Congenital Myasthenia

Synonym
Myasthenia Gravis, Congenital
Presynaptic Congenital Myasthenic Syndromes
Congenital Myasthenia Gravis
Congenital Myasthenic Syndrome
Myasthenic Syndrome, Congenital, Slow-Channel
Congenital Slow-Channel Myasthenic Syndromes
Congenital Slow-Channel Myasthenic Syndrome
Postsynaptic Congenital Myasthenic Syndrome
Postsynaptic Congenital Myasthenic Syndromes
Slow-Channel Congenital Myasthenic Syndrome
Slow-Channel Congenital Myasthenic Syndromes
Congenital Myasthenic Syndromes, Presynaptic
Congenital Myasthenic Syndromes, Postsynaptic
Congenital Myasthenic Syndromes
Myasthenic Syndromes, Congenital, Slow Channel
Congenital Myasthenia
Presynaptic Congenital Myasthenic Syndrome

Excerpt	Reference
"This congenital myasthenic syndrome is for the first time associated with an autosomal translocation 2q31-9p27."	( Crielaard, JM; Hansen, I; Wang, FC; Zeevaert, B, 2002)
"Congenital myasthenic syndromes are caused by different genetic defects affecting proteins expressed at the neuromuscular junction."	( Abicht, A; Bufler, J; Huebner, A; Krampfl, K; Lochmüller, H; Mildner, G; Mortier, W; Petrova, S; Schara, U; Schmidt, C; Stucka, R; Voss, W, 2003)
"Congenital myasthenic syndromes are a genetically and phenotypically heterogeneous group of hereditary disorders affecting neuromuscular junction."	( Akinci, G; Dirik, E; Kurul, SH; Ozden, O; Oztura, I; Yis, U, 2009)
"Congenital myasthenic syndrome is difficult to diagnose, especially in the neonate when classic myasthenic signs may not be present."	( Agus, MS; Burgess, SL; Burpee, TM; Darras, BT; Estrella, E; Kang, PB; Kunkel, LM; Mallory, LA; Nurko, S; Shaw, JG, 2009)
"Fast channel congenital myasthenic syndromes are rare, but frequently result in severe weakness."	( Bailey, S; Beeson, D; Carr, A; Jayawant, S; Lashley, D; McConville, J; Palace, J; Robb, S, 2012)
"Congenital myasthenic syndromes are a heterogeneous group of inherited disorders that arise from impaired signal transmission at the neuromuscular synapse."	( Beeson, D; Belaya, K; Cossins, J; Finlayson, S; Liu, WW; Maslau, S; Maxwell, S; McGowan, SJ; Palace, J; Pascual Pascual, SI; Slater, CR; Twigg, SR; Walls, TJ, 2012)
"Slow channel congenital myasthenic syndrome is a dominant disorder characterized by prolonged acetylcholine receptor ion-channel activation."	( Beeson, D; Finlayson, S; Howard, R; Kullmann, DM; Palace, J; Spillane, J; Webster, R, 2013)
"Slow channel congenital myasthenic syndrome is caused by a genetically determined kinetic anomaly of the acetylcholine receptor at the neuromuscular junction leading to its prolonged open state."	( Abicht, A; Fischer, D; Heinimann, K; Peyer, AK; Sinnreich, M, 2013)
"Congenital myasthenia gravis is caused by genetic mutations affecting neuromuscular transmission, characterized by muscle weakness usually starting in childhood."	( Memon, MN; Nizamani, NB; Talpur, KI, 2013)
"While most congenital myasthenic syndromes are caused by defects in postsynaptic proteins, VAChT deficiency is a presynaptic myasthenic syndrome."	( Aran, A; Gulsuner, S; Hershkovitz, Y; Kaneshige, K; King, MC; Lee, MK; Levy-Lahad, E; Meirson, T; Oliphant, S; Parsons, SM; Renbaum, P; Samson, AO; Segel, R; Walsh, T; Weinberg-Shukron, A; Zeligson, S, 2017)
"The congenital myasthenic syndromes are a heterogeneous group of genetic disorders characterized by an abnormal synaptic transmission in the neuromuscular plate."	( Chávez, G; Engel, AG; Espinoza, IO; Reynoso, C, 2019)
"Slow-channel congenital myasthenic syndrome is an autosomal dominant inherited progressive neuromuscular disorder caused by abnormal gating of mutant acetylcholine receptors in the neuromuscular junction."	( Barros-Angueira, F; Eirís-Puñal, J; Fuentes-Pita, P; Gómez-Lado, C; López-Vázquez, A; Pardo, J; Pérez-Gay, L; Quintas-Rey, R, 2020)
"Congenital myasthenic syndromes are rare hereditary disorders caused by mutations associated with proteins of the neuromuscular junction."	( Ceylaner, S; Deymeer, F; Durmus, H; Hashemolhosseini, S; Sticht, H, 2021)
"Congenital myasthenic syndromes are a group of genetic neuromuscular disorders caused by mutations that impair synaptic transmission at the neuromuscular junction."	( Mukkamala, SG; Pappy, AL; Sirmon, CAF, 2021)
"The slow-channel congenital myasthenic syndrome is an autosomal dominant neuromuscular disorder caused by mutations in different subunits of the acetylcholine receptor."	( Dejthevaporn, C; Engel, AG; Pulkes, T; Rattanasiri, S; Wetchaphanphesat, S; Witoonpanich, R, 2022)

Excerpt	Reference
"The congenital myasthenic syndromes have now been traced to an array of molecular targets at the neuromuscular junction encoded by no fewer than 11 disease genes."	( Engel, AG; Selcen, D; Shen, XM; Sine, SM, 2010)

Excerpt	Reference
"DOK7 (downstream of tyrosine kinase 7) congenital myasthenic syndrome was previously treated successfully with ephedrine and salbutamol; however, both are unavailable in the United States."	( Tsao, CY, 2016)
"DOK7 congenital myasthenic syndrome often presents with limb-girdle muscle weakness, which can become progressive without proper treatment."	( Tsao, CY, 2016)
"DOK7 congenital myasthenic syndrome (DOK7-CMS) generally presents early in life and is treated with salbutamol or ephedrine."	( Basto, JP; Cruz, S; Peres, J; Salgado, V; Santos, L; Santos, M; Tavares, P; Valverde, AH, 2018)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	1 (0.51)	12.5806
2000's	62 (31.31)	18.1394
2010's	99 (50.00)	28.8240
2020's	36 (18.18)	9.53

Drug	Relationship Strength	Studies	Trials
chlorine	low	1	0
glycine	low	6	0
2-aminoethoxydiphenyl borate	low	1	0
4-aminopyridine	medium	16	1
albuterol	low	35	0
verapamil	low	1	0
diazepam	low	1	0
dimethoate	low	1	0
distigmine	low	1	0
edrophonium	low	3	0
flumazenil	low	3	0
fluoxetine	low	13	0
lamotrigine	low	1	0
losartan	low	1	0
mexiletine	low	1	0
midazolam	low	1	0
apnea	low	10	0
neostigmine	low	7	0
propofol	low	1	0
terbutaline	low	1	0
tulobuterol	low	1	0
carbachol	low	1	0
prednisone	low	1	0
amifampridine	medium	17	1
alanine	low	1	0
serine	low	2	0
lysine	low	2	0
leucine	low	2	0
phenylalanine	low	1	0
asparagine	low	2	0
histidine	low	1	0
valine	low	2	0
threonine	low	3	0
isoleucine	low	2	0
arginine	low	4	0
pseudoephedrine	low	1	0
pyridostigmine bromide	medium	37	1
ephedrine	medium	16	2
ethylnitrosourea	low	1	0
phosphotyrosine	low	1	0
glutamic acid	low	1	0
torpedo	low	1	0
colforsin	low	1	0
fomesafen	low	1	0
remifentanil	low	1	0
nicotine	low	2	0
glyoxal bis(2-hydroxyanil)	low	2	0
sr 95531	low	1	0
proline	low	5	0
lithium chloride	low	1	0
leptomycin b	low	1	0
glycogen	low	1	0
inositol 1,4,5-trisphosphate	low	1	0
quinidine	low	7	0
y 27632	low	1	0
quinine	low	1	0
6-cyano-7-nitroquinoxaline-2,3-dione	low	1	0
ramipril	low	1	0
cysteine	low	3	0
emerin	low	1	0
staurosporine	low	1	0
cgp 55845a	low	1	0
tannins	low	1	0
calpain	low	3	0
picrotoxin	low	1	0
piperidines	low	1	0
okadaic acid	low	1	0
calpastatin	low	1	0
exudates	low	1	0
guanosine diphosphate mannose	low	1	0

Protein Targets (663)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
Chain A, Cruzipain	3	0	0	3
15-lipoxygenase, partial	4	0	0	4
phosphopantetheinyl transferase	6	0	0	6
USP1 protein, partial	4	0	0	4
TDP1 protein	16	0	0	16
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
thyroid stimulating hormone receptor	9	0	0	9
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
vitamin D3 receptor isoform VDRA	3	0	0	3
thyroid hormone receptor beta isoform a	2	0	0	2
mitogen-activated protein kinase 1	3	0	0	3
nuclear receptor ROR-gamma isoform 1	4	0	0	4
cytochrome P450 3A4 isoform 1	7	0	0	7
histone acetyltransferase KAT2A isoform 1	3	0	0	3
lethal factor (plasmid)	9	0	0	9
Gamma-aminobutyric acid receptor subunit pi	7	8	2	17
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	7	8	2	17
Gamma-aminobutyric acid receptor subunit delta	7	8	2	17
Gamma-aminobutyric acid receptor subunit gamma-2	7	8	2	17
Gamma-aminobutyric acid receptor subunit alpha-5	7	8	2	17
Gamma-aminobutyric acid receptor subunit alpha-3	7	8	2	17
Gamma-aminobutyric acid receptor subunit gamma-1	7	8	2	17
Gamma-aminobutyric acid receptor subunit alpha-2	7	8	2	17
Gamma-aminobutyric acid receptor subunit alpha-4	7	8	2	17
Gamma-aminobutyric acid receptor subunit gamma-3	7	8	2	17
Gamma-aminobutyric acid receptor subunit alpha-6	7	8	2	17
Histamine H2 receptor	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	7	8	2	17
Gamma-aminobutyric acid receptor subunit beta-3	7	8	2	17
Gamma-aminobutyric acid receptor subunit beta-2	7	8	2	17
Transient receptor potential cation channel subfamily V member 1	0	0	1	2
Transient receptor potential cation channel subfamily V member 3	0	0	0	1
GABA theta subunit	7	8	2	17
Gamma-aminobutyric acid receptor subunit epsilon	7	8	2	17
Transient receptor potential cation channel subfamily V member 2	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	8	0	0	8
thioredoxin reductase	13	0	0	13
RAR-related orphan receptor gamma	5	0	0	5
Microtubule-associated protein tau	5	0	0	5
estrogen receptor 2 (ER beta)	5	0	0	5
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
glucocorticoid receptor [Homo sapiens]	11	0	0	11
cytochrome P450 2D6	6	0	0	6
glucocerebrosidase	3	0	0	3
IDH1	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	20	0	0	20
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
cytochrome P450 2D6 isoform 1	5	0	0	5
chromobox protein homolog 1	7	0	0	7
transcriptional regulator ERG isoform 3	2	0	0	2
thyroid hormone receptor beta isoform 2	10	0	0	10
geminin	11	0	0	11
peripheral myelin protein 22	6	0	0	6
survival motor neuron protein isoform d	2	0	0	2
lamin isoform A-delta10	8	0	0	8
Potassium channel subfamily K member 2	0	3	1	4
Rap guanine nucleotide exchange factor 3	2	0	0	2
Cellular tumor antigen p53	6	0	0	6
Potassium voltage-gated channel subfamily A member 3	0	1	1	2
Acetylcholinesterase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	9	0	9
ATP-dependent phosphofructokinase	8	0	0	8
Glutamate receptor 1	0	3	1	4
Glutamate receptor 2	0	3	1	4
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	3	1	4
Inositol monophosphatase 1	2	0	0	2
Carbonic anhydrase 1	0	2	0	8
Carbonic anhydrase 2	0	2	0	8
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	6	2	10
Proton-coupled amino acid transporter 1	0	6	0	7
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	2
glp-1 receptor, partial	9	0	0	9
GLS protein	8	0	0	8
regulator of G-protein signaling 4	8	0	0	8
estrogen-related nuclear receptor alpha	11	0	0	11
estrogen nuclear receptor alpha	19	0	0	19
NPYLR7B	0	0	1	1
arylsulfatase A	8	0	0	8
thyroid stimulating hormone receptor	5	0	0	5
flap endonuclease 1	5	0	0	5
ATP-binding cassette sub-family C member 3	0	12	0	12
Multidrug resistance-associated protein 4	0	12	0	12
Bile salt export pump	0	17	0	17
Beta-2 adrenergic receptor	0	2	4	6
Beta-1 adrenergic receptor	0	0	3	3
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Beta-3 adrenergic receptor	0	0	2	2
Delta-type opioid receptor	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
Beta-2 adrenergic receptor	0	0	3	9
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Beta-2 adrenergic receptor	0	2	2	4
Canalicular multispecific organic anion transporter 1	0	11	0	11
Chain A, Beta-lactamase	4	0	0	4
aryl hydrocarbon receptor	6	0	0	6
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
POU domain, class 2, transcription factor 1	0	0	0	2
ATAD5 protein, partial	3	0	0	3
Bloom syndrome protein isoform 1	5	0	0	5
D(1A) dopamine receptor	7	0	0	7
neuropeptide S receptor isoform A	1	0	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
NFKB1 protein, partial	2	0	0	2
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	4	0	0	4
DNA polymerase iota isoform a (long)	2	0	0	2
muscarinic acetylcholine receptor M1	8	0	0	8
Cytochrome P450 3A4	0	5	0	6
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Neutral amino acid transporter A	0	3	0	3
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	4
Amino acid transporter	0	3	0	3
acetylcholinesterase	3	0	0	3
GALC protein	2	0	0	2
AR protein	12	0	0	12
peroxisome proliferator activated receptor gamma	9	0	0	9
thyrotropin-releasing hormone receptor	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	4	0	0	4
Neuronal acetylcholine receptor subunit alpha-3	0	3	2	6
Muscarinic acetylcholine receptor M2	0	2	2	5
Muscarinic acetylcholine receptor M4	0	2	2	5
Muscarinic acetylcholine receptor M1	0	3	1	6
Muscarinic acetylcholine receptor M3	0	3	1	5
Muscarinic acetylcholine receptor M4	0	4	0	5
Muscarinic acetylcholine receptor M5	0	3	0	4
Muscarinic acetylcholine receptor M5	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-4	0	5	2	8
Muscarinic acetylcholine receptor M2	0	3	0	4
Muscarinic acetylcholine receptor M1	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-2	0	5	2	8
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	3	2	6
Muscarinic acetylcholine receptor M1	0	1	1	2
Muscarinic acetylcholine receptor M3	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Delta-type opioid receptor	0	2	0	3
Neuronal acetylcholine receptor subunit alpha-6	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-7	0	5	2	8
Sigma non-opioid intracellular receptor 1	0	2	1	3
Muscarinic acetylcholine receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	0	1	3
Muscarinic acetylcholine receptor M2	0	0	0	3
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
Carbonic anhydrase 4	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase 15	0	1	0	3
pregnane X receptor	3	0	0	3
GLI family zinc finger 3	14	0	0	14
nuclear receptor subfamily 1, group I, member 3	8	0	0	8
progesterone receptor	9	0	0	9
retinoic acid nuclear receptor alpha variant 1	7	0	0	7
retinoid X nuclear receptor alpha	3	0	0	3
farnesoid X nuclear receptor	5	0	0	5
pregnane X nuclear receptor	9	0	0	9
G	7	0	0	7
peroxisome proliferator-activated receptor delta	3	0	0	3
vitamin D (1,25- dihydroxyvitamin D3) receptor	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	9	0	0	9
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Voltage-dependent calcium channel gamma-2 subunit	3	0	0	3
Interferon beta	7	0	0	7
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
ATP-dependent translocase ABCB1	0	9	1	21
5-hydroxytryptamine receptor 1A	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	0	1	1
Glutamate receptor 2	3	2	1	6
Adenylate cyclase type 2	0	0	1	1
Adenylate cyclase type 8	0	0	1	1
Adenylate cyclase type 1	0	1	1	2
Inositol hexakisphosphate kinase 1	7	0	0	7
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	4	0	0	4
Relaxin receptor 1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
cytochrome P450 2C9, partial	7	0	0	7
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	4	0	4
Gamma-aminobutyric acid receptor subunit delta	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Fatty acid-binding protein, liver	0	1	0	1
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	0	3	4
Albumin	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	0	5
Gamma-aminobutyric acid receptor subunit beta-1	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	0	7	4	11
Translocator protein	0	3	1	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	7	3	10
5-hydroxytryptamine receptor 1A	0	6	1	7
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	6	3	9
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	1	1	0	2
Gastrin/cholecystokinin type B receptor	1	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	4	4	8
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	3	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	2	6
Gamma-aminobutyric acid receptor subunit beta-2	0	5	2	7
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	4	0	4
Luciferase	4	0	0	4
Histone H2A.x	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
polyadenylate-binding protein 1	0	1	0	1
dopamine D1 receptor	2	0	0	2
Cholinesterase	0	4	0	4
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	5	0	5
67.9K protein	1	0	0	1
interleukin 8	2	0	0	2
activating transcription factor 6	4	0	0	4
endonuclease IV	2	0	0	2
EWS/FLI fusion protein	4	0	0	4
muscleblind-like protein 1 isoform 1	1	0	0	1
Bile salt export pump	0	2	0	2
TAR DNA-binding protein 43	2	0	0	2
caspase 7, apoptosis-related cysteine protease	2	0	0	2
caspase-3	2	0	0	2
Caspase-7	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
caspase-3	1	0	0	1
huntingtin isoform 2	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	6	0	6
Sodium channel protein type 1 subunit alpha	0	3	0	3
Aldo-keto reductase family 1 member B1	0	4	0	4
5-hydroxytryptamine receptor 2C	0	2	0	2
Alpha-2A adrenergic receptor	0	3	0	3
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2D6	0	5	0	5
Cytochrome P450 2C9	0	5	0	5
Angiotensin-converting enzyme	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-1B adrenergic receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Sodium-dependent noradrenaline transporter	0	4	1	5
Sodium-dependent dopamine transporter	0	2	0	2
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
5-hydroxytryptamine receptor 2A	0	4	0	4
5-hydroxytryptamine receptor 2C	0	6	0	6
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium-dependent serotonin transporter	0	4	2	6
Sodium-dependent serotonin transporter	0	2	0	2
Cytochrome P450 2C19	0	1	0	1
Alpha-1A adrenergic receptor	0	2	0	2
D(1A) dopamine receptor	1	0	0	1
5-hydroxytryptamine receptor 6	0	2	0	2
Cytochrome P450 2J2	0	3	0	3
Spike glycoprotein	5	0	0	5
D(2) dopamine receptor	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	1	0	1
Sodium-dependent dopamine transporter	0	2	1	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Cytochrome P450 1B1	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Transporter	0	2	1	4
Histamine H3 receptor	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	2	0	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
Integrin beta-3	0	0	1	1
Integrin alpha-IIb	0	0	1	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	4	2	8
Glutamate receptor ionotropic, NMDA 2B	0	4	2	8
Glutamate receptor ionotropic, NMDA 2C	0	4	2	8
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	4	2	8
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	4	2	8
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	4	2	8
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	6	0	7
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Carbonic anhydrase 12	0	0	0	2
Plasma kallikrein	0	0	0	2
Carbonic anhydrase 3	0	0	0	2
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase 6	0	0	0	2
Adenosine receptor A1	0	0	0	2
Adenosine receptor A2a	0	1	0	3
Carbonic anhydrase 5A, mitochondrial	0	0	0	2
Carbonic anhydrase 7	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase 13	0	0	0	2
Carbonic anhydrase 13	0	0	0	2
Carbonic anhydrase 14	0	0	0	2
Carbonic anhydrase 5B, mitochondrial	0	0	0	2
Chain A, BETA-SPECTRIN	0	0	1	1
Chain A, Phospholipase C Delta-1	0	0	1	1
Chain A, Inositol 1,4,5-trisphosphate receptor type 1	0	0	1	1
Inositol-trisphosphate 3-kinase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	0	2	2
Inositol 1,4,5-trisphosphate receptor type 2	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 3	0	1	1	2
Inositol polyphosphate-5-phosphatase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	1	1	2
peripheral myelin protein 22 isoform 1	1	0	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	3
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	4	0	4
Sodium channel protein type 9 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	2	0	2
Phospholipase A-2-activating protein	0	2	0	2
inositol monophosphatase 1	1	0	0	1
Glycogen synthase kinase-3 beta	0	1	1	2
Neprilysin	0	1	0	1
Angiotensin-converting enzyme	0	3	0	3
Atrial natriuretic peptide receptor 3	0	1	0	1
Thromboxane A2 receptor	0	1	0	2
Type-1A angiotensin II receptor	0	2	1	3
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	1	5
Type-1 angiotensin II receptor	0	1	1	2
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
Squalene synthase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Multidrug and toxin extrusion protein 1	0	2	0	2
Platelet glycoprotein VI	0	1	1	3
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	1	3
Type-1 angiotensin II receptor	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	4	0	4
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 2B	0	6	0	6
Sodium channel protein type 7 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Solute carrier family 22 member 1	0	7	0	9
ATP-dependent translocase ABCB1	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	2	0	2
UDP-glucuronosyltransferase 1-6	0	2	0	2
ATP-dependent translocase ABCB1	0	3	0	4
UDP-glucuronosyltransferase 1A1	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	2	0	2
Acetylcholinesterase	0	2	0	2
Cholinesterase	0	3	0	3
5-hydroxytryptamine receptor 3E	0	1	0	1
Smad3	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Cytochrome P450 1A2	0	1	0	1
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Mu-type opioid receptor	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Nuclear receptor ROR-gamma	2	0	0	2
Acetylcholine-binding protein	0	1	1	2
Mu-type opioid receptor	0	1	0	1
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Solute carrier family 22 member 1	0	5	0	7
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Solute carrier family 22 member 2	0	5	0	5
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Tyrosine-protein kinase Lck	0	0	0	1
Proto-oncogene tyrosine-protein kinase Src	0	0	0	1
Growth factor receptor-bound protein 2	0	0	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	0	0	1
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
thioredoxin glutathione reductase	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
Glucocorticoid receptor	0	2	1	3
Glycine receptor subunit alpha-1	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Glutamate 5-kinase	0	0	0	1
Chain A, Ferritin light chain	1	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
heat shock protein beta-1	1	0	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
RGS12	1	0	0	1
Thrombopoietin	1	0	0	1
pyruvate kinase	1	0	0	1
cytochrome P450 2C9 precursor	2	0	0	2
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Ornithine decarboxylase	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Histidine-rich protein PFHRP-II	0	2	0	2
Cytochrome P450 2D1	0	2	0	2
Cytochrome P450 2D26	0	2	0	2
Cytochrome P450 2D3	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Cytochrome P450 2D4	0	2	0	2
Multidrug resistance protein 1a	0	0	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
DNA polymerase kappa isoform 1	1	0	0	1
Pyruvate kinase PKM	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	0	1
Chain A, Ribosomal protein S6 kinase alpha-1	0	1	0	1
Chain X, Tyrosine-protein kinase Lyn	0	1	0	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Chain A, Arginase 1	0	1	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Histamine H2 receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
Multidrug resistance-associated protein 1	0	2	1	4
D(3) dopamine receptor	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor, alpha form	0	1	0	1
Chain B, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
Rho-associated protein kinase 2	0	2	0	2
Ribosomal protein S6 kinase alpha-5	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
C-C motif chemokine 2	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
cAMP-dependent protein kinase catalytic subunit gamma	0	1	0	1
cAMP-dependent protein kinase catalytic subunit beta	0	1	0	1
Rho-associated protein kinase 1	0	2	0	2
Serine/threonine-protein kinase N2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(17)

Research Excerpts

Overview

Context

Treatment

Research

Studies (198)

Protein Targets (663)

Congenital Myasthenia

Synonyms(17)

Research Excerpts

Overview

Context

Treatment

Research

Studies (198)

Drugs Studied (77)

Protein Targets (663)