Epicondylitis, Lateral Humeral

Synonym
Epicondylitis, Lateral Humeral
Lateral Epicondylitis

Excerpt	Reference
"Lateral epicondylitis is a common complaint, with an annual incidence between 1% and 3% in the general population."	( Adèr, HJ; Assendelft, WJ; Bouter, LM; Korthals-de Bos, IB; Rutten-van Mölken, MP; Smidt, N; van der Windt, DA; van Tulder, MW, 2004)
"Lateral epicondylitis is a painful condition responsible for loss of function and sick leave for long periods of time."	( Brage, S; Holmedal, Ø; Lindbaek, M; Olaussen, M, 2009)
"Lateral epicondylitis is a common orthopedic problem."	( Othman, AM, 2011)
"Lateral epicondylitis is a common musculoskeletal disorder characterized by the decreased grip and upper limb strength and pain in the lateral aspect of the elbow joint."	( Lan, Q; Lin, X; Wan, Q; Zhi, F, 2022)
"Lateral epicondylitis is a common condition with a prolonged course that can be frustrating for patients."	( Malhotra, G, 2023)

Excerpt	Reference
"In a prospective randomized study of lateral epicondylitis, 120 patients were treated with 2 mL lidocaine (Group A, n=60) or 1 mL lidocaine combined with 1 mL triamcinolone (Group B, n=60)."	( Altay, T; Günal, I; Oztürk, H, 2002)
"Eighty-three patients with unilateral lateral epicondylitis identified by the treating physical therapists."	( Davis, AM; Jaglal, SB; Tomlinson, G; Verrier, MC; Waugh, EJ, 2004)
"Arthroscopic treatment of lateral epicondylitis gives more favorable results than percutaneous tenotomy."	( Othman, AM, 2011)
"PRP therapy for lateral epicondylitis can improve extensor tendon morphology."	( Adler, RS; Chang, A; Chaudhury, S; Cordasco, F; de La Lama, M; Fealy, S; Gulotta, LV; Hannafin, J; Moley, P; Skonieczki, B, 2013)
"50 consecutive patients of untreated lateral epicondylitis were enrolled."	( Bachhal, V; Banshiwal, RC; Gaury, Y; Jindal, N; Lamoria, R, 2013)
"A total of 61 patients (16 with lateral epicondylitis, 14 with patellar tendinopathy, 15 with insertional Achilles tendinopathy, and 16 with plantar fasciitis) were each administered a single injection of HA (up to 2."	( Ishizaki, Y; Isomoto, S; Kumai, T; Muneta, T; Samoto, N; Shiraishi, M; Sugimoto, K; Takakura, Y; Tanaka, Y; Tsuchiya, A, 2014)
"In the treatment of Lateral Epicondylitis (LE) no single intervention concerning injection therapies has been proven to be the most effective with regard to pain reduction."	( Beumer, A; Eygendaal, D; Frings-Dresen, MHW; Gerritsma-Bleeker, CLE; Keijsers, R; Koenraadt, KLM; Kuijer, PPFM; van den Bekerom, MPJ, 2019)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	35 (15.70)	23.3326
1990's	37 (16.59)	12.5806
2000's	52 (23.32)	18.1394
2010's	79 (35.43)	28.8240
2020's	20 (8.97)	9.53

Drug	Relationship Strength	Studies	Trials
dimethyl sulfoxide	medium	2	2
glycerol	low	1	0
nitrates	low	1	0
acetaminophen	low	1	0
bupivacaine	medium	4	3
ciprofloxacin	low	2	0
diclofenac	medium	5	4
diflunisal	medium	1	1
flurbiprofen	medium	1	1
guanfacine	low	1	0
ibuprofen	low	1	0
lidocaine	medium	24	16
indomethacin	medium	3	1
midazolam	low	1	0
nitroglycerin	medium	7	2
oxybutynin	medium	2	1
pamidronate	low	1	0
prilocaine	medium	1	1
procaine	medium	2	1
proglumetacin	medium	1	1
propranolol	low	1	0
hydrocortisone acetate	low	1	0
prednisolone	medium	3	1
prednisolone acetate	medium	1	1
prednisone	medium	1	1
methylprednisolone acetate	medium	7	3
tetrabenazine	low	1	0
carbostyril	low	1	0
perflutren	low	1	0
triamcinolone acetonide	medium	15	4
methylprednisolone	medium	22	8
betamethasone	medium	7	4
technetium	low	1	0
helium	medium	1	1
holmium	low	1	0
ozone	low	1	0
trolamine salicylate	low	17	0
fluorides	low	1	0
triamcinolone	medium	24	16
chloroprene	low	1	0
glutamic acid	low	1	0
substance p	low	6	0
pefloxacin	low	2	0
fomesafen	low	1	0
isothiocyanic acid	low	1	0
firefly luciferin	low	1	0
imipenem, anhydrous	low	2	0
technetium tc 99m hydroxymethylene diphosphonate	low	1	0
betamethasone-17,21-dipropionate	low	1	0
naproxen	medium	7	6
cortisone	medium	11	2
polidocanol	medium	7	2
capsaicin	low	1	0
dinoprostone	low	1	0
neurokinin a	low	2	0
arsenic	low	1	0
gallium	medium	2	1
cilastatin	low	1	0
gadolinium dtpa	medium	2	1
neuropeptide y	low	3	0
vendex	low	7	0
sodium salicylate	medium	1	1
cilastatin, imipenem drug combination	low	1	0
sodium pertechnetate tc 99m	medium	1	1
interleukin-8	low	1	0
vasoactive intestinal peptide	low	1	0
salicylates	medium	1	1
piroxicam	medium	3	2
mobiflex	medium	1	1
hyaluronoglucosaminidase	low	1	0
technetium tc 99m medronate	low	2	0
sodium morrhuate	medium	4	2
chondroitin sulfates	medium	1	1

Protein Targets (674)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	13	0	0	13
ATAD5 protein, partial	7	0	0	7
GLS protein	11	0	0	11
Microtubule-associated protein tau	4	0	0	4
Smad3	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	10	0	0	10
thyroid stimulating hormone receptor	6	0	0	6
nuclear receptor subfamily 1, group I, member 3	8	0	0	8
progesterone receptor	13	0	0	13
EWS/FLI fusion protein	8	0	0	8
retinoic acid nuclear receptor alpha variant 1	15	0	0	15
retinoid X nuclear receptor alpha	14	0	0	14
estrogen-related nuclear receptor alpha	17	0	0	17
estrogen nuclear receptor alpha	27	0	0	27
peroxisome proliferator activated receptor gamma	11	0	0	11
aryl hydrocarbon receptor	9	0	0	9
chromobox protein homolog 1	11	0	0	11
thyroid hormone receptor beta isoform 2	12	0	0	12
peripheral myelin protein 22	7	0	0	7
cytochrome P450 3A4 isoform 1	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	7	3	1	11
ATP-binding cassette sub-family C member 3	0	17	0	17
Multidrug resistance-associated protein 4	0	17	0	18
Solute carrier family 22 member 6	0	7	0	7
Carbonic anhydrase 12	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	3
Bile salt export pump	0	3	0	3
Voltage-dependent calcium channel gamma-2 subunit	6	0	0	6
Bile salt export pump	0	26	0	26
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	10	0	11
Carbonic anhydrase 2	0	10	0	11
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	3	0	4
Prostaglandin G/H synthase 1	0	11	0	12
Carbonic anhydrase 3	0	2	0	2
Cytochrome P450 3A4	0	6	1	7
Cytochrome P450 2D6	0	4	0	4
Cytochrome P450 2C9	0	12	0	13
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	7	3	1	11
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	7	3	1	11
Gamma-aminobutyric acid receptor subunit gamma-2	7	3	1	11
UDP-glucuronosyltransferase 1-6	0	3	0	4
Glutamate receptor 2	6	2	2	10
Gamma-aminobutyric acid receptor subunit alpha-5	7	3	1	11
Gamma-aminobutyric acid receptor subunit alpha-3	7	3	1	11
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	4
Carbonic anhydrase 4	0	4	0	4
Prostaglandin G/H synthase 1	0	13	0	13
Carbonic anhydrase 6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	7	3	1	11
Gamma-aminobutyric acid receptor subunit alpha-2	7	3	1	11
Gamma-aminobutyric acid receptor subunit alpha-4	7	3	1	11
Gamma-aminobutyric acid receptor subunit gamma-3	7	3	1	11
Gamma-aminobutyric acid receptor subunit alpha-6	7	3	1	11
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Prostaglandin G/H synthase 2	0	11	1	13
Carbonic anhydrase 7	0	2	0	2
Nuclear receptor ROR-gamma	5	0	0	5
Cytochrome P450 2J2	0	10	0	10
Gamma-aminobutyric acid receptor subunit alpha-1	7	4	1	12
Gamma-aminobutyric acid receptor subunit beta-3	7	3	1	11
Gamma-aminobutyric acid receptor subunit beta-2	7	3	1	11
Carbonic anhydrase 9	0	3	0	3
GABA theta subunit	7	3	1	11
Canalicular multispecific organic anion transporter 1	0	17	0	17
Carbonic anhydrase 15	0	3	0	3
Carbonic anhydrase 13	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	7	3	1	11
Carbonic anhydrase 14	0	2	0	2
Carbonic anhydrase 5B, mitochondrial	0	2	0	2
toxin B	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	11	0	0	11
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	8	0	0	8
Chain B, HADH2 protein	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	2	0	0	2
thioredoxin reductase	10	0	0	10
AR protein	24	0	0	24
hypothetical protein, conserved	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	8	0	0	8
glucocorticoid receptor [Homo sapiens]	17	0	0	17
cytochrome P450 2D6	8	0	0	8
glucocerebrosidase	3	0	0	3
peroxisome proliferator-activated receptor delta	8	0	0	8
Rac1 protein	0	0	1	1
IDH1	8	0	0	8
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
euchromatic histone-lysine N-methyltransferase 2	19	0	0	19
Bloom syndrome protein isoform 1	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
DNA polymerase iota isoform a (long)	5	0	0	5
DNA polymerase kappa isoform 1	6	0	0	6
muscarinic acetylcholine receptor M1	6	0	0	6
lethal factor (plasmid)	2	0	0	2
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	6	0	7
Prostaglandin G/H synthase 2	0	4	0	5
Epidermal growth factor receptor	0	3	0	3
Fatty acid-binding protein, liver	0	6	0	6
Integrin beta-3	0	1	1	2
Myeloperoxidase	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	0	1	1	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	4	0	4
Adenosine receptor A2a	0	4	0	4
Substance-P receptor	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	7	0	7
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	5	1	6
Sigma non-opioid intracellular receptor 1	0	1	1	2
pregnane X receptor	3	0	0	3
GLI family zinc finger 3	14	0	0	14
farnesoid X nuclear receptor	7	0	0	7
pregnane X nuclear receptor	15	0	0	15
vitamin D (1,25- dihydroxyvitamin D3) receptor	14	0	0	14
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	13	0	0	13
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
thyroid hormone receptor beta isoform a	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	9	0	0	9
galanin receptor type 3	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	15	0	0	15
Glucocorticoid receptor	0	14	2	21
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
ORF73	0	0	1	1
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
Potassium channel subfamily K member 9	0	1	0	1
15-lipoxygenase, partial	2	0	0	2
phosphopantetheinyl transferase	7	0	0	7
TDP1 protein	19	0	0	19
estrogen receptor 2 (ER beta)	7	0	0	7
67.9K protein	3	0	0	3
mitogen-activated protein kinase 1	4	0	0	4
nuclear receptor ROR-gamma isoform 1	8	0	0	8
survival motor neuron protein isoform d	2	0	0	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
lamin isoform A-delta10	13	0	0	13
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
Lysine-specific histone demethylase 1A	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Cannabinoid receptor 1	0	3	1	5
Acetylcholinesterase	0	2	0	2
Cannabinoid receptor 2	0	3	1	5
Spike glycoprotein	6	0	0	6
D(2) dopamine receptor	0	0	2	2
Inositol monophosphatase 1	1	0	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Transient receptor potential cation channel subfamily V member 2	0	0	1	1
ATP-dependent phosphofructokinase	3	0	0	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
Chain A, serum paraoxonase	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Beta-2 adrenergic receptor	0	3	0	4
Beta-1 adrenergic receptor	0	3	1	5
Dipeptidase 1	0	1	0	1
Beta-3 adrenergic receptor	0	3	0	3
Solute carrier family 22 member 6	0	10	0	11
Solute carrier family 22 member 8	0	5	0	6
Solute carrier family 22 member 8	0	1	0	1
Chain A, Cruzipain	3	0	0	3
cytochrome P450 2C9 precursor	5	0	0	5
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	1	0	3
DNA gyrase subunit B	0	1	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	1	0	4
DNA gyrase subunit A	0	1	0	2
Cytochrome P450 2C19	0	3	0	3
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	5	0	0	5
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
Potassium voltage-gated channel subfamily H member 2	0	5	0	6
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	1	0	1
endonuclease IV	1	0	0	1
dopamine D1 receptor	1	0	0	1
regulator of G-protein signaling 4	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
peripheral myelin protein 22 isoform 1	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
heat shock protein beta-1	7	0	0	7
flap endonuclease 1	4	0	0	4
geminin	15	0	0	15
M-phase phosphoprotein 8	2	0	0	2
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	3	0	3
TAR DNA-binding protein 43	6	0	0	6
Multidrug and toxin extrusion protein 1	0	4	0	4
Aldo-keto reductase family 1 member B10	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	2
Dihydrofolate reductase	0	4	0	4
Cytochrome c oxidase subunit 2	0	2	0	2
Transthyretin	0	1	3	8
Albumin	0	7	5	12
Interleukin-8	0	3	0	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	4	1	5
Aldo-keto reductase family 1 member B1	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	2	0	5
UDP-glucuronosyltransferase 1A4	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Prostaglandin G/H synthase 2	0	5	0	7
UDP-glucuronosyltransferase 1A3	0	0	0	3
UDP-glucuronosyltransferase 2B10	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Prostaglandin G/H synthase 2	0	4	0	5
Prostaglandin G/H synthase 1	0	6	0	8
Carbonic anhydrase 4	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Luciferase	11	0	0	11
electroneutral potassium-chloride cotransporter KCC2	0	0	1	1
SMAD family member 2	9	0	0	9
SMAD family member 3	9	0	0	9
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	9	0	0	9
G	9	0	0	9
activating transcription factor 6	5	0	0	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
Interferon beta	13	0	0	13
HLA class I histocompatibility antigen, B alpha chain	9	0	0	9
Cellular tumor antigen p53	12	0	0	12
High mobility group protein B1	0	0	1	1
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase	0	2	0	2
Inositol hexakisphosphate kinase 1	9	0	0	9
cytochrome P450 2C9, partial	9	0	0	9
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
thyroid stimulating hormone receptor	3	0	0	3
prostaglandin E2 receptor EP2 subtype	1	0	0	1
vitamin D3 receptor isoform VDRA	5	0	0	5
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	1	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
Fatty-acid amide hydrolase 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
L-lactate dehydrogenase A chain	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Glutamate receptor 1	0	2	2	4
Glutamate receptor 3	0	2	2	4
Glutamate receptor 4	0	2	2	4
Cannabinoid receptor 1	0	2	1	3
Glycine receptor subunit alpha-1	0	0	2	2
D(3) dopamine receptor	0	2	1	3
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 2	0	1	1	2
N-arachidonyl glycine receptor	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
ATPase family AAA domain-containing protein 5	6	0	0	6
Monoglyceride lipase	0	1	0	1
Ataxin-2	8	0	0	8
Monoacylglycerol lipase ABHD6	0	1	0	1
Cannabinoid receptor 2	0	2	0	2
G-protein coupled receptor 55	0	1	1	2
G-protein coupled receptor 35	0	1	1	2
Carbonic anhydrase	0	2	0	2
glp-1 receptor, partial	4	0	0	4
PPM1D protein	3	0	0	3
caspase 7, apoptosis-related cysteine protease	3	0	0	3
caspase-3	3	0	0	3
histone deacetylase 9 isoform 3	1	0	0	1
Acid-sensing ion channel 3	0	2	0	2
Amyloid-beta precursor protein	0	2	0	2
Aldo-keto reductase family 1 member C4	0	3	0	3
Aldo-keto reductase family 1 member C3	0	5	0	5
Aldo-keto reductase family 1 member C2	0	3	0	3
Acid-sensing ion channel 1	0	2	0	2
Aldo-keto reductase family 1 member C1	0	3	0	3
hypoxia-inducible factor 1 alpha subunit	7	0	0	7
Histone H2A.x	1	0	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	4	2	6
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	4	2	6
Glutamate receptor ionotropic, NMDA 2B	0	4	2	6
Glutamate receptor ionotropic, NMDA 2C	0	4	2	6
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	4	2	6
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	4	2	6
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	4	2	6
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
cytochrome P450 2D6 isoform 1	4	0	0	4
cytochrome P450 2C19 precursor	2	0	0	2
D(1A) dopamine receptor	3	0	0	3
5-hydroxytryptamine receptor 4	0	4	0	4
Alpha-2A adrenergic receptor	0	3	2	6
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-2B adrenergic receptor	0	2	1	4
Alpha-2C adrenergic receptor	0	3	2	6
5-hydroxytryptamine receptor 2A	0	4	1	5
5-hydroxytryptamine receptor 2C	0	4	1	5
5-hydroxytryptamine receptor 2B	0	6	1	7
Nischarin	0	1	0	1
Chain A, Beta-lactamase	3	0	0	3
transcriptional regulator ERG isoform 3	3	0	0	3
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
USP1 protein, partial	4	0	0	4
NFKB1 protein, partial	3	0	0	3
nonstructural protein 1	3	0	0	3
arylsulfatase A	6	0	0	6
muscleblind-like protein 1 isoform 1	4	0	0	4
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Albumin	0	1	0	1
Albumin	0	0	1	1
Cholinesterase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	8
Prostaglandin G/H synthase 1	0	2	0	2
Caspase-1	0	3	0	4
Caspase-3	0	3	0	3
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Caspase-4	0	3	0	3
Caspase-5	0	3	0	3
Caspase-9	0	3	0	3
Mu-type opioid receptor	0	3	1	4
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	1	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Kappa-type opioid receptor	0	2	1	4
Beta-lactamase TEM	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
ras-related protein Rab-9A	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
neuropeptide S receptor isoform A	1	0	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Phospholipase A2, major isoenzyme	0	1	0	1
Procathepsin L	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Androgen receptor	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
C-X-C chemokine receptor type 3	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	2	0	2
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
acetylcholinesterase	2	0	0	2
Androgen receptor	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Translocator protein	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
lysosomal alpha-glucosidase preproprotein	1	0	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M2	0	2	0	2
Histidine decarboxylase	0	0	1	1
D(3) dopamine receptor	0	2	0	2
Adenosine receptor A1	0	1	0	1
Delta-type opioid receptor	0	2	1	4
Delta-type opioid receptor	0	2	2	4
Kappa-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	3	2	5
Kappa-type opioid receptor	0	1	2	3
Mu-type opioid receptor	0	3	2	6
Delta-type opioid receptor	0	3	2	6
Kappa-type opioid receptor	0	3	3	7
Mu-type opioid receptor	0	1	0	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Beta-2 adrenergic receptor	0	2	1	4
UDP-glucuronosyltransferase 1A8	0	0	0	1
Hormone-sensitive lipase	0	1	0	1
Neuromedin-K receptor	0	0	2	2
Substance-K receptor	0	1	2	3
Substance-K receptor	0	4	0	5
Substance-P receptor	0	3	1	4
Neuromedin-K receptor	0	2	2	4
Substance-K receptor	0	2	0	2
Substance-K receptor	0	2	0	2
Substance-K receptor	0	1	0	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Sodium/iodide cotransporter	0	1	0	1
Fumarate hydratase	1	0	0	1
polyprotein	1	0	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	3	2	6
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M1	0	3	1	5
Muscarinic acetylcholine receptor M3	0	3	1	4
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Muscarinic acetylcholine receptor	0	0	1	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Alpha-synuclein	1	0	0	1
huntingtin isoform 2	1	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
thioredoxin glutathione reductase	2	0	0	2
Beta-1 adrenergic receptor	0	1	1	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 1A	0	1	0	1
Adenosine receptor A3	0	1	1	2
Cytochrome P450 2C8	0	1	0	1
Beta-3 adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	1	2
5-hydroxytryptamine receptor 1A	0	2	1	4
Alpha-2B adrenergic receptor	0	0	1	1
D(1A) dopamine receptor	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Alpha-2C adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	0	1	1
Alpha-1D adrenergic receptor	0	1	1	2
Alpha-1D adrenergic receptor	0	0	1	2
Endothelin-1 receptor	0	1	1	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 1B	0	2	0	2
Adenosine receptor A2a	0	1	1	2
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Cholecystokinin receptor type A	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	2	4
Alpha-1B adrenergic receptor	0	0	1	2
Vasopressin V1a receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	1	1	2
5-hydroxytryptamine receptor 6	0	2	1	3
5-hydroxytryptamine receptor 7	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Substance-P receptor	0	2	0	2
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
DNA polymerase beta	1	0	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Epicondylitis, Lateral Humeral

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (223)

Protein Targets (674)

Epicondylitis, Lateral Humeral

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (223)

Drugs Studied (84)

Protein Targets (674)