Page last updated: 2024-10-16

quinacrine and Ochronosis

quinacrine has been researched along with Ochronosis in 4 studies

Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Ochronosis: The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SUGAR, HS1
WADDELL, WW1
LUDWIG, GD1
TOOLE, JF1
WOOD, JC1
Egorin, MJ1
Trump, DL1
Wainwright, CW1
Tuffanelli, DL1

Other Studies

4 other studies available for quinacrine and Ochronosis

ArticleYear
Ochronosis-like pigmentation associated with the use of atabrine.
    The Illinois medical journal, 1946, Volume: 89

    Topics: Ochronosis; Pigmentation; Quinacrine

1946
OCHRONOSIS FROM QUINACRINE (ATABRINE).
    Annals of internal medicine, 1963, Volume: 59

    Topics: Arthritis; Femoral Nerve; Humans; Neuritis; Ochronosis; Paresthesia; Peripheral Nervous System Disea

1963
Quinacrine ochronosis and rheumatoid arthritis.
    JAMA, 1976, Jul-26, Volume: 236, Issue:4

    Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Ochronosis; Quinacrine

1976
Quinacrine ochronosis.
    JAMA, 1976, Nov-29, Volume: 236, Issue:22

    Topics: Humans; Ochronosis; Quinacrine; Terminology as Topic

1976