Page last updated: 2024-09-27

Chemo-Fog

The diminished or impaired mental and/or intellectual function associated with the chemical treatment of cancer.

Synonyms(7)

Synonym
Chemo-Fog
Chemobrain
Chemotherapy-Induced Cognitive Dysfunction
Chemotherapy-Induced Cognitive Impairment
Chemotherapy-Related Cognitive Impairment
Chemotherapy-Related Cognitive Dysfunction
Chemotherapy-Induced Cognitive Impairments

Research Excerpts

Overview

ExcerptReference
"Chemobrain is a well-established clinical syndrome that impairs patient's daily function, in particular attentiveness, coordination and multi-tasking."( Abdel-Maged, AE; Azab, SS; El-Derany, MO; Wahdan, SA, 2020)
"In fact, chemobrain is a deteriorating condition which adversely affects the lives of cancer survivors."( El-Derany, MO; Noureldein, MH, 2021)
"Chemobrain is one of the major side effects of chemotherapy; despite increased research, the mechanisms underlying chemotherapy-induced cognitive changes remain unknown."( Devi, B; Sahu, K; Singh, A; Singh, C; Singh, S, 2022)

Context

ExcerptReference
"Chemobrain has been identified by the National Cancer Institute as a poorly understood problem for which current management or treatment strategies are limited or ineffective."( Bedwell, AA; Dridi, H; Figueiredo, LL; Guise, TA; Kerley, Y; Liu, Y; Marks, AR; Meyer, JA; Miotto, MC; Mohammad, KS; Persohn, SC; Peters, JS; Reiken, S; She, Y; Sittenfeld, L; Soni, RK; Suresh, S; Territo, PR; Trivedi, T; Wedderburn-Pugh, K; Yuan, Q, 2023)

Actions

ExcerptReference
"Chemobrain affects up to 75% of cancer survivors, and there are no known therapeutic options for its treatment."( Aldubayan, MA; Alhowail, AH; Almami, IS; Alsaud, MM, 2023)

Treatment

ExcerptReference
"PLD may assist in preventing chemobrain after chemotherapy in patients with cancers."( Cui, J; Sheng, S; Tong, Y; Wang, K, 2020)
"The term "chemobrain" refers to the cognitive dysfunction that occurs after chemotherapy, and it is also known as chemotherapy-induced cognitive impairment or "chemofog"."( Aldubayan, M; Alhowail, AH, 2021)
"Cognitive deficits (chemobrain) and peripheral neuropathy occur in ∼75% of patients treated for cancer with chemotherapy and persist long-term in >30% of survivors."( Alexander, JF; Arroyo, LD; Blanco, E; Heijnen, CJ; Hörbelt, T; Kavelaars, A; Mahalingam, R; Schedlowski, M; Seua, AV; Wu, S, 2022)
"Long-term cognitive dysfunction, or "chemobrain", has been observed in cancer patients treated with chemotherapy."( Carvalho, F; Costa, VM; Dias-Carvalho, A; Fernandes, E; Guedes de Pinho, P; Margarida-Araújo, A; Pereira, SA; Reis-Mendes, A; Sá, SI; Sequeira, CO, 2023)

Research

Studies (43)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's0 (0.00)28.8240
2020's43 (100.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dimethyl sulfoxide0low10
melatonin0low20
berberine0low20
donepezil0low10
metformin0low20
mitoxantrone0low20
pioglitazone0low20
phenylethyl alcohol0low10
tyrosine0low10
cuprizone0low10
amiloride0low10
clemastine0low10
paclitaxel0low30
valsartan0low10
glucose, (beta-d)-isomer0low10
bexarotene0low10
nicotine0medium11
methotrexate0low10
carboplatin0low10
lithium chloride0low10
piplartine0low10
piperine0low10
stilbenes0low10
dinoprostone0low10
caffeic acid phenethyl ester0low10
rosmarinic acid0low10
levetiracetam0low10
istradefylline0low10
exudates0low10

Protein Targets (684)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, 2-oxoglutarate Oxygenase6006
acid sphingomyelinase3003
acetylcholinesterase2002
thioredoxin reductase5005
TDP1 protein120012
AR protein110011
aldehyde dehydrogenase 1 family, member A19009
thyroid stimulating hormone receptor5005
regulator of G-protein signaling 46006
glucocorticoid receptor [Homo sapiens]5005
estrogen nuclear receptor alpha130013
glucocerebrosidase2002
arylsulfatase A5005
alpha-galactosidase2002
euchromatic histone-lysine N-methyltransferase 2100010
Bloom syndrome protein isoform 17007
cytochrome P450 2D6 isoform 15005
lysosomal alpha-glucosidase preproprotein2002
cytochrome P450 2C19 precursor2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
thyroid hormone receptor beta isoform 27007
huntingtin isoform 22002
nuclear factor erythroid 2-related factor 2 isoform 19009
geminin110011
lamin isoform A-delta107007
Membrane primary amine oxidase 0101
Solute carrier family 22 member 1 0406
Bile salt export pump012012
Prothrombin0101
Coagulation factor X0101
Plasminogen0101
Urokinase-type plasminogen activator0202
Tissue-type plasminogen activator0202
Cationic trypsin0101
Coagulation factor XI0101
Plasma kallikrein0102
Vitamin K-dependent protein C0101
Cellular tumor antigen p537007
Urokinase-type plasminogen activator0202
Trypsin-10101
Trypsin-20101
Sodium/hydrogen exchanger 10101
Amine oxidase [flavin-containing] A0404
Sodium/hydrogen exchanger 10202
Sodium/hydrogen exchanger 30202
Adenosine receptor A2a0314
Trypsin-30101
Amiloride-sensitive sodium channel subunit alpha0101
5-hydroxytryptamine receptor 70202
Sodium/hydrogen exchanger 20202
Acid-sensing ion channel 10101
Potassium voltage-gated channel subfamily H member 20808
Sodium channel protein type 5 subunit alpha0101
Sodium/hydrogen exchanger 50202
Solute carrier family 22 member 10203
Solute carrier family 22 member 20202
Acid-sensing ion channel 30101
Sodium/hydrogen exchanger0101
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Fumarate hydratase4004
PPM1D protein3003
Microtubule-associated protein tau6006
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
EWS/FLI fusion protein8008
polyprotein4004
peripheral myelin protein 228008
survival motor neuron protein isoform d6006
cytochrome P450 3A4 isoform 18008
Gamma-aminobutyric acid receptor subunit pi8008
Telomerase reverse transcriptase0101
Acetylcholinesterase0303
Lysine-specific histone demethylase 1A0202
Interferon beta5005
Neuraminidase0101
Neuraminidase0101
Cholinesterase0404
Gamma-aminobutyric acid receptor subunit beta-18008
Tyrosine-protein phosphatase non-receptor type 10202
Gamma-aminobutyric acid receptor subunit delta8008
Gamma-aminobutyric acid receptor subunit gamma-28008
Gamma-aminobutyric acid receptor subunit alpha-58008
Gamma-aminobutyric acid receptor subunit alpha-38008
Acetylcholinesterase0426
Gamma-aminobutyric acid receptor subunit gamma-18008
Gamma-aminobutyric acid receptor subunit alpha-28008
Gamma-aminobutyric acid receptor subunit alpha-48008
Gamma-aminobutyric acid receptor subunit gamma-38008
Gamma-aminobutyric acid receptor subunit alpha-68008
Aldo-keto reductase family 1 member C30202
Prolyl endopeptidase0101
Aldo-keto reductase family 1 member C2 0202
Gamma-aminobutyric acid receptor subunit alpha-18008
Gamma-aminobutyric acid receptor subunit beta-38008
Gamma-aminobutyric acid receptor subunit beta-28008
Cholinesterase0303
Inositol monophosphatase 13003
Cytochrome P450 1B10404
GABA theta subunit8008
Gamma-aminobutyric acid receptor subunit epsilon8008
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Luciferase5005
hypoxia-inducible factor 1 alpha subunit2002
RAR-related orphan receptor gamma7007
SMAD family member 22002
USP1 protein, partial4004
SMAD family member 32002
GLI family zinc finger 38008
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)4004
nuclear receptor subfamily 1, group I, member 36006
progesterone receptor4004
cytochrome P450 family 3 subfamily A polypeptide 44004
retinoic acid nuclear receptor alpha variant 16006
retinoid X nuclear receptor alpha6006
estrogen-related nuclear receptor alpha7007
farnesoid X nuclear receptor5005
pregnane X nuclear receptor5005
G3003
peroxisome proliferator-activated receptor delta5005
peroxisome proliferator activated receptor gamma4004
vitamin D (1,25- dihydroxyvitamin D3) receptor4004
caspase-32002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a5005
thyroid stimulating hormone receptor3003
activating transcription factor 62002
thyrotropin-releasing hormone receptor1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
v-jun sarcoma virus 17 oncogene homolog (avian)1001
nuclear receptor subfamily 1, group I, member 22002
Histone H2A.x3003
Caspase-71001
vitamin D3 receptor isoform VDRA6006
caspase-31001
heat shock protein beta-11001
nuclear receptor ROR-gamma isoform 14004
histone acetyltransferase KAT2A isoform 15005
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010012
Cytochrome P450 26A10101
Voltage-dependent calcium channel gamma-2 subunit5005
HLA class I histocompatibility antigen, B alpha chain 3003
Cytochrome P450 1A20404
Cytochrome P450 3A40415
Retinoic acid receptor alpha0123
Retinoic acid receptor beta0123
Retinoic acid receptor gamma 0123
Glutamate receptor 26006
Retinoic acid receptor RXR-alpha0225
Retinoic acid receptor RXR-alpha0011
Retinoic acid receptor RXR-beta0112
Retinoic acid receptor RXR-beta0022
Retinoic acid receptor RXR-gamma0022
Type-1 angiotensin II receptor0112
Nuclear receptor subfamily 4 group A member 20011
Retinoic acid receptor RXR-gamma0112
Type-2 angiotensin II receptor0112
Oxysterols receptor LXR-beta0011
Spike glycoprotein3003
Retinoic acid receptor RXR-alpha0011
Oxysterols receptor LXR-alpha0011
Sigma non-opioid intracellular receptor 10202
Inositol hexakisphosphate kinase 13003
Canalicular multispecific organic anion transporter 10909
ATPase family AAA domain-containing protein 53003
Ataxin-24004
Cytochrome P450 26B10101
cytochrome P450 2C9, partial3003
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Chain A, Ferritin light chain4004
endonuclease IV2002
Nrf22002
glp-1 receptor, partial3003
15-lipoxygenase, partial3003
phosphopantetheinyl transferase6006
ATAD5 protein, partial7007
GLS protein3003
nonstructural protein 12002
67.9K protein5005
Parkin2002
IDH15005
peripheral myelin protein 22 isoform 12002
polyunsaturated fatty acid lipoxygenase ALOX122002
D(1A) dopamine receptor3003
chromobox protein homolog 15005
importin subunit beta-1 isoform 13003
serine/threonine-protein kinase mTOR isoform 12002
snurportin-13003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 13003
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
M-phase phosphoprotein 84004
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Aldo-keto reductase family 1 member B100202
Epidermal growth factor receptor0303
Pancreatic triacylglycerol lipase0001
Transthyretin0022
Estrogen receptor0202
Receptor tyrosine-protein kinase erbB-20303
Amyloid-beta precursor protein1225
Tyrosine-protein kinase Lck0202
Tyrosine-protein kinase Fyn0505
Aldo-keto reductase family 1 member B10606
Polyunsaturated fatty acid 5-lipoxygenase0202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B10202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Sodium-dependent noradrenaline transporter 0606
Mitogen-activated protein kinase 10101
Prostaglandin G/H synthase 20101
Alpha-synuclein1102
Histamine H2 receptor3003
D(1A) dopamine receptor1001
Aldo-keto reductase family 1 member C10101
TAR DNA-binding protein 434105
Integrase 0303
ATP-dependent phosphofructokinase7007
cytochrome P450 2D63003
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
DNA polymerase kappa isoform 13003
Thrombopoietin2002
cellular tumor antigen p53 isoform a4004
cytochrome P450 2C9 precursor1001
muscarinic acetylcholine receptor M14004
lethal factor (plasmid)1001
5-hydroxytryptamine receptor 40404
Integrin beta-34105
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40404
Integrin alpha-IIb4004
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Cytochrome P450 2D60404
Muscarinic acetylcholine receptor M10303
Angiotensin-converting enzyme0404
D(2) dopamine receptor0202
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Muscarinic acetylcholine receptor M30202
D(1A) dopamine receptor0202
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0404
Cytochrome P450 2C190202
Histamine H1 receptor0202
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60202
Sodium-dependent dopamine transporter 0202
Sigma intracellular receptor 20101
Nuclear receptor subfamily 3 group C member 3 0404
Sigma non-opioid intracellular receptor 10303
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0202
Protein cereblon0202
Chain A, Cruzipain1001
prostaglandin E2 receptor EP2 subtype1001
mitogen-activated protein kinase 14004
Solute carrier family 22 member 20203
Solute carrier organic anion transporter family member 1A50001
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 60002
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 200202
Solute carrier family 22 member 80002
Solute carrier family 22 member 60202
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110002
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Bile salt export pump0303
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Acetylcholinesterase0101
ATP-dependent translocase ABCB10406
5-hydroxytryptamine receptor 1A0101
Amine oxidase [flavin-containing] B0202
Amine oxidase [flavin-containing] A 0202
Amine oxidase [flavin-containing] A 0101
Acetylcholinesterase0101
Liver carboxylesterase 10101
Acetylcholinesterase 0303
Amine oxidase [flavin-containing] B0606
Sodium-dependent serotonin transporter0101
Acetylcholinesterase0101
Glycogen synthase kinase-3 beta0213
Beta-secretase 10101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Cholinesterase0101
Acetylcholine receptor subunit epsilon0112
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Acyl-CoA:cholesterol acyltransferase 0101
Carboxylic ester hydrolase 0101
Carboxylic ester hydrolase 0303
Histamine H3 receptor0202
Glycogen phosphorylase, muscle form0101
Asialoglycoprotein receptor 10112
NPYLR7B0011
Adenosine receptor A30101
Cytochrome P450 2C9 0101
Adenosine receptor A10102
Adenosine receptor A2b0101
Adenosine receptor A10101
Adenosine receptor A2a0203
chaperonin-containing TCP-1 beta subunit homolog1001
flap endonuclease 14004
Synaptic vesicle glycoprotein 2A0101
potassium voltage-gated channel subfamily H member 2 isoform d1001
inositol monophosphatase 11001
Cholecystokinin receptor type A1001
Gastrin/cholecystokinin type B receptor1001
interleukin 82002
ClpP2002
aryl hydrocarbon receptor4004
ras-related protein Rab-9A4004
Cytochrome P450 1A10101
Cytochrome P450 1A2 0101
Myeloperoxidase0101
Cytochrome P450 2C11 0101
Aromatase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Metabotropic glutamate receptor 10101
Mu-type opioid receptor0303
Nociceptin receptor0101
Alpha-1A adrenergic receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear receptor ROR-gamma2002
Nuclear factor erythroid 2-related factor 20001
Palmitoleoyl-protein carboxylesterase NOTUM0101
Dihydrofolate reductase0304
Dipeptidyl peptidase 40101
Multidrug and toxin extrusion protein 10202
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
dopamine D1 receptor2002
Thymidylate synthase 0101
Thymidylate synthase 0101
nuclear factor erythroid 2-related factor 2 isoform 24004
transcriptional regulator ERG isoform 31001
DNA polymerase beta2002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
DNA polymerase iota isoform a (long)4004
transactivating tegument protein VP16 [Human herpesvirus 1]0101
muscleblind-like protein 1 isoform 12002
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10112
Carbonic anhydrase 20214
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0102
Delta-type opioid receptor0202
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30405
Protein-arginine deiminase type-40101
Broad substrate specificity ATP-binding cassette transporter ABCG20103
Chain A, Probable serine/threonine-protein kinase pknB0101
WRN1001
NFKB1 protein, partial1001
Smad33003
apical membrane antigen 1, AMA11001
DNA polymerase III, partial1001
hypothetical protein, conserved1001
nonstructural protein 10101
LANA0001
pyruvate kinase1001
phospholipase A2, group III0101
NPC intracellular cholesterol transporter 1 precursor4004
interferon gamma precursor0001
atrial natriuretic peptide receptor 1 precursor1001
histone-lysine N-methyltransferase NSD2 isoform 10001
atrial natriuretic peptide receptor 2 precursor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
protein AF-9 isoform a0001
tyrosine-protein kinase Yes2002
GTP-binding nuclear protein Ran isoform 11001
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
rac GTPase-activating protein 1 isoform a0101
Vpr1001
DNA repair protein RAD52 homolog isoform a0001
pyruvate kinase PKM isoform b1001
Solute carrier family 22 member 30101
Glycoprotein hormones alpha chain1001
Proto-oncogene tyrosine-protein kinase ROS0101
Ornithine decarboxylase1001
DNA topoisomerase 2-alpha0102
Polyunsaturated fatty acid lipoxygenase ALOX150101
DNA topoisomerase 20001
Casein kinase II subunit alpha'0101
Guanine nucleotide-binding protein G1001
Casein kinase II subunit beta0101
Casein kinase II subunit alpha0101
DNA topoisomerase 2-beta0001
Tyrosine-protein kinase BTK0101
NEDD8-activating enzyme E1 regulatory subunit0011
Multidrug and toxin extrusion protein 20101
Casein kinase II subunit alpha 30101
NEDD8-activating enzyme E1 catalytic subunit0011
Single-stranded DNA cytosine deaminase1001
P2Y purinoceptor 120101
phosphoglycerate kinase1001
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
5-hydroxytryptamine receptor 3E0101
Neuronal acetylcholine receptor subunit alpha-40213
Transient receptor potential cation channel subfamily A member 10011
5-hydroxytryptamine receptor 3B0101
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-30225
Acetylcholine receptor subunit gamma0213
Muscarinic acetylcholine receptor M10112
Muscarinic acetylcholine receptor M30112
Muscarinic acetylcholine receptor M40213
Muscarinic acetylcholine receptor M50112
Neuronal acetylcholine receptor subunit alpha-40101
Neuronal acetylcholine receptor subunit alpha-40225
Muscarinic acetylcholine receptor M20112
Acetylcholine receptor subunit beta0213
Cytochrome P450 2A60213
Neuronal acetylcholine receptor subunit alpha-20225
Neuronal acetylcholine receptor subunit beta-20225
Neuronal acetylcholine receptor subunit beta-30225
Neuronal acetylcholine receptor subunit beta-40225
Translocator protein0101
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-50225
Cytochrome P450 2A50101
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit beta-40213
Muscarinic acetylcholine receptor M40101
Neuronal acetylcholine receptor subunit alpha-30213
Delta-type opioid receptor0101
Neuronal acetylcholine receptor subunit alpha-70224
Neuronal acetylcholine receptor subunit alpha-60225
Neuronal acetylcholine receptor subunit alpha-90225
Neuronal acetylcholine receptor subunit alpha-40213
5-hydroxytryptamine receptor 3A0101
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Mu-type opioid receptor0101
Neuronal acetylcholine receptor subunit beta-30112
Neuronal acetylcholine receptor subunit alpha-70225
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
5-hydroxytryptamine receptor 3D0101
Transient receptor potential cation channel subfamily A member 10011
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
5-hydroxytryptamine receptor 3C0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-100225
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
Transporter0113
Chain A, Beta-lactamase4004
Genome polyprotein 0101
pregnane X receptor2002
Tubulin alpha-1A chain0012
Tubulin beta chain0011
Tubulin beta-4A chain0113
Integrin alpha-V 0101
Tubulin beta chain0113
60 kDa chaperonin0101
Tubulin alpha-3C chain0113
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
60 kDa heat shock protein, mitochondrial0101
Fibroblast growth factor receptor 10101
Proto-oncogene tyrosine-protein kinase Src0202
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
ATP-dependent translocase ABCB10101
Substance-K receptor0202
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 1A40101
Serum paraoxonase/arylesterase 10101
Cholecystokinin receptor type A0202
Melanocortin receptor 50202
UDP-glucuronosyltransferase 2B10 0101
Delta-type opioid receptor0202
10 kDa heat shock protein, mitochondrial0101
Tubulin alpha-1B chain0113
Tubulin alpha-4A chain0113
Tubulin beta-4B chain0113
Bcl-2-like protein 10101
Tyrosine-protein kinase Mer0101
Tubulin beta-3 chain0214
Tubulin beta-2A chain0113
Thiosulfate sulfurtransferase0101
Beta-tubulin 0101
Tubulin beta-8 chain0113
60 kDa chaperonin 0101
Tubulin beta-2B chain0013
Tubulin alpha-3E chain0113
Tubulin alpha-1A chain0113
10 kDa chaperonin 0101
Similar to alpha-tubulin isoform 1 0013
Similar to alpha-tubulin isoform 1 0002
Tubulin alpha-1C chain0113
Tubulin beta-6 chain0113
Tubulin beta-2B chain0113
Tubulin beta-1 chain0113
Nucleotide-binding oligomerization domain-containing protein 20101
Solute carrier organic anion transporter family member 1B10202
CDGSH iron-sulfur domain-containing protein 10101
Free fatty acid receptor 10011
Peroxisome proliferator-activated receptor gamma0101
Steryl-sulfatase0101
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Peroxisome proliferator-activated receptor alpha0101
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Peroxisome proliferator-activated receptor gamma0225
Peroxisome proliferator-activated receptor gamma0112
Carnitine O-palmitoyltransferase 1, liver isoform0101
Peroxisome proliferator-activated receptor alpha0112
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
CDGSH iron-sulfur domain-containing protein 20101
CDGSH iron-sulfur domain-containing protein 10202
BRCA11001
thioredoxin glutathione reductase2002
histone deacetylase 9 isoform 32002
Carbonic anhydrase 10102
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit beta-20011
Dihydroorotate dehydrogenase (quinone), mitochondrial0202
Amine oxidase [flavin-containing] A0101
Amine oxidase [flavin-containing] B0101
Transient receptor potential cation channel subfamily V member 10012
PAX80001
Microphthalmia-associated transcription factor0001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Signal transducer and activator of transcription 30101
Thioredoxin reductase 1, cytoplasmic0101
Mcl-10101
bromodomain adjacent to zinc finger domain 2B1001
Replicase polyprotein 1ab0101
thyroid hormone receptor beta isoform a1001
pyruvate kinase PKM isoform a1001
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase0101
Polyphenol oxidase 20102
Interstitial collagenase0101
Transcription factor AP-10101
Replicase polyprotein 1ab0101
Glutamate receptor 11001
Glutamate receptor 31001
Glutamate receptor 41001
17-beta-hydroxysteroid dehydrogenase type 20101
Linoleate 9S-lipoxygenase-40101
UDP-galactopyranose mutase0011
Hyaluronidase-10101
UDP-galactopyranose mutase0011
Reverse transcriptase/RNaseH 0101
Tyrosinase0101
NAD(P)H dehydrogenase [quinone] 10001
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Carbonic anhydrase 120001
Carbonic anhydrase 30001
Carbonic anhydrase 40001
Carbonic anhydrase 60001
Carbonic anhydrase 5A, mitochondrial0001
Glutamate receptor ionotropic, NMDA 1 0001
Carbonic anhydrase0001
Carbonic anhydrase 70001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Carbonic anhydrase 90001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2D0001
Carbonic anhydrase 0001
Tubulin--tyrosine ligase0101
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Carbonic anhydrase 150001
Taste receptor type 2 member 140001
Glutamate receptor ionotropic, NMDA 3A0001
Carbonic anhydrase 140001
Carbonic anhydrase 5B, mitochondrial0001
Thromboxane A2 receptor 0001
Type-1A angiotensin II receptor 0112
Type-1B angiotensin II receptor0101
Type-1 angiotensin II receptor0214
Squalene synthase0101
Platelet glycoprotein VI0011
Leukotriene B4 receptor 20011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]