Pityriasis Rosea

A mild exanthematous inflammation of unknown etiology. It is characterized by the presence of salmon-colored maculopapular lesions. The most striking feature is the arrangement of the lesions such that the long axis is parallel to the lines of cleavage. The eruptions are usually generalized, affecting chiefly the trunk, and the course is often self-limiting.

Synonym
Pityriasis Rosea

Excerpt	Reference
"Pityriasis rosea is a relatively common skin disorder."	( Ahmed, I; Charles-Holmes, R, 2000)
"Pityriasis rosea is a skin disease characterized by sharply defined pruritic red patches covered by fine scales."	( Bukhari, I, 2005)
"Pityriasis rosea is a common, acute eruption of uncertain etiology."	( Aste, N; Atzori, L; Ferreli, C; Pinna, AL, 2006)
"Pityriasis rosea is a scaly rash that mainly affects young adults."	( Chu, F; Chuh, AA; Comisel, GG; Dofitas, BL; Garner, SE; Reveiz, L; Sharma, V, 2007)
"Pityriasis rosea is a dermatological disease with a well-documented clinical appearance, but less is known about causes and treatment."	( Guo, M; Mattox, A; Voss, V, 2017)
"Pityriasis rosea is a common, self-limited and inflammatory skin disease."	( Çölgeçen, E; Gürel, G; Şahin, S, 2018)
"Pityriasis rosea is a papulosquamous skin disorder that occurs most commonly between the ages of 10 and 35 years."	( Li, A; Li, P; Li, W; Li, Y, 2018)

Excerpt	Reference
"Acyclovir may be effective in the treatment of pityriasis rosea, especially in patients treated in the first week from onset, when replicative viral activity of HHV is probably very high."	( Drago, F; Rebora, A; Vecchio, F, 2006)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	8 (11.43)	23.3326
1990's	3 (4.29)	12.5806
2000's	30 (42.86)	18.1394
2010's	24 (34.29)	28.8240
2020's	5 (7.14)	9.53

Drug	Relationship Strength	Studies	Trials
bupropion	low	1	0
atenolol	low	1	0
benfluorex	low	1	0
cacodylic acid	low	1	0
cetirizine	low	2	0
cetyltrimethylammonium ion	low	1	0
ciclopirox	low	1	0
valproic acid	low	1	0
ebastine	low	1	0
fenfluramine	low	1	0
hydrochlorothiazide	low	2	0
hydroxyzine	low	1	0
lamotrigine	low	1	0
nortriptyline	low	1	0
omeprazole	low	1	0
ondansetron	low	1	0
trimeprazine	low	1	0
hydrocortisone acetate	low	1	0
prednisolone	medium	1	1
prednisone	low	2	0
lysine	low	1	0
fluocinolone acetonide	low	1	0
pantothenic acid	low	1	0
methylprednisolone	low	1	0
ergotamine	low	1	0
diatrizoate meglumine	low	1	0
betamethasone	low	1	0
erythromycin	medium	8	3
zinc oxide	low	1	0
glycyrrhizic acid	low	1	0
phenyl acetate	low	1	0
triamcinolone	low	1	0
ribavirin	low	1	0
permethrin	low	2	0
oseltamivir	low	1	0
clobetasone butyrate	low	1	0
clarithromycin	medium	2	1
imatinib mesylate	low	2	0
levofloxacin	low	1	0
asenapine	low	1	0
cortisone	low	1	0
mometasone furoate	low	1	0
tacrolimus	low	1	0
zithromax	medium	3	2
riboflavin	low	1	0
terbinafine	low	2	0
vitamin d 2	low	1	0
isotretinoin	low	1	0
clobetasol	low	1	0
aluminum	low	1	0
bismuth	low	3	0
lisinopril	low	1	0
phosphatidylcholines	low	1	0
bismuth subsalicylate	low	1	0
piperidines	low	1	0
interleukin-8	low	1	0
salicylates	low	1	0
1 alpha,24-dihydroxyvitamin d3	low	1	0
acyclovir	medium	9	2

Protein Targets (728)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	7	0	0	7
Chain B, HADH2 protein	7	0	0	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Ferritin light chain	4	0	0	4
Thymidine kinase	0	1	0	1
thioredoxin reductase	12	0	0	12
phosphopantetheinyl transferase	3	0	0	3
GLS protein	6	0	0	6
TDP1 protein	28	0	0	28
Smad3	3	0	0	3
thyroid stimulating hormone receptor	6	0	0	6
EWS/FLI fusion protein	11	0	0	11
arylsulfatase A	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	20	0	0	20
activating transcription factor 6	8	0	0	8
Histone H2A.x	7	0	0	7
Bloom syndrome protein isoform 1	6	0	0	6
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
lamin isoform A-delta10	19	0	0	19
Solute carrier family 22 member 1	0	1	0	2
ATP-binding cassette sub-family C member 3	0	26	0	26
Multidrug resistance-associated protein 4	0	26	0	26
Solute carrier family 22 member 6	0	1	0	2
Bile salt export pump	0	4	0	4
Bile salt export pump	0	33	0	33
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	9	0	10
Cytochrome P450 2J2	0	7	0	8
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	0	0	1
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Canalicular multispecific organic anion transporter 1	0	25	0	25
Thymidine kinase	0	1	0	1
Alpha-1D adrenergic receptor	0	10	0	10
Alpha-1A adrenergic receptor	0	4	0	4
Histamine H1 receptor	0	13	4	19
Alpha-1B adrenergic receptor	0	4	0	4
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	7	0	0	7
AR protein	26	0	0	26
regulator of G-protein signaling 4	4	0	0	4
Beta-1 adrenergic receptor	0	1	1	2
D(1A) dopamine receptor	6	0	0	6
DNA polymerase iota isoform a (long)	8	0	0	8
geminin	28	0	0	28
Gamma-aminobutyric acid receptor subunit pi	9	3	1	13
Fatty acid-binding protein, liver	0	2	0	2
Urease	0	1	0	1
Beta-2 adrenergic receptor	0	4	1	5
Beta-1 adrenergic receptor	0	4	1	5
Beta-3 adrenergic receptor	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	9	3	1	13
Gamma-aminobutyric acid receptor subunit delta	9	3	1	13
Gamma-aminobutyric acid receptor subunit gamma-2	9	3	1	13
5-hydroxytryptamine receptor 1A	0	8	1	9
Gamma-aminobutyric acid receptor subunit alpha-5	9	3	1	13
Gamma-aminobutyric acid receptor subunit alpha-3	9	3	1	13
Gamma-aminobutyric acid receptor subunit gamma-1	9	3	1	13
Gamma-aminobutyric acid receptor subunit alpha-2	9	3	1	13
Gamma-aminobutyric acid receptor subunit alpha-4	9	3	1	13
Gamma-aminobutyric acid receptor subunit gamma-3	9	3	1	13
Gamma-aminobutyric acid receptor subunit alpha-6	9	3	1	13
Gamma-aminobutyric acid receptor subunit alpha-1	9	3	1	13
Gamma-aminobutyric acid receptor subunit beta-3	9	3	1	13
Gamma-aminobutyric acid receptor subunit beta-2	9	3	1	13
TAR DNA-binding protein 43	5	0	0	5
Beta-2 adrenergic receptor	0	0	1	1
GABA theta subunit	9	3	1	13
Gamma-aminobutyric acid receptor subunit epsilon	9	3	1	13
ATP-dependent phosphofructokinase	5	0	0	5
Chain A, Beta-lactamase	9	0	0	9
chromobox protein homolog 1	13	0	0	13
pregnane X receptor	5	0	0	5
GLI family zinc finger 3	22	0	0	22
progesterone receptor	19	0	0	19
cytochrome P450 family 3 subfamily A polypeptide 4	20	0	0	20
glucocorticoid receptor [Homo sapiens]	26	0	0	26
estrogen-related nuclear receptor alpha	26	0	0	26
farnesoid X nuclear receptor	14	0	0	14
pregnane X nuclear receptor	22	0	0	22
estrogen nuclear receptor alpha	31	0	0	31
vitamin D (1,25- dihydroxyvitamin D3) receptor	14	0	0	14
IDH1	8	0	0	8
aryl hydrocarbon receptor	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	17	0	0	17
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
thyroid hormone receptor beta isoform a	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 2	10	0	0	10
galanin receptor type 3	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	20	0	0	20
Voltage-dependent calcium channel gamma-2 subunit	11	0	0	11
Glucocorticoid receptor	0	17	2	24
Glycine receptor subunit alpha-1	0	16	0	16
Glutamate receptor 2	11	0	0	11
Glycine receptor subunit beta	0	16	0	16
Glycine receptor subunit alpha-2	0	16	0	16
Glycine receptor subunit alpha-3	0	16	0	16
ORF73	0	0	1	1
Luciferase	9	0	0	9
Spike glycoprotein	17	0	2	19
USP1 protein, partial	7	0	0	7
histone acetyltransferase KAT2A isoform 1	4	0	0	4
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Integrin alpha-5	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	3	0	5
Neuronal acetylcholine receptor subunit beta-2	0	3	0	4
UDP-glucuronosyltransferase 1-6	0	2	0	3
Cytochrome P450 2B6	0	0	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	2	0	4
Sodium-dependent noradrenaline transporter	0	12	0	12
Sodium-dependent dopamine transporter	0	4	0	4
Neuronal acetylcholine receptor subunit beta-4	0	2	0	3
Sodium-dependent serotonin transporter	0	10	0	10
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Cytochrome P450 2C19	0	5	0	7
UDP-glucuronosyltransferase 2B10	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	3	0	4
Sodium-dependent dopamine transporter	0	9	0	9
Acetylcholine receptor subunit delta	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
estrogen receptor 2 (ER beta)	11	0	0	11
retinoic acid nuclear receptor alpha variant 1	23	0	0	23
retinoid X nuclear receptor alpha	17	0	0	17
peroxisome proliferator-activated receptor delta	14	0	0	14
v-jun sarcoma virus 17 oncogene homolog (avian)	10	0	0	10
thyroid hormone receptor beta isoform 2	19	0	0	19
heat shock protein beta-1	10	0	0	10
DNA polymerase kappa isoform 1	2	0	0	2
survival motor neuron protein isoform d	9	0	0	9
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
Angiopoietin-1 receptor	0	0	1	1
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Multidrug and toxin extrusion protein 1	0	6	0	6
Histamine H4 receptor	0	5	1	6
interferon gamma precursor	0	0	0	1
Fumarate hydratase	6	0	0	6
PPM1D protein	3	0	0	3
polyprotein	6	0	0	6
Isocitrate dehydrogenase [NADP] cytoplasmic	0	1	0	1
Lysine-specific demethylase 4B	0	1	0	1
Interferon beta	16	0	0	16
Hypoxia-inducible factor 1-alpha	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
importin subunit beta-1 isoform 1	2	0	0	2
mitogen-activated protein kinase 1	7	0	0	7
snurportin-1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
streptokinase A precursor	0	0	4	4
ATP-dependent translocase ABCB1	0	9	0	12
Cytochrome P450 3A4	0	8	0	10
Solute carrier organic anion transporter family member 1B3	0	4	0	4
Solute carrier organic anion transporter family member 1B1	0	5	0	5
peroxisome proliferator activated receptor gamma	10	0	0	10
glp-1 receptor, partial	6	0	0	6
RAR-related orphan receptor gamma	17	0	0	17
Microtubule-associated protein tau	6	0	0	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
nuclear receptor subfamily 1, group I, member 3	15	0	0	15
nonstructural protein 1	3	0	0	3
G	12	0	0	12
cytochrome P450 2D6	14	0	0	14
thyroid stimulating hormone receptor	11	0	0	11
nuclear receptor ROR-gamma isoform 1	10	0	0	10
neuropeptide S receptor isoform A	2	0	0	2
HLA class I histocompatibility antigen, B alpha chain	12	0	0	12
Cellular tumor antigen p53	18	0	0	18
Guanine nucleotide-binding protein G	4	0	0	4
Inositol hexakisphosphate kinase 1	12	0	0	12
cytochrome P450 2C9, partial	12	0	0	12
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
5-hydroxytryptamine receptor 3E	0	2	1	4
acetylcholinesterase	10	0	0	10
ATAD5 protein, partial	9	0	0	9
NFKB1 protein, partial	2	0	0	2
caspase 7, apoptosis-related cysteine protease	4	0	0	4
glucocerebrosidase	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
caspase-3	4	0	0	4
Adenylate cyclase type 1	0	1	0	1
cytochrome P450 2D6 isoform 1	4	0	0	4
peripheral myelin protein 22 isoform 1	8	0	0	8
cytochrome P450 2C19 precursor	4	0	0	4
cytochrome P450 2C9 precursor	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	12	0	0	12
DNA polymerase beta	2	0	0	2
short transient receptor potential channel 6 isoform 1	0	0	1	1
peripheral myelin protein 22	7	0	0	7
cytochrome P450 3A4 isoform 1	9	0	0	9
M-phase phosphoprotein 8	3	0	0	3
transient receptor potential cation channel subfamily V member 1	1	0	0	1
muscarinic acetylcholine receptor M1	6	0	0	6
lethal factor (plasmid)	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
5-hydroxytryptamine receptor 3A	0	1	1	2
5-hydroxytryptamine receptor 4	0	10	0	10
5-hydroxytryptamine receptor 3B	0	2	1	4
Albumin	0	0	1	1
Aldo-keto reductase family 1 member B1	0	11	0	11
Muscarinic acetylcholine receptor M2	0	8	1	9
Muscarinic acetylcholine receptor M4	0	8	1	9
Muscarinic acetylcholine receptor M1	0	3	0	3
Muscarinic acetylcholine receptor M3	0	3	0	3
Muscarinic acetylcholine receptor M4	0	2	0	2
5-hydroxytryptamine receptor 1A	0	4	0	4
5-hydroxytryptamine receptor 2C	0	4	0	4
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M5	0	8	0	8
Alpha-2A adrenergic receptor	0	10	0	10
Calmodulin-1	0	1	0	1
Beta-2 adrenergic receptor	0	3	0	3
Cytochrome P450 2D6	0	2	0	3
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M1	0	8	1	9
Angiotensin-converting enzyme	0	8	0	8
D(2) dopamine receptor	0	8	0	11
5-hydroxytryptamine receptor 2A	0	4	0	4
Alpha-1B adrenergic receptor	0	8	1	9
Alpha-2B adrenergic receptor	0	12	0	12
Beta-1 adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	8	0	8
D	0	3	0	3
D(3) dopamine receptor	0	3	0	3
Alpha-2B adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	8	1	9
Endothelin receptor type B	0	1	0	1
D(1A) dopamine receptor	0	8	0	9
D(4) dopamine receptor	0	4	0	6
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	1	0	1
Alpha-2C adrenergic receptor	0	2	1	3
Alpha-2A adrenergic receptor	0	3	1	4
Alpha-1D adrenergic receptor	0	5	1	6
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	8	0	8
Adenosine receptor A1	0	1	0	1
D(1B) dopamine receptor	0	3	0	3
Beta-3 adrenergic receptor	0	2	0	2
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
5-hydroxytryptamine receptor 2A	0	12	0	14
5-hydroxytryptamine receptor 2C	0	10	1	11
5-hydroxytryptamine receptor 1B	0	7	0	7
5-hydroxytryptamine receptor 1D	0	4	0	4
D(4) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 1F	0	4	0	4
5-hydroxytryptamine receptor 2B	0	4	1	5
Histamine H1 receptor	0	2	1	3
Histamine H1 receptor	0	4	0	4
Sodium-dependent serotonin transporter	0	1	1	2
5-hydroxytryptamine receptor 7	0	3	0	3
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
5-hydroxytryptamine receptor 2A	0	1	0	1
D(3) dopamine receptor	0	10	0	12
5-hydroxytryptamine receptor 3A	0	4	1	5
Adenylate cyclase type 8	0	1	0	1
5-hydroxytryptamine receptor 2B	0	16	1	17
Alpha-1A adrenergic receptor	0	9	1	10
5-hydroxytryptamine receptor 3A	0	3	1	5
Histamine H2 receptor	7	1	0	10
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 6	0	10	0	12
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	3	0	3
Calmodulin	0	0	1	1
Inositol monophosphatase 1	5	0	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
5-hydroxytryptamine receptor 2B	0	1	0	1
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	6	0	6
5-hydroxytryptamine receptor 3D	0	2	1	4
Adenylyl cyclase 7	0	1	0	1
5-hydroxytryptamine receptor 3C	0	2	1	4
D	0	2	0	2
ATPase family AAA domain-containing protein 5	10	0	0	10
Ataxin-2	12	0	0	12
Sigma non-opioid intracellular receptor 1	0	3	0	3
5-hydroxytryptamine receptor 3B	0	4	1	5
Sigma non-opioid intracellular receptor 1	0	3	0	3
Transporter	0	1	0	1
Histamine H3 receptor	0	1	0	1
endonuclease IV	1	0	0	1
dopamine D1 receptor	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	10	0	0	10
flap endonuclease 1	3	0	0	3
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	3	0	3
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
thioredoxin glutathione reductase	4	0	0	4
vitamin D3 receptor isoform VDRA	6	0	0	6
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
Sodium-dependent neutral amino acid transporter B(0)AT2	0	2	0	2
Hsf1 protein	0	0	2	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	3	0	3
Glycine receptor subunit alpha-1	0	0	1	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	0	2	0	2
SMAD family member 2	9	0	0	9
SMAD family member 3	9	0	0	9
Caspase-7	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
caspase-3	3	0	0	3
huntingtin isoform 2	3	0	0	3
ras-related protein Rab-9A	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
Epidermal growth factor receptor	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Amyloid-beta precursor protein	1	0	0	1
Tyrosine-protein kinase Fyn	0	2	0	2
Adenosine receptor A3	0	5	0	5
Replicase polyprotein 1ab	0	1	2	3
Substance-K receptor	0	2	0	2
Acetylcholinesterase	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Alpha-synuclein	1	0	0	1
D(1A) dopamine receptor	2	0	0	2
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	3	0	3
Thromboxane-A synthase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Motilin receptor	0	0	1	1
acid sphingomyelinase	1	0	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
serine/threonine-protein kinase PLK1	3	0	0	3
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
30S ribosomal protein S6	0	2	1	3
30S ribosomal protein S7	0	2	1	3
50S ribosomal protein L15	0	2	1	3
Albumin	0	1	1	2
60 kDa chaperonin	0	3	0	3
50S ribosomal protein L10	0	2	1	3
50S ribosomal protein L11	0	2	1	3
50S ribosomal protein L7/L12	0	2	1	3
50S ribosomal protein L19	0	2	1	3
50S ribosomal protein L1	0	2	1	3
50S ribosomal protein L20	0	2	1	3
50S ribosomal protein L27	0	2	1	3
50S ribosomal protein L28	0	2	1	3
50S ribosomal protein L29	0	2	1	3
50S ribosomal protein L31	0	2	1	3
50S ribosomal protein L31 type B	0	2	1	3
50S ribosomal protein L32	0	2	1	3
50S ribosomal protein L33	0	2	1	3
50S ribosomal protein L34	0	2	1	3
50S ribosomal protein L35	0	2	1	3
50S ribosomal protein L36	0	2	1	3
30S ribosomal protein S10	0	2	1	3
30S ribosomal protein S11	0	2	1	3
30S ribosomal protein S12	0	2	1	3
30S ribosomal protein S13	0	2	1	3
30S ribosomal protein S16	0	2	1	3
30S ribosomal protein S18	0	2	1	3
30S ribosomal protein S19	0	2	1	3
30S ribosomal protein S20	0	2	1	3
30S ribosomal protein S2	0	2	1	3
30S ribosomal protein S3	0	2	1	3
30S ribosomal protein S4	0	2	1	3
30S ribosomal protein S5	0	2	1	3
30S ribosomal protein S8	0	2	1	3
30S ribosomal protein S9	0	2	1	3
50S ribosomal protein L13	0	2	1	3
50S ribosomal protein L14	0	2	1	3
50S ribosomal protein L16	0	2	1	3
50S ribosomal protein L23	0	2	1	3
30S ribosomal protein S15	0	2	1	3
50S ribosomal protein L17	0	2	1	3
50S ribosomal protein L21	0	2	1	3
50S ribosomal protein L30	0	2	1	3
50S ribosomal protein L6	0	2	1	3
30S ribosomal protein S14	0	2	1	3
30S ribosomal protein S17	0	2	1	3
30S ribosomal protein S1	0	2	1	3
50S ribosomal protein L18	0	2	1	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	2	1	3
50S ribosomal protein L3	0	2	1	3
50S ribosomal protein L24	0	2	1	3
50S ribosomal protein L4	0	2	1	3
50S ribosomal protein L22	0	2	1	3
10 kDa heat shock protein, mitochondrial	0	3	0	3
50S ribosomal protein L5	0	2	1	3
30S ribosomal protein S21	0	2	1	3
50S ribosomal protein L25	0	2	1	3
Cytochrome P450 1B1	0	1	0	1
Thiosulfate sulfurtransferase	0	3	0	3
Lanosterol 14-alpha demethylase	0	1	0	1
50S ribosomal protein L36 2	0	2	1	3
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	0	1	0	1
Androgen receptor	0	4	0	4
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
Chain A, 2-oxoglutarate Oxygenase	3	0	0	3
Glycogen phosphorylase, muscle form	0	1	0	1
Pancreatic alpha-amylase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
High mobility group protein B1	0	0	1	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	1	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	1	2
High mobility group protein B1	0	0	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 2	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	1	0	1
Solute carrier organic anion transporter family member 1B2	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	5	0	0	5
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 12	0	1	0	1
Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 6	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Carbonic anhydrase 9	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	1	2	3
Transmembrane protease serine 2	0	0	2	2
Procathepsin L	0	0	2	2
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Angiotensin-converting enzyme 2	0	0	2	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Tyrosine-protein kinase ABL1	0	1	1	2
Cytochrome P450 2C8	0	1	0	2
Mast/stem cell growth factor receptor Kit	0	1	1	2
Breakpoint cluster region protein	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	1	2
Cytochrome P450 3A5	0	1	0	2
Chain A, Cruzipain	2	0	0	2
67.9K protein	3	0	0	3
Parkin	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
DNA polymerase eta isoform 1	1	0	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	1	0	1
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Mitogen-activated protein kinase 14	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Olfactory receptor 51E2	0	1	0	1
GALC protein	1	0	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
15-lipoxygenase, partial	2	0	0	2
Thrombopoietin	3	0	0	3
isocitrate dehydrogenase 1, partial	2	0	0	2
alpha-galactosidase	2	0	0	2
cellular tumor antigen p53 isoform a	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Integrin beta-3	2	1	0	3
Integrin alpha-IIb	2	1	0	3
Platelet-activating factor receptor	0	1	0	1
Bile acid receptor	0	1	0	1
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Cationic amino acid transporter 3	0	1	0	1
muscleblind-like protein 1 isoform 1	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Progesterone receptor	0	2	1	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
5-hydroxytryptamine receptor 6	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 5B	0	2	0	2
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Cytochrome P450 2D4	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
ClpP	1	0	0	1
Mcl-1	0	1	0	1
apical membrane antigen 1, AMA1	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
pyruvate kinase PKM isoform a	1	0	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
Fatty acid synthase	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Interleukin-6 receptor subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Thyrotropin-releasing hormone receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Glycine receptor subunit alpha-4	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Histamine H3 receptor	0	1	0	1
Leukotriene B4 receptor 1	0	1	0	1
Nischarin	0	1	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Sialidase	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Liver carboxylesterase 1	0	1	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Nuclear receptor ROR-gamma	4	0	0	4
NS5	0	0	1	1
interleukin 8	2	0	0	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
NPYLR7B	0	0	1	1
thyrotropin-releasing hormone receptor	1	0	0	1
tumor necrosis factor	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Riboflavin-binding protein	0	1	1	2
Caspase-7	1	0	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
C-8 sterol isomerase	0	1	0	1
Squalene monooxygenase	0	1	0	1
Squalene monooxygenase	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Trypanothione reductase	0	2	0	2
Cocaine esterase	0	1	0	1
Histone deacetylase 3	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	0	0	1
Cytochrome P450 2A6	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Histone deacetylase 1	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
eyes absent homolog 2 isoform a	1	0	0	1
Vitamin D3 receptor	0	0	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
Protein-arginine deiminase type-4	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (70)

Protein Targets (728)

Pityriasis Rosea

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (70)

Drugs Studied (64)

Protein Targets (728)