Page last updated: 2024-09-28

Brown Lung

A condition of BRONCHOCONSTRICTION resulting from hypersensitive reaction to inhaled dust during the initial processing of cotton, flax, or hemp in the textile industry. Symptoms include wheezing and tightness in the chest.

Synonyms(3)

Synonym
Byssinosis
Brown Lung
Brown Lung Disease

Research Excerpts

Overview

ExcerptReference
"Byssinosis is a hazardous respiratory disorder of workers in natural fiber processing industries and, in the case of cotton, is caused by exposure to respirable dust generated from leafy trash associated with raw fibers."( Buck, MG; Hinojosa, O; Jacks, TJ; Lillehoj, EB; Wall, JH, 1989)
"Byssinosis is an occupational disease of textile workers caused by exposure to the bract portion of the cotton plant in the form of mill dust."( Hanson, MN; Johnson, CM; Rohrbach, MS, 1986)
"Byssinosis is an occupational respiratory disease contracted by cotton mill workers who inhale cotton mill dust."( Ainsworth, SK; Bray, VJ; Cordova-Salinas, M; Mundie, TG, 1983)
"Byssinosis is a rare respiratory symptom in cotton weaving."( Faragher, EB; Fletcher, AM; Niven, RM; Pickering, CA; Raza, SN, 1999)
"Byssinosis is more strongly associated with exposure to endotoxin than to dust."( Christiani, DC; Dai, HL; Eisen, EA; Olenchock, SA; Pan, LD; Sun, BX; Wang, XR; Wegman, DH; Zhang, HX, 2003)
"Byssinosis is an occupational lung disease observed among workers exposed to cotton, flax, and hemp dust."( Chadha, S; Das, A; Kundu, D; Sagili, K, 2019)
"Byssinosis is highly prevalent in "home-based" power loom units in Madhya Pradesh."( Chadha, S; Das, A; Kundu, D; Sagili, K, 2019)

Context

ExcerptReference
"Research to control byssinosis has focused on methods to reduce the trash associated with harvested fiber and control the dust in the textile mill environment."( Jacobs, RR, 1987)
"The problem of byssinosis has plagued cotton textile mills for hundreds of years, and it is still a problem today."( Niles, GA; Parnell, CB; Rutherford, RD, 1986)

Research

Studies (299)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990236 (78.93)23.3326
1990's35 (11.71)12.5806
2000's13 (4.35)18.1394
2010's7 (2.34)28.8240
2020's8 (2.68)9.53
DrugIndicatedRelationship StrengthStudiesTrials
benzene0low20
citric acid, anhydrous0low10
chlorine0low10
malic acid0low10
histamine0low160
methanol0low20
oxamic acid0low10
sulfur dioxide0low10
5,5-dimethyl-1-pyrroline-1-oxide0low10
aa 8610low10
albuterol0medium22
pimagedine0low10
chlorpheniramine0low10
diphenhydramine0low10
berotek0low10
gossypol0low10
guaifenesin0low10
indomethacin0low20
isoproterenol0medium21
metaproterenol0low90
apnea0low10
promethazine0medium11
propranolol0low30
galactose0low10
methacholine chloride0low20
cycloheximide0low10
mannitol0low30
tryptophan0low10
isocyanic acid0low10
ethylene oxide0low10
phencyclidine0medium2293
tromethamine0low10
n-vinyl-2-pyrrolidinone0low30
bromphenol blue0low10
2-naphthol0low30
ephedrine0medium11
aminophylline0medium11
methysergide0low10
fusarium0low10
luminol0low10
toluene 2,4-diisocyanate0low30
zinc oxide0low40
paraquat0low10
beta-hydroxymyristic acid0low10
mannose0low10
helium0low10
poloxalene0low10
levamisole0low10
cromolyn sodium0medium31
colforsin0low10
fomesafen0low10
masoprocol0low10
nsc-1727550low10
arabitol0low10
plicatic acid0low10
cyanates0low10
1-hexadecyl-2-acetyl-glycero-3-phosphocholine0low10
deoxyglucose0low10
thromboxanes0low10
hydroxyl radical0low10
atropine0low10
lignin0low10
aflatoxin b10low10
elastin0low10
epiglucan0low10
laminaran0low10
n-formylmethionine0low10
leucocyanidin0low30
lignans0low10
n-formylmethionine leucyl-phenylalanine0low10
arachidonic acid0low30
sesquiterpenes0low10
D-fructopyranose0low10
dinoprost0low20
scopoletin0low10
leukotriene b40low10
thromboxane a20low10
humulene0low80
thromboxane b20low20
lysophosphatidylcholines0low10
cytochalasin b0low10
aluminum0low10
beryllium0low10
nitrofurantoin0low10
lodoxamide tromethamine0low10
tannins0low120
cellulose0low30
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one0medium11
interleukin-80low10
ascorbic acid0low30
caseins0low10
cyclic gmp0low10
concanavalin a0low10

Protein Targets (756)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
IDH16006
chromobox protein homolog 1140014
geminin140014
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE140014
Chain A, Cruzipain5005
regulator of G-protein signaling 4120012
Platelet-activating factor receptor0202
Inositol monophosphatase 15005
Luciferase9009
RAR-related orphan receptor gamma140014
GLI family zinc finger 3190019
AR protein200020
estrogen receptor 2 (ER beta)130013
nuclear receptor subfamily 1, group I, member 3130013
progesterone receptor110011
retinoic acid nuclear receptor alpha variant 1120012
retinoid X nuclear receptor alpha150015
pregnane X nuclear receptor130013
estrogen nuclear receptor alpha240024
peroxisome proliferator-activated receptor delta8008
aryl hydrocarbon receptor110011
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Histone H2A.x8008
thyroid hormone receptor beta isoform 2160016
nuclear factor erythroid 2-related factor 2 isoform 1170017
DNA repair and recombination protein RadA0011
Voltage-dependent calcium channel gamma-2 subunit7007
Cellular tumor antigen p53130013
Cytochrome P450 1A20202
Cytochrome P450 2A60101
Sulfotransferase 1A1 0001
Glutamate receptor 27007
Cytochrome P450 2A50101
Sulfotransferase 1E10001
Sulfotransferase 1A10001
Sulfotransferase 2A10001
thioredoxin reductase210021
thyroid stimulating hormone receptor9009
euchromatic histone-lysine N-methyltransferase 2240024
Bloom syndrome protein isoform 18008
muscarinic acetylcholine receptor M14004
ATP-dependent phosphofructokinase110011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Chain A, Putative fructose-1,6-bisphosphate aldolase6006
Chain A, JmjC domain-containing histone demethylation protein 3A3003
Chain A, 2-oxoglutarate Oxygenase100010
Chain A, Ferritin light chain3003
endonuclease IV2002
acetylcholinesterase6006
Nrf21001
15-lipoxygenase, partial4004
phosphopantetheinyl transferase9009
ATAD5 protein, partial6006
USP1 protein, partial120012
NFKB1 protein, partial3003
GLS protein120012
TDP1 protein180018
Microtubule-associated protein tau110011
thioredoxin glutathione reductase8008
Smad35005
aldehyde dehydrogenase 1 family, member A1120012
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)6006
cytochrome P450 family 3 subfamily A polypeptide 4100010
estrogen-related nuclear receptor alpha200020
G5005
cytochrome P450 2D69009
bromodomain adjacent to zinc finger domain 2B7007
peroxisome proliferator activated receptor gamma130013
arylsulfatase A100010
cytochrome P450 2D6 isoform 15005
hexokinase-4 isoform 15005
peripheral myelin protein 22 isoform 14004
cytochrome P450 2C19 precursor3003
cytochrome P450 2C9 precursor4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
vitamin D3 receptor isoform VDRA110011
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
potassium voltage-gated channel subfamily H member 2 isoform d7007
glucokinase regulatory protein5005
DNA polymerase beta4004
mitogen-activated protein kinase 14004
flap endonuclease 1100010
serine/threonine-protein kinase mTOR isoform 16006
serine/threonine-protein kinase PLK11001
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)9009
peripheral myelin protein 226006
survival motor neuron protein isoform d6006
cytochrome P450 3A4 isoform 18008
M-phase phosphoprotein 86006
histone acetyltransferase KAT2A isoform 17007
lamin isoform A-delta10170017
neuropeptide S receptor isoform A4004
Gamma-aminobutyric acid receptor subunit pi81110
Nuclear receptor subfamily 1 group I member 20022
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 5005
Polyunsaturated fatty acid 5-lipoxygenase0303
Polyunsaturated fatty acid 5-lipoxygenase0203
Gamma-aminobutyric acid receptor subunit beta-181110
Gamma-aminobutyric acid receptor subunit delta81110
Gamma-aminobutyric acid receptor subunit gamma-281110
Gamma-aminobutyric acid receptor subunit alpha-581110
Gamma-aminobutyric acid receptor subunit alpha-381110
Gamma-aminobutyric acid receptor subunit gamma-181110
Gamma-aminobutyric acid receptor subunit alpha-281110
Gamma-aminobutyric acid receptor subunit alpha-481110
Gamma-aminobutyric acid receptor subunit gamma-381110
Gamma-aminobutyric acid receptor subunit alpha-681110
Histamine H2 receptor5029
Polyunsaturated fatty acid 5-lipoxygenase0101
D(1A) dopamine receptor4004
Gamma-aminobutyric acid receptor subunit alpha-181110
Gamma-aminobutyric acid receptor subunit beta-381110
Gamma-aminobutyric acid receptor subunit beta-281110
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
GABA theta subunit81110
Inositol hexakisphosphate kinase 15005
Ataxin-2110011
Gamma-aminobutyric acid receptor subunit epsilon81110
cytochrome P450 2C9, partial5005
M17 leucyl aminopeptidase0101
Acetylcholinesterase0202
Acetylcholinesterase0202
glp-1 receptor, partial8008
NPYLR7B0022
thyroid stimulating hormone receptor6006
ATP-binding cassette sub-family C member 30808
Multidrug resistance-associated protein 40809
Bile salt export pump016016
Beta-2 adrenergic receptor07715
Beta-1 adrenergic receptor0448
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0202
Beta-3 adrenergic receptor0336
Delta-type opioid receptor0011
10 kDa heat shock protein, mitochondrial0202
Thiosulfate sulfurtransferase0202
Beta-2 adrenergic receptor 0136
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Beta-2 adrenergic receptor03610
Canalicular multispecific organic anion transporter 10808
D(1A) dopamine receptor6006
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN0011
Chain A, SERUM ALBUMIN0011
Chain A, SERUM ALBUMIN0011
Chain A, Beta-lactamase5005
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
cellular tumor antigen p53 isoform a5005
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
nuclear receptor ROR-gamma isoform 16006
lethal(3)malignant brain tumor-like protein 1 isoform I3003
DNA polymerase kappa isoform 19009
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
caspase-1 isoform alpha precursor3003
Fatty-acid amide hydrolase 10101
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Prostaglandin G/H synthase 1 0204
Trypsin0101
Coagulation factor VII0101
Aromatase0101
Tissue factor0101
Fatty acid-binding protein, adipocyte0112
Prostaglandin G/H synthase 20528
Nuclear receptor subfamily 4 group A member 20011
Calmodulin 0012
Disintegrin and metalloproteinase domain-containing protein 173003
Prostaglandin G/H synthase 20203
Solute carrier organic anion transporter family member 2A10104
Fatty acid-binding protein 50101
Fatty acid-binding protein 50011
Lanosterol 14-alpha demethylase0101
Solute carrier organic anion transporter family member 1B30606
Cytosolic phospholipase A2 gamma0202
Transient receptor potential cation channel subfamily V member 20101
Solute carrier organic anion transporter family member 1B10606
Chain A, Hyaluronidase, phage associated0101
glucocorticoid receptor [Homo sapiens]170017
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
nuclear factor erythroid 2-related factor 2 isoform 24004
lethal factor (plasmid)7007
Polyphenol oxidase 20101
Pancreatic alpha-amylase0202
Albumin0112
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0427
Spike glycoprotein4127
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
cystic fibrosis transmembrane conductance regulator0101
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0305
5-hydroxytryptamine receptor 4010010
Muscarinic acetylcholine receptor M207212
Muscarinic acetylcholine receptor M40619
Muscarinic acetylcholine receptor M10327
Muscarinic acetylcholine receptor M30327
Muscarinic acetylcholine receptor M40327
Muscarinic acetylcholine receptor M50327
Muscarinic acetylcholine receptor M50619
Muscarinic acetylcholine receptor M20328
Muscarinic acetylcholine receptor M107212
Muscarinic acetylcholine receptor M10013
Muscarinic acetylcholine receptor M307211
Alpha-1D adrenergic receptor0427
5-hydroxytryptamine receptor 2C010111
Muscarinic acetylcholine receptor M40113
5-hydroxytryptamine receptor 70505
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0112
Chain A, Integrase0101
Chain A, Integrase0101
Chain A, T4 LYSOZYME0011
Chain A, GCN4P10011
Chain B, GCN4P10011
Chain C, GCN4P10011
Chain A, T4 LYSOZYME0011
Chain A, T4 LYSOZYME0011
Chain A, Replicase polyprotein 1ab0101
Chain A, 3C-like proteinase0101
pregnane X receptor4004
Endolysin0011
Integrin beta-33003
Integrin alpha-IIb3003
beta-2 adrenergic receptor3003
G-protein coupled receptor 840112
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
activating transcription factor 66006
histone deacetylase 9 isoform 31001
ATPase family AAA domain-containing protein 55005
Carbonic anhydrase 10305
Carbonic anhydrase 20306
Carbonic anhydrase 40204
Carbonic anhydrase0103
Carbonic anhydrase 150204
atrial natriuretic peptide receptor 1 precursor3003
atrial natriuretic peptide receptor 2 precursor2002
Histamine H1 receptor08210
MBT domain-containing protein 10101
Potassium voltage-gated channel subfamily H member 20505
Solute carrier family 22 member 10304
Lethal(3)malignant brain tumor-like protein 40101
Lethal(3)malignant brain tumor-like protein 30101
Chloroquine resistance transporter0202
Solute carrier family 22 member 20304
Lethal(3)malignant brain tumor-like protein 10101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
farnesoid X nuclear receptor8008
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
thyroid hormone receptor beta isoform a5005
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0202
nuclear receptor subfamily 1, group I, member 21001
nuclear receptor subfamily 0 group B member 10101
steroidogenic factor 10101
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
relaxin receptor 1 isoform 11001
relaxin receptor 2 isoform 11001
Rap guanine nucleotide exchange factor 32002
ATP-dependent translocase ABCB10404
5-hydroxytryptamine receptor 1A0202
Solute carrier family 2, facilitated glucose transporter member 10314
Adenylate cyclase type 20011
Adenylate cyclase type 80011
Adenylate cyclase type 10112
Relaxin receptor 10011
Nuclear receptor subfamily 1 group I member 20011
Alkaline phosphatase, germ cell type0101
G protein-coupled receptor GPR350011
G-protein coupled receptor 350011
G-protein coupled receptor 350011
Phosphodiesterase 0101
Multidrug resistance-associated protein 50001
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
interleukin 82002
Fumarate hydratase3003
PPM1D protein3003
EWS/FLI fusion protein8008
polyprotein3003
67.9K protein5005
P531001
RPL19A0011
Spike glycoprotein0123
Replicase polyprotein 1ab0123
NPC intracellular cholesterol transporter 1 precursor3003
nuclear factor NF-kappa-B p105 subunit isoform 12002
ras-related protein Rab-9A5005
heat shock protein HSP 90-alpha isoform 20001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
transactivating tegument protein VP16 [Human herpesvirus 1]0101
COUP transcription factor 2 isoform a0101
Transmembrane protease serine 20123
Glucose transporter0101
Hexose transporter 1 0101
Procathepsin L0224
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Alpha-synuclein3003
Nuclear receptor ROR-gamma4004
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
TAR DNA-binding protein 432002
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0101
Endothelial PAS domain-containing protein 10101
Angiotensin-converting enzyme 2 0123
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0001
PINK12002
Parkin4004
neutrophil cytosol factor 10101
Solute carrier family 2, facilitated glucose transporter member 30101
Solute carrier family 2, facilitated glucose transporter member 40101
Solute carrier family 22 member 20002
Prostaglandin G/H synthase 2 0203
Thromboxane A2 receptor 0112
Prostaglandin G/H synthase 10202
Prostaglandin E2 receptor EP1 subtype0112
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin F2-alpha receptor0202
Prostaglandin F2-alpha receptor0213
Prostaglandin E2 receptor EP3 subtype0112
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin F2-alpha receptor0011
Prostacyclin receptor0101
Prostaglandin D2 receptor0101
Solute carrier family 22 member 60102
Solute carrier family 22 member 70002
Solute carrier family 22 member 80102
Solute carrier organic anion transporter family member 2A10103
Solute carrier organic anion transporter family member 2A10101
Solute carrier organic anion transporter family member 2B10101
Solute carrier family 22 member 110001
Solute carrier family 22 member 70001
Thrombopoietin2002
huntingtin isoform 23003
Aldo-keto reductase family 1 member B10505
Cytochrome P450 2C9 0303
Angiotensin-converting enzyme0202
Sodium-dependent noradrenaline transporter 0404
5-hydroxytryptamine receptor 2A0819
Histamine H1 receptor0124
5-hydroxytryptamine receptor 2B0819
Histamine N-methyltransferase0001
Cytochrome P450 2J20202
Sodium channel protein type 5 subunit alpha0202
Nuclear receptor subfamily 3 group C member 3 0202
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Histamine H4 receptor0224
Histamine H3 receptor0102
hypoxia-inducible factor 1 alpha subunit3003
importin subunit beta-1 isoform 13003
snurportin-13003
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Mcl-10101
SMAD family member 24004
SMAD family member 34004
Estrogen receptor 10101
DNA polymerase III, partial3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
Caspase-71001
lysosomal alpha-glucosidase preproprotein2002
galactokinase1001
polyunsaturated fatty acid lipoxygenase ALOX122002
caspase-31001
heat shock protein beta-12002
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
tyrosine-protein kinase Yes1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
eukaryotic translation initiation factor 4E isoform 10101
muscleblind-like protein 1 isoform 12002
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase1001
Prolyl endopeptidase0101
L-lactate dehydrogenase A chain0303
Malate dehydrogenase, mitochondrial0202
Beta-lactamase0101
L-lactate dehydrogenase B chain0303
Apoptosis regulator Bcl-20213
Malate dehydrogenase, cytoplasmic0202
Aldo-keto reductase family 1 member B10303
L-lactate dehydrogenase B chain0202
DNA-3-methyladenine glycosylase0101
Caspase-11103
DNA repair protein RAD52 homolog0101
Kinesin-like protein KIF110101
Caspase-73003
BH3-interacting domain death agonist0101
Type 1 InsP3 receptor isoform S2 1001
E3 ubiquitin-protein ligase Mdm20101
Bcl-2-like protein 10314
Induced myeloid leukemia cell differentiation protein Mcl-10415
Peroxisome proliferator-activated receptor alpha1001
L-lactate dehydrogenase0202
Aspartyl/asparaginyl beta-hydroxylase0101
L-lactate dehydrogenase0202
L-lactate dehydrogenase B chain0202
L-lactate dehydrogenase0202
Bcl-2-like protein 20101
Bcl2-associated agonist of cell death 0101
Inosine-5'-monophosphate dehydrogenase 0101
Histamine H3 receptor1001
phosphoglycerate kinase1001
2,3-bisphosphoglycerate-independent phosphoglycerate mutase2002
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
GALC protein2002
apical membrane antigen 1, AMA11001
transforming acidic coiled-coil-containing protein 30001
Carbonic anhydrase 120103
Solute carrier family 22 member 30102
Plasma kallikrein0002
Carbonic anhydrase 30002
Macrophage migration inhibitory factor0202
Carbonic anhydrase 60002
Histamine H2 receptor0325
Adenosine receptor A10102
5-hydroxytryptamine receptor 1D0001
Adenosine receptor A2a0102
Histamine H1 receptor0213
Metabotropic glutamate receptor 50112
Carbonic anhydrase 5A, mitochondrial0002
Glutamate receptor ionotropic, NMDA 1 0215
Carbonic anhydrase 70103
Carbonic anhydrase0003
Histamine H3 receptor0101
Glutamate receptor ionotropic, NMDA 2A 0215
Glutamate receptor ionotropic, NMDA 2B0215
Glutamate receptor ionotropic, NMDA 2C0216
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 90103
Carbonic anhydrase 0003
Carbonic anhydrase-like protein, putative0002
Carbonic anhydrase0003
Carbonic anhydrase0003
Glutamate receptor ionotropic, NMDA 2D0215
Carbonic anhydrase 0003
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130102
Glutamate receptor ionotropic, NMDA 3B0215
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 40001
Carbonic anhydrase 130002
Carboxylic ester hydrolase 0001
Glutamate receptor ionotropic, NMDA 3A0215
Carbonic anhydrase 140002
Carbonic anhydrase 5B, mitochondrial0002
Histamine H3 receptor0123
Chain A, membrane-associated prostaglandin E synthase-20101
glucocerebrosidase4004
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Solute carrier family 22 member 60101
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Epidermal growth factor receptor0101
Phospholipase A2, major isoenzyme0101
Albumin0134
Prostaglandin G/H synthase 10304
Neuronal acetylcholine receptor subunit alpha-40101
Interleukin-80101
Androgen receptor0011
Neuronal acetylcholine receptor subunit beta-20101
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Sodium-dependent dopamine transporter0101
Sodium- and chloride-dependent GABA transporter 10101
Thromboxane-A synthase 0101
Serum paraoxonase/arylesterase 10101
Indoleamine 2,3-dioxygenase 10101
Nitric oxide synthase, inducible0202
Substance-P receptor0202
Prostaglandin E2 receptor EP3 subtype0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 2 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G2002
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30101
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0202
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0101
Multidrug and toxin extrusion protein 10101
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Prostaglandin D2 receptor 20112
Beta-1 adrenergic receptor 0125
Bile salt export pump0303
Beta-2 adrenergic receptor0416
Polyunsaturated fatty acid lipoxygenase ALOX150202
D(2) dopamine receptor0617
Alpha-1B adrenergic receptor0314
Beta-1 adrenergic receptor0428
Beta-2 adrenergic receptor0011
Alpha-2B adrenergic receptor0213
D(1A) dopamine receptor0617
D(4) dopamine receptor0101
Alpha-2C adrenergic receptor0213
Alpha-2A adrenergic receptor0213
Alpha-1D adrenergic receptor0314
Beta-adrenergic receptor kinase 10022
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0314
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0213
Alpha-1A adrenergic receptor0135
Alpha-1B adrenergic receptor0023
D(3) dopamine receptor0505
Alpha-1A adrenergic receptor0314
Beta-2 adrenergic receptor0202
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0011
Taste receptor type 2 member 420011
Taste receptor type 2 member 160011
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
Leukotriene B4 receptor 10202
Leukotriene B4 receptor 20101
dopamine D1 receptor2002
Alkaline phosphatase, tissue-nonspecific isozyme0303
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0202
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Phospholipase A-2-activating protein0202
tumor necrosis factor1001
NEDD8-activating enzyme E1 regulatory subunit isoform a0101
NEDD8-conjugating enzyme Ubc120101
GTP-binding nuclear protein Ran isoform 12002
Queuine tRNA-ribosyltransferase0101
Methyl-accepting chemotaxis protein NahY0011
transcriptional regulator ERG isoform 31001
Alpha-mannosidase 2C10101
Fucose-binding lectin PA-IIL0101
CD209 antigen0101
ClpP1001
hypothetical protein, conserved1001
nonstructural protein 11001
alpha-galactosidase3003
Seed linoleate 13S-lipoxygenase-10101
Single-stranded DNA cytosine deaminase1001
thyrotropin-releasing hormone receptor1001
galanin receptor type 30101
Alpha-2A adrenergic receptor0528
5-hydroxytryptamine receptor 1A0618
5-hydroxytryptamine receptor 1B0606
5-hydroxytryptamine receptor 60617
Formyl peptide receptor-related sequence 10011
fMet-Leu-Phe receptor0224
N-formyl peptide receptor 20022
FML2_HUMAN 0011
streptokinase A precursor0011
Estrogen receptor0011
Estrogen receptor beta0011
CDGSH iron-sulfur domain-containing protein 10202
L-lactate dehydrogenase C chain0101
L-lactate dehydrogenase A chain0101
L-lactate dehydrogenase A chain0101
L-lactate dehydrogenase 0101
Photosystem I iron-sulfur center 0001
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Cytochrome P450 2B60101
Sodium-dependent serotonin transporter0101
Delta-type opioid receptor0001
Kappa-type opioid receptor0001
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 3A0101
Muscarinic acetylcholine receptor M50012
Sigma non-opioid intracellular receptor 10505
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sigma non-opioid intracellular receptor 10202
Neutrophil elastase0101
Complement C1s subcomponent0101
Nitric oxide synthase, endothelial0101
Nitric oxide synthase, brain0202
Nitric oxide synthase, inducible0101
Collagenase 30101
Nitric oxide synthase, inducible0101
Snq2p0001
Major prion protein0011
Calmodulin-10101
Alpha-2C adrenergic receptor0326
Trypanothione reductase0202
Sodium-dependent serotonin transporter0404
Pleiotropic ABC efflux transporter of multiple drugs0102
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Cytochrome P450 3A40101
Adenosine receptor A30112
Cytochrome P450 2C80101
Cytochrome P450 2D60101
D(3) dopamine receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Endothelin-1 receptor0112
5-hydroxytryptamine receptor 1B0213
Adenosine receptor A2a0112
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Cholecystokinin receptor type A0112
Cytochrome P450 2C190101
5-hydroxytryptamine receptor 70112
Mu-type opioid receptor0112
Vasopressin V1a receptor0112
Delta-type opioid receptor0112
Kappa-type opioid receptor0112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium/bile acid cotransporter0101
Nuclear receptor subfamily 2 group E member 10022
ERAP1 protein0001
ERAP2 protein0001
FAD-linked sulfhydryl oxidase ALR0001
leucyl-cystinyl aminopeptidase [Mus musculus]0001
Acetylcholinesterase0101
Glyceraldehyde-3-phosphate dehydrogenase0101
Amine oxidase [flavin-containing] A0101
Amine oxidase [flavin-containing] B0101
Sorbitol dehydrogenase0101
Transcription factor p650001
Transient receptor potential cation channel subfamily A member 10011
Chain A, CARBONIC ANHYDRASE II0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Dihydrofolate reductase0202
Myeloperoxidase0101
Stromelysin-10101
Indoleamine 2,3-dioxygenase 10102
Tryptophan 2,3-dioxygenase0102
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Monocarboxylate transporter 100001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]