4,5,6,7-tetrabromo-2-azabenzimidazole and Scleroderma, Systemic studies

Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Research Excerpts

Excerpt	Relevance	Reference
"Casein kinase II (CK2) is a constitutively active serine/threonine protein kinase that plays a key role in cellular transformation and tumorigenesis."	5.42	Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis. ( Beyer, C; Dees, C; Distler, A; Distler, JH; Distler, O; Kreuter, A; Lin, NY; Palumbo, K; Schett, G; Susok, L; Zerr, P; Zhang, Y, 2015)
"Casein kinase II (CK2) is a constitutively active serine/threonine protein kinase that plays a key role in cellular transformation and tumorigenesis."	1.42	Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis. ( Beyer, C; Dees, C; Distler, A; Distler, JH; Distler, O; Kreuter, A; Lin, NY; Palumbo, K; Schett, G; Susok, L; Zerr, P; Zhang, Y, 2015)

Research

Studies (1)

Authors

Other Studies

1 other study available for 4,5,6,7-tetrabromo-2-azabenzimidazole and Scleroderma, Systemic

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Zhang, Y	1
Dees, C	1
Beyer, C	1
Lin, NY	1
Distler, A	1
Zerr, P	1
Palumbo, K	1
Susok, L	1
Kreuter, A	1
Distler, O	1
Schett, G	1
Distler, JH	1