A | 1979 |
[Diagnosis and therapy of chancroid].
Topics: Adult; Chancroid; Drug Combinations; Haemophilus ducreyi; Humans; Lymphadenitis; Male; Sulfamethoxaz | 1979 |
Treatment of chancroid with Bactrim.
Topics: Administration, Oral; Chancroid; Drug Combinations; Humans; Injections, Intramuscular; Male; Sulfame | 1979 |
Rising incidence of chancroid in Rotterdam. Epidemiological, clinical, diagnostic, and therapeutic aspects.
Topics: Adult; Chancroid; Drug Combinations; Female; Humans; Male; Middle Aged; Netherlands; Retrospective S | 1979 |
[Soft chancre in Dakar (apropos of 1,585 cases)].
Topics: Adult; Chancroid; Female; Humans; Male; Middle Aged; Senegal; Streptomycin; Sulfadoxine; Sulfamethox | 1978 |
Reappraisal of the problem of British mariners and sexually transmitted infection.
Topics: Chancroid; Epidemiologic Methods; Female; Gonorrhea; Health Facilities; Humans; Male; Naval Medicine | 1976 |
Treating chancroid: summary of studies in southern Africa.
Topics: 4-Quinolones; Africa, Southern; Anti-Infective Agents; Chancroid; Erythromycin; Humans; Sulfonamides | 1989 |
An outbreak of chancroid in Orange County, California: descriptive epidemiology and disease-control measures.
Topics: California; Chancroid; Disease Outbreaks; Female; Haemophilus ducreyi; Humans; Male; Microbial Sensi | 1985 |
Chancroid in El Salvador. Increasing incidence, clinical features, and therapeutics.
Topics: Adolescent; Adult; Chancroid; Drug Combinations; El Salvador; Female; Groin; Humans; Lymphadenitis; | 1988 |
Leads from the MMWR. Chancroid--Massachusetts.
Topics: Boston; Chancroid; Disease Outbreaks; Drug Combinations; Erythromycin; Female; Genital Diseases, Fem | 1986 |
[Case report of an atypical course of chancroid].
Topics: Adult; Anti-Bacterial Agents; Chancroid; Drug Combinations; Drug Resistance; Humans; Male; Sulfamera | 1986 |
The diagnosis and treatment of chancroid.
Topics: Adult; Chancroid; Disease Outbreaks; Female; Hispanic or Latino; Humans; Male; Mexico; Middle Aged; | 1986 |
Comparative study of ceftriaxone and trimethoprim-sulfamethoxazole for the treatment of chancroid in Thailand.
Topics: Administration, Oral; Adult; Ceftriaxone; Chancroid; Drug Combinations; Drug Resistance, Microbial; | 1985 |
[Ulcus molle: clinical, diagnostic and therapeutic aspects].
Topics: Adult; Chancroid; Diagnosis, Differential; Drug Combinations; Haemophilus ducreyi; Humans; Male; Mid | 1985 |
Chancroid--Massachusetts.
Topics: Boston; Chancroid; Disease Outbreaks; Drug Combinations; Erythromycin; Female; Genital Diseases, Fem | 1985 |
[The soft chancre. Apropos of 55 new cases].
Topics: Anti-Bacterial Agents; Chancroid; Diagnosis, Differential; Drug Therapy, Combination; Folic Acid Ant | 1974 |
Treatment of venereal diseases.
Topics: Chancroid; Drug Combinations; Erythromycin; Female; Gonorrhea; Granuloma Inguinale; Humans; Injectio | 1973 |
Experience with doxycycline (Vibramycin) in the treatment of chancroid.
Topics: Chancroid; Cicatrix; Doxycycline; Drug Resistance, Microbial; Edema; Female; Gonorrhea; Humans; Male | 1974 |