cilastatin--imipenem-drug-combination and Tongue--Hairy

Black tongue syndrome (BT) is a rare and self-limiting disorder which can result from physiological and metabolic condition and ingestion of toxic substances. Medications are the most common cause of BT.. A 39-year-old male patient presented with BT after the initiation of imipenem/cilastatin. Within one week of cessation of these drugs, the patient's tongue returned to a normal colour.. This is the first case of BT induced by imipenem/cilastatin. Withdrawal of the combination is likely to reverse the condition.

Topics: Adult; Anti-Bacterial Agents; Cilastatin, Imipenem Drug Combination; Humans; Male; Tongue, Hairy