Page last updated: 2024-09-27

Myofibromatosis

A condition characterized by multiple formations of myofibromas (LEIOMYOMA).

Synonyms(1)

Synonym
Myofibromatosis

Research Excerpts

Overview

ExcerptReference
"Infantile myofibromatosis is a rare clinical entity characterized by multiple mesenchymal tumors in the neonatal period."( Hasegawa, M; Kida, S; Takakuwa, S; Yamashima, T; Yamashita, J, 1995)
"Infantile myofibromatosis is the most common fibrous tumor of infancy."( Gandhi, MM; Levitt, GA; Nathan, PC; Weitzman, S, 2003)
"Infantile myofibromatosis is a rare disorder of infancy that can provoke osteolytic lesions."( Burmamm, TG; Cruz, AA; Maia, EM; Perez, LC; Santos, AN; Tone, LG; Valera, ET, 2004)
"Infantile myofibromatosis is the most common fibrous tumor of infancy."( Hernandez, RJ; Koujok, K; Ruiz, RE, 2005)
"Infantile myofibromatosis is the most frequent fibromatosis in childhood."( Fraitag, S; Grossin, M; Hénin, D; Petit, T, 2004)
"Infantile myofibromatosis is a disorder of infancy and early childhood, typically presenting as a solitary lesion or multiple widespread nodular tumors localized to skin, subcutaneous tissue, muscle, bone, viscera, or central nervous system."( Huang, CJ; Jung, SM; Lin, KL; Wang, HS; Wu, CT, 2005)
"Infantile myofibromatosis is a rare proliferative mesenchymal disorder that has a potential for rapid growth and recurrence."( Ardeshirpour, F; Drake, AF; Ebert, CS; Hart, CF; Patel, M; Zdanski, C, 2008)
"Infantile myofibromatosis is a rare myofibroblastic proliferative disorder characterized by firm, skin-colored to red-purple cutaneous and subcutaneous nodules; these are the most prevalent fibrous tumors observed in infancy."( Bodmer, J; Diaz-Miron, JL; Kim, LS; Maymone, MB; Szeto, MD; Treece, AL, 2021)
"Infantile myofibromatosis is a rare benign congenital tumour that often regresses spontaneously but may pose therapeutic challenges in its widespread visceral form."( Clauditz, T; Königs, I; Kordes, U; Reinshagen, K; Schubert, JP; Wößmann, W, 2023)

Context

ExcerptReference
"Myofibroma and myofibromatosis have been described under different names since 1951."( Difabio, VE; Nikitakis, NG; Sauk, JJ; Scheper, MA, 2005)

Research

Studies (43)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (2.33)23.3326
1990's4 (9.30)12.5806
2000's13 (30.23)18.1394
2010's12 (27.91)28.8240
2020's13 (30.23)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low60
dimethyl sulfoxide0low10
pentetic acid0low10
indomethacin0low10
prednisolone0low10
prednisone0low10
pyrroles0low10
reticulin0low10
cladribine0low10
gadolinium0low20
propiconazole0low10
fluorodeoxyglucose f180low10
imatinib mesylate0low90
methotrexate0low80
erlotinib hydrochloride0low10
sorafenib0low10
inositol 3-phosphate0low10
dactinomycin0low30
bromochloroacetic acid0low10
u 01260low10
dasatinib0low10
sirolimus0low10
su 112480low20
gadolinium dtpa0low10
fr 1802040low10
technetium tc 99m medronate0low10

Protein Targets (953)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma7007
AR protein110011
aldehyde dehydrogenase 1 family, member A16006
nuclear receptor subfamily 1, group I, member 38008
retinoic acid nuclear receptor alpha variant 19009
thyroid stimulating hormone receptor3003
nuclear factor erythroid 2-related factor 2 isoform 1110011
Cellular tumor antigen p53100010
Nuclear receptor ROR-gamma4004
Chain A, BCL-2-RELATED PROTEIN A10011
glp-1 receptor, partial3003
Fumarate hydratase4004
TDP1 protein130013
GLI family zinc finger 39009
Smad34004
EWS/FLI fusion protein6006
retinoid X nuclear receptor alpha9009
estrogen-related nuclear receptor alpha9009
farnesoid X nuclear receptor7007
pregnane X nuclear receptor7007
estrogen nuclear receptor alpha110011
G2002
polyprotein4004
67.9K protein6006
peroxisome proliferator-activated receptor delta8008
IDH13003
Histone H2A.x4004
cellular tumor antigen p53 isoform a2002
nuclear factor erythroid 2-related factor 2 isoform 24004
thyroid hormone receptor beta isoform 29009
huntingtin isoform 24004
tyrosine-protein kinase Yes4004
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
nuclear receptor ROR-gamma isoform 17007
geminin8008
survival motor neuron protein isoform d5005
muscleblind-like protein 1 isoform 12002
relaxin receptor 1 isoform 11001
bcl-2-like protein 11 isoform 10011
lamin isoform A-delta105005
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
ATP-binding cassette sub-family C member 30505
Multidrug resistance-associated protein 40506
Bile salt export pump0909
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 2002
Integrin beta-32002
Integrin alpha-IIb2002
Deoxycytidine kinase0045
Adenosine receptor A30101
Rap guanine nucleotide exchange factor 41001
Inositol hexakisphosphate kinase 12002
Canalicular multispecific organic anion transporter 10505
ATPase family AAA domain-containing protein 58008
Ataxin-28008
cytochrome P450 2C9, partial2002
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Ferritin light chain4004
Chain A, Cruzipain2002
interleukin 82002
15-lipoxygenase, partial3003
hypoxia-inducible factor 1 alpha subunit3003
USP1 protein, partial6006
Microtubule-associated protein tau4004
caspase 7, apoptosis-related cysteine protease2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
estrogen receptor 2 (ER beta)8008
progesterone receptor8008
cytochrome P450 family 3 subfamily A polypeptide 46006
glucocorticoid receptor [Homo sapiens]7007
peroxisome proliferator activated receptor gamma5005
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
caspase-32002
RAD510101
euchromatic histone-lysine N-methyltransferase 26006
aryl hydrocarbon receptor6006
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
activating transcription factor 61001
v-jun sarcoma virus 17 oncogene homolog (avian)3003
Caspase-71001
Bloom syndrome protein isoform 13003
vitamin D3 receptor isoform VDRA6006
thyroid hormone receptor beta isoform a3003
caspase-31001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
peripheral myelin protein 226006
cytochrome P450 3A4 isoform 11001
caspase-1 isoform alpha precursor2002
Gamma-aminobutyric acid receptor subunit pi1001
Voltage-dependent calcium channel gamma-2 subunit7007
ATP-dependent translocase ABCB10203
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Glutamate receptor 27007
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Caspase-72002
Spike glycoprotein5016
Gamma-aminobutyric acid receptor subunit alpha-11001
Growth factor receptor-bound protein 20101
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Pantothenate synthetase0101
Discoidin domain-containing receptor 20448
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0101
GABA theta subunit1001
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Gamma-aminobutyric acid receptor subunit epsilon1001
Leukotriene C4 synthase0033
acetylcholinesterase2002
GALC protein2002
GLS protein2002
PPM1D protein3003
nuclear receptor subfamily 1, group I, member 22002
Spike glycoprotein0011
Replicase polyprotein 1ab0011
serine/threonine-protein kinase mTOR isoform 13003
Bone morphogenetic protein receptor type-1B0044
Membrane-associated progesterone receptor component 10033
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0336
Serine/threonine-protein kinase PLK40246
Serine/threonine-protein kinase 250033
ATP-dependent RNA helicase DDX3X0044
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0033
Pyridoxal kinase0044
Citron Rho-interacting kinase0044
Serine/threonine-protein kinase RIO30033
Dual specificity mitogen-activated protein kinase kinase 70033
Serine/threonine-protein kinase Chk10145
Inhibitor of nuclear factor kappa-B kinase subunit beta0135
Peripheral plasma membrane protein CASK0033
Aurora kinase A0347
Cyclin-G-associated kinase0044
Serine/threonine-protein kinase DCLK10033
Inhibitor of nuclear factor kappa-B kinase subunit alpha0134
Muscle, skeletal receptor tyrosine-protein kinase0033
Ephrin type-B receptor 60044
Peroxisomal acyl-coenzyme A oxidase 30044
Mitogen-activated protein kinase 130134
Transmembrane protease serine 20011
3-phosphoinositide-dependent protein kinase 10033
Mitogen-activated protein kinase kinase kinase 130033
Death-associated protein kinase 30033
Mitogen-activated protein kinase kinase kinase 70033
Receptor-interacting serine/threonine-protein kinase 20347
Mitotic checkpoint serine/threonine-protein kinase BUB10044
NUAK family SNF1-like kinase 10134
Dynamin-like 120 kDa protein, mitochondrial0044
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0033
Tyrosine-protein kinase JAK20044
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Eukaryotic translation initiation factor 5B0033
Rho-associated protein kinase 20044
Serine/threonine-protein kinase ULK10044
Serine/threonine-protein kinase/endoribonuclease IRE10044
Ribosomal protein S6 kinase alpha-50044
U5 small nuclear ribonucleoprotein 200 kDa helicase0044
Ribosomal protein S6 kinase alpha-40044
Serine/threonine-protein kinase 160044
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0033
Serine/threonine-protein kinase PAK 30033
Cyclin-dependent kinase-like 50044
Serine/threonine-protein kinase 17B0033
Serine/threonine-protein kinase 100044
Serine/threonine-protein kinase D30044
Cyclin-dependent kinase 140033
Structural maintenance of chromosomes protein 20044
Mitogen-activated protein kinase kinase kinase 60044
Serine/threonine-protein kinase OSR10033
Mitogen-activated protein kinase kinase kinase kinase 40044
Serine/threonine-protein kinase LATS10044
Serine/threonine-protein kinase PAK 40246
Serine/threonine-protein kinase Chk20134
Tyrosine-protein kinase ABL107816
Tyrosine-protein kinase ABL10202
Proto-oncogene tyrosine-protein kinase Src0213
Epidermal growth factor receptor0549
Transthyretin0011
RAF proto-oncogene serine/threonine-protein kinase0538
Receptor tyrosine-protein kinase erbB-20336
High affinity nerve growth factor receptor0044
Guanine nucleotide-binding protein G(i) subunit alpha-20022
ADP/ATP translocase 20044
Cytochrome P450 1A20101
Neuronal proto-oncogene tyrosine-protein kinase Src 0001
Protein kinase C beta type0044
Insulin receptor0347
Tyrosine-protein kinase Lck0549
Proto-oncogene tyrosine-protein kinase LCK 0202
Tyrosine-protein kinase Fyn0246
Cyclin-dependent kinase 10044
Glycogen phosphorylase, liver form0044
Tyrosine-protein kinase Fes/Fps0044
Macrophage colony-stimulating factor 1 receptor0437
Procathepsin L0112
Adenine phosphoribosyltransferase0044
Tyrosine-protein kinase Yes0145
Tyrosine-protein kinase Lyn0145
Proto-oncogene tyrosine-protein kinase receptor Ret0448
Insulin-like growth factor 1 receptor0145
Signal recognition particle receptor subunit alpha0033
Cytochrome c1, heme protein, mitochondrial0044
Hepatocyte growth factor receptor0246
Tyrosine-protein kinase HCK0448
Proto-oncogene tyrosine-protein kinase ROS0033
Platelet-derived growth factor receptor beta06410
Tyrosine-protein kinase Fgr0044
Quinolone resistance protein NorA0101
Wee1-like protein kinase 20033
Uncharacterized serine/threonine-protein kinase SBK30033
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Serine/threonine-protein kinase A-Raf0145
Cytochrome P450 2D60101
Mast/stem cell growth factor receptor Kit06410
Glycogen phosphorylase, brain form0044
Breakpoint cluster region protein03711
Serine/threonine-protein kinase pim-10044
Fibroblast growth factor receptor 10347
Cytochrome P450 2A60101
Cytochrome P450 2C9 0303
Myosin light chain kinase, smooth muscle0033
Cyclin-dependent kinase 40145
ADP/ATP translocase 30044
Inosine-5'-monophosphate dehydrogenase 20044
Angiotensin-converting enzyme 0101
Proto-oncogene tyrosine-protein kinase Src0549
cAMP-dependent protein kinase type II-alpha regulatory subunit0044
Insulin receptor-related protein0033
Serine/threonine-protein kinase B-raf0459
Potassium voltage-gated channel subfamily E member 10202
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0044
Ribosyldihydronicotinamide dehydrogenase [quinone]0044
Platelet-derived growth factor receptor alpha06410
Tyrosine-protein kinase Blk0101
Tyrosine-protein kinase Fer0044
Protein kinase C alpha type0145
cAMP-dependent protein kinase catalytic subunit alpha0044
Vascular endothelial growth factor receptor 1 0336
General transcription and DNA repair factor IIH helicase subunit XPD0044
Interferon-induced, double-stranded RNA-activated protein kinase0033
Casein kinase II subunit alpha'0044
Ras-related protein Rab-6A0044
Serine/threonine-protein kinase MAK0033
Cytochrome P450 2B60101
Cyclin-dependent kinase 11B0033
Ephrin type-A receptor 10044
Fibroblast growth factor receptor 20033
Receptor tyrosine-protein kinase erbB-30033
Multifunctional protein ADE20044
Fibroblast growth factor receptor 40033
Fibroblast growth factor receptor 30033
cAMP-dependent protein kinase catalytic subunit gamma0033
cAMP-dependent protein kinase catalytic subunit beta0044
Ferrochelatase, mitochondrial0044
Ribosomal protein S6 kinase beta-10044
Tyrosine-protein kinase JAK10044
Protein kinase C eta type0033
Cyclin-dependent kinase 20358
Beta-adrenergic receptor kinase 10044
Probable ATP-dependent RNA helicase DDX60044
Activin receptor type-2A0033
Mitogen-activated protein kinase 3 0246
MAP/microtubule affinity-regulating kinase 30044
Mitogen-activated protein kinase 10358
Ephrin type-A receptor 20145
Ephrin type-A receptor 30033
Ephrin type-A receptor 80033
Ephrin type-B receptor 20145
Leukocyte tyrosine kinase receptor0033
Non-receptor tyrosine-protein kinase TYK20044
UMP-CMP kinase 0033
Phosphatidylethanolamine-binding protein 10033
Wee1-like protein kinase0044
Heme oxygenase 20044
Tyrosine-protein kinase receptor UFO0134
Mitogen-activated protein kinase 40033
S-adenosylmethionine synthase isoform type-20044
DnaJ homolog subfamily A member 10044
RAC-alpha serine/threonine-protein kinase0347
RAC-beta serine/threonine-protein kinase0145
G protein-coupled receptor kinase 40033
Cytochrome P450 2C190202
Dual specificity protein kinase TTK0044
DNA replication licensing factor MCM40044
Prostaglandin G/H synthase 20448
Tyrosine-protein kinase receptor Tie-10033
Vascular endothelial growth factor receptor 30336
Vascular endothelial growth factor receptor 206411
Dual specificity mitogen-activated protein kinase kinase 20246
Receptor-type tyrosine-protein kinase FLT30449
Bone morphogenetic protein receptor type-1A0044
Activin receptor type-1B0044
TGF-beta receptor type-10044
Serine/threonine-protein kinase receptor R30044
TGF-beta receptor type-20044
Electron transfer flavoprotein subunit beta0044
Tyrosine-protein kinase CSK0145
Glycine--tRNA ligase0044
Protein kinase C iota type0044
Exosome RNA helicase MTR40044
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0336
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0336
Serine/threonine-protein kinase mTOR0448
Megakaryocyte-associated tyrosine-protein kinase0033
Tyrosine-protein kinase Tec0145
Tyrosine-protein kinase TXK0134
Tyrosine-protein kinase ABL20044
Tyrosine-protein kinase FRK0044
G protein-coupled receptor kinase 60044
Tyrosine-protein kinase ZAP-700033
Tyrosine-protein kinase SYK0145
26S proteasome regulatory subunit 6B0044
Mitogen-activated protein kinase 80044
Mitogen-activated protein kinase 90044
Dual specificity mitogen-activated protein kinase kinase 40033
Dual specificity mitogen-activated protein kinase kinase 30044
Casein kinase I isoform alpha0347
Casein kinase I isoform delta0044
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0336
MAP kinase-activated protein kinase 20145
Cyclin-dependent kinase 80134
Elongation factor Tu, mitochondrial0044
Choline-phosphate cytidylyltransferase A0033
Cysteine--tRNA ligase, cytoplasmic0044
Casein kinase I isoform epsilon0044
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0044
Dual specificity protein kinase CLK10044
Dual specificity protein kinase CLK20044
Dual specificity protein kinase CLK30044
Glycogen synthase kinase-3 alpha0044
Glycogen synthase kinase-3 beta0145
Cyclin-dependent kinase 70044
Cyclin-dependent kinase 90044
Ras-related protein Rab-27A0044
Tyrosine-protein kinase Blk0134
Interleukin-1 receptor-associated kinase 10044
Potassium voltage-gated channel subfamily KQT member 10202
Ribosomal protein S6 kinase alpha-30246
Cytoplasmic tyrosine-protein kinase BMX0033
cAMP-dependent protein kinase catalytic subunit PRKX0033
Serine/threonine-protein kinase Nek20145
Serine/threonine-protein kinase Nek30044
Serine/threonine-protein kinase Nek40033
Tyrosine-protein kinase JAK30033
Dual specificity mitogen-activated protein kinase kinase 60044
Serine/threonine-protein kinase PLK10347
Death-associated protein kinase 10033
LIM domain kinase 10145
LIM domain kinase 20145
Mitogen-activated protein kinase 120134
Mitogen-activated protein kinase 100044
Tyrosine--tRNA ligase, cytoplasmic0044
5'-AMP-activated protein kinase subunit gamma-10045
5'-AMP-activated protein kinase catalytic subunit alpha-20135
Ephrin type-B receptor 30044
Ephrin type-A receptor 50044
Ephrin type-B receptor 40347
Ephrin type-B receptor 10033
Ephrin type-A receptor 40044
Adenylate kinase 2, mitochondrial0044
Adenosine kinase0044
Hormonally up-regulated neu tumor-associated kinase0033
Serine/threonine-protein kinase SIK10235
Receptor-interacting serine/threonine-protein kinase 40033
Ras-related protein Rab-100044
Cell division control protein 2 homolog0033
Actin-related protein 30044
Actin-related protein 20044
Calcium-dependent protein kinase 10033
GTP-binding nuclear protein Ran0044
Tubulin alpha-1A chain0033
Casein kinase II subunit alpha0033
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0033
SRSF protein kinase 20033
Casein kinase I isoform gamma-20044
DNA-dependent protein kinase catalytic subunit0303
Mitogen-activated protein kinase kinase kinase 90033
Serine/threonine-protein kinase PknB0033
Cyclin-dependent kinase 30033
Cyclin-dependent kinase-like 10033
Cyclin-dependent kinase 60145
Cyclin-dependent-like kinase 5 0044
Cyclin-dependent kinase 160044
Cyclin-dependent kinase 170044
Myelin transcription factor 10101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
ATP-dependent 6-phosphofructokinase, platelet type0044
Protein kinase C epsilon type0033
Dual specificity mitogen-activated protein kinase kinase 10347
Angiopoietin-1 receptor0235
Mitogen-activated protein kinase kinase kinase 100033
DNA topoisomerase 2-beta0044
Protein kinase C theta type0044
Activin receptor type-10044
Macrophage-stimulating protein receptor0044
Focal adhesion kinase 10246
Protein kinase C zeta type0145
Protein kinase C delta type0145
Tyrosine-protein kinase BTK0246
Tyrosine-protein kinase receptor TYRO30033
Cyclin-dependent kinase 180044
Activated CDC42 kinase 10145
Epithelial discoidin domain-containing receptor 10347
Tyrosine-protein kinase ITK/TSK0134
Myotonin-protein kinase0033
Potassium voltage-gated channel subfamily H member 20303
Mitogen-activated protein kinase kinase kinase kinase 20044
Mitogen-activated protein kinase kinase kinase 120033
Tyrosine-protein kinase Mer0145
Serine/threonine-protein kinase 40044
5'-AMP-activated protein kinase catalytic subunit alpha-10146
Serine/threonine-protein kinase PAK 10033
Dual specificity mitogen-activated protein kinase kinase 50044
Mitogen-activated protein kinase 70044
Serine/threonine-protein kinase PAK 20044
Serine/threonine-protein kinase 30044
Mitogen-activated protein kinase kinase kinase 10044
cGMP-dependent protein kinase 20033
Integrin-linked protein kinase0044
Rho-associated protein kinase 10044
Non-receptor tyrosine-protein kinase TNK10044
Serine/threonine-protein kinase PRP4 homolog0033
Receptor-interacting serine/threonine-protein kinase 10134
Calcium/calmodulin-dependent protein kinase type II subunit beta0033
Calcium/calmodulin-dependent protein kinase type II subunit gamma0044
Calcium/calmodulin-dependent protein kinase type II subunit delta0044
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0044
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Activin receptor type-2B0044
Bone morphogenetic protein receptor type-20044
Protein-tyrosine kinase 60145
Voltage-dependent L-type calcium channel subunit alpha-1C0202
cGMP-dependent protein kinase 1 0044
Cyclin-dependent kinase 130044
Calcium/calmodulin-dependent protein kinase type 10033
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0044
Protein-tyrosine kinase 2-beta0044
Sodium channel protein type 5 subunit alpha0202
Maternal embryonic leucine zipper kinase0044
Structural maintenance of chromosomes protein 1A0044
Chromodomain-helicase-DNA-binding protein 40044
Peroxisomal acyl-coenzyme A oxidase 10044
Serine/threonine-protein kinase D10033
Serine/threonine-protein kinase 380033
Receptor tyrosine-protein kinase erbB-40033
Ribosomal protein S6 kinase alpha-20033
Ephrin type-A receptor 70033
Delta(24)-sterol reductase0044
Ribosomal protein S6 kinase alpha-10246
Dual specificity testis-specific protein kinase 10044
Myosin light chain kinase, smooth muscle0044
Mitogen-activated protein kinase 110145
Serine/threonine-protein kinase STK110044
Rhodopsin kinase GRK10033
NT-3 growth factor receptor0033
Serine/threonine-protein kinase N10044
Serine/threonine-protein kinase N20044
Mitogen-activated protein kinase 140459
Calcium/calmodulin-dependent protein kinase type IV0044
Mitogen-activated protein kinase kinase kinase 110044
BDNF/NT-3 growth factors receptor0033
Mitogen-activated protein kinase 60044
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0033
AP2-associated protein kinase 10145
Myosin light chain kinase 30044
Uncharacterized aarF domain-containing protein kinase 50033
Serine/threonine-protein kinase SBK10033
Mitogen-activated protein kinase kinase kinase 190033
Putative heat shock protein HSP 90-beta 20044
Serine/threonine-protein kinase TNNI3K0134
Leucine-rich repeat serine/threonine-protein kinase 20134
Serine/threonine-protein kinase MRCK alpha0044
Serine/threonine-protein kinase MRCK gamma0044
Acyl-CoA dehydrogenase family member 100033
Serine/threonine-protein kinase Nek50033
Serine/threonine-protein kinase N30044
Breakpoint cluster region protein0101
Serine/threonine-protein kinase ULK30044
Dual serine/threonine and tyrosine protein kinase0033
Mitogen-activated protein kinase kinase kinase 150033
Uncharacterized protein FLJ452520044
Acyl-CoA dehydrogenase family member 110044
Serine/threonine-protein kinase/endoribonuclease IRE20033
Serine/threonine-protein kinase MARK20044
Serine/threonine-protein kinase TAO10044
STE20-related kinase adapter protein alpha0044
Myosin-140044
AarF domain-containing protein kinase 10044
Serine/threonine-protein kinase tousled-like 20033
Serine/threonine-protein kinase 32C0033
Serine/threonine-protein kinase pim-30033
ATP-dependent RNA helicase DDX420022
Serine/threonine-protein kinase VRK20033
Myosin light chain kinase family member 40033
Homeodomain-interacting protein kinase 10134
Calcium/calmodulin-dependent protein kinase type 1D0033
Mitogen-activated protein kinase kinase kinase kinase 30044
Cyclin-dependent kinase-like 30033
MAP kinase-activated protein kinase 50145
Serine/threonine-protein kinase BRSK20033
Serine/threonine-protein kinase NIM10033
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Serine/threonine-protein kinase ULK20033
Misshapen-like kinase 10044
Serine/threonine-protein kinase DCLK20033
Calcium/calmodulin-dependent protein kinase kinase 10033
Casein kinase I isoform alpha-like0033
Homeodomain-interacting protein kinase 40134
Myosin-IIIa0033
Ankyrin repeat and protein kinase domain-containing protein 10033
Serine/threonine-protein kinase Nek110033
Atypical kinase COQ8A, mitochondrial0044
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0044
Mitogen-activated protein kinase 150044
Serine/threonine-protein kinase Nek90044
Serine/threonine-protein kinase BRSK10033
Serine/threonine-protein kinase 350033
Serine/threonine-protein kinase Nek70033
Rhodopsin kinase GRK70033
Serine/threonine-protein kinase 32A0033
Myosin-IIIb0033
ATP-dependent RNA helicase DDX10044
Dual specificity tyrosine-phosphorylation-regulated kinase 20033
Cyclin-dependent kinase-like 20033
Mitogen-activated protein kinase kinase kinase kinase 10044
Serine/threonine-protein kinase Sgk30033
Atypical kinase COQ8B, mitochondrial0033
Aurora kinase B0246
MAP/microtubule affinity-regulating kinase 40044
Calcium/calmodulin-dependent protein kinase type 1G0044
Serine/threonine-protein kinase Nek10044
Cyclin-dependent kinase 150033
PAS domain-containing serine/threonine-protein kinase0044
Calcium/calmodulin-dependent protein kinase kinase 20044
EKC/KEOPS complex subunit TP53RK0044
Dual specificity testis-specific protein kinase 20033
SRSF protein kinase 10033
Protein cereblon0214
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0246
Mitogen-activated protein kinase kinase kinase 50044
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0033
Mitogen-activated protein kinase kinase kinase 30044
Eukaryotic translation initiation factor 2-alpha kinase 10044
Serine/threonine-protein kinase RIO10033
MAP kinase-interacting serine/threonine-protein kinase 10033
Serine/threonine-protein kinase RIO20033
Cyclin-dependent kinase 190134
Transient receptor potential cation channel subfamily M member 60033
Testis-specific serine/threonine-protein kinase 10033
Angiotensin-converting enzyme 2 0011
Serine/threonine-protein kinase 330033
Nucleolar GTP-binding protein 10044
Serine/threonine-protein kinase D20044
Serine/threonine-protein kinase DCLK30033
NUAK family SNF1-like kinase 20033
RNA cytidine acetyltransferase0044
Serine/threonine-protein kinase SIK20145
Myosin light chain kinase 2, skeletal/cardiac muscle0033
STE20-like serine/threonine-protein kinase 0044
Serine/threonine-protein kinase TAO30044
Homeodomain-interacting protein kinase 20134
Tyrosine-protein kinase Srms0033
Homeodomain-interacting protein kinase 30134
Serine/threonine-protein kinase PLK30235
dCTP pyrophosphatase 10044
Dual specificity protein kinase CLK40044
MAP kinase-interacting serine/threonine-protein kinase 20134
Serine/threonine-protein kinase Nek60033
Casein kinase I isoform gamma-10044
Serine/threonine-protein kinase PAK 60134
SNF-related serine/threonine-protein kinase0033
Serine/threonine-protein kinase LATS20033
Serine/threonine-protein kinase 360033
Phenylalanine--tRNA ligase beta subunit0044
Isoleucine--tRNA ligase, mitochondrial0044
BMP-2-inducible protein kinase0044
Obg-like ATPase 10044
Midasin0044
Interleukin-1 receptor-associated kinase 40044
Serine/threonine-protein kinase 32B0033
Mitogen-activated protein kinase kinase kinase 200044
Cyclin-dependent kinase 120044
Serine/threonine-protein kinase PLK20235
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130033
Serine/threonine-protein kinase MARK10033
Serine/threonine-protein kinase pim-20033
Serine/threonine-protein kinase PAK 50134
Serine/threonine-protein kinase 260044
eIF-2-alpha kinase GCN20033
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0044
Serine/threonine-protein kinase NLK0044
Phosphatidylinositol 4-kinase beta0033
Serine/threonine-protein kinase 17A0033
STE20/SPS1-related proline-alanine-rich protein kinase0033
Ephrin type-A receptor 60033
5'-AMP-activated protein kinase subunit gamma-20045
Serine/threonine-protein kinase TBK10145
Septin-90044
Death-associated protein kinase 20033
Potassium voltage-gated channel subfamily D member 30202
Ribosomal protein S6 kinase alpha-60044
TRAF2 and NCK-interacting protein kinase0044
Serine/threonine-protein kinase tousled-like 10033
Serine/threonine-protein kinase TAO20044
Long-chain-fatty-acid--CoA ligase 50033
ALK tyrosine kinase receptor0134
Broad substrate specificity ATP-binding cassette transporter ABCG20405
SRSF protein kinase 30033
Serine/threonine-protein kinase ICK0044
Cyclin-dependent kinase 11A0033
Aurora kinase C0033
Calcium/calmodulin-dependent protein kinase type II subunit alpha0033
RAC-gamma serine/threonine-protein kinase0145
Serine/threonine-protein kinase 38-like0033
Microtubule-associated serine/threonine-protein kinase 10033
Serine/threonine-protein kinase SIK30145
Mitogen-activated protein kinase kinase kinase 20044
Thyroid hormone receptor-associated protein 30044
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0044
Mitogen-activated protein kinase kinase kinase kinase 50044
Receptor-interacting serine/threonine-protein kinase 30145
Serine/threonine-protein kinase MRCK beta0044
Interleukin-1 receptor-associated kinase 30044
Serine/threonine-protein kinase 240044
NF-kappa-B essential modulator0101
Casein kinase I isoform gamma-30044
Mitogen-activated protein kinase kinase kinase 40044
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Serine/threonine-protein kinase B-raf 0202
Luciferase2002
thioredoxin reductase3003
SMAD family member 23003
SMAD family member 33003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
DNA polymerase iota isoform a (long)4004
DNA repair protein RAD52 homolog isoform a0001
Cytochrome P450 3A40304
Cytochrome P450 2C80001
Cytochrome P450 3A50001
Chain A, membrane-associated prostaglandin E synthase-20101
Chain A, 2-oxoglutarate Oxygenase4004
glucocerebrosidase1001
Parkin1001
bromodomain adjacent to zinc finger domain 2B1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
cytochrome P450 2D6 isoform 11001
peripheral myelin protein 22 isoform 12002
cytochrome P450 2C9 precursor1001
heat shock protein beta-11001
ras-related protein Rab-9A1001
DNA polymerase kappa isoform 13003
M-phase phosphoprotein 83003
neuropeptide S receptor isoform A1001
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Solute carrier family 22 member 60202
Prostaglandin G/H synthase 1 0102
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0101
Albumin0213
Prostaglandin G/H synthase 10203
Neuronal acetylcholine receptor subunit alpha-40101
Interleukin-80101
Androgen receptor0213
Neuronal acetylcholine receptor subunit beta-20101
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 10202
Sodium-dependent dopamine transporter0101
Sodium- and chloride-dependent GABA transporter 10101
Thromboxane-A synthase 0101
Adenosine receptor A10101
Serum paraoxonase/arylesterase 10101
Indoleamine 2,3-dioxygenase 10101
Caspase-10001
Nitric oxide synthase, inducible0101
Adenosine receptor A2a0101
Substance-P receptor0101
Prostaglandin E2 receptor EP3 subtype0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0102
Bifunctional epoxide hydrolase 20303
Prostaglandin G/H synthase 2 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
Histamine H2 receptor3003
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G2002
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30102
Prostaglandin G/H synthase 20202
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Solute carrier family 22 member 60203
Solute carrier family 22 member 70002
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 80203
Multidrug and toxin extrusion protein 10101
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Solute carrier organic anion transporter family member 1B30203
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10303
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
dopamine D1 receptor1001
ClpP1001
phosphopantetheinyl transferase3003
ATAD5 protein, partial1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
chromobox protein homolog 12002
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
flap endonuclease 12002
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
histone acetyltransferase KAT2A isoform 13003
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0202
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Carbonic anhydrase 20314
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
TAR DNA-binding protein 432002
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
ATP-dependent phosphofructokinase3003
endonuclease IV1001
thyroid stimulating hormone receptor1001
nonstructural protein 12002
arylsulfatase A1001
cytochrome P450 2C19 precursor1001
potassium voltage-gated channel subfamily H member 2 isoform d1001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor04211
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Histamine H1 receptor0011
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
pregnane X receptor2002
thioredoxin glutathione reductase1001
Chain A, Beta-lactamase1001
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Polyphenol oxidase 20102
Carbonic anhydrase 120101
5'-AMP-activated protein kinase subunit beta-20001
Carbonic anhydrase 10303
Polymerase acidic protein0011
Carbonic anhydrase 30101
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0202
Carbonic anhydrase 40101
Carbonic anhydrase 60101
Cystathionine gamma-lyase0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 70202
Xanthine dehydrogenase/oxidase0101
Carbonic anhydrase 90202
Carbonic anhydrase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
5'-AMP-activated protein kinase subunit beta-10001
Cell division cycle 7-related protein kinase0033
Nuclear receptor subfamily 1 group I member 20011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Eukaryotic translation initiation factor 4E0011
DNA topoisomerase 2-alpha0033
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Myosin-100033
Alpha-synuclein2002
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0033
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Peptidyl-prolyl cis-trans isomerase FKBP50101
Programmed cell death protein 40011
ATP-dependent RNA helicase DHX300033
Regulatory-associated protein of mTOR0101
Target of rapamycin complex subunit LST80101
Serine/threonine-protein kinase mTOR 0101
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
melanocortin receptor 40112
Platelet-derived growth factor receptor beta0202
5-hydroxytryptamine receptor 1A0101
Aromatase0202
G1/S-specific cyclin-D10101
Cyclin-C0112
5-hydroxytryptamine receptor 2A0101
5-hydroxytryptamine receptor 2C0101
Sodium-dependent serotonin transporter0101
Delta-type opioid receptor0011
5-hydroxytryptamine receptor 70101
Vascular endothelial growth factor receptor 30101
Vascular endothelial growth factor receptor 20101
5-hydroxytryptamine receptor 2B0101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 60101
Protein delta homolog 10123
Fatty-acid amide hydrolase 10101
Serine/threonine-protein kinase ATR0022
MAP kinase-activated protein kinase 30011
Vascular endothelial growth factor receptor 20101
Rab-like protein 30022
Poly [ADP-ribose] polymerase tankyrase-20022
RuvB-like 20112
RuvB-like 10101
Solute carrier family 22 member 1 0101
Mast/stem cell growth factor receptor Kit0101
Translocator protein0101
Beta-adrenergic receptor kinase 10101
Platelet-derived growth factor receptor alpha 0101
G protein-coupled receptor kinase 50101
Mu-type opioid receptor0101
Cyclin-dependent kinase 100011
Serine/threonine-protein kinase ULK30011
NAD-dependent protein deacetylase sirtuin-20101
Bromodomain-containing protein 90011
Serine/threonine-protein kinase 30011
Bromodomain-containing protein 70011
regulator of G-protein signaling 41001
Malate dehydrogenase0101
Chymotrypsinogen B0101
Amine oxidase [flavin-containing] B0101
Inositol monophosphatase 11001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]