4,5,6,7-tetrabromo-2-azabenzimidazole has been researched along with Disease Models, Animal in 4 studies
4,5,6,7-tetrabromobenzotriazole: a CK2 kinase inhibitor
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Casein kinase II (CK2) is a constitutively active serine/threonine protein kinase that plays a key role in cellular transformation and tumorigenesis." | 5.42 | Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis. ( Beyer, C; Dees, C; Distler, A; Distler, JH; Distler, O; Kreuter, A; Lin, NY; Palumbo, K; Schett, G; Susok, L; Zerr, P; Zhang, Y, 2015) |
| "Casein kinase II (CK2) is a constitutively active serine/threonine protein kinase that plays a key role in cellular transformation and tumorigenesis." | 1.42 | Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis. ( Beyer, C; Dees, C; Distler, A; Distler, JH; Distler, O; Kreuter, A; Lin, NY; Palumbo, K; Schett, G; Susok, L; Zerr, P; Zhang, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Zhang, Y | 1 |
| Dees, C | 1 |
| Beyer, C | 1 |
| Lin, NY | 1 |
| Distler, A | 1 |
| Zerr, P | 1 |
| Palumbo, K | 1 |
| Susok, L | 1 |
| Kreuter, A | 1 |
| Distler, O | 1 |
| Schett, G | 1 |
| Distler, JH | 1 |
| Lee, SW | 1 |
| Rho, JH | 1 |
| Lee, SY | 1 |
| Yoo, SH | 1 |
| Kim, HY | 1 |
| Chung, WT | 1 |
| Yoo, YH | 1 |
4 other studies available for 4,5,6,7-tetrabromo-2-azabenzimidazole and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.
Topics: Adult; Aged; Animals; Casein Kinase II; Disease Models, Animal; Female; Fibroblasts; Fibrosis; Human | 2015 |
Alpha B-Crystallin Protects Rat Articular Chondrocytes against Casein Kinase II Inhibition-Induced Apoptosis.
Topics: alpha-Crystallin B Chain; Animals; Apigenin; Apoptosis; Benzimidazoles; Cartilage, Articular; Casein | 2016 |