Page last updated: 2024-09-03

nitisinone and Ochronosis

nitisinone has been researched along with Ochronosis in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's7 (63.64)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Havranova, A; Imrich, R; Lukacova, O; Penesova, A; Radikova, Z; Ranganath, L; Sedlakova, J; Vlcek, M; Zanova, E; Zatkova, A1
Davidson, J; Gallagher, JA; Ranganath, LR; Vinjamuri, S1
Gallagher, JA; Khedr, M; Ranganath, LR; Vinjamuri, S1
Barton, GJ; Briggs, M; Cox, TF; Daroszewska, A; Davison, AS; Devine, JM; Dillon, JP; Fisher, M; Gallagher, JA; Griffin, R; Harrold, J; Hughes, AT; Hughes, G; Jarvis, JC; Jones, A; Judd, S; Khedr, M; Loftus, N; McCormick, M; Milan, AM; Psarelli, EE; Ranganath, LR; Sireau, N; Taylor, S; Usher, JL; Vinjamuri, S; West, E1
Gallagher, JA; Jarvis, JC; Keenan, CM; Preston, AJ; Ranganath, LR; Sutherland, H; Taylor, AM; Williams, DP; Wilson, PJ; Wlodarski, B1
Arnoux, JB; Brassier, A; de Lonlay, P; Dubois, S; Grisel, C; Job-Deslandre, C; Le Quan Sang, KH; Ranganath, L; Servais, A; Sireau, N; Wippf, J1
Gallagher, JA; Ranganath, LR; Timmis, OG1
Anolik, R; Pomeranz, MK; Yancovitz, M1
Cox, TF; Ranganath, L1
Cox, TF; Ranganath, LR1
Jaffe, IA; Keller, JM; Macaulay, W; Nercessian, OA1

Reviews

2 review(s) available for nitisinone and Ochronosis

ArticleYear
Old treatments for new insights and strategies: proposed management in adults and children with alkaptonuria.
    Journal of inherited metabolic disease, 2015, Volume: 38, Issue:5

    Topics: Adult; Age Factors; Alkaptonuria; Antioxidants; Child; Cyclohexanones; Humans; Nitrobenzoates; Ochronosis; Phenylalanine; Tyrosine

2015
New developments in ochronosis: review of the literature.
    Rheumatology international, 2005, Volume: 25, Issue:2

    Topics: Alkaptonuria; Arthroplasty, Replacement; Cyclohexanones; Enzyme Inhibitors; Humans; Joint Diseases; Nitrobenzoates; Ochronosis

2005

Other Studies

9 other study(ies) available for nitisinone and Ochronosis

ArticleYear
Nutritional interventions for patients with alkaptonuria: A minireview.
    Endocrine regulations, 2023, Jan-01, Volume: 57, Issue:1

    Topics: Alkaptonuria; Homogentisic Acid; Humans; Ochronosis; Tyrosine; Tyrosinemias

2023
Characterising the arthroplasty in spondyloarthropathy in a large cohort of eighty-seven patients with alkaptonuria.
    Journal of inherited metabolic disease, 2021, Volume: 44, Issue:3

    Topics: Aged; Alkaptonuria; Arthroplasty; Cohort Studies; Cyclohexanones; Female; Humans; Linear Models; Male; Middle Aged; Nitrobenzoates; Ochronosis; Positron Emission Tomography Computed Tomography; Spondylarthropathies; United Kingdom

2021
Characterizing the alkaptonuria joint and spine phenotype and assessing the effect of homogentisic acid lowering therapy in a large cohort of 87 patients.
    Journal of inherited metabolic disease, 2021, Volume: 44, Issue:3

    Topics: Aged; Alkaptonuria; Cohort Studies; Cyclohexanones; Female; Homogentisic Acid; Humans; Joints; Linear Models; Male; Middle Aged; Nitrobenzoates; Ochronosis; Phenotype; Positron Emission Tomography Computed Tomography; Severity of Illness Index; Spine; United Kingdom

2021
Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre.
    Molecular genetics and metabolism, 2018, Volume: 125, Issue:1-2

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Cyclohexanones; Disease Progression; Female; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Ochronosis; United Kingdom

2018
Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone.
    Annals of the rheumatic diseases, 2014, Volume: 73, Issue:1

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Animals; Chondrocytes; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Joint Diseases; Knee Joint; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitrobenzoates; Ochronosis

2014
Progress in Alkaptonuria--are we near to an effective therapy?
    Journal of inherited metabolic disease, 2015, Volume: 38, Issue:5

    Topics: Alkaptonuria; Animals; Cyclohexanones; Disease Models, Animal; Genetic Therapy; Humans; Mice; Nitrobenzoates; Ochronosis; Treatment Outcome

2015
Alkaptonuria.
    Dermatology online journal, 2010, Nov-15, Volume: 16, Issue:11

    Topics: Aged; Alkaptonuria; Arthritis; Cyclohexanones; Female; Homogentisic Acid; Humans; Joint Diseases; Nitrobenzoates; Ochronosis; Pigmentation Disorders

2010
A quantitative assessment of alkaptonuria: testing the reliability of two disease severity scoring systems.
    Journal of inherited metabolic disease, 2011, Volume: 34, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Alkaptonuria; Causality; Cohort Studies; Comorbidity; Cyclohexanones; Female; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Hypertension; Male; Middle Aged; Nitrobenzoates; Ochronosis; Pain; Regression Analysis; Reproducibility of Results; Severity of Illness Index; Sex Distribution; Smoking; Surveys and Questionnaires

2011
Natural history of alkaptonuria revisited: analyses based on scoring systems.
    Journal of inherited metabolic disease, 2011, Volume: 34, Issue:6

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Adult; Aged; Aged, 80 and over; Alkaptonuria; Arthralgia; Arthritis; Cartilage, Articular; Causality; Cohort Studies; Comorbidity; Cyclohexanones; Disease Progression; Female; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Ochronosis; Pain; Surveys and Questionnaires

2011