Page last updated: 2024-09-27

Neoplasms, Plasma Cell

Neoplasms associated with a proliferation of a single clone of PLASMA CELLS and characterized by the secretion of PARAPROTEINS.

Synonyms(2)

Synonym
Neoplasms, Plasma Cell
Plasma Cell Neoplasms

Research Excerpts

Overview

ExcerptReference
"Plasma cell neoplasms are characterized by the proliferation of a single clone of plasma cells with production of a monoclonal immunoglobulin."( Andrade, BAB; Brandão, TB; Cáceres, CVBL; Carlos, R; Carvalho, MGF; de Almeida, OP; Fonseca, FP; González-Arriagada, WA; Lopes, MA; Mesquita, RA; Pedraza, RM; Pereira, J; Pires, FR; Pontes, FSC; Pontes, HAR; Prado-Ribeiro, AC; Romañach, MJ; Santos-Silva, AR; Silva, WGD; Soares, CD; Souza, LL; Vargas, PA, 2021)
"Plasma cell neoplasms are aggressive tumours with a poor prognosis and involvement of the jaws may be the first complaint of the patient."( Andrade, BAB; Brandão, TB; Cáceres, CVBL; Carlos, R; Carvalho, MGF; de Almeida, OP; Fonseca, FP; González-Arriagada, WA; Lopes, MA; Mesquita, RA; Pedraza, RM; Pereira, J; Pires, FR; Pontes, FSC; Pontes, HAR; Prado-Ribeiro, AC; Romañach, MJ; Santos-Silva, AR; Silva, WGD; Soares, CD; Souza, LL; Vargas, PA, 2021)

Research

Studies (97)

TimeframeStudies, This Condition (%)All Conditions %
pre-199053 (54.64)23.3326
1990's0 (0.00)12.5806
2000's4 (4.12)18.1394
2010's24 (24.74)28.8240
2020's16 (16.49)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low10
choline0low20
glycine0low10
purine0low10
dimethoate0low10
mechlorethamine0low50
metformin0low10
pentamidine0low20
thalidomide0medium72
thiotepa0low10
urethane0low80
prednisolone0low30
prednisone0low70
serine0low10
methionine0low20
pyrazines0low30
reticulin0low10
cadmium sulfate0low10
propiconazole0low20
acridine orange0low10
plerixafor0low10
fluorodeoxyglucose f180low50
yttrium radioisotopes0low10
tadalafil0low10
imatinib mesylate0low10
methotrexate0low10
pomalidomide0medium32
lenalidomide0medium51
cortisone0low10
bortezomib0low80
fluorocholine0low10
inositol 3-phosphate0low20
diethylstilbestrol0low10
azaserine0low20
melphalan0low50
stilbenes0low20
mercaptopurine0low20
methylthiouracil0low10
thiouracil0low10
17-ketosteroids0low10
phenylephrine hydrochloride0low20
stilbamidine0low30
phosphorus0low20
radium0low10
mocetinostat0low10
carfilzomib0low10
jaw0low20
carbon-11 methionine0low10
pci 327650low10
ixazomib0low10
piperidines0low20
interleukin-80medium11
abt-1990low10
cyclin d10low20
eye0low20
phosphorus radioisotopes0low10

Protein Targets (957)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
EWS/FLI fusion protein170017
Apoptosis regulator Bcl-20224
Spike glycoprotein9009
Bcl-2-like protein 10202
Induced myeloid leukemia cell differentiation protein Mcl-10202
Aspartyl/asparaginyl beta-hydroxylase0101
Bcl-2-related protein A10101
Bcl-2-like protein 20101
Bcl2-associated agonist of cell death 0101
Telomerase reverse transcriptase0101
Amyloid-beta precursor protein0101
Reverse transcriptase/RNaseH 0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE5005
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
RAR-related orphan receptor gamma150015
TDP1 protein190019
AR protein190019
nuclear receptor subfamily 1, group I, member 3140014
cytochrome P450 family 3 subfamily A polypeptide 4120012
glucocorticoid receptor [Homo sapiens]150015
estrogen-related nuclear receptor alpha190019
pregnane X nuclear receptor150015
estrogen nuclear receptor alpha230023
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a140014
nuclear factor erythroid 2-related factor 2 isoform 25005
heat shock protein beta-17007
importin subunit beta-1 isoform 14004
snurportin-14004
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 12002
lamin isoform A-delta106006
Voltage-dependent calcium channel gamma-2 subunit120012
Bile salt export pump017017
Cyclin-dependent kinase 10112
Heat shock protein HSP 90-beta0101
Glutamate receptor 2120012
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 436006
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 59009
Ataxin-29009
Chain A, JmjC domain-containing histone demethylation protein 3A3003
apical membrane antigen 1, AMA12002
farnesoid X nuclear receptor120012
cytochrome P450 2D69009
peroxisome proliferator activated receptor gamma100010
vitamin D3 receptor isoform VDRA7007
nuclear factor erythroid 2-related factor 2 isoform 1150015
geminin120012
Cellular tumor antigen p53140014
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110303
Fumarate hydratase8008
PPM1D protein7007
caspase 7, apoptosis-related cysteine protease4004
estrogen receptor 2 (ER beta)8008
progesterone receptor120012
retinoic acid nuclear receptor alpha variant 1150015
retinoid X nuclear receptor alpha150015
polyprotein8008
peroxisome proliferator-activated receptor delta9009
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
caspase-34004
nuclear receptor subfamily 1, group I, member 22002
Histone H2A.x7007
Caspase-73003
caspase-33003
thyroid hormone receptor beta isoform 29009
26S proteasome non-ATPase regulatory subunit 110202
26S proteasome non-ATPase regulatory subunit 120202
26S proteasome non-ATPase regulatory subunit 140202
Proteasome subunit alpha type-70303
Histone deacetylase 30303
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010011
26S proteasome non-ATPase regulatory subunit 30202
Carbonic anhydrase 120202
Prothrombin0101
Chymotrypsinogen A0202
Carbonic anhydrase 10404
Carbonic anhydrase 20415
Interferon beta140014
Carbonic anhydrase 30202
Cathepsin B0202
Neutrophil elastase0101
Cathepsin G0303
Lysosomal protective protein0202
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0202
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10304
Carbonic anhydrase 40202
Carbonic anhydrase 60202
Chymase0101
Proteasome subunit alpha type-10303
Proteasome subunit alpha type-20303
Proteasome subunit alpha type-30303
Proteasome subunit alpha type-40303
Proteasome subunit beta type-80303
Proteasome subunit beta type-80101
Proteasome subunit beta type-90303
Proteasome subunit alpha type-50303
Proteasome subunit beta type-40303
Proteasome subunit beta type-60303
Proteasome subunit beta type-50405
Carbonic anhydrase 5A, mitochondrial0202
26S proteasome regulatory subunit 70202
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100303
Carbonic anhydrase 70202
26S proteasome regulatory subunit 6B0213
26S proteasome non-ATPase regulatory subunit 80202
Proteasome subunit beta type-30303
Proteasome subunit beta type-20304
26S proteasome non-ATPase regulatory subunit 70202
26S proteasome non-ATPase regulatory subunit 40202
26S proteasome complex subunit SEM10202
Proteasome subunit alpha type-60303
26S proteasome regulatory subunit 40202
26S proteasome regulatory subunit 80202
26S proteasome regulatory subunit 10B0202
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20202
Histone deacetylase 10303
26S proteasome non-ATPase regulatory subunit 60202
Proteasomal ubiquitin receptor ADRM10202
Carbonic anhydrase 90202
ATP-dependent Clp protease proteolytic subunit0224
Carbonic anhydrase 130101
NACHT, LRR and PYD domains-containing protein 3 0202
Proteasome subunit alpha-type 80303
Histone deacetylase 20303
Canalicular multispecific organic anion transporter 1010010
Proteasome subunit beta type-70303
26S proteasome non-ATPase regulatory subunit 10202
Carbonic anhydrase 150202
Histone deacetylase 80202
Histone deacetylase 60202
Carbonic anhydrase 140202
26S proteasome non-ATPase regulatory subunit 130202
Carbonic anhydrase 5B, mitochondrial0202
acetylcholinesterase6006
GLI family zinc finger 3130013
Proteasome subunit beta type-20101
Proteasome subunit beta type-10101
Glutathione S-transferase omega-10101
Potassium voltage-gated channel subfamily H member 20707
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
euchromatic histone-lysine N-methyltransferase 2100010
muscarinic acetylcholine receptor M13003
Solute carrier family 22 member 10102
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0203
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-41102
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-21102
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Acetylcholinesterase0303
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Solute carrier family 22 member 10103
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20102
ATP-dependent phosphofructokinase3003
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
endonuclease IV1001
dopamine D1 receptor2002
thioredoxin reductase8008
pregnane X receptor3003
GLS protein3003
aldehyde dehydrogenase 1 family, member A19009
regulator of G-protein signaling 43003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
v-jun sarcoma virus 17 oncogene homolog (avian)5005
peripheral myelin protein 22 isoform 11001
atrial natriuretic peptide receptor 1 precursor1001
chromobox protein homolog 15005
flap endonuclease 12002
survival motor neuron protein isoform d8008
cytochrome P450 3A4 isoform 14004
M-phase phosphoprotein 82002
Gamma-aminobutyric acid receptor subunit pi4004
Glucocorticoid receptor08215
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10808
Corticosteroid-binding globulin0202
Gamma-aminobutyric acid receptor subunit beta-14004
Gamma-aminobutyric acid receptor subunit delta4004
Gamma-aminobutyric acid receptor subunit gamma-24004
Gamma-aminobutyric acid receptor subunit alpha-54004
Gamma-aminobutyric acid receptor subunit alpha-34004
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Gamma-aminobutyric acid receptor subunit gamma-14004
Gamma-aminobutyric acid receptor subunit alpha-24004
Glycine receptor subunit alpha-30808
Gamma-aminobutyric acid receptor subunit alpha-44004
Gamma-aminobutyric acid receptor subunit gamma-34004
Gamma-aminobutyric acid receptor subunit alpha-64004
Gamma-aminobutyric acid receptor subunit alpha-14004
Gamma-aminobutyric acid receptor subunit beta-34004
Gamma-aminobutyric acid receptor subunit beta-24004
Potassium voltage-gated channel subfamily A member 10011
GABA theta subunit4004
Multidrug and toxin extrusion protein 10303
Gamma-aminobutyric acid receptor subunit epsilon4004
Chain A, Ferritin light chain4004
Luciferase5005
interleukin 81001
glp-1 receptor, partial5005
15-lipoxygenase, partial4004
hypoxia-inducible factor 1 alpha subunit4004
ATAD5 protein, partial3003
USP1 protein, partial5005
Microtubule-associated protein tau4004
Smad33003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
thyroid stimulating hormone receptor1001
G7007
67.9K protein3003
IDH16006
thyroid stimulating hormone receptor5005
activating transcription factor 62002
cellular tumor antigen p53 isoform a4004
thyroid hormone receptor beta isoform a3003
potassium voltage-gated channel subfamily H member 2 isoform d2002
mitogen-activated protein kinase 12002
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
serine/threonine-protein kinase PLK12002
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
nuclear receptor ROR-gamma isoform 14004
peripheral myelin protein 224004
high affinity choline transporter 1 isoform a0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
lethal factor (plasmid)2002
neuropeptide S receptor isoform A1001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
5-hydroxytryptamine receptor 40404
Nuclear receptor subfamily 1 group I member 20101
HLA class I histocompatibility antigen, B alpha chain 7007
Estrogen receptor0415
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Integrin beta-33003
Tyrosine-protein kinase Fyn0213
Aldo-keto reductase family 1 member B10404
Integrin alpha-IIb3003
Beta-1 adrenergic receptor0202
Alpha-2A adrenergic receptor0404
Polyunsaturated fatty acid 5-lipoxygenase0101
Adenosine receptor A30202
Muscarinic acetylcholine receptor M10202
Polyunsaturated fatty acid lipoxygenase ALOX150101
D(2) dopamine receptor0202
Androgen receptor0202
Alpha-1B adrenergic receptor0202
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Muscarinic acetylcholine receptor M30202
Substance-K receptor0202
D(1A) dopamine receptor0202
Prostaglandin G/H synthase 10303
Sodium-dependent noradrenaline transporter 0404
Thromboxane-A synthase 0101
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
Adenosine receptor A2a0202
Adenosine receptor A10202
Sodium-dependent serotonin transporter0202
Mu-type opioid receptor0202
D(3) dopamine receptor0404
Vasopressin V1a receptor0202
Alpha-synuclein1001
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0202
Histamine H2 receptor2002
5-hydroxytryptamine receptor 60202
Nuclear receptor ROR-gamma3003
Estrogen-related receptor gamma0011
Disintegrin and metalloproteinase domain-containing protein 171001
Inositol monophosphatase 11001
Sodium-dependent dopamine transporter 0404
Aldehyde oxidase0101
UDP-glucose 4-epimerase0101
Mitogen-activated protein kinase 140112
Inositol hexakisphosphate kinase 17007
Estrogen receptor beta0415
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Cysteinyl leukotriene receptor 10202
cytochrome P450 2C9, partial7007
phosphopantetheinyl transferase8008
aryl hydrocarbon receptor9009
polyadenylate-binding protein 10101
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Glutamate receptor ionotropic, NMDA 1 0213
Sodium- and chloride-dependent glycine transporter 10101
Glutamate receptor ionotropic, NMDA 2A 0213
Glutamate receptor ionotropic, NMDA 2B0213
Glutamate receptor ionotropic, NMDA 2C0213
Large neutral amino acids transporter small subunit 10202
Glutamate receptor ionotropic, NMDA 2D0213
Proton-coupled amino acid transporter 10202
Glutamate receptor ionotropic, NMDA 3B0213
Serine racemase0101
Olfactory receptor 51E20011
Glutamate receptor ionotropic, NMDA 3A0213
Sodium- and chloride-dependent glycine transporter 20101
SMAD family member 22002
SMAD family member 32002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
serine/threonine-protein kinase mTOR isoform 11001
DNA polymerase iota isoform a (long)4004
DNA repair protein RAD52 homolog isoform a0001
Tyrosine-protein kinase ABL10136
Cytochrome P450 3A40406
Cytochrome P450 2C80103
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0024
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50001
Cereblon isoform 40404
Bromodomain-containing protein 40101
DNA-binding protein Ikaros0027
DNA damage-binding protein 10325
Protein cereblon06314
Zinc finger protein Aiolos0022
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
thioredoxin glutathione reductase3003
glucocerebrosidase1001
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Large neutral amino acids transporter small subunit 1 0101
Chain A, Beta-lactamase3003
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, 2-oxoglutarate Oxygenase5005
bromodomain adjacent to zinc finger domain 2B1001
hemoglobin subunit beta2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
transcriptional regulator ERG isoform 32002
histone acetyltransferase KAT2A isoform 15005
UDP-glucose 6-dehydrogenase0101
Solute carrier family 22 member 80001
Hypoxanthine-guanine phosphoribosyltransferase0001
UDP-glucose 6-dehydrogenase0101
Purine nucleoside phosphorylase0011
UDP-glucuronosyltransferase 1A1 0101
Dihydrofolate reductase0304
Dipeptidyl peptidase 40101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
Bloom syndrome protein isoform 14004
polyunsaturated fatty acid lipoxygenase ALOX121001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
DNA polymerase kappa isoform 12002
muscleblind-like protein 1 isoform 11001
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0202
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20123
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60102
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80102
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Cytochrome P450 2D60303
Integrin alpha-40101
Cytochrome P450 2C190304
Histone deacetylase 40101
Histone deacetylase 70101
Histone deacetylase 11 0101
Histone deacetylase 50101
Nuclear receptor corepressor 20101
tyrosine-protein kinase Yes1001
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Testosterone 17-beta-dehydrogenase 30101
Dynamin-like 120 kDa protein, mitochondrial0011
Putative nucleoside diphosphate kinase0011
Tyrosine-protein kinase JAK20202
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Solute carrier family 22 member 30202
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Epidermal growth factor receptor0224
Receptor tyrosine-protein kinase erbB-20112
High affinity nerve growth factor receptor0011
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Cytochrome P450 1A20202
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0112
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Macrophage colony-stimulating factor 1 receptor0101
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0112
Tyrosine-protein kinase Lyn0112
Proto-oncogene tyrosine-protein kinase receptor Ret0112
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0112
Platelet-derived growth factor receptor beta0112
Tyrosine-protein kinase Fgr0101
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cytochrome P450 2C9 0304
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
Proto-oncogene tyrosine-protein kinase Src0112
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Cytochrome P450 2B60203
Ephrin type-A receptor 10011
Receptor tyrosine-protein kinase erbB-30101
Multifunctional protein ADE20011
Nucleoside diphosphate kinase B0011
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10213
G1/S-specific cyclin-E10101
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Deoxycytidine kinase0011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20112
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20112
Receptor-type tyrosine-protein kinase FLT30213
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
TGF-beta receptor type-20011
Tyrosine-protein kinase CSK0112
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Tyrosine-protein kinase Tec0112
Tyrosine-protein kinase TXK0112
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0112
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0112
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Tyrosine-protein kinase Blk0112
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Cytoplasmic tyrosine-protein kinase BMX0213
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Tyrosine-protein kinase JAK30112
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10012
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0224
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Tyrosine-protein kinase ITK/TSK0112
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10012
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60112
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Serine/threonine-protein kinase 380011
Receptor tyrosine-protein kinase erbB-40112
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10112
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
MAP kinase-activated protein kinase 30011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Putative heat shock protein HSP 90-beta 20011
Rab-like protein 30011
Sigma intracellular receptor 20101
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10011
Nuclear receptor subfamily 4 group A member 30101
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0112
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Peroxiredoxin-like 2A0101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Platelet glycoprotein VI0101
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
Phenylalanine--tRNA ligase beta subunit0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20012
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Protein arginine N-methyltransferase 50202
Protein tyrosine phosphatase type IVA 30101
Coagulation factor X0101
Plasminogen0101
Urokinase-type plasminogen activator0101
Protein S100-B0112
Glyceraldehyde-3-phosphate dehydrogenase0101
Protein S100-B0011
Trypsin-10101
Acrosin0101
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
60 kDa heat shock protein, mitochondrial0101
Angiotensin-converting enzyme0202
Amiloride-sensitive amine oxidase [copper-containing]0101
Amine oxidase [flavin-containing] A0101
Diamine acetyltransferase 10101
10 kDa heat shock protein, mitochondrial0101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Protein tyrosine phosphatase type IVA 20101
60 kDa chaperonin 0101
Nuclear receptor subfamily 3 group C member 3 0202
10 kDa chaperonin 0101
Multidrug and toxin extrusion protein 20101
Protein tyrosine phosphatase type IVA 10101
Protein arginine N-methyltransferase 10303
Suppressor of tumorigenicity 14 protein0101
GALC protein2002
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
C-X-C chemokine receptor type 40101
Atypical chemokine receptor 30011
C-C chemokine receptor type 20101
C-X-C chemokine receptor type 40204
Programmed cell death protein 10101
E3 ubiquitin-protein ligase ZFP910001
Programmed cell death 1 ligand 10101
luciferase0001
Fatty acid-binding protein, liver0101
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Cytochrome P450 2J20101
nonstructural protein 11001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
heat shock protein HSP 90-alpha isoform 20001
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Solute carrier family 22 member 60101
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Albumin0101
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit beta-10001
Acetylcholinesterase0101
Pyruvate kinase PKM0011
Neutral amino acid transporter A0101
Cholinesterase0101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
RmtA0101
Histone-arginine methyltransferase CARM10101
Protein arginine N-methyltransferase 60101
histone deacetylase 9 isoform 31001
Tyrosinase0101
NAD(P)H dehydrogenase [quinone] 10001
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Phosphodiesterase 0101
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
cGMP-specific 3',5'-cyclic phosphodiesterase0112
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0213
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cystic fibrosis transmembrane conductance regulator0011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
Potassium voltage-gated channel subfamily E member 10101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Acetylcholinesterase0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Potassium voltage-gated channel subfamily KQT member 10101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Synaptic vesicular amine transporter0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Sodium channel protein type 5 subunit alpha0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0101
Nuclear receptor subfamily 2 group E member 10011
arylsulfatase A1001
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 20101
Cytochrome P450 2B10101
Taste receptor type 2 member 380012
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]