quinone has been researched along with Ochronosis in 1 studies
benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).
Ochronosis: The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Such a deficiency leads to the accumulation of homogentisic acid (HGA) and its oxidized/polymerized products in connective tissues, where melanin-like pigments accumulate (ochronosis)." | 7.77 | Redox-proteomics of the effects of homogentisic acid in an in vitro human serum model of alkaptonuric ochronosis. ( Bernardini, G; Bianchini, C; Braconi, D; Laschi, M; Millucci, L; Santucci, A; Spreafico, A, 2011) |
| " Such a deficiency leads to the accumulation of homogentisic acid (HGA) and its oxidized/polymerized products in connective tissues, where melanin-like pigments accumulate (ochronosis)." | 3.77 | Redox-proteomics of the effects of homogentisic acid in an in vitro human serum model of alkaptonuric ochronosis. ( Bernardini, G; Bianchini, C; Braconi, D; Laschi, M; Millucci, L; Santucci, A; Spreafico, A, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braconi, D | 1 |
| Bianchini, C | 1 |
| Bernardini, G | 1 |
| Laschi, M | 1 |
| Millucci, L | 1 |
| Spreafico, A | 1 |
| Santucci, A | 1 |
1 other study available for quinone and Ochronosis
| Article | Year |
|---|---|
Redox-proteomics of the effects of homogentisic acid in an in vitro human serum model of alkaptonuric ochronosis.
Topics: Alkaptonuria; Benzoquinones; Glutathione Peroxidase; Glutathione Reductase; Homogentisic Acid; Human | 2011 |