Page last updated: 2024-09-27

Systemic Vasculitis

A heterogeneous group of diseases characterized by inflammation and necrosis of the blood vessel walls.

Synonyms(1)

Synonym
Systemic Vasculitis

Research Excerpts

Overview

ExcerptReference
"Systemic vasculitis is a multisystem disease characterized by inflammation of blood vessels."( Bertagna, F; Biasiotto, G; Bosio, G; Caobelli, F; Giubbini, R; Motta, F, 2010)
"Systemic vasculitis is a heterogeneous group of diseases characterized by infiltrates consisting of neutrophils infiltrated the walls of blood vessels of various caliber."( Agnieszka, H; Konieczny, A; Ryba, M; Sroka, M; Zbigniew, H, 2013)
"Primary systemic vasculitis is a group of heterogeneous disorders, characterized by inflammation of blood vessels causing end organ damage from ischemia, aneurysm formation or dissection."( Danve, A; O'Dell, J, 2015)
"Systemic vasculitis is a rare vemurafenib-associated adverse event that may be life-threatening."( Barete, S; Cacoub, P; Comarmond, C; Domont, F; Mirouse, A; Plaisier, E; Rouvier, P; Saadoun, D; Savey, L, 2016)

Context

ExcerptReference
"Four cases of systemic vasculitis have been reported in our series, and they have a worse prognosis."( Belizna, C; Beucher, A; de Hollanda, A; Ghali, A; Hamidou, M; Henrion, D; Ifrah, N; Lavigne, C; Lévesque, H; Subra, JF, 2011)

Research

Studies (90)

TimeframeStudies, This Condition (%)All Conditions %
pre-19904 (4.44)23.3326
1990's0 (0.00)12.5806
2000's1 (1.11)18.1394
2010's72 (80.00)28.8240
2020's13 (14.44)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carbon monoxide0medium11
n(g),n(g')-dimethyl-l-arginine0low10
nitrites0medium11
sulfur dioxide0medium11
azathioprine0medium51
carvedilol0low10
ethosuximide0low10
hydroxychloroquine0low30
sotalol0low10
tetraethylammonium0low10
prednisolone0low50
prednisone0low60
arginine0low20
methylprednisolone0low30
pyrazines0low10
vidarabine0low10
ozone0medium11
trolamine salicylate0low60
levamisole0low30
triamcinolone0low10
ribavirin0low10
fluorodeoxyglucose f180medium91
fibrinogen0low10
homocysteine0low10
n,n-dimethylarginine0low10
methotrexate0medium41
angiotensin ii0low10
bortezomib0low10
retinol0medium11
cocaine0low30
mycophenolic acid0medium51
fludarabine0low10
calcitriol0low10
phenylephrine hydrochloride0low10
mocetinostat0low70
rivaroxaban0low10
cardiovascular agents0low50
plx40320low10
minocycline0low20
calca protein, human0low10
transforming growth factor beta0low10
lewis x antigen0low10
exudates0low10
eye0low10
leptin0low10

Protein Targets (888)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Ferritin light chain4004
Thymidine kinase 0101
thioredoxin reductase120012
phosphopantetheinyl transferase6006
GLS protein5005
TDP1 protein130013
Smad33003
thyroid stimulating hormone receptor6006
EWS/FLI fusion protein130013
arylsulfatase A8008
euchromatic histone-lysine N-methyltransferase 2130013
activating transcription factor 63003
Histone H2A.x6006
Bloom syndrome protein isoform 15005
hemoglobin subunit beta2002
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
lamin isoform A-delta10100010
Solute carrier family 22 member 1 0307
ATP-binding cassette sub-family C member 3012012
Multidrug resistance-associated protein 4012013
Solute carrier family 22 member 60001
Bile salt export pump0303
Bile salt export pump013013
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0002
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0506
Cytochrome P450 2J20404
Disintegrin and metalloproteinase domain-containing protein 172002
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60002
Thymidine kinase 0101
Solute carrier family 22 member 80002
Canalicular multispecific organic anion transporter 1012012
Thymidine kinase0101
glucocerebrosidase1001
DNA polymerase kappa isoform 12002
histone acetyltransferase KAT2A isoform 12002
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0213
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0224
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0202
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
NFKB1 protein, partial4004
alpha-galactosidase3003
cytochrome P450 2C19 precursor2002
chromobox protein homolog 17007
flap endonuclease 14004
DNA polymerase iota isoform a (long)4004
muscarinic acetylcholine receptor M14004
lethal factor (plasmid)2002
Cytochrome P450 3A40305
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0102
Nitric oxide synthase, brain 0102
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase7007
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
interleukin 83003
acetylcholinesterase5005
RAR-related orphan receptor gamma9009
SMAD family member 24004
ATAD5 protein, partial4004
Fumarate hydratase3003
SMAD family member 34004
GLI family zinc finger 37007
Microtubule-associated protein tau5005
AR protein140014
thioredoxin glutathione reductase4004
nuclear receptor subfamily 1, group I, member 38008
glucocorticoid receptor [Homo sapiens]9009
retinoic acid nuclear receptor alpha variant 16006
retinoid X nuclear receptor alpha7007
estrogen-related nuclear receptor alpha140014
farnesoid X nuclear receptor5005
pregnane X nuclear receptor8008
estrogen nuclear receptor alpha120012
G3003
polyprotein3003
P531001
peroxisome proliferator-activated receptor delta5005
peroxisome proliferator activated receptor gamma7007
IDH15005
aryl hydrocarbon receptor3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
thyroid stimulating hormone receptor3003
v-jun sarcoma virus 17 oncogene homolog (avian)3003
peripheral myelin protein 22 isoform 13003
cellular tumor antigen p53 isoform a2002
thyroid hormone receptor beta isoform 28008
heat shock protein beta-14004
nuclear factor erythroid 2-related factor 2 isoform 1100010
geminin120012
peripheral myelin protein 226006
survival motor neuron protein isoform d4004
cytochrome P450 3A4 isoform 15005
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 14004
Gamma-aminobutyric acid receptor subunit pi5005
Voltage-dependent calcium channel gamma-2 subunit6006
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 3003
Cellular tumor antigen p53100010
Gamma-aminobutyric acid receptor subunit beta-15005
Gamma-aminobutyric acid receptor subunit delta5005
Gamma-aminobutyric acid receptor subunit gamma-25005
Glutamate receptor 26107
Gamma-aminobutyric acid receptor subunit alpha-55005
Gamma-aminobutyric acid receptor subunit alpha-35005
Gamma-aminobutyric acid receptor subunit gamma-15005
Gamma-aminobutyric acid receptor subunit alpha-25005
Gamma-aminobutyric acid receptor subunit alpha-45005
Gamma-aminobutyric acid receptor subunit gamma-35005
Gamma-aminobutyric acid receptor subunit alpha-65005
Nuclear receptor ROR-gamma4004
Gamma-aminobutyric acid receptor subunit alpha-15005
Gamma-aminobutyric acid receptor subunit beta-35005
Gamma-aminobutyric acid receptor subunit beta-25005
GABA theta subunit5005
Inositol hexakisphosphate kinase 13003
ATPase family AAA domain-containing protein 57007
Ataxin-29009
Gamma-aminobutyric acid receptor subunit epsilon5005
Protein-arginine deiminase type-40404
cytochrome P450 2C9, partial3003
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110101
PPM1D protein4004
caspase 7, apoptosis-related cysteine protease1001
estrogen receptor 2 (ER beta)6006
progesterone receptor7007
cytochrome P450 family 3 subfamily A polypeptide 45005
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
caspase-31001
nuclear receptor subfamily 1, group I, member 23003
Caspase-71001
caspase-31001
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70101
Histone deacetylase 30303
26S proteasome non-ATPase regulatory subunit 30101
Carbonic anhydrase 120101
Prothrombin0202
Chymotrypsinogen A0101
Carbonic anhydrase 10303
Carbonic anhydrase 20314
Carbonic anhydrase 30101
Cathepsin B0101
Neutrophil elastase0101
Cathepsin G0202
Lysosomal protective protein0101
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0101
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10102
Carbonic anhydrase 40202
Carbonic anhydrase 60202
Chymase0101
Proteasome subunit alpha type-10101
Proteasome subunit alpha type-20101
Proteasome subunit alpha type-30101
Proteasome subunit alpha type-40101
Proteasome subunit beta type-80101
Proteasome subunit beta type-80101
Proteasome subunit beta type-90101
Proteasome subunit alpha type-50101
Proteasome subunit beta type-40101
Proteasome subunit beta type-60101
Proteasome subunit beta type-50203
Carbonic anhydrase 5A, mitochondrial0101
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100101
Carbonic anhydrase 70101
26S proteasome regulatory subunit 6B0112
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30101
Proteasome subunit beta type-20102
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60101
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20101
Histone deacetylase 10303
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
Carbonic anhydrase 90101
ATP-dependent Clp protease proteolytic subunit0112
Carbonic anhydrase 130101
NACHT, LRR and PYD domains-containing protein 3 0101
Proteasome subunit alpha-type 80101
Histone deacetylase 20303
Proteasome subunit beta type-70101
26S proteasome non-ATPase regulatory subunit 10101
Carbonic anhydrase 150202
Histone deacetylase 80202
Histone deacetylase 60202
Carbonic anhydrase 140101
26S proteasome non-ATPase regulatory subunit 130101
Carbonic anhydrase 5B, mitochondrial0101
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Beta-lactamase2002
Vitamin D3 receptor0011
USP1 protein, partial3003
mitogen-activated protein kinase 13003
nuclear receptor ROR-gamma isoform 15005
Vitamin D-binding protein0011
Cytochrome P450 1A20001
Androgen receptor0303
Cytochrome P450 2D60202
Vitamin D3 receptor0124
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0011
Cytochrome P450 2C190202
Kappa-type opioid receptor0011
Vitamin D3 receptor0011
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
Chain A, 2-oxoglutarate Oxygenase4004
bromodomain adjacent to zinc finger domain 2B2002
lysosomal alpha-glucosidase preproprotein2002
D(1A) dopamine receptor1001
serine/threonine-protein kinase mTOR isoform 11001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
short transient receptor potential channel 6 isoform 10011
Toll-like receptor 40202
Solute carrier family 22 member 20203
5-hydroxytryptamine receptor 40202
Potassium channel subfamily K member 20101
Amyloid-beta precursor protein0303
Beta-2 adrenergic receptor0426
Aldo-keto reductase family 1 member B10202
ATP-dependent translocase ABCB10101
Beta-1 adrenergic receptor0426
Alpha-2A adrenergic receptor0303
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
Angiotensin-converting enzyme0202
Beta-3 adrenergic receptor0325
D(2) dopamine receptor0202
Alpha-2B adrenergic receptor0303
Alpha-2C adrenergic receptor0303
5-hydroxytryptamine receptor 1A0303
D(1A) dopamine receptor0202
UDP-glucuronosyltransferase 1A1 0102
Sodium-dependent noradrenaline transporter 0404
Alpha-1D adrenergic receptor0404
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0303
Sodium-dependent serotonin transporter0404
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 2B0202
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
Potassium channel subfamily K member 100101
Sodium-dependent dopamine transporter 0404
Potassium voltage-gated channel subfamily H member 20505
Cytochrome P450 1B10101
Nuclear receptor subfamily 3 group C member 3 0202
Multidrug and toxin extrusion protein 10101
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10101
5-hydroxytryptamine receptor 2C0304
Tryptophan 5-hydroxylase 10101
5-hydroxytryptamine receptor 2A0303
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
D0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Liver carboxylesterase 10001
Sodium-dependent dopamine transporter0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50101
Sodium-dependent serotonin transporter0304
5-hydroxytryptamine receptor 7 0101
Gamma-aminobutyric acid receptor subunit alpha-30101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Glutamate receptor ionotropic, NMDA 1 0101
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0101
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Glutamate receptor ionotropic, NMDA 3B0101
Sigma non-opioid intracellular receptor 10303
Gamma-aminobutyric acid receptor subunit gamma-30101
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A0101
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0202
hypoxia-inducible factor 1 alpha subunit3003
neuropeptide S receptor isoform A1001
Voltage-dependent T-type calcium channel subunit alpha-1I0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
corticotropin-releasing hormone receptor 20112
67.9K protein4004
corticotropin releasing factor-binding protein0112
nuclear factor erythroid 2-related factor 2 isoform 28008
glycogen synthase kinase-3 beta isoform 10033
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
5'-nucleotidase0101
Adenosine receptor A30101
Adenosine deaminase 0002
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10203
Genome polyprotein 0101
Spike glycoprotein0022
Replicase polyprotein 1ab0022
Transmembrane protease serine 20022
Procathepsin L0022
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Spike glycoprotein3025
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Angiotensin-converting enzyme 2 0022
Toll-like receptor 90101
Toll-like receptor 70101
dopamine D1 receptor2002
cytochrome P450 2D62002
Alkaline phosphatase, tissue-nonspecific isozyme0202
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Phospholipase A-2-activating protein0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
15-lipoxygenase, partial2002
aldehyde dehydrogenase 1 family, member A15005
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
vitamin D3 receptor isoform VDRA3003
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10022
Thymidylate synthase0202
Integrin beta-31001
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
Integrin alpha-IIb1001
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20022
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
TAR DNA-binding protein 432002
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Broad substrate specificity ATP-binding cassette transporter ABCG20001
nonstructural protein 11001
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor08215
Glycine receptor subunit alpha-10808
Androgen receptor0303
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Nuclear receptor subfamily 1 group I member 20011
Albumin0112
Stromelysin-10101
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Histone deacetylase 40101
Histone deacetylase 70101
Histone deacetylase 11 0101
Histone deacetylase 50101
Nuclear receptor corepressor 20101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
glp-1 receptor, partial3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
UDP-glucuronosyltransferase 1A90001
Inosine-5'-monophosphate dehydrogenase 20213
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
Peroxisome proliferator-activated receptor gamma0011
Alpha-synuclein1102
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
Carbonic anhydrase0101
GALC protein1001
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Chain A, AKAP9-BRAF fusion protein0101
tyrosine-protein kinase Yes1001
Bone morphogenetic protein receptor type-1B0011
Membrane-associated progesterone receptor component 10011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pirin0101
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Epidermal growth factor receptor0112
GTPase KRas0101
RAF proto-oncogene serine/threonine-protein kinase0113
High affinity nerve growth factor receptor0011
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0011
Tyrosine-protein kinase Fyn0011
Cyclin-dependent kinase 10011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0112
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Proto-oncogene tyrosine-protein kinase Src0011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0124
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Deoxycytidine kinase0011
Serine/threonine-protein kinase B-raf 0101
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
DNA replication licensing factor MCM40011
Myosin-100011
Vascular endothelial growth factor receptor 20101
Dual specificity mitogen-activated protein kinase kinase 20112
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 40011
Dual specificity mitogen-activated protein kinase kinase 30011
Dual specificity mitogen-activated protein kinase kinase 40011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
Heat shock factor protein 10101
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10112
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Aspartyl/asparaginyl beta-hydroxylase0101
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Serine/threonine-protein kinase ATR0011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Cyclin-dependent kinase 100011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Putative heat shock protein HSP 90-beta 20011
Rab-like protein 30011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Serine/threonine-protein kinase Nek10011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Phenylalanine--tRNA ligase beta subunit0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200112
Cyclin-dependent kinase 120011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Long-chain-fatty-acid--CoA ligase 50011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase 38-like0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Histamine H1 receptor0022
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
pregnane X receptor2002
Translocator protein0101
Integrase 0101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Chain A, Cruzipain1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
potassium voltage-gated channel subfamily H member 2 isoform d2002
Retinol-binding protein 40011
Beta-lactoglobulin0011
NS5 0011
Thrombopoietin1001
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Rap guanine nucleotide exchange factor 31001
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Adenosine receptor A30101
Adenosylhomocysteinase0002
Adenosine receptor A2a0101
Adenosine receptor A10101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Adenosine receptor A10101
Genome polyprotein0011
Chain A, Activated Factor Xa Heavy Chain0101
Coagulation factor X0202
Coagulation factor XII0101
Suppressor of tumorigenicity 14 protein0101
regulator of G-protein signaling 41001
POU domain, class 2, transcription factor 10001
Beta-2 adrenergic receptor0101
Beta-2 adrenergic receptor 0011
Solute carrier family 22 member 10203
Solute carrier family 22 member 20102
Solute carrier family 22 member 50001
Solute carrier family 22 member 30202
Solute carrier family 22 member 30001
5-hydroxytryptamine receptor 70001
Potassium voltage-gated channel subfamily A member 10101
Solute carrier family 22 member 10203
Solute carrier family 22 member 40001
Solute carrier family 22 member 20203
Solute carrier family 22 member 40101
Solute carrier family 22 member 30001
Solute carrier family 22 member 50001
Solute carrier family 22 member 40001
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
procathepsin L isoform 1 preproprotein0101
Dipeptidyl peptidase 40101
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]